611 research outputs found
El legado arqueológico perdido de la antigua "Urso": noticias historiográficas del siglo XVIII a los albores del XX
Este trabajo hace un recorrido por las noticias historiográficas del siglo XVIII a inicios
del siglo XX, sobre el patrimonio arqueológico de la primitiva Urso, en su mayoría perdido en
la actualidad.This paper explores the historical news since the XVIIIth to XXth century, referring to
archaeological items from Urso (Osuna, Sevilla) unknown at presen
Magnetorheological behavior of magnetite covered clay particles in aqueous suspensions
Montmorillonite clay particles coated with magnetite nanoparticles suspended in aqueous media behave as magnetorheological fluids with enhanced stability as compared to conventional ones. In this work, the study of the magnetorheological behavior of these suspensions of magnetite-clay composite particles has been carried out. For this purpose, both steady and dynamic rheological measurements were carried out in the absence and in the presence of external magnetic fields. In the first kind of experiments, the rheograms of the suspensions (shear stress versus shear rate plot) are analyzed as a function of the strength of the magnetic field applied. In the second one, oscillatory stresses are applied to the system, and the storage modulus is studied as a function of the external magnetic field. In the absence of magnetic field, the suspensions develop a weak yield stress due to the aggregation of the magnetite covered clay particles. In the presence of magnetic field, the yield stress is strongly dependent on the magnetic field strength inside the samples, demonstrating that the suspensions experience a magnetorheological effect, moderate when the magnetic field strength is weak and stronger for values of magnetic field higher than 150–200 kA/m. Actually, the most intriguing result is the change of the trend in the dependence of the yield stress with the field. This dependence is approximately linear with the field for strength values smaller than 150–200 kA/m. On the other hand, for higher values, the yield stress increases with magnetic field following a power law with exponent 4.5.The results are interpreted by means of a model that relates the structure of the particles in the suspensions to the magnetic field applied and using the interaction energy between particles calculated by the extended DLVO theory to include magnetic interaction.Financial support by Ministerio de Ciencia e Innovación (Spain) under project No FIS2009-07321, and Junta de Andalucía (Spain) under Project Nos. P08-FQM-3993 and P09-FQM-4787 is gratefully acknowledge
Ejercicios de gramática árabe. Nivel A1 MCER. Cuaderno 1: sustantivos y adjetivos
Cuaderno de ejercicios gramaticales dedicado al sustantivo y adjetivo árabes en el nivel A1 del Marco común europeo de referencia (MCER). Se abordan los siguientes temas relacionados con el sustantivo y el adjetivo: género y número, concordancia sustantivo-adjetivo y posición, adjetivo de relación y adjetivo de color. Los ejercicios van introducidos por una breve explicación gramatical y se encuentran dispuestos de menor a mayor dificultad. Se incluyen además dos anexos: el vocabulario empleado traducido al español y la clave de soluciones
Ejercicios de gramática árabe. Nivel A1 MCER. Cuaderno 2: numerales
Cuaderno de ejercicios gramaticales dedicado a los numerales árabes en el nivel A1 del Marco común europeo de referencia (MCER). Los ejercicios van introducidos por una breve explicación gramatical y se encuentran dispuestos de menor a mayor dificultad. Se incluyen además dos anexos: el vocabulario empleado traducido al español y la clave de soluciones
Apuntes para una antropología del espacio. Consideraciones desde la geografía clásica a la geografía cultural
Actualmente se ha desarrollado un campo de la antropología que dedica sus esfuerzos al estudio del espacio, el presente es una contribución a la teoría antropológica que se fundamenta en los aportes de la geografía vinculados con la sociología y la antropología, asimismo reconocer las propuestas de diversos autores, en la tradición clásica alemana y francesa, quienes han señalado que la reflexión teórica debe partir de la relación entre el espacio y la sociedad, retomando los importantes aportes de la escuela posibilista de Vidal de la Blache en Francia, de la antropogeografía de Ratzel, la sociología urbana R. Park, H. Lefevbre y otros, que buscaron explicar el comportamiento espacial de las sociedades modernas. Para lo cual se propone el término de espacio funcional antropógeno, obtenido con base en la reconstrucción teórica de nociones como espacio, paisaje, territorio, región y lugar, desde una perspectiva sociocultural
Experience with the use of Rituximab for the treatment of rheumatoid arthritis in a tertiary Hospital in Spain: RITAR study
There is evidence supporting that there are no
relevant clinical differences between dosing rituximab 1000 mg or 2000 mg
per cycle in rheumatoid arthritis (RA) patients in clinical trials, and low-dose
cycles seem to have a better safety profile. Our objective was to describe the
pattern of use of rituximab in real-life practice conditions.
