69 research outputs found

    Prenatal diagnosis and postnatal follow-up of congenitally corrected transposition of the great arteries and recurrent supraventricular tachycardia

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    The prenatal sonographic diagnosis of congenitally corrected transposition of the great arteries (ccTGA), a rare form of congenital heart disease is very difficult. A24-year-old woman was referred to our center at 28 weeks’ gestation because of suspected fetal cardiac anomalies. This article reports a case of ccTGA with supraventricular tachycardia, ventricular septal defect, pulmonary valve stenosis, tricuspid valvar displacement and moderate tricuspid regurgitation during her pregnancy. The combined presence of SVT and ccTGA are occasionally present in the literature.peer-reviewe

    Atherosclerosis burden and coronary artery lesion complexity in acute coronary syndrome patients

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    Background: Syntax score (SS) is a prognostic marker in patients with acute coronary sydromes (ACS). Carotid intima media thickness (CIMT) and cardio ankle vascular index (CAVI) are well known surrogate marker of atherosclerosis burden. But association between atherosclerosis burden and coronary artery disease (CAD) complexity in ACS patients has not been investigated yet. Methods and Results: Consecutive patients with first time diagnosis of ACS (n = 172) were enrolled. SS, a marker of CAD complexity, was assessed by dedicated computer software. CIMT was examined by B-mode ultrasound. CAVI was assessed by VaSera VS-1000 cavi instrument. SS for low, intermediate and high tertiles of CIMT value were 10.1 ± 8.2 vs 11.4 ± ± 7.9 and 15.2 ± 8.8; p = 0.02). SS for normal, borderline and abnormal CAVI values were 4 ± 3.7 vs 11.1 ± 7.2 and 14.1 ± 9.1, respectively p = 0.009). Also, there was independent association between SS and CIMT (95% coinfidence interval [CI] 2.1–19, p = 0.014) and CAVI (95% CI 15–29, p = 0.021]. Neither traditional cardiovascular risk factor nor thrombolysis in myocardial infarction (TIMI) risk score was independent determinant of SS. Conclusions: We have shown that patients with higher atherosclerosis burden have more complex coronary artery lesions. Also these patients may be identified early by using surrogate markers of atherosclerosis. Its clinical significance requires further research

    The Significance of Hounsfield Unit and Tumor Diameter in the Differentiation of Malignant and Benign Adrenal Masses

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    Aim: The Hounsfield unit (HU) used in non-contrast computed tomography (CT) imaging can predict adrenal masses. In the literature, a HU measurement of >10 on non-contrast CT has been reported to have a wide range of sensitivity (33-72%) in detecting malignancy in patients with adrenal masses, and the size of malignant masses is >4 cm in approximately 90% of cases. The current study investigated the role of the HU value and tumor diameter measured on preoperative CT imaging in the differentiation of benign and malignant masses. Methods: Data analysis was conducted on patients undergoing adrenalectomy for adrenal masses at two different tertiary care centers between January 1, 2019 and January 1, 2023. Patients who underwent an adrenalectomy non-contrast CT scans were assessed for HU and tumor size. The patients were divided into two groups according to histopathologically confirmed benign or malignant masses. Statistical analysis, including receiver operating characteristic curve assessment, was performed to evaluate the diagnostic accuracy. Results: The study included 108 patients, of whom 66.7% (n=72) were female and 33.3% (n=36) were male. The mean age was 51.01±14.01 years. The laparoscopic technique was used in 72 patients, the robotic technique in 17, and the open technique in 19. The mean length of hospital stay was 4 (2-37) days. The mean tumor size was 55 (10-230) mm. The mean operative time was 80 (50-180) minutes. The mean amount of intraoperative blood loss was 40 (20-300) milliliters. The surgical method, tumor diameter, operative time, amount of intraoperative blood loss, and HU value of the mass statistically significantly differed between the groups (p<0.001). We found that the cut-off values of HU and tumor diameter for distinguishing malignant masses from benign masses were 30.5 and 72.5 mm, respectively. At a cut-off value of 30.5 or above, HU had a sensitivity of 100% and a specificity of 81.6% in identifying malignant masses, whereas a sensitivity of 100% and a specificity of 88.7% were determined for malignant masses with a tumor size of 72.5 mm or above. Conclusion: The HU value and tumor diameter were crucial for distinguishing between benign and malignant adrenal masses, enhancing diagnostic accuracy, and informing treatment decisions

