390 research outputs found
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Synoptic-scale precursors of extreme UK summer 3-hourly rainfall
This is the final version. Available on open access from AGU via the DOI in this recordThe synoptic-scale meteorological conditions leading up to the 30 most extreme sub-daily summer rain events for two regions of the UK (north-west and south-east) were examined for the period 1979-2013. Using a recently available, quality controlled, national hourly rain gauge dataset, we were able to identify extreme 3-hour rainfall accumulations that may be indicative of flash flooding. Composites of the state of the atmosphere leading up to these dates were produced to investigate synoptic-scale processes, thus potentially allowing for them to be identified in coarse resolution re-analyses and in climate models. The results show that the two regions have different dominant synoptic-scale conditions leading to extreme 3-hour rainfall, which is thought to be related to the type of rainfall typically experienced in each region. In particular, positive anomalies in mean sea level pressure and the geopotential height at 200hPa over the UK are associated with extreme rainfall in the north-west, where the position of the westerly jet is also important. For the south-east, no clear anomalous synoptic-scale conditions could be identified, however localised moisture sources and unstable air masses were observed in association with extremes. These results indicate the importance of better understanding of both synoptic-scale and thermodynamic drivers of short-duration extreme rainfall, with potential implications in forecasting and flood warning, as well as for understanding the representation of key processes by regional climate models.Natural Environment Research Council (NERC)European Research CouncilWolfson FoundationRoyal Societ
The future of midlatitude cyclones
This is the final version. Available from the publisher via the DOI in this record.Purpose of Review This review brings together recent research on the structure, characteristics, dynamics, and impacts of
extratropical cyclones in the future. It draws on research using idealized models and complex climate simulations, to evaluate
what is known and unknown about these future changes.
Recent Findings There are interacting processes that contribute to the uncertainties in future extratropical cyclone changes, e.g.,
changes in the horizontal and vertical structure of the atmosphere and increasing moisture content due to rising temperatures.
Summary While precipitation intensity will most likely increase, along with associated increased latent heating, it is unclear to
what extent and for which particular climate conditions this will feedback to increase the intensity of the cyclones. Future research
could focus on bridging the gap between idealized models and complex climate models, as well as better understanding of the
regional impacts of future changes in extratropical cyclones.Natural Environment Research Council (NERC
Savannahs of Asia: Antiquity, biogeography, and an uncertain future
The savannahs of Asia remain locally unrecognized as distinctive ecosystems, and continue to be viewed as degraded forests or seasonally dry tropical forests. These colonial-era legacies are problematic, because they fail to recognize the unique diversity of Asian savannahs and the critical roles of fire and herbivory in maintaining ecosystem health and diversity. In this review, we show that: the palaeo-historical evidence suggests that the savannahs of Asia have existed for at least 1 million years, long before widespread landscape modification by humans; savannah regions across Asia have levels of C4 grass endemism and diversity that are consistent with area-based expectations for non-Asian savannahs; there are at least three distinct Asian savannah communities, namely deciduous broadleaf savannahs, deciduous fine-leafed and spiny savannahs and evergreen pine savannahs, with distinct functional ecologies consistent with fire- and herbivory-driven community assembly. Via an analysis of savannah climate domains on other continents, we map the potential extent of savannahs across Asia. We find that the climates of African savannahs provide the closest analogues for those of Asian deciduous savannahs, but that Asian pine savannahs occur in climates different to any of the savannahs in the southern continents. Finally, we review major threats to the persistence of savannahs in Asia, including the mismanagement of fire and herbivory, alien woody encroachment, afforestation policies and future climate uncertainty associated with the changing Asian monsoon. Research agendas that target these issues are urgently needed to manage and conserve these ecosystems. This article is part of the themed issue ‘Tropical grassy biomes: linking ecology, human use and conservation’
Comparison of six fit algorithms for the intra-voxel incoherent motion model of diffusion-weighted magnetic resonance imaging data of pancreatic cancer patients.
