Simultaneous Grafting of Poly(Acrylic Acid) and Poly(Ethylene Glycol) onto Chitosan using Gamma Radiation: Polymer Networks for Removal of Textile Dyes

Chitosan is a bio-based polyelectrolyte with high potential for wastewater treatment. Chitosan can remove anionic dyes by adsorption but it has low performance in the removal of cationic dyes. In this work, we report the synthesis of chitosan-based graft-copolymers using gamma radiation. Acrylic acid and poly(ethylene glycol) were grafted successfully onto chitosan applying a radiation dose of 12 kGy at a dose rate of 8 kGyh-1. The grafted-copolymers have improved adsorptive properties for the removal of basic dyes reaching a maximum adsorption capacity higher than 300 mgg-1. The Lanmguir’s isotherm model described satisfactorily the interaction between the grafted copolymers and basic dyes. Freundlich’s isotherm model described the adsorption of anionic dye acid orange 52. The grafted copolymers removed successfully textile dyes from wastewater of the dyeing process. The best results were obtained in the removal of direct and basic dyes. Further, poly(ethylene glycol) grafted on the copolymer conferred better swelling behavior making easy the separation of the adsorbent after dye removal. The results showed that the adsorbent materials synthesized by radiochemical graftcopolymerization are more efficient than the beads, composite materials, and blends of chitosan

Modelling ground rupture due to groundwater withdrawal: applications to test cases in China and Mexico

Abstract. The stress variation induced by aquifer overdraft in sedimentary basins with shallow bedrock may cause rupture in the form of pre-existing fault activation or earth fissure generation. The process is causing major detrimental effects on a many areas in China and Mexico. Ruptures yield discontinuity in both displacement and stress field that classic continuous finite element (FE) models cannot address. Interface finite elements (IE), typically used in contact mechanics, may be of great help and are implemented herein to simulate the fault geomechanical behaviour. Two main approaches, i.e. Penalty and Lagrangian, are developed to enforce the contact condition on the element interface. The incorporation of IE incorporation into a three-dimensional (3-D) FE geomechanical simulator shows that the Lagrangian approach is numerically more robust and stable than the Penalty, thus providing more reliable solutions. Furthermore, the use of a Newton-Raphson scheme to deal with the non-linear elasto-plastic fault behaviour allows for quadratic convergence. The FE – IE model is applied to investigate the likely ground rupture in realistic 3-D geologic settings. The case studies are representative of the City of Wuxi in the Jiangsu Province (China), and of the City of Queretaro, Mexico, where significant land subsidence has been accompanied by the generation of several earth fissures jeopardizing the stability and integrity of the overland structures and infrastructure.</p

Holocene paleo-earthquakes recorded at the transfer zone of two majorfaults: the Pastores and Venta de Bravo fault (Trans-Mexican Volcanic Belt).

We present evidence of fi ve late Holocene earthquake ruptures observed at two paleoseismological trenches in the Laguna Bañí sag pond (Trans-Mexican Volcanic Belt, central Mexico). The trenches exposed two fault branches of the western termination of the Pastores fault, one of the major fault systems within the central Trans-Mexican Volcanic Belt. The site was studied by combining geomorphological and structural approaches, volcanic mapping, ground-penetrating radar, and paleoseismological analysis. The study revealed that coseismic surface rupture was noncharacteristic, and that the exposed fault branches had not always moved simultaneously. The fault tip has ruptured at least 5 times within the past 4 k.y., and the rupture events followed and preceded the deposition of an ignimbrite. The close temporal relationship of the seismic rupture with the volcanic activity of the area could be the result of volcanism triggered by faulting and its associated seismicity. The relatively high recurrence of seismic events (1.1 2.6 k.y.) and the noncharacteristic fault behavior observed at this tip of the Pastores fault suggest that the fault might have been active as a primary fault rupturing along segments of variable length or depth, and/or that the fault ruptured eventually as a secondary fault. The secondary ruptures would likely be related to earthquakes produced at major neighboring faults such as the Acambay fault, which moved during the 1912 Acambay earthquake, or the Venta de Bravo fault. A relatively large slip rate estimated for this fault branch (0.23 0.37 mm/yr) leads us to contemplate the possible connection at depth between the Pastores and the Venta de Bravo faults, increasing the maximum expected magnitude for central Mexico

Contrast of a Quality Control Model for Sustainability in a Mexican Organization in Central Mexico

Often, the total quality has been instrumented before being weighted. The strategies even precede a diagnosis in Mexican organizations, but in an opposite sense, the present work set out to establish the reliability and validity of an instrument to measure the perception of total quality based on three indicators related to management. , production and transfer of knowledge. A nonperimental study was carried out with a non-probabilistic selection of 124 administrative staff and employees from an organization in central Mexico. From a structural model ⌠X2 = 123,24 (23df) p = 0,010; GFI = 0,990; CFI =,991; IFI = 0,993; RMSEA = 0,007⌡, it was found that management affects production (0,38) and this about the total perceived quality (0,35), although there are lines of research concerning empathy, commitment, entrepreneurship, satisfaction and happiness in relation to the implementation of continuous improvements to the quality of processes and products

