Attitude and determination control system of a Satellite with an FPGA

Le but de ce projet est de développer un système d’acquisition et de contrôle de l’orientation d’un satellite de type cubSat, au moyen d’un circuit basé autour d’une FPGA

Ordinateur de bord pour mini satellite

Objectif Développement d’une nouvelle carte électronique pour le sous-système CDMS (Control & Data Management System) du satellite Swisscube, sur la base des résultats de tests du modèle prototype. Ce picosatellite développé entièrement par des étudiants de différentes hautes écoles de Suisse, sera lancé vers la fin de l’année 2008. Résultats Le modèle de qualification du CDMS a été développé et testé. Ces différents tests ont permis de démontrer le bon fonctionnent de la carte pour les différentes fonctionnalités et spécifications requises. La carte du CDMS est entièrement opérationnelle et peu être transmise au team responsable du développement software du CDMS, pour effectuer leurs tests d’intégration. Mots-clés CDMS, CubeSat, Swisscube, microcontrôleur, mémoires, I2C, SPI, OpenOCD, JTAGkey, EclipseZiel Entwurf einer neuen elektronischen Karte für das Subsystem CDMS des Swisscube Satelliten, welche auf die Resultate von Tests des Prototypenmodells basiert ist. Dieser Picosatellit, welcher von Schweizer Fachhochstudenten entwickelt worden ist, wird Ende 2008 gestartet. Resultate Das Qualifikationsmodell des CDMS wurde entwickelt und getestet. Diese Tests erlaubten es, das gute Funktionieren der verschiedenen erforderlichen Funktionalitäten und Spezifizierungen zu beweisen. Die CDMS Karte ist einsatzfähig und kann dem verantwortlichen Team der Entwicklung der CDM -Software weitergeleitet werden, um die Integrationsteste durchzuführen. Schlüsselwörter CDMS, CubeSat, Swisscube, Mikrokontroller, Speicher, I2C, SPI, OpenOCD, JTAGkey, Eclips

Bass loudspeaker control

Stenheim, une entreprise suisse basée à Vétroz, souhaite améliorer la qualité de leurs enceintes audio. Cette thèse consiste en l’étude d’un haut-parleur de basses fréquences et des distorsions qu’il peut produire dans le but de les corriger. Le travail consiste en premier lieu à l’analyse des produits existants permettant la correction de la distorsion. Quelques solutions existent mais aucune ne satisfait pleinement l’entreprise. Une analyse approfondie du fonctionnement du haut-parleur permet ensuite de comprendre les lois physiques qui le régissent. Une modélisation basique du transducteur est ainsi élaborée

Single-cell gene profiling of human regulatory T cell subsets in human graft-versus-host disease

International audiencen.

IL-23 and IL-12 Have Overlapping, but Distinct, Effects on Murine Dendritic Cells

Abstract IL-23 is a recently discovered heterodimeric cytokine that shares biological properties with proinflammatory cytokines. The biologically active heterodimer consists of p19 and the p40 subunit of IL-12. IL-23 has been shown to possess biological activities on T cells that are similar as well distinct from those of IL-12. We have constructed single-chain IL-23 and IL-12 fusion proteins (IL-23-Ig and IL-12-Ig) and have compared the two recombinant proteins for effects on murine dendritic cells (DC). Here we show that the IL-23-Ig can bind a significant proportion of splenic DC of both the CD8α− and CD8α+ subtypes. Furthermore, IL-23and IL-12-Ig exert biological activities on DC that are only in part overlapping. While both proteins induce IL-12 production from DC, only IL-23-Ig can act directly on CD8α+ DC to promote immunogenic presentation of an otherwise tolerogenic tumor peptide. In addition, the in vitro effects of IL-23-Ig did not appear to require IL-12Rβ2 or to be mediated by the production of IL-12. These data may establish IL-23 as a novel cytokine with major effects on APC

Pantograph catenary dynamic optimisation based on advanced multibody and finite element co-simulation tools

This paper presents recent developments undertaken by SNCF Innovation & Research Department on numerical modelling of pantograph catenary interaction. It aims at describing an efficient co-simulation process between Finite Element (FE) and Multibody (MB) modelling methods. FE catenary models are coupled with a full flexible MB representation with pneumatic actuation of pantograph. These advanced functionalities allow new kind of numerical analyses such as dynamic improvements based on innovative pneumatic suspensions or assessment of crash risks crossing areas that demonstrate the powerful capabilities of this computing approach

Improvements to the "sket bottle": a simple manual device for sampling small crustaceans from marine caves and other cryptic habitats

Dark littoral submarine caves can act as enclaves of the deep aphotic zone in shallow coastal areas, and their survey has revealed the existence of a very particular fauna of specialized and poorly known organisms among which crustaceans are particularly well represented. In these particular habitats, the use of conventional sampling techniques, such as hand nets, is often not recommended since they disturb bottom sediments causing hazardous situations to scientific divers. The use of baited traps, while technically possible, is not. always practical is such remote habitats. The present work describes a simple and inexpensive manual device that can be operated by divers ill submarine caves and other cryptic habitats to recurrently catch small motile organisms such as mysid crustaceans, caridean shrimps, or even gobiid fishes. This small suction bottle derived and improved from the original "Sket bottle" design considerably reduces the risks of disturbing the cave's bottom sediment and can be easily operated using a single hand. The described sampling device can also be easily used outside caves, in a variety of particular habitats, e.g., rubble filled bottoms, branching coral reefs, cracks, and small holes on rocky surfaces, in which small motile organisms usually escape from traditional sampling gears, e.g., fishnets and traps, or simply go unnoticed by researchers during sampling.info:eu-repo/semantics/publishedVersio

Abnormal nociception and opiate sensitivity of STOP null mice exhibiting elevated levels of the endogenous alkaloid morphine

<p>Abstract</p> <p>Background-</p> <p>Mice deficient for the stable tubule only peptide (STOP) display altered dopaminergic neurotransmission associated with severe behavioural defects including disorganized locomotor activity. Endogenous morphine, which is present in nervous tissues and synthesized from dopamine, may contribute to these behavioral alterations since it is thought to play a role in normal and pathological neurotransmission.</p> <p>Results-</p> <p>In this study, we showed that STOP null brain structures, including cortex, hippocampus, cerebellum and spinal cord, contain high endogenous morphine amounts. The presence of elevated levels of morphine was associated with the presence of a higher density of mu opioid receptor with a higher affinity for morphine in STOP null brains. Interestingly, STOP null mice exhibited significantly lower nociceptive thresholds to thermal and mechanical stimulations. They also had abnormal behavioural responses to the administration of exogenous morphine and naloxone. Low dose of morphine (1 mg/kg, i.p.) produced a significant mechanical antinociception in STOP null mice whereas it has no effect on wild-type mice. High concentration of naloxone (1 mg/kg) was pronociceptive for both mice strain, a lower concentration (0.1 mg/kg) was found to increase the mean mechanical nociceptive threshold only in the case of STOP null mice.</p> <p>Conclusions-</p> <p>Together, our data show that STOP null mice displayed elevated levels of endogenous morphine, as well as an increase of morphine receptor affinity and density in brain. This was correlated with hypernociception and impaired pharmacological sensitivity to mu opioid receptor ligands.</p