Comparative Analysis of Skin Cancer Image with Classification and Clustering Algorithms

Skin cancer is one of the most common and potentially life-threatening diseases worldwide. Early detection and accurate diagnosis are crucial for effective treatment and improved patient outcomes. In recent years, the integration of advanced technologies, such as artificial intelligence and image analysis, has revolutionized the field of dermatology. This article presents a comprehensive comparative analysis of algorithms for classifying and clustering skin cancer images. The goal is to improve the accuracy and efficiency of skin cancer diagnosis. The study explores various machine learning algorithms used for skin cancer image classification, such as support vector machines (SVM), decision trees, and k-nearest neighbors (KNN). These algorithms are evaluated based on their capacity to distinguish between benign and malignant skin lesions, with a particular emphasis on sensitivity, specificity, and accuracy. Apart from classification, clustering algorithms are also examined to determine their potential in grouping similar skin lesions. This can assist dermatologists in identifying patterns and anomalies within extensive datasets. K-means, hierarchical clustering, and DBSCAN are among the algorithms assessed for their effectiveness in organizing images of skin cancer. The comparative analysis in this article aims to provide insights into the strengths and weaknesses of various algorithms, their computational efficiency, and their performance on diverse datasets. Furthermore, it explores the potential of combining classification and clustering techniques to develop a skin cancer diagnosis system that is more robust and accurate

Ipsilateral olecranon and distal radius fracture: A case report

WOS: 000397094300056PubMed ID: 25544490INTRODUCTION: Concomitant ipsilateral olecranon and distal radius fracture are rare injuries. Their clinical presentation is unusual and investigation and management is poorly described. PRESENTATION OF CASE: We present a 55-year-old woman patient who fell off sustaining a concomitant distal radius and olecranon fracture in the same extremity. On examination, there was gross swelling of the proximal and distal forearm and no neurovascular deficit. Radiographs confirmed distal radius and olecranon fracture. Patient was treated with open reduction and anatomic locking plate for olecranon and a closed reduction percuteneous K wire fixation with penning fixator for distal radius fracture. After physical therapy program, functional results were good and DASH score was 60. DISCUSSION: Several different combinations of fracture with dislocation have been described, but, to our knowledge, concurrent ipsilateral olecranon and distal radius fracture has not been reported before. In the literature review there are two similar cases in the English literature. CONCLUSION: Ipsilateral olecranon and distal radius fracture is a very rare injury due to different trauma mechanisms. However we should keep in mind that there may be adjacent joints and structures for concomitant injuries

Adjuvant Corticosteroid Therapy in Hepatosplenic Candidiasis-Related Iris

Candida infections are the most frequent infections in neutropenic patients. Hepatosplenic candidiasis (HSC) is a part of disseminated Candida infection that occurs most commonly in patients with hematologic malignancies treated with chemotherapy and requires protracted antifungal therapy. During invasive mycosis with rapid resolution of immunosuppression, immune reconstitution inflammatory syndrome (IRIS) which mimics treatment failure, drug toxicity or breakthrough infections may occur. Manifestation period, histopathologic findings and favorable effect of steroids to its inflammatory symptoms strongly suggest that HSC belongs to the invasive fungal infection induced IRIS. We present a child with B cell-acute lymphoblastic leukemia who developed HSC and addition of corticosteroid therapy to antifungal treatment achieved rapid resolution of the clinical symptoms and laboratory findings

Quality of Life After Open Surgical versus Endovascular Repair of Abdominal Aortic Aneurysms

Conclusion: Despite anatomical advantages and acceptable mid-phase mortality in patients with high- or medium-risk for open surgery, EVAR did not exhibit a quality of life superiority over open surgery in terms of physical function and patient comfort at or after postoperative six months

Quality of Life After Open Surgical versus Endovascular Repair of Abdominal Aortic Aneurysms

Conclusion: Despite anatomical advantages and acceptable mid-phase mortality in patients with high- or medium-risk for open surgery, EVAR did not exhibit a quality of life superiority over open surgery in terms of physical function and patient comfort at or after postoperative six months

Comparison of apparent diffusion coefficient values among different MRI platforms: a multicenter phantom study

