177 research outputs found
Nobleza y poder en la Cataluña de la época moderna: una aproximación biográfica al primer marqués de Castelldosrius (1651-1710)
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Nobleza y poder en la Cataluña de la época moderna: una aproximación biográfica al primer marqués de Castelldosrius (1651-1710)
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Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent
Deposition of SiNx : H thin films by the electron cyclotron resonance and its application to Al/SiNx : H/Si structures
We have analyzed the electrical properties and bonding characteristics of SiNx:H thin films deposited at 200 degrees C by the electron cyclotron resonance plasma method. The films show the presence of hydrogen bonded to silicon (at the films with the ratio N/Si<1.33) or to nitrogen (for films where the ratio N/Si is higher than 1.33). In the films with the N/Si ratio of 1.38, the hydrogen content is 6 at. %. For compositions which are comprised of between N/Si=1.1 and 1.4, hydrogen concentration remains below 10 at. %. The films with N/Si=1.38 exhibited the better values of the electrical properties (resistivity, 6x10(13) Omega cm; and electric breakdown field, 3 MV/cm). We have used these films to make metal-insulator-semiconductor (MIS) devices on n-type silicon wafers. C-V measurements accomplished on the structures indicate that the interface trap density is kept in the range (3 - 5) x 10(11) cm(-2) eV(-1) for films with the N/Si ratio below 1.38. For films where the N/Si ratio is higher than 1.3, the trap density suddenly increases, following the same trend of the concentration of N-H bonds in the SiNx:H films. The results are explained on the basis of the model recently reported by Lucovsky [J. Vac. Sci. Technol. B 14, 2832 (1996)] for the electrical behavior of (oxide-nitride-oxide)/Si structures. The model is additionally supported by deep level transient spectroscopy measurements, that show the presence of silicon dangling bonds at the insulator/semiconductor interface (the so-called P-bN0 center), The concentration of these centers follows the same trend with the film composition of the interface trap density and, as a consequence, with the concentration of N-H bonds. This result further supports the N-H bonds located at the insulator/semiconductor interface which act as a precursor site to the defect generation of the type . Si=Si-3, i.e., the P-bN0 centers. A close relation between interface trap density, P-bN0 centers and N-H bond density is established
Decreased resistin expression in mice with different sensitivities to a high-fat diet
The regulation of resistin, a new adipose-derived circulating factor, is the subject of controversy. In particular, the question of its modulation in obesity led to opposite results reported by two different groups. In the current study, we assayed adipocyte resistin mRNA using fluorescent real-time RT-PCR. We studied the expression of resistin in mice which are differently sensitive to diet-induced obesity: the FVB/n strain, which poorly responds to high-fat diet and transgenic mice that express human alpha 2A-AR in adipose tissue in the absence of beta 3-adrenergic receptor (AR) under the FVB genetic background which are highly sensitive to high-fat diet and develop hyperplastic obesity. We observed that FVB mice, which have no significant increased body weight after an 8-week high-fat diet period, exhibited no alteration of resistin expression. In contrast, the transgenic mice developing high-fat diet-induced obesity exhibited markedly downregulated adipocyte resistin mRNA. We also showed that obesity induced by gold thioglucose injection in FVB/n mice reduces the expression of resistin in isolated adipocytes. This argues for decreased expression of resistin as a hallmark of obesity. Moreover, our data show that feeding a high-fat diet is not a primary determinant of resistin regulation
Deposition of SiNx:H thin films by the electron cyclotron resonance and its application to Al/SiNx:H/Si structures
ACME Stellar Spectra. I. Absolutely Calibrated, Mostly Empirical Flux Densities of 55 Cancri and its Transiting Planet 55 Cancri e
The ACME Spectra project provides absolutely calibrated, mostly empirical
spectra of exoplanet host stars for use in analysis of the stars and their
planets. Spectra are obtained from ground-based telescopes and are tied
directly to calibrated ground- and space-based photometry. The spectra remain
only "mostly" empirical because of telluric absorption, but interpolation of
stellar models over the gaps in wavelength coverage provides continuous stellar
spectra. Among other uses, the spectra are suitable for precisely converting
observed secondary eclipses (occultations) into absolute flux units with
minimal recourse to models. In this letter I introduce ACME's methods and
present a calibrated spectrum of the nearby, super-Earth hosting star 55 Cancri
that spans the range from 0.81-5.05 micron. This spectrum is well-suited for
interpreting near- and thermal-infrared eclipse observations. With this
spectrum I show that the brightness temperature of the small, low-mass
transiting planet 55 Cnc e is 1950 +260/-190 K at 4.5 micron (cooler than
previously reported), which corresponds to a planetary flux of 0.44 +0.12/-0.08
mJy. This result suggests the planet has some combination of a nonzero albedo,
a moderately efficient redistribution of absorbed stellar irradiation, and/or
an optically thick atmosphere, but more precise eclipse measurements are
required to distinguish between these scenarii.Comment: Accepted to A&A. 6 pages, 1 figure, 1 electronic table. See
http://irtfweb.ifa.hawaii.edu/~spex/IRTF_Spectral_Library/ for an alternative
spectru
Human alpha 2A-adrenergic receptor gene expressed in transgenic mouse adipose tissue under the control of its regulatory elements.