The intravoxel incoherent motion (IVIM) model for diffusion-weighted imaging (DWI) MRI data bears much promise as a tool for visualizing tumours and monitoring treatment response. To improve the currently poor precision of IVIM, several fit algorithms have been suggested. In this work, we compared the performance of two Bayesian IVIM fit algorithms and four other IVIM fit algorithms for pancreatic cancer imaging. DWI data were acquired in 14 pancreatic cancer patients during two MRI examinations. Three different measures of performance of the fitting algorithms were assessed: (i) uniqueness of fit parameters (Spearman's rho); (ii) precision (within-subject coefficient of variation, wCV); and (iii) contrast between tumour and normal-appearing pancreatic tissue. For the diffusivity D and perfusion fraction f, a Bayesian fit (IVIM-Bayesian-lin) offered the best trade-off between tumour contrast and precision. With the exception for IVIM-Bayesian-lin, all algorithms resulted in a very poor precision of the pseudo-diffusion coefficient D* with a wCV of more than 50%. The pseudo-diffusion coefficient D* of the Bayesian approaches were, however, significantly correlated with D and f. Therefore, the added value of fitting D* was considered limited in pancreatic cancer patients. The easier implemented least squares fit with fixed D* (IVIM-fixed) performed similar to IVIM-Bayesian-lin for f and D. In conclusion, the best performing IVIM fit algorithm was IVM-Bayesian-lin, but an easier to implement least squares fit with fixed D* performs similarly in pancreatic cancer patients
Evolutionary dynamics and biogeography of Musaceae reveal a correlation between the diversification of the banana family and the geological and climatic history of Southeast Asia
Article PurchasedTropical Southeast Asia, which harbors most of the Musaceae biodiversity, is one of the most species-rich regions in the world. Its high degree of endemism is shaped by the region's tectonic and climatic history, with large differences between northern Indo-Burma and the Malayan Archipelago. Here, we aim to find a link between the diversification and biogeography of Musaceae and geological history of the Southeast Asian subcontinent. The Musaceae family (including five Ensete, 45 Musa and one Musella species) was dated using a large phylogenetic framework encompassing 163 species from all Zingiberales families. Evolutionary patterns within Musaceae were inferred using ancestral area reconstruction and diversification rate analyses. All three Musaceae genera - Ensete, Musa and Musella - originated in northern Indo-Burma during the early Eocene. Musa species dispersed from 'northwest to southeast' into Southeast Asia with only few back-dispersals towards northern Indo-Burma. Musaceae colonization events of the Malayan Archipelago subcontinent are clearly linked to the geological and climatic history of the region. Musa species were only able to colonize the region east of Wallace's line after the availability of emergent land from the late Miocene onwards
Reviewing, indicating, and counting books for modern research evaluation systems
In this chapter, we focus on the specialists who have helped to improve the
conditions for book assessments in research evaluation exercises, with
empirically based data and insights supporting their greater integration. Our
review highlights the research carried out by four types of expert communities,
referred to as the monitors, the subject classifiers, the indexers and the
indicator constructionists. Many challenges lie ahead for scholars affiliated
with these communities, particularly the latter three. By acknowledging their
unique, yet interrelated roles, we show where the greatest potential is for
both quantitative and qualitative indicator advancements in book-inclusive
evaluation systems.Comment: Forthcoming in Glanzel, W., Moed, H.F., Schmoch U., Thelwall, M.
(2018). Springer Handbook of Science and Technology Indicators. Springer Some
corrections made in subsection 'Publisher prestige or quality
Host-Pathogen O-Methyltransferase Similarity and Its Specific Presence in Highly Virulent Strains of Francisella tularensis Suggests Molecular Mimicry
Whole genome comparative studies of many bacterial pathogens have shown an overall high similarity of gene content (>95%) between phylogenetically distinct subspecies. In highly clonal species that share the bulk of their genomes subtle changes in gene content and small-scale polymorphisms, especially those that may alter gene expression and protein-protein interactions, are more likely to have a significant effect on the pathogen's biology. In order to better understand molecular attributes that may mediate the adaptation of virulence in infectious bacteria, a comparative study was done to further analyze the evolution of a gene encoding an o-methyltransferase that was previously identified as a candidate virulence factor due to its conservation specifically in highly pathogenic Francisella tularensis subsp. tularensis strains. The o-methyltransferase gene is located in the genomic neighborhood of a known pathogenicity island and predicted site of rearrangement. Distinct o-methyltransferase subtypes are present in different Francisella tularensis subspecies. Related protein families were identified in several host species as well as species of pathogenic bacteria that are otherwise very distant phylogenetically from Francisella, including species of Mycobacterium. A conserved sequence motif profile is present in the mammalian host and pathogen protein sequences, and sites of non-synonymous variation conserved in Francisella subspecies specific o-methyltransferases map proximally to the predicted active site of the orthologous human protein structure. Altogether, evidence suggests a role of the F. t. subsp. tularensis protein in a mechanism of molecular mimicry, similar perhaps to Legionella and Coxiella. These findings therefore provide insights into the evolution of niche-restriction and virulence in Francisella, and have broader implications regarding the molecular mechanisms that mediate host-pathogen relationships
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