PURPOSE:We aimed to compare apparent diffusion coefficient (ADC) values among magnetic resonance imaging (MRI) scanners from different vendors.MATERIALS AND METHODS:We used a custom-made phantom solution consisting of distilled water, 0.9% NaCl, 25% NaCl, and shampoo for diffusion-weighted MRI (DW-MRI) examinations. DW-MRI was performed with similar sequence parameters using six different 1.5 Tesla MR scanners (scanners A–F). ADC maps were automatically constructed for all DW-MR images (b factors of 0 and 1000 s/mm2). ADC measurements were performed using regions of interest and seven different software programs, including four different postprocessing workstations, two different picture archiving and communication systems, and operator console software for each MR scanner.RESULTS:The ADC values generated by scanners A and F were higher and those of scanner B were lower than those generated by the other scanners (P = 0.002). The intravendor difference in the ADC values averaged from scanners D, E, and F was statistically significant (P < 0.001). The difference between the ADC values obtained by scanners C and E was not statistically different (P = 0.15).CONCLUSION:ADC values may differ among different MRI systems used for DW-MRI. Thus, the MRI vendor should be considered when using DW-MRI in a clinical setting

Association of serum and follicular fluid leptin and ghrelin levels with in vitro fertilization success

 Objectives: The aim of this study was to evaluate the relationship between in vitro fertilization (IVF) cycle outcomes, serum and follicular fluid (FF) levels of leptin and ghrelin. Material and methods: Forty-four women who underwent intracytoplasmic sperm injection cycles (ICSI) were enrolled in the study. On the third day (D3) of the menstrual cycle, venous blood samples were drawn for serum measurements of leptin and ghrelin. The follicular fluid (FF) and the corresponding oocyte were obtained from a single dominant preovulatory follicle at the time of oocyte pick-up. The FF and D3 serum leptin and ghrelin concentrations were measured by enzyme-linked immunosorbent assay. The relationship between pregnancy rate and serum, follicular fluid levels of leptin and ghrelin were analyzed. Results: Of the 44 cases included, nineteen achieved clinical pregnancy (43.18%). Follicular fluid ghrelin levels were significantly lower in the pregnant group than non-pregnant group (p &lt; 0.05) With respect to FF leptin, there was no statistically significant differences between the pregnant and non-pregnant women (p &gt; 0.05). There was no statistically significant difference in D3 serum ghrelin between pregnant and non-pregnant groups (p &gt; 0.05). However, D3 serum leptin levels were significantly lower in pregnant women than non-pregnant women (p &lt; 0.05). Conclusions: Lower ghrelin levels in the follicular fluid were associated with higher pregnancy rates. Also, D3 serum leptin levels were inversely correlated with clinical pregnancy rates. These findings support the potential role of these molecules on IVF outcomes

Deflection of concrete structures reinforced with FRP bars.

yesThis paper presents an analytical procedure based on the stiffness matrix method for deflection prediction of concrete structures reinforced with fiber reinforced polymer (FRP) bars. The variation of flexural stiffness of cracked FRP reinforced concrete members has been evaluated using various available models for the effective moment of inertia. A reduced shear stiffness model was also employed to account for the variation of shear stiffness in cracked regions. Comparisons between results obtained from the proposed analytical procedure and experiments of simply and continuously supported FRP reinforced concrete beams show good agreement. Bottom FRP reinforcement at midspan section has a significant effect on the reduction of FRP reinforced concrete beam deflections. The shear deformation effect was found to be more influential in continuous FRP reinforced concrete beams than simply supported beams. The proposed analytical procedure forms the basis for the analysis of concrete frames reinforced with FRP concrete members

Gender differences in diabetes self-care in adults with type 1 diabetes: Findings from the T1D Exchange clinic registry

Aims To evaluate gender differences in diabetes self-care components including glycemic, blood pressure and lipid control, utilization of diabetes technologies and acute diabetes complications in adults with type 1 diabetes. Methods A total of 9,481 participants >18 years were included in the analysis, 53% were female. Variables of interest included glycemic control measured by HbA1c, systolic/diastolic blood pressures, presence of dyslipidemia, insulin delivery modality, and rates of acute complications. Results Glycemic control was similar in women and men (mean HbA1c in both groups: 8.1% ± 1.6% (64 ± 16 mmol/mol), (p = 0.54). More women used insulin pump therapy (66% vs. 59%, p < 0.001) but use of sensor technology was similar (p < = 0.42). Women had higher rates of diabetic ketoacidosis (DKA) (5% vs. 3%, p < 0.001) and eating disorders (1.7% vs. 0.1%, p < 0.001). Severe hypoglycemia rates were not different between men and women (p = 0.42). Smoking (6% vs 4%, p < 0.001), systolic (125 ± 14.2 vs. 121 ± 14.4, p < 0.001) and diastolic blood pressure (73.3 ± 9.5 vs. 72.2 ± 9.3, p < 0.001) and rate of dyslipidemia (28% vs. 23%, p < 0.001) were higher in men. Conclusion While glycemic control in type 1 diabetes was similar regardless of gender, rates of DKA and eating disorders were higher in women while rates of smoking, hypertension and dyslipidemia were higher in men