Image-based Analysis of Patterns Formed in Drying Drops

Image processing and pattern recognition offer a useful and versatile method for optically characterizing drops of a colloidal solution during the drying process and in its final state. This paper exploits image processing techniques applied to cross-polarizing microscopy to probe birefringence and the bright-field microscopy to examine the morphological patterns. The bio-colloidal solution of interest is a mixture of water, liquid crystal (LC) and three different proteins [lysozyme (Lys), myoglobin (Myo), and bovine serum albumin (BSA)], all at a fixed relative concentration. During the drying process, the LC phase separates and becomes optically active detectable through its birefringence. Further, as the protein concentrates, it forms cracks under strain due to the evaporation of water. The mean intensity profile of the drying process is examined using an automated image processing technique that reveals three unique regimes: a steady upsurge, a speedy rise, and an eventual saturation. The high values of standard deviation show the complexity, the roughness, and inhomogeneity of the image surface. A semi-automated image processing technique is proposed to quantify the distance between the consecutive cracks by converting those into high contrast images. The outcome of the image analysis correlates with the initial state of the mixture, the nature of the proteins, and the mechanical response of the final patterns. The paper reveals new insights on the self-assembly of the macromolecules during the drying mechanism of any aqueous solution

Modelo de los determinantes de la actitud hacia la rehidratación

Las políticas de salud suponen que el factor clave de sus programas preventivos está en la participación de la gente respecto a su rehidratación, porque esta se considera un instrumento de prevención de las enfermedades crónicas degenerativas, que han incrementado su tasa de morbilidad recientemente. En tal sentido, el objetivo del presente trabajo es establecer un modelo de las relaciones causales entre factores sociodemográficos y cognitivos relativos al consumo de bebidas. Para tal propósito, se llevó a cabo un estudio transversal y correlacional con una muestra de 100 afiliados a un hospital público. A partir de un modelo estructural (X2 = 163.873, 28 gl, p = .000; GFI = .875; AGFI = .840; PGF = .681; RMSEA = .027; RMR = .066), se estableció que la edad determinó negativamente la actitud hacia la rehidratación (β = -.22) mientras que las creencias de rehidratación grupal (CRG) incidieron de manera positiva (β= ,47.). En el marco de las teorías actitudinales, se discutió la inclusión de las normas y percepciones como sus determinantes

Gliomas and Farm Pesticide Exposure in Women: The Upper Midwest Health Study

An excess incidence of brain cancer in male farmers has been noted in several studies, but few studies have focused on women. The National Institute for Occupational Safety and Health Upper Midwest Health Study evaluated effects of rural exposures for 341 female glioma cases and 528 controls, all adult (18–80 years of age) nonmetropolitan residents of Iowa, Michigan, Minnesota, and Wisconsin. On average, controls lived longer on farms than did cases. After adjusting for age, age group, education, and farm residence, no association with glioma was observed for exposure to arsenicals, benzoic acids, carbamates, chloroacetanilides, dinitroanilines, inorganics, organochlorines, organophosphates, phenoxys, triazines, or urea-based or estrogenic pesticides. An increased risk of glioma was observed for carbamate herbicides but was not statistically significant (odds ratio = 3.0; 95% confidence interval, 0.9–9.5). No association was observed between glioma and exposure to 12 widely used specific pesticides, after adjustment for age, age group, education, and any other pesticide exposure. These results were not affected after exclusion of proxy respondents (43% of cases, 2% of controls). Women were less likely than men to have applied pesticides, but more likely to have laundered pesticide-contaminated clothes. Storing pesticides in the house was associated with a statistically non-significant increased risk. Results show that exposure to pesticides was not associated with an increased risk of intracranial gliomas in women. Other farm-related factors could be etiologic factors and will be discussed in future reports

Application of Optimum Compaction Energy in the Development of Bricks Made with Construction Trash Soils

In general, bricks frequently show different densities and therefore different resistances because the compaction energy is not considered in their production. Expansive soils represent a problem for light buildings over them because of volumetric instability. A generalized solution has been to extract them and substitute them by inert soil; thus they become construction trash. So, in this work the compaction energy aspect and the use of construction trash soils in the elaboration of resistant masonry bricks of homogeneous and controlled density are a new contribution in the production of bricks of better quality. First, the soil was stabilized with CaOH which leads to a decrease in its volumetric changes. Then, they were compacted with a specific energy for obtaining an optimal and maximum controlled density to ensure an increase in strength. Our results show that two optimal compaction energies can be considered with respect to the variation of optimum moisture in masonry bricks of expansive soil stabilized with lime. The first is when the optimal humidity reaches its smallest value (integrated soil lumps) and the second is when humidity increases (disintegrated soil lumps), after reaching its lowest value. We also conclude that high compaction energy does not improve density values

