213 research outputs found

    Health Literacy in the Everyday Lives of Older Adults in Greece, Hungary, and the Netherlands

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    Health literacy (HL) encompasses someone’s knowledge and abilities to access and use health information in order to make appropriate health decisions in life. HL is particularly valuable in later life when health challenges grow. An individual’s HL is typically considered a fixed and skills-based characteristic, without taking into account how these are situated in the context of everyday life. Also, lay perspectives on health literacy are relatively scarce. Therefore, the aim of this article is to explore the context-specific perspectives of older adults and health professionals on HL in later life in Greece, Hungary, and the Netherlands. We adopted a qualitative methodology and conducted 12 focus groups: seven with 50 older adults and five with 30 health professionals to gain insight into individual perspectives on HL as situated in the health care and everyday life contexts. An informed grounded theory approach was used in analyzing the data. The results are structured in three themes: (1) interactions with health professionals, (2) perceived quality of the health care system, and (3) managing health in the context of everyday life. An overarching finding is that, for older adults, HL reflects the demands placed on them when managing their health. In the experience of older adults, these demands are placed upon them by healthcare professionals, the healthcare system, as well as their everyday lives. Our findings underscore the importance of Critical Health Literacy (CHL) as that concept foregrounds that HL is context specific. Also, CHL has been argued to be a community characteristic, which is why we call for community-based approaches to improve H

    Ischemic Preconditioning Blunts Loss of Knee Extensor Torque Complexity with Fatigue

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    Introduction: Neuromuscular fatigue reduces the temporal structure, or complexity, of muscle torque output, purportedly through an effect on motor unit behaviour. Ischaemic pre-conditioning (IPC), an emerging ergogenic aid, has been demonstrated to have a potent effect on muscular output and endurance. We therefore tested the hypothesis that IPC would attenuate the fatigueinduced loss of muscle torque complexity. Methods: Ten healthy participants (6 male/4 female) performed intermittent isometric knee extension contractions (6 s contraction, 4 s rest) to task failure at 40% maximal voluntary contraction (MVC). Contractions were preceded by either IPC (three bouts of 5 minutes proximal thigh occlusion at 225 mmHg, interspersed with 5 minutes rest) or SHAM (as IPC, but occlusion at only 20 mmHg) treatments. Torque and EMG signals were sampled continuously. Complexity and fractal scaling were quantified using approximate entropy (ApEn) and the detrended fluctuation analysis (DFA) α scaling exponent. Muscle oxygen consumption (mV̇O2_2) was determined using near-infrared spectroscopy. Results: IPC increased time to task failure by 43 ± 13% (mean ± SEM, P = 0.047). Complexity decreased in both trials (decreased ApEn, increased DFA α; both P < 0.001), though the rate of decrease was significantly lower following IPC (ApEn, –0.2 ± 0.1 vs. –0.4 ± 0.1, P = 0.013; DFA α, 0.2 ± 0.1 vs. 0.3 ± 0.1, P = 0.037). Similarly, the rates of increase in EMG amplitude (P = 0.022) and mV̇O2_2 (P = 0.043) were significantly slower following IPC. Conclusion: These results suggest the ergogenic effect of IPC observed here is of neural origin and accounts for the slowing of the rates of change in torque complexity, EMG amplitude and muscle oxygen consumption as fatigue develops

    Only watching others making their experiences is insufficient to enhance adult neurogenesis and water maze performance in mice

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    In the context of television consumption and its opportunity costs the question arises how far experiencing mere representations of the outer world would have the same neural and cognitive consequences than actively interacting with that environment. Here we demonstrate that physical interaction and direct exposition are essential for the beneficial effects of environmental enrichment. In our experiment, the mice living in a simple standard cage placed in the centre of a large enriched environment only indirectly experiencing the stimulus-rich surroundings (IND) did not display increased adult hippocampal neurogenesis. In contrast, the mice living in and directly experiencing the surrounding enriched environment (DIR) and mice living in a similar enriched cage containing an uninhabited inner cage (ENR) showed enhanced neurogenesis compared to mice in control conditions (CTR). Similarly, the beneficial effects of environmental enrichment on learning performance in the Morris Water maze depended on the direct interaction of the individual with the enrichment. In contrast, indirectly experiencing a stimulus-rich environment failed to improve memory functions indicating that direct interaction and activity within the stimulus-rich environment are necessary to induce structural and functional changes in the hippocampus

    Early Parental Positive Behavior Support and Childhood Adjustment: Addressing Enduring Questions with New Methods

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    A large literature provides strong empirical support for the influence of parenting on child outcomes. The current study addresses enduring research questions testing the importance of early parenting behavior to children's adjustment. Specifically, we developed and tested a novel multi‐method observational measure of parental positive behavior support at age 2. Next, we tested whether early parental positive behavior support was related to child adjustment at school age, within a multi‐agent and multi‐method measurement approach and design. Observational and parent‐reported data from mother–child dyads (N = 731; 49 percent female) were collected from a high‐risk sample at age 2. Follow‐up data were collected via teacher report and child assessment at age 7.5. The results supported combining three different observational methods to assess positive behavior support at age 2 within a latent factor. Further, parents' observed positive behavior support at age 2 predicted multiple types of teacher‐reported and child‐assessed problem behavior and competencies at 7.5 years old. Results supported the validity and predictive capability of a multi‐method observational measure of parenting and the importance of a continued focus on the early years within preventive interventions.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110827/1/sode12103.pd

    Hur fungerar olika gummigolv i grisningsboxen praktiskt och hur Àr suggans liggbeteende pÄ gummi- jÀmfört med betonggolv?

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    Gummigolv pÄ den fasta betongytan installerades i ett antal grisningsboxar med syfte att förbÀttra djurhÀlsa och komfort för bÄde smÄgrisar och suggor. I detta Fakta-blad presenteras erfarenheter frÄn de testade gummigolven samt resultat frÄn suggornas beteende i jÀmförelse med betonggolv. Totalt testades och jÀmfördes tre olika gummimaterial i grisningsboxarna under fem grisningsomgÄngar. Hur lÄng tid suggorna stod eller lÄg och var suggorna befann sig i grisningsboxen studerades med hjÀlp av dygnsvisa videoinspelningar ca 1 vecka respektive 3 veckor efter grisningen. Sammanfattningsvis konstaterades att suggornas liggbeteende inte pÄverkades negativt av gummimaterialen, snarare tvÀrtom. Den mjukare gummimattan bedömdes som bÀst ur komfortsynpunkt. HÄllbarheten hos gummimassabelÀggningen var inte tillrÀckligt bra och den hÄrdare gummimattan upplevdes som hal vid grisningen för bÄde sugga och personal

    Structural basis for cell surface patterning through NetrinG-NGL interactions

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    Brain wiring depends on cells making highly localized and selective connections through surface protein-protein interactions, including those between NetrinGs and NetrinG ligands (NGLs). The NetrinGs are members of the structurally uncharacterized netrin family. We present a comprehensive crystallographic analysis comprising NetrinG1-NGL1 and NetrinG2-NGL2 complexes, unliganded NetrinG2 and NGL3. Cognate NetrinG-NGL interactions depend on three specificity-conferring NetrinG loops, clasped tightly by matching NGL surfaces. We engineered these NGL surfaces to implant custom-made affinities for NetrinG1 and NetrinG2. In a cellular patterning assay, we demonstrate that NetrinG-binding selectivity can direct the sorting of a mixed population of NGLs into discrete cell surface subdomains. These results provide a molecular model for selectivity-based patterning in a neuronal recognition system, dysregulation of which is associated with severe neuropsychological disorders
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