1,538 research outputs found

    Strategies for Enhancing Racially Diverse Student Satisfaction in Graduate-Level Occupational Therapy Programs

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    A survey investigated satisfaction levels of racially diverse, graduate-level OT students at NSU and strategies for enhancing student satisfaction to ultimately meet the OT profession’s diversity goals. Overall, racially diverse students were satisfied with their OT program experience and identified diverse faculty and scholarship opportunities as desired resources needed for continuation in OT programs

    Inducing a thermogenic response to cold shock in Escherichia coli

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    A presentation in the Undergraduate Research Kaleidoscope: Library East Commons Performance Space, November 18, 2010.Runtime: 07:35 minutes.Microorganisms respond to environmental stress through several means for survival. This research project aims to engineer Escherichia coli cells to generate heat in response to a cold-shock. Altering a cell’s reaction to external variations prolongs its

    O fascínio dos cientistas colombianos pela engenharia genética de plantas

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    A biotecnologia e a engenharia genética de plantas têm forte apelo na Colômbia, devido ao potencial que essa tecnologia proporciona para participar da nova economia do conhecimento e também como uma forma de explorar a grande biodiversidade do país. Contudo, a tecnologia de engenharia genética e a produção de conhecimento resultante são dominadas por interesses e recursos do hemisfério norte. Cientistas colombianos que fazem uso da engenharia genética devem trabalhar dentro desse contexto. Ainda assim, muitos acreditam que seus projetos de pesquisa beneficiarão a Colômbia. Essa tecnologia, portanto, oscila entre o otimismo quanto ao seu futuro em potencial e as barreiras impostas pelas condições globais em que ocorre

    Specialist Leaders in Cultural Education (SLICE®) Early Years Fellowships 2019

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    This project, involving five nursery schools across the North West of England is part of a larger scheme run by Curious Minds, Arts Council England’s North West Bridge organisation. SLiCE is a one-year fellowship programme for middle and senior leaders within Teaching School Alliances and Multi-Academy Trusts, and is focused on developing the fellow’s capacity to strategically support cultural education in their own school and across the alliance. This report brings together the findings from the five SLiCE research projects that were run specifically in Early Years settings from 2018-2019. All five SLiCE fellowships had an overall enquiry question: “What role could cultural organisations have in supporting schools to think differently about arts, creativity, and cultural education underpinning the relationships between wellbeing and literacy in the early years?” Curious Minds, who provided the funding resources, were clear that “thinking differently” produced by the collaboration should flow both ways and the role of the SLiCE fellows was to provoke generative practice through this two-way encounter, between a cultural organization and a school. Manchester Metropolitan University were commissioned by Curious Minds to support the research aspect of the projects. Appendix I (page 44) outlines the programme of activities and outputs the researchers planned in order to support the SLiCE Fellows and their cultural partners. SLiCE Fellows and Cultural Organisations Project one: Moving together: a dance collaboratory in the Nursery SLiCE Fellow: Lisa Taylor (Headteacher at Martenscroft Nursery School and Children’s Centre) Cultural Partner: Sam Broadbent (Company Chameleon) Early Year Practitioner: Shabnam Amin (Martenscroft Nursery School and Children’s Centre) Project Two: Will there be fragile things? SLiCE Fellow: Sue Allan (Headteacher at Ribblesdale Nursery School Cultural Partner: Elaine Bates (Manchester Museum) Project Three: Ebbs and flows: moving through the nursery day SLiCE Fellow: Tara Entwistle (Headteacher at Newtown Nursery School) Cultural Partner: Anne O’Connor and Anna Daly (Primed for Life) Project Four: Our Nursery School is in an art gallery SLiCE Fellow: Colette Bentley (Headteacher, East Prescot Road Nursery) Artist: Denise Wright Film-maker: Jake Ryan Early Year Practitioners: Jess Tinsley; Craig Bolton; Moira Kelly; Joan Buckland; Lynne Higginson; Bev Moran; Colette Byrne; Jenn Keeley; and Lesley Addley (East Prescot Road Nursery) Cultural Partner: Debbie Goldsmith and Deborah Riding (Tate Liverpool) Project Five: More than Music: Language, Literacy and Laughter! SLiCE Fellow: Shamim Ashraf (Headteacher at Stoneyholme Nursery School) Cultural Partner: Ben McCabe and Anni Tracy (More Music Morecambe) Research leads: Dr Christina MacRae; Professor Rachel Holmes, Dr Jo McNulty; and Ms Kerry Moakes (Manchester Metropolitan University

    Adolescent menstrual health literacy in low, middle and high-income countries : a narrative review

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    Background: Poor menstrual health literacy impacts adolescents’ quality of life and health outcomes across the world. The aim of this systematic review was to identify concerns about menstrual health literacy in low/middle-income countries (LMICs) and high-income countries (HICs). Methods: Relevant social science and medical databases were searched for peer-reviewed papers published from January 2008 to January 2020, leading to the identification of 61 relevant studies. Results: A thematic analysis of the data revealed that LMICs report detrimental impacts on adolescents in relation to menstrual hygiene and cultural issues, while in HICs, issues related to pain management and long-term health outcomes were reported more frequently. Conclusions: In order to improve overall menstrual health literacy in LMICs and HICs, appropriate policies need to be developed, drawing on input from multiple stakeholders to ensure evidence-based and cost-effective practical interventions

    Analysis of a STEM Education Professional Development Conference for Pre-service Educators