    Volume CXIV, Number 4, November 7, 1996

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    Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls. This study aimed to systematically investigate the key clinical features of TS in relationship to karyotype in a large pediatric Turkish patient population.Methods: Our retrospective study included 842 karyotype-proven TS patients aged 0-18 years who were evaluated in 35 different centers in Turkey in the years 2013-2014.Results: The most common karyotype was 45,X (50.7%), followed by 45,X/46,XX (10.8%), 46,X,i(Xq) (10.1%) and 45,X/46,X,i(Xq) (9.5%). Mean age at diagnosis was 10.2±4.4 years. The most common presenting complaints were short stature and delayed puberty. Among patients diagnosed before age one year, the ratio of karyotype 45,X was significantly higher than that of other karyotype groups. Cardiac defects (bicuspid aortic valve, coarctation of the aorta and aortic stenosis) were the most common congenital anomalies, occurring in 25% of the TS cases. This was followed by urinary system anomalies (horseshoe kidney, double collector duct system and renal rotation) detected in 16.3%. Hashimoto's thyroiditis was found in 11.1% of patients, gastrointestinal abnormalities in 8.9%, ear nose and throat problems in 22.6%, dermatologic problems in 21.8% and osteoporosis in 15.3%. Learning difficulties and/or psychosocial problems were encountered in 39.1%. Insulin resistance and impaired fasting glucose were detected in 3.4% and 2.2%, respectively. Dyslipidemia prevalence was 11.4%.Conclusion: This comprehensive study systematically evaluated the largest group of karyotype-proven TS girls to date. The karyotype distribution, congenital anomaly and comorbidity profile closely parallel that from other countries and support the need for close medical surveillance of these complex patients throughout their lifespa

    The investigation of magnetic levitation performances of single grain YBCO at different temperatures

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    Celik, Sukru/0000-0002-6918-7569; GUNER, SAIT BARIS/0000-0001-7487-4817WOS: 000397994700032The temperature dependence of the magnetic levitation force has been investigated for single-grain YBCO bulk sample, 20 mm in diameter with a thickness of 8 mm, fabricated by top-seeded melt growth (TSMG) method using Nd123 seeded. the superconducting properties of the single grain YBCO bulk are studied by VSM (Vibrating Sample Magnetometer), the microstructures and the phase constituents of those that are seen by SEM (Scanning Electron Microscope) and XRD (X-ray Diffraction). the measurements of superconducting properties indicated that magnetic levitation forces of the sample were found 11.23, 10.81, 10.34, 9.23 and 7.02 N at the temperatures of 37, 47, 57, 67 and 77, respectively, and the values of the onset critical temperature (Tc) and the zero-field critical current density (Jc) are 89.3 K and 5.6 x 10(4) A/cm(2) at 77 K, respectively. This research is intended to help for the large scale superconductor levitation performances at different temperatures. (C) 2017 Elsevier B. V. All rights reserved.Recep Tayyip Erdogan University Scientific Research Projects Coordination Department [2014.102.01.05]; TUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [110T622]All the authors would like to thank Dr. Hari Babu Nadendla (at Brunel University, London, UK) for the sample preparation method developed by him, Dr. Yunhua Shi (at Cambridge University, Cambridge, UK) and Kenta Nakazato (at Shibaura Institute of Technology, Tokyo, Japan) for his support and encouragement. This research was supported by the Recep Tayyip Erdogan University Scientific Research Projects Coordination Department (Project Number: 2014.102.01.05). All the magnetic levitation force measurements were performed in the MLFMS designed by the project of TUBITAK (Project Number: 110T622) and whose patent application number is 2013/13638 for the Turkish Patent Institute (TPE)

    Lateral Force Measurements for (Gd123)(1-x) :(Gd211) (x) Superconductors at Different Temperatures

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    Cansiz, Ahmet/0000-0002-3988-6561; GUNER, SAIT BARIS/0000-0001-7487-4817; Ozturk, Kemal/0000-0002-8847-1880WOS: 000399178700028The lateral levitation force between melt-textured (Gd123)(1-x) :(Gd211) (x) bulk superconductors for x = 0.0, 0.1, 0.2, 0.3, 0.4, and 0.5 and a permanent magnet is measured at 30, 40, 50, 60, and 77 K under zero-field-cooling and field-cooling conditions. the variations on the observed levitation force are correlated to the varied content of Gd211 in these melt-textured samples.Recep Tayyip Erdogan University Scientific Research Projects Coordination Department [2012.102.01.1]This research was supported by the Recep Tayyip Erdogan University Scientific Research Projects Coordination Department (project number: 2012.102.01.1). All the magnetic levitation force measurements were performed in the MLFMS designed by the project of TUBITAK (project number: 110T622) and whose patent application number is 2013/13638 for the Turkish Patent Institute (TPE)

    The comparison of levitation and lateral force of bulk and cut-pasted bulk GdBCO samples at different temperatures

