337 research outputs found

    Senior Recital: Lara Carr, piano

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    Kennesaw State University School of Music presents Senior Recital: Lara Carr, piano.https://digitalcommons.kennesaw.edu/musicprograms/1723/thumbnail.jp

    Senior Recital: Lara Carr, soprano

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    Kennesaw State University School of Music presents Senior Recital: Lara Carr, soprano.https://digitalcommons.kennesaw.edu/musicprograms/1724/thumbnail.jp

    The "Lactation After Infant Death (AID) Framework": A Guide for Online Health Information Provision About Lactation After Stillbirth and Infant Death

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    Most parents who give birth to a stillborn infant, or who give birth then endure the death of their young infant, will encounter the onset of lactation (McGuinness et al., 2014). For breastfeeding parents who experience the death of their older infant, many will have established lactation or frozen stores of expressed human milk ([EHM] McGuinness et al., 2014). Despite this, lactation and EHM are rarely discussed with bereaved parents in healthcare settings (Britz & Henry, 2013; Carroll, Lenne, McEgan et al., 2014; Redshaw et al., 2014). As a result, many bereaved parents who have recently given birth are unprepared when they begin to lactate, and few are aware of the range of suppression, expression, or donation options that may be available to them (Carroll & Lenne, 2019; McGuinness et al., 2014; Welborn, 2012b). The lack of anticipatory guidance regarding lactation after infant death can be a significant source of distress for parents, exacerbating the emotional pain of their child’s death (Carroll & Lenne, 2019; McGuinness et al., 2014; Welborn, 2012b). This lack may also inadvertently compound the invisibility and ambiguity of parenthood experienced by many bereaved parents (Cacciatore et al., 2008; Layne, 2003; Oreg, 2019). Furthermore, parents bereaved as a result of giving birth to a stillborn infant or enduring their infant’s death are likely to experience breast engorgement, pain, and milk leakage (McGuinness et al., 2014) and, in the absence of reliable information, they may follow lactation management methods that prove ineffective or lead to mastitis or abscess. To prevent adverse outcomes, bereaved parents require anticipatory guidance or lactation support from qualified health professionals.This research is funded by an Australian Research Council Discovery Project (DP180100517)

    Structurally Dependent Fano Resonances in the Infrared Spectra of Phonons in Few-Layer Graphene

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    The in-plane optical phonons around 200 meV in few-layer graphene are investigated utilizing infrared absorption spectroscopy. The phonon spectra exhibit unusual asymmetric features characteristic of Fano resonances, which depend critically on the layer thickness and stacking order of the sample. The phonon intensities in samples with rhombohedral (ABC) stacking are significantly higher than those with Bernal (AB) stacking. These observations reflect the strong coupling between phonons and interband electronic transitions in these systems and the distinctive variation in the joint density of electronic states in samples of differing thickness and stacking order.Comment: 20 pages, 7 figures, supplementary material include

    The <i>Castalia</i> mission to Main Belt Comet 133P/Elst-Pizarro

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    We describe Castalia, a proposed mission to rendezvous with a Main Belt Comet (MBC), 133P/Elst-Pizarro. MBCs are a recently discovered population of apparently icy bodies within the main asteroid belt between Mars and Jupiter, which may represent the remnants of the population which supplied the early Earth with water. Castalia will perform the first exploration of this population by characterising 133P in detail, solving the puzzle of the MBC’s activity, and making the first in situ measurements of water in the asteroid belt. In many ways a successor to ESA’s highly successful Rosetta mission, Castalia will allow direct comparison between very different classes of comet, including measuring critical isotope ratios, plasma and dust properties. It will also feature the first radar system to visit a minor body, mapping the ice in the interior. Castalia was proposed, in slightly different versions, to the ESA M4 and M5 calls within the Cosmic Vision programme. We describe the science motivation for the mission, the measurements required to achieve the scientific goals, and the proposed instrument payload and spacecraft to achieve these

    Reversal of diabetic-induced myopathy by swimming exercise in pregnant rats:a translational intervention study

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    Gestational diabetes mellitus (GDM) plus rectus abdominis muscle (RAM) myopathy predicts long-term urinary incontinence (UI). Atrophic and stiff RAM are characteristics of diabetes-induced myopathy (DiM) in pregnant rats. This study aimed to determine whether swimming exercise (SE) has a therapeutic effect in mild hyperglycemic pregnant rats model. We hypothesized that SE training might help to reverse RAM DiM. Mild hyperglycemic pregnant rats model was obtained by a unique subcutaneous injection of 100 mg/kg streptozotocin (diabetic group) or citrate buffer (non-diabetic group) on the first day of life in Wistar female newborns. At 90 days of life, the rats are mated and randomly allocated to remain sedentary or subjected to a SE protocol. The SE protocol started at gestational day 0 and consisted of 60 min/day for 6 days/week in a period of 20 days in a swim tunnel. On day