Calculation of the efficacy of vaccines against tick infestations on cattle

Articles in International JournalsCattle ticks are responsible for great economic losses in cattle farming worldwide, and their main control method, chemicals, has been showing problems, whether resulting from the development of resistant strains of ticks or environmental contamination. Research studies directed toward developing vaccines against ticks are emerging. One way to evaluate those vaccines is to calculate the percentage of efficacy. The aim of this study was to analyze scientific publications archived in PubMed that used this method of assessment and discuss the main factors that may affect its calculation. Thus, 25 articles addressing this subject were selected. The percentage of efficacy was usually calculated in one of two ways, with one considering the reduced fertility of eggs and the other not. The latter method may underestimate the vaccine efficacy, and the most complete formula for calculating the efficacy reflects how much the vaccine actually affects the infestation. In our view, the use of the complete formula for calculating the percentage of efficacy is broader and more representative of the vaccine effect on the tick population.RESUMO - Carrapatos de bovinos são responsáveis por grandes perdas econômicas para a pecuária bovina mundial e seu principal método de controle, o químico, vem apresentando problemas, seja pelo desenvolvimento de amostras de carrapatos resistentes ou pela contaminação ambiental. Na tentativa de diminuir a utilização dos acaricidas, surgem pesquisas direcionadas ao desenvolvimento de vacinas contra carrapatos. Uma maneira de avaliar essas vacinas é pelo cálculo de percentagem de eficácia. O objetivo deste trabalho foi analisar as publicações científicas indexadas no PubMed que utilizaram este método de avaliação e discutir os principais fatores que podem interferir no seu cálculo. Dessa maneira, selecionaram-se 25 artigos que tratavam desse assunto. A percentagem de eficácia apareceu sendo calculada de duas formas, uma considerando a redução da fertilidade dos ovos e a outra não. Essa última pode subestimar a eficiência da vacina, e a fórmula de cálculo da eficácia mais completa representa o quanto da infestação a vacina realmente reduziu. Em nosso entendimento, a utilização da fórmula completa para o cálculo da percentagem de eficácia é mais abrangente e representativa do efeito da vacina na população de carrapatos

Anticancer potential of Thevetia peruviana fruit methanolic extract

Abstract Background: Thevetia peruviana (Pers.) K. Schum or Cascabela peruviana (L.) Lippold (commonly known as ayoyote, codo de fraile, lucky nut, or yellow oleander), native to Mexico and Central America, is a medicinal plant used traditionally to cure diseases like ulcers, scabies, hemorrhoids and dissolve tumors. The purpose of this study was to evaluate the cytotoxic, antiproliferative and apoptotic activity of methanolic extract of T. peruviana fruits on human cancer cell lines. Methods: The cytotoxic activity of T. peruviana methanolic extract was carried out on human breast, colorectal, prostate and lung cancer cell lines and non-tumorigenic control cells (fibroblast and Vero), using the MTT assay. For proliferation and motility, clonogenic and wound-healing assays were performed. Morphological alterations were monitored by trypan blue exclusion, as well as DNA fragmentation and AO/EB double staining was performed to evaluate apoptosis. The extract was separated using flash chromatography, and the resulting fractions were evaluated on colorectal cancer cells for their cytotoxic activity. The active fractions were further analyzed through mass spectrometry. Results: The T. peruviana methanolic extract exhibited cytotoxic activity on four human cancer cell lines: prostate, breast, colorectal and lung, with values of IC50 1.91 ± 0.76, 5.78 ± 2.12, 6.30 ± 4.45 and 12.04 ± 3.43 μg/mL, respectively. The extract caused a significant reduction of cell motility and colony formation on all evaluated cancer cell lines. In addition, morphological examination displayed cell size reduction, membrane blebbing and detachment of cells, compared to non-treated cancer cell lines. The T. peruviana extract induced apoptotic cell death, which was confirmed by DNA fragmentation and AO/EB double staining. Fractions 4 and 5 showed the most effective cytotoxic activity and their MS analysis revealed the presence of the secondary metabolites: thevetiaflavone and cardiac glycosides. Conclusion: T. peruviana extract has potential as natural anti-cancer product with critical effects in the proliferation, motility, and adhesion of human breast and colorectal cancer cells, and apoptosis induction in human prostate and lung cancer cell lines, with minimal effects on non-tumorigenic cell lines. Keywords: Cytotoxic activity, Anti-proliferative activity, Motility, Apoptosis, Human cancer cells, Flavonoid, Cardiac glycoside