Guía de apoyo y orientación para padres de niños con discapacidad visual

Esta guía tiene la finalidad de ayudar a los padres de los niños con discapacidad visual a alcanzar el desarrollo armónico de sus hijos. A través de las diferentes actividades que propone quiere potenciar la relación padres-hijos, pero sobretodo, aspira que el niño con discapacidad visual alcance un desarrollo pleno de sus capacidades, logrando con ello una vida normal

A General Asymmetric Formal Synthesis of Aza-Baylis–Hillman Type Products under Bifunctional Catalysis

This is the peer reviewed version of the following article: Chemistry A European Journal 24.13 (2018): 3117-3121, which has been published in final form at https://doi.org/10.1002/chem.201705218. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived VersionsWeinheim A new organocatalytic strategy for the synthesis of enantioenriched aza-Baylis–Hillman type products via a frustrated vinylogous reaction is presented. This process proceeds under mild conditions with good yields, completed Z/E selectivity and excellent enantioselectivities. Moreover, easy derivatizations of the final products led to important building blocks of organic synthesis such as 1,3-aminoalcohols and Lewis base catalystsFinancial support from the Spanish Government (CTQ2015-64561-R), the European Research Council (ERC-CG, contract number: 647550), is also gratefully acknowledge

Comorbilidad entre trastornos de conducta y depresión mayor en la adolescencia: prevalencia, teorías explicativas y estatus nosológico

This theoretical study examines the main findings and researches regarding the comorbidity between conduct disorder and major depression in adolescence. On the one hand, it is argued that high prevalence of comorbidity imply common risk factors (biological, cognitive- emotional and socio-cultural) and a causal relationship between these mental illness, usually conduct disorder preceding major depression. On the other hand, independent nosological status of this comorbidity» is advocated on the basis of several external criteria (e.g. response to treatment, course into adulthood and psychopathological profile), which distinguish this mixed clinical entity from conduct disorder and major depression, especially the latter category. These findings are discussed concerning the classification of «depressive conduct disorder» within current diagnosis reference manuals

COVID-19 and menstrual-related disturbances: a Spanish retrospective observational study in formerly menstruating women

IntroductionFour years after the start of the pandemic, there is limited evidence on the impact of COVID-19 on the women's health regardless of their reproductive status.ObjectiveThe aim was to analyze the prevalence and associated factors of menstrual-related disturbances in formerly menstruating women following SARS-CoV-2 infection.Study designA retrospective observational study of adult women in Spain was conducted during the month of December 2021 using an online survey (N = 17,512). The present analysis includes a subpopulation of SARS-CoV-2-infected and formerly menstruating women (n = 72). The collected data included general characteristics, medical history, and specific information on COVID-19. Chi-square and Mann-Whitney U-tests were performed. Bivariate logistic regression analysis was then performed to investigate possible associations between the occurrence of menstrual-related disturbances after SARS-CoV-2 infection.Results38.8% of participants experienced menstrual-related disturbances following COVID-19. Among these, unexpected vaginal bleeding (20.8%) was the most common event, followed by spotting (11.1%) ( Table 1). Other reported changes were in the length (shorter = 12.5%) and flow (heavier = 30.3%) of menstrual bleeding in comparison to their previous experience. Regression analysis revealed that being a perimenopausal woman [adjusted odds ratio (AOR) 4.721, CI 95%, 1.022–21.796, p = 0.047] and having a previous diagnosis of menorrhagia (AOR 5.824 CI 95%, 1.521–22.310, p = 0.010) were factors associated with the event.ConclusionThese findings could help health professionals provide their patients with up-to-date scientific information to empower them to actively manage their reproductive health, especially in societies where menstrual health is still taboo

Influence of initial chemical composition and characteristics of pulps on the production and properties of lignocellulosic nanofibers

This work aimed to study the influence of the initial chemical composition (glucans, lignin, xylan, and mannans), intrinsic viscosity, and carboxylate groups of pulps on the production process and final properties of lignocellulosic nanofibers (LCNF). Pulps of pine sawdust, eucalyptus sawdust, and sugarcane bagasse subjected to conventional pulping and highly oxidized processes were the starting materials. The LCNF were obtained by TEMPO mediated oxidation and mechanical fibrillation with a colloidal grinder. The nanofibrillation degree, chemical charge content, rheology, laser profilometry, cristallinity and atomic force microscopy were used to characterize the LCNF. The carboxylate groups, hemicelluloses and lignin of the initial pulps were important factors that affected the production process of LCNF. The results revealed that intrinsic viscosity and carboxylate groups of the initial pulps affected LCNF production process, whereas lignin and hemicelluloses influenced the viscosity of LCNF aqueous suspensions, the roughness of LCNF films, and the carboxylate groups content of LCNF.Fil: Ehman, Nanci Vanesa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Materiales de Misiones. Universidad Nacional de Misiones. Facultad de Ciencias Exactas Químicas y Naturales. Instituto de Materiales de Misiones; ArgentinaFil: Lourenço, Ana Filipa. Universidad de Coimbra; PortugalFil: McDonagh, Birgitte Hjelmeland. Rise, Paper And Fibre Research; NoruegaFil: Vallejos, María Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Materiales de Misiones. Universidad Nacional de Misiones. Facultad de Ciencias Exactas Químicas y Naturales. Instituto de Materiales de Misiones; ArgentinaFil: Felissia, Fernando Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Materiales de Misiones. Universidad Nacional de Misiones. Facultad de Ciencias Exactas Químicas y Naturales. Instituto de Materiales de Misiones; ArgentinaFil: Ferreira, Paulo Jorge Tavares. Universidad de Coimbra; PortugalFil: Chinga Carrasco, Gary. Rise, Paper And Fibre Research; NoruegaFil: Area, Maria Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Materiales de Misiones. Universidad Nacional de Misiones. Facultad de Ciencias Exactas Químicas y Naturales. Instituto de Materiales de Misiones; Argentin