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    Celik, Sukru/0000-0002-6918-7569; GUNER, SAIT BARIS/0000-0001-7487-4817; Ozturk, Kemal/0000-0002-8847-1880; ABDIOGLU, MURAT/0000-0002-5497-0817WOS: 000512377800117In this work, in the first time, we have investigated the levitation and lateral force properties of bulk and cut-pasted bulk GdBCO samples at different temperatures and different cooling heights (CH) to determine the effect of cut-pasted process on the magnetic levitation force behaviour. the measurements of superconducting characteristics indicated that the attractive and repulsive force values of cut-pasted GdBCO sample are slightly lesser than those of GdBCO bulk sample. the maximum repulsive and attractive force values obtained as 15.45 N and -4.56 N for GdBCO bulk and as 14.78 N and -3.92 N for cut-pasted GdBCO samples at 37 K. Although there are many fabrication methods as melt-textured growth (MTG), top seeded infiltration growth (TSIG) and TSMG to produce large HTS samples, the desired large sample size and the sample shape compatible with the superconducting magnetic bearing systems are not still sufficient for the technological applications. in this study, the performed cut-pasted process and obtained magnetic levitation force data can be using for the increment sample size and the desired sample shape in the needed different geometry and size for superconducting magnetic bearing systems. (C) 2020 Elsevier B.V. All rights reserved.Scientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [110T622]I would like to thank Prof. Dr. Hari Babu Nadendla (at Brunel University London, UK), Dr. Yunhua Shi and Prof. Dr. David Cardwell (at Cambridge University, Cambridge, UK) for their support and encouragement. All the magnetic levitation force measurements were carried out in the MLFMS made by the project of the Scientific and Technological Research Council of Turkey (TUBITAK) Project No: 110T622 (Patent application number is 2013/13638)

    Micromorphological study of Centaurea L. (Asteraceae); some taxa of eight sections analysed with scanning electron microscopy and light microscopy

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    This study deals with the pollen morphological characterization of 36 taxa (Sections; Cheirolepis 3, Cynaroides 14, Rhizocalathium 5, Grossheimia 3, Chartolepis 3, Pseudophaeopappus 1, Plumosipappus 1 and Phaeopappus 6) belonging to the genus Centaurea. Pollen slides were prepared using the Acetolysis technique. Light Microscope examination showed pollen grains to be tricolporate, isopolar, radially symmetrical, oblate-spheroidal, prolate-spheroidal, subprolate, tectum perforate and scabrate. We identified two basic types of pollen grains, designated type I (Scabrate), type II (Microechinate). 34 taxa evaluated resemble Wagenitz's Jacea pollen type and 2 taxa Montana pollen type. We present micrographs of pollen grains, together with descriptions of the characteristics of their structure. We found that the pollen characters (shape, exine structure, sculpturing) were useful for classification

    Peripheral facial paralysis during the COVID-19 pandemic

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    The mechanism surrounding idiopathic peripheral facial nerve paralysis remains unclear, though viral infections and even immunizations have been suspected of its origin. Thus, the relationship between COVID-19 and facial paralysis should be studied. With this research, we aimed to investigate the characteristics of facial paralysis during the COVID-19 illness as well as the relationship between facial paralysis and COVID-19, the length of time needed for recovery, concurrence with COVID-19 infection, and whether facial paralysis is a late complication or initial symptom of the disease. Forty-five patients thought to have had idiopathic peripheral facial paralysis were included in the study. Pure tone audiometry, COVID-19 PCR tests, and contrast-enhanced ear MRIs were performed on all participants. A standard prednisolone treatment protocol was followed. Participants were monitored for one month; we recorded whether they had COVID-19 previously, initially, or contracted it within the one-month testing period. At the same time, facial paralysis recovery rates were recorded and used in statistical analyses. PCR test at initial admission was reported as positive for COVID-19 in only one participant (2.2%). We discovered an improvement delay regarding facial paralysis in participants who had had COVID-19 previously (p [Med-Science 2022; 11(2.000): 666-71

    The Effect of Magnetic Field Distribution and Pole Array on the Vertical Levitation Force Properties of HTS Maglev Systems

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    ABDIOGLU, MURAT/0000-0002-5497-0817; Celik, Sukru/0000-0002-6918-7569; Ozturk, Kemal/0000-0002-8847-1880WOS: 000368472800001In this paper, the levitation force measurements have been carried out by the magnetic force measurement system under both field-cooling and zero-field-cooling regimes, whereas the magnetic field distribution over the permanent-magnet guide-way (PMG) was calculated by numerical analysis based on the finite-element method. It was shown in this study that the vertical levitation capability and stability of Maglev systems can be improved depending on the cooling regime, pole number, and suitable arrangement of the PMG. in this paper, it was shown that when the pole number increases, the levitation force density increases. It also appeared that the reasonable position of the supplementary permanent magnet and appropriate cooling heights are key parameters for both levitation performance and stabilization of the high-temperature superconductor (HTS) Maglev. It is believed that the numerical and experimental data in this paper are useful for relative design and practical application of HTS Maglev systems.Scientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [112T090, 110T622]This work was supported in part by the Scientific and Technological Research Council of Turkey (TUBITAK) under Project 112T090 and under Project 110T622. This paper was recommended by Associate Editor P. J. Masson
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