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    Science, technology, engineering, and mathematics (STEM) disciplines are attracting increased attention in education. The iSTEM 2017 conference was a professional development program designed to acquaint pre-service teachers with interdisciplinary, research-based STEM instructional strategies that can transform traditional classroom instruction into dynamic learning environments. The STEM Education Scholars (STEMES) is a Learning Community of Practice, housed in the College of Education, at a midsized mid-western public research university. The program of study focused on designing a professional development program for future Pre-K12 teachers. The iSTEM 2017 conference presented by the STEMES Community of Practice sought to inform pre-service teachers of STEM pedagogy, and focused on innovative classroom resources, hands-on learning and increasing content confidence when incorporating STEM into classroom instruction. iSTEM 2017 was held in February, 2017, and offered twenty refereed presentations and workshop sessions, a keynote address, and a closing session to over 200 pre-service teachers. Conference participants chose sessions, participated in game-like experiences and shared their learning with each other as well as with conference organizers. Results from participant self-reported surveys were analyzed to measure the impact of the conference on improving participants’ confidence in teaching STEM topics, and their attitudes about the instructional methods. These results were added to the conference proceedings, which also contain documentation of each iSTEM 2017 session. Findings suggest that the iSTEM 2017 conference had an overall positive impact on participants’ familiarity with STEM education, their belief in the importance of STEM education, and their confidence to integrate STEM education into future instructional practices

    Claudin-2-dependent Changes in Noncharged Solute Flux Are Mediated by the Extracellular Domains and Require Attachment to the PDZ-scaffold

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    Paracellular transport through the tight junction shows selectivity for both ionic charge and solute size. It is known that charged residues on the extracellular loops of claudins control charge selectivity. It is also known that inducible expression of claudin-2, but not claudin-4, will selectively increase the permeability for PEG molecules which are <4Å in radius, but it is not known whether permeability is controlled by the same regions of claudins which control charge selectivity. Using inducible expression of chimeras of claudin-2 and claudin-4 in monolayers of MDCK II cells we show that the extracellular loops alone are responsible for controlling the permeability for noncharged PEGs as well as for charge selectivity. Further, the cytoplasmic C-terminal PDZ-binding motif is required for wild type claudin-2 to control permeability, suggesting a requirement for attachment to the PDZ scaffold in order to form pores. These observations support a model where the loops form pores controlling permeability for both charged and noncharged solutes which are smaller than 4Å. They leave unanswered why both claudin-2 and -4 can influence electrical properties while only -2 can selectively increase permeability for small PEGs

    Dynamic optical coherence tomography of blood vessels in cutaneous melanoma — correlation with histology, immunohistochemistry and dermoscopy

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    Dermoscopy adds important information to the assessment of cutaneous melanoma, but the risk of progression is predicted by histologic parameters and therefore requires surgery and histopathologic preparation. Neo-vascularization is crucial for tumor progression and worsens prognosis. The aim of this study was the in vivo evaluation of blood vessel patterns in melanoma with dynamic optical coherence tomography (D-OCT) and the correlation with dermoscopic and histologic malignancy parameters for the risk assessment of melanoma. In D-OCT vessel patterns, shape, distribution and presence/type of branching of 49 melanomas were evaluated in vivo at three depths and correlated with the same patterns in dermoscopy and with histologic parameters after excision. In D-OCT, blood vessel density and atypical shapes (coils and serpiginous vessels) increased with higher tumor stage. The histologic parameters ulceration and Hmb45- and Ki67-positivity increased, whereas regression, inflammation and PD-L1-positivity decreased with risk. CD31, VEGF and Podoplanin correlated with D-OCT vasculature findings. B-RAF mutation status had no influence. Due to pigment overlay and the summation effect, the vessel evaluation in dermoscopy and D-OCT did not correlate well. In summary, atypical vessel patterns in melanoma correlate with histologic parameters for risk for metastases. Tumor vasculature can be noninvasively assessed using D-OCT before surgery

    A experiência de si: o sentir/pensar no contexto da pandemia

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     La investigación “Formación Cultural y Educación inclusiva: ampliando horizontes y disminuyendo barreras”, basada en la perspectiva de la Teoría Crítica, creó el Portfolio “Escrita de Si” a partir de producciones culturales, que provocan el pensamiento crítico y el abordaje sensible de la vida, con vistas a la formación de sí. Se trata de un producto teórico-metodológico que engloba la formación de subjetividades inclusivas ancladas en las dimensiones de accesibilidad y sensibilidad. Así, tiene como objetivo aprehender los sentidos y los significados experienciados  por todas las vidas humanas, independientemente de sus especificidades, en el contexto de la pandemia de la COVID -19. Operando con la contingencia de esta crisis humanitaria, el Portfolio se configura como un instrumento de resistencia, por posibilitar experiencias de sentir/pensar, que configuran un proceso de entendimiento, de conocimiento y de formación, posibilitando que las experiencias sean significativas y reverberan en acciones, dando sentido a lo que somos y a lo que nos acontece.   A pesquisa "Formação Cultural e Educação inclusiva: ampliando horizontes e diminuindo barreiras"[1], baseada na perspectiva da Teoria Crítica, criou o Portfólio “Escrita de Si” a partir de produções culturais, que provocam o pensamento crítico e a abordagem sensível da vida, com vistas à formação de si. Trata-se de um produto teórico-metodológico que engloba a formação de subjetividades inclusivas ancoradas nas dimensões de acessibilidade e sensibilidade. Assim, tem como objetivo apreender os sentidos e os significados experienciados por todas as vidas humanas, independentemente de suas especificidades, no contexto da pandemia da COVID-19. Operando com a contingência desta crise humanitária, o Portfólio se configura como um instrumento de resistência, por possibilitar experiências de sentir/pensar, que configuram um processo de entendimento, de conhecimento e de formação, possibilitando que as experiências sejam significativas e reverberem em ações, dando sentido ao que somos e ao que nos acontece. &nbsp; [1] Pesquisa contemplada com bolsa de iniciação científica da Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro - FAPERJ
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