A new set of estimated cardiorespiratory fitness equations are associated with cognitive performance in older adults

This study aimed to develop new equations to estimate cardiorespiratory fitness specifically for older adults and, secondly, to analyze the associations of cardiorespiratory fitness, both objectively measured and estimated using new equations, with cognitive performance. Ninety-two older adults (41 females, 65-75years) from baseline data of a randomized controlled trial were analyzed ("ClinicalTrials.gov" Identifier: NCT03923712). Participants completed 4 measurement sessions including (i) physiological and health indicators in a laboratory setting, (ii) field-based fitness tests, (iii) sociodemographic and physical activity questionnaires, and (iv) a battery of neuropsychological tests to evaluate cognitive performance. The main findings were as follows: (i) a set of new equations with good predictive value for estimated cardiorespiratory fitness were developed (74-87%), using different scenarios of complexity and/or equipment requirements, and (ii) higher estimated cardiorespiratory fitness, even using its simplest equation (eCRF=-1261.99+1.97*6min walking test (m)+1.12*bioimpedance basal metabolic rate (kcal/day)+5.25*basal heart rate (bpm)), was associated with better cognitive performance evaluated by several neuropsychological tests (i.e., language, cognitive flexibility, fluency, attention, and working memory), similar to using objectively measured cardiorespiratory fitness. In summary, a new set of estimated cardiorespiratory fitness equations have been developed with predictive values ranging from 74 to 87% that could be used based on necessity, availability of equipment, resources, or measurement context. Moreover, similar to objectively measured cardiorespiratory fitness, this measure of estimated cardiorespiratory fitness was positively associated with performance on language, fluency, cognitive flexibility, attention, and working memory, independently of sex, age, and education level. © 2023. The Author(s)

¿Son rentables las empresas concentradas? El caso del sector de curtido de pieles en el Ecuador

El presente trabajo de investigación identifica la estructura de mercado del sector Curtido y Adobo de Pieles en el Ecuador CIIU: C151101 y tiene como objetivo establecer la relación entre rentabilidad, costos y concentración de mercado. Se calculó el índice de Herfindhal-Hirshman utilizado para casos de estructura de mercado imperfecta; y por otro lado, los índices de solvencia, liquidez, rentabilidad, para evaluar el desempeño financiero de las empresas concentradas. Además, se diseñaron cuatro modelos econométricos a los cuales se aplicaron pruebas estadísticas de idoneidad de los estimadores. Se aplicó análisis de regresión lineal simple y múltiple en varias experimentaciones a través de Mínimos cuadrados Ordinarios. De las nueve empresas del oligopolio, se identificaron cuatro empresas concentradas que controlan el 73,12% del mercado, con un margen de rentabilidad del 0,1391 promedio del oligopolio para el período de estudio 2011-2015. De los modelos econométricos desarrollados uno permitió evidenciar a través de la prueba estadística de Fisher que la concentración de mercado y los costos de producción inciden en la rentabilidad con un p-value de 0,00035, es decir, existe una relación lineal significativa de la rentabilidad del oligopolio con los costos de producción y la concentración del mercado, demostrándose así que este grupo de empresas obtienen beneficios por efecto de su capacidad para concentrar el mercado.// The present research identifies the market structure of the Tanning and Leather Sector in Ecuador ISIC: C151101and aims to establish the relation between profitability, costs and market concentration. The Herfindhal-Hirshman index used for cases of imperfect market structure has been calculated; and on the other hand, the solvency, liquidity and profitability to evaluate the financial performance of the concentrated companies. Additionally, four econometric models have been designed to which statistical tests of adecquacy have been applied. Simple and multiple linear regression analysis has been applied in several experiments through Ordinary Least Squares. Of the nine oligopoly companies, four companies have been identified that control 73,12% of the market, with a margin of return of 0,1391 average of the oligopoly for the period of study 2011-2015. One of the developed econometric models has made possible to show through Fisher’s statistical test that market concentration and production costs have an effect on profitability with a p-value of 0.00035, meaning that there is a significant linear relation of the oligopoly with cost production and market concentration, demonstrating that this group of companies makes profits because of their ability to concentrate the market