Catecholamines regulate white adipose tissue function and development by acting through beta- and alpha2-adrenergic receptors (ARs). Human adipocytes express mainly alpha 2A- but few or no beta 3-ARs while the reverse is true for rodent adipocytes. Our aim was to generate a mouse model with a human-like alpha2/beta-adrenergic balance in adipose tissue by creating transgenic mice harbouring the human alpha 2A-AR gene under the control of its own regulatory elements in a combined mouse beta 3-AR-/- and human beta 3-AR+/+ background. Transgenic mice exhibit functional human alpha 2A-ARs only in white fat cells. Interestingly, as in humans, subcutaneous adipocytes expressed higher levels of alpha2-AR than perigonadal fat cells, which are associated with a better antilipolytic response to epinephrine. High-fat-diet-induced obesity was observed in transgenic mice in the absence of fat cell size modifications. In addition, analysis of gene expression related to lipid metabolism in isolated adipocytes suggested reduced lipid mobilization and no changes in lipid storage capacity of transgenic mice fed a high-fat diet. Finally, the development of adipose tissue in these mice was not associated with significant modifications of glucose and insulin blood levels. Thus, these transgenic mice constitute an original model of diet-induced obesity for in vivo physiological and pharmacological studies with respect to the alpha2/beta-AR balance in adipose tissue
Possible Disintegrating Short-Period Super-Mercury Orbiting KIC 12557548
We report here on the discovery of stellar occultations, observed with
Kepler, that recur periodically at 15.685 hour intervals, but which vary in
depth from a maximum of 1.3% to a minimum that can be less than 0.2%. The star
that is apparently being occulted is KIC 12557548, a K dwarf with T_eff = 4400
K and V = 16. Because the eclipse depths are highly variable, they cannot be
due solely to transits of a single planet with a fixed size. We discuss but
dismiss a scenario involving a binary giant planet whose mutual orbit plane
precesses, bringing one of the planets into and out of a grazing transit. We
also briefly consider an eclipsing binary, that either orbits KIC 12557548 in a
hierarchical triple configuration or is nearby on the sky, but we find such a
scenario inadequate to reproduce the observations. We come down in favor of an
explanation that involves macroscopic particles escaping the atmosphere of a
slowly disintegrating planet not much larger than Mercury. The particles could
take the form of micron-sized pyroxene or aluminum oxide dust grains. The
planetary surface is hot enough to sublimate and create a high-Z atmosphere;
this atmosphere may be loaded with dust via cloud condensation or explosive
volcanism. Atmospheric gas escapes the planet via a Parker-type thermal wind,
dragging dust grains with it. We infer a mass loss rate from the observations
of order 1 M_E/Gyr, with a dust-to-gas ratio possibly of order unity. For our
fiducial 0.1 M_E planet, the evaporation timescale may be ~0.2 Gyr. Smaller
mass planets are disfavored because they evaporate still more quickly, as are
larger mass planets because they have surface gravities too strong to sustain
outflows with the requisite mass-loss rates. The occultation profile evinces an
ingress-egress asymmetry that could reflect a comet-like dust tail trailing the
planet; we present simulations of such a tail.Comment: 14 pages, 7 figures; submitted to ApJ, January 10, 2012; accepted
March 21, 201
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