Effects of Exercise Intensity on Post-Exercise Oral Glucose Tolerance Test Response

Please refer to the pdf version of the abstract located adjacent to the title

LC Circuits for Diagnosing Embedded Piezoelectric Devices

A recently invented method of nonintrusively detecting faults in piezoelectric devices involves measurement of the resonance frequencies of inductor capacitor (LC) resonant circuits. The method is intended especially to enable diagnosis of piezoelectric sensors, actuators, and sensor/actuators that are embedded in structures and/or are components of multilayer composite material structures

System and Method for Monitoring Piezoelectric Material Performance

A system and method are provided for monitoring performance capacity of a piezoelectric material that may form part of an actuator or sensor device. A switch is used to selectively electrically couple an inductor to the piezoelectric material to form an inductor-capacitor circuit. Resonance is induced in the inductor-capacitor circuit when the switch is operated to create the circuit. The resonance of the inductor-capacitor circuit is monitored with the frequency of the resonance being indicative of performance capacity of the device's piezoelectric material

Solvent extraction studies of coprocessing flowsheets: results from Campaign 5 of the Solvent Extraction Test Facility (SETF)

In Campaign 5, fast breeder reactor (FBR) fuel [average burnup {similar_to}2.6 TJ/kg ({similar_to}30,000 MWd/t)] was processed for the first time. Operations in a single extraction cycle with 30% TBP-NPH were satisfactory with low heavy-metal losses (< 0.02%) and high decontamination factors (DFs > 1000) for all fission products except {sup 95}Zr, which exhibited moderate DFs (180 and 750, respectively, in two runs). The use of a split scrub stream (0.5 M and 3 M HNO{sub 3}) vs a single scrub stream (3 M HNO{sub 3}) resulted in the higher DF. An extractant backscrubbing stream was not needed to produce partially partitioned uranium-plutonium products containing 30 to 35% plutonium when processing the core FBR fuel (22% Pu). The necessary enrichment factor ({similar_to}1.5) was attained by maintaining the temperature at 25 to 30{sup 0}C in partial partitioning and adjusting the relative flow rates of the aqueous and organic phases. The plutonium recovery in the two runs ({similar_to}400 g) was purified by anion exchange and converted to PuO{sub 2} for fuel refabrication studies. 8 references, 7 figures, 6 tables

Waste treatment at the Radiochemical Engineering Development Center

At the Radiochemical Engineering Development Center (REDC) irradiated targets are processed for the recovery of valuable radioisotopes, principally transuranium nuclides. A system was recently installed for treating the various liquid alkaline waste streams for removal of excess radioactive contaminants at the REDC. Radionuclides that are removed will be stored as solids and thus the future discharge of radionuclides to liquid low level waste tank storage will be greatly reduced. The treatment system is of modular design and is installed in a hot cell (Cubicle 7) in Building 7920 at the REDC where preliminary testing is in progress. The module incorporates the following: (1) a resorcinol-formaldehyde resin column for Cs removal, (2) a cross flow filtration unit for removal of rare earths and actinides as hydroxide, and (3) a waste solidification unit. Process flowsheets for operation of the module, key features of the module design, and its computer-assisted control system are presented. Good operability of the cross flow filter system is mandatory to the successful treatment of REDC wastes. Results of tests to date on the operation of the filter in its slurry collection mode and its slurry washing mode are presented. These tests include the effects of entrained organic solvent in the waste stream feed to the filter

Solvent extraction studies with intermediate-burnup Fast Flux Test Facility fuel in the Solvent Extraction Test Facility

In Campaign 8, two batches of irradiated fuel from the Fast Flux Test Facility (FFTF) were processed, using 30% TBP-NPH, in the Solvent Extraction Test Facility (SETF). The burnups were about 36 and 55 MWd/kg with 1.3- and 1-year cooling times, respectively. The latter fuel had the highest burnup and shortest cooling time of any fuel ever handled in the SETF. No major problems were noted during the operation of the mixer-settlers, and low uranium and plutonium losses (<0.02%) were achieved. Zirconium and ruthenium decontamination factors (DFs) were improved by increasing the number of scrub stages and increasing the peak solvent loading in the coextraction-coscrub bank. The use of an in-line photometer to measure the uranium and plutonium concentrations in a process stream permitted high solvent loadings of heavy metals to be achieved in the extraction bank while maintaining low losses to the aqueous raffinate. The investigation of two flowsheet options for making separate uranium and plutonium products (organic backscrub and selective uranium extraction) that was started in Campaign 7 was continued. High-quality products were again obtained (uranium and plutonium DFs of {similar_to}0{sup 4}). Plutonium reoxidation was still extensive even though hydrazine was added to the aqueous strip for the organic backscrub flowsheet. Two different plutonium oxalate precipitation procedures [Pu(III) and Pu(IV)] were used in the preparation of the plutonium oxide products; this was done so that the fuel fabrication characteristics of the oxide from the two procedures could be compared. A total of {similar_to}50 g of plutonium was recovered and shipped to the fuel refabrication program

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.

Relation of the Pequot Warres (1660)

Lion Gardener (1599-1663) was an English military engineer, formerly in the service of the prince of Orange, who was hired by members of the Connecticut Company in 1635 to oversee construction of fortifications for their new colony. On arriving in Connecticut in early 1636, his first assignment was to finish and garrison Saybrook Fort, at the mouth of the Connecticut River. In August 1636, the area was visited by a punitive military expedition from the Massachusetts Bay Colony, led by John Endicott, intent upon intimidating the Pequot and Niantic tribes and demanding delivery of the killers of a group of Indian traders (John Stone, Walter Norton, and six crewmen), who had been killed late in 1633. Endicott’s force plundered and burned crops and villages and returned to Boston, touching off the Pequot War that lasted until the fall of 1637. Gardener’s command of Saybrook Fort placed him in the center of the action, and his military background made him an astute observer and critic. Gardener’s Relation of the Pequot Warres was written in 1660, and it remained in manuscript in various Connecticut record collections until rediscovered in 1809 and printed in the Massachusetts Historical Society Collections in 1833 (3rd Series, III, pp. 131–160). The version presented here was republished from the surviving manuscript by the Acorn Club of Connecticut in 1901, and is said to be a more faithful rendering of Gardener’s original. The 33-page Relation is preceded by a 29-page introduction that gives a brief sketch of Gardener’s life and a longer description of the history and provenance of the manuscript. Gardener’s Relation is one of four contemporary English accounts of the Pequot War; the others are by John Underhill, John Mason, and Philip Vincent, the last derived from an unidentified informant

Basic statistics for the behavioral sciences : instructor's resource manual with test items

v, 152 tr. ; 28 c

The Effects of Energy Drinks on Anaerobic Human Performance and Mood

Please view abstract in the attached PDF file