Methods: Rituximab for RA in clinical practice (RITAR) study is a retrospective cohort study from 2005 to 2015. Eligibility criteria were RA adults
treated with rituximab for active articular disease. Response duration was
the main outcome defined as months elapsed from the date of rituximab
first infusion to the date of flare. A multivariable analysis was performed
to determine the variables associated with response duration.
Results: A total of 114 patients and 409 cycles were described, 93.0%
seropositive and 80.7% women. Rituximab was mainly used as second-line
biological therapy. On demand retreatment was used in 94.6% of cases
versus fixed 6 months retreatment in 5.4%. Median response duration
to on demand rituximab cycles was 10 months (interquartile range,
7–13). Multivariable analysis showed that age older than 65 years, number
of rituximab cycles, seropositivity, and first- or second-line therapy were
associated with longer response duration. The dose administered at each
cycle was not significantly associated with response duration.
Conclusions: Our experience suggests that 1000 mg rituximab single infusion on demand is a reasonable schedule for long-term treatment of those
patients with good response after the first cycles, especially in seropositive
patients and when it is applied as a first- or second-line biological therap
The Variscan gabbros from the Spanish Central System: A case for crustal recycling in the sub-continental lithospheric mantle?
The gabbroic intrusions that crop out along the Spanish Central System (SCS) are geochemically
heterogeneous, including primitive and evolved rocks. Differentiation is mainly related to fractionation of
Cr-spinel and olivine, but mixing with coeval granitic magmas or crustal assimilation may have also played a
role in the evolution of the most differentiated rocks. The most primitive uncontaminated gabbros show arclike
trace element chondrite and primitive-mantle normalised patterns, characterised by large ion lithophile
elements (LILE)-light rare earth elements (LREE) enrichment, Sr and Pb positive and Nb–Ta–Ti negative
anomalies. However, paleogeographic constraints suggest that the SCS was located far from subduction
zones, so these geochemical signatures could be better explained by a recycling of continental crustal
components within the mantle. The most primitive SCS gabbros expand the Sr–Nd isotopic compositional
range of the Variscan basic magmatism in the Central Iberian Zone to more depleted values. This reflects a
heterogeneous sub-continental lithospheric mantle under central Spain ranging from a depleted mantle
(εNd=+3.1, 87Sr/86Sr=0.704) towards an isotopically enriched component (εNd=−1.6, 87Sr/
86Sr=0.706). Geochemical modelling suggests that mantle enrichment could be explained by minor lower
crustal metapelitic granulite contamination (~2%). Additionally, the Sr–Nd–Pb isotopic ratios of the most
primitive gabbros match the composition of the European subcontinental lithospheric mantle recorded in
ultramafic xenoliths from western and central Europe
Hercynian gabbroic intrusions from the Spanish Central System: Constraints on mantle composition under central Spain
Depto. de Mineralogía y PetrologíaFac. de Ciencias GeológicasTRUEpu
Resilience in Sports: Sport Type, Gender, Age and Sport Level Differences.
There seems to be a broad consensus that there is a positive correlation between resilience and sport performance. However, different studies show divergent results on the role played by certain variables in this relationship. This study aimed to analyze the possible relationships between resilience levels and the practiced sport according to gender, age, and competitive level of the athletes in 1047 competitive athletes from five different sports (handball, basketball, volleyball, athletics, and judo). Resilience was assessed with the Spanish version of the Brief Resilience Scale (BRS). Results of independent samples t-tests or analysis of variance (ANOVA) showed no significant differences on the level of resilience according to the practiced sport or the competitive level. However, the analyses of covariance (ANCOVA) showed that they were related to the gender and age of the athletes, being higher in males than in females, and there was a positive correlation with age. These results seem to suggest the convenience of using differentiated strategies, according to gender and age, when working on all those protective factors that could allow the athlete to perform better when facing adversity in the competitive environmentpost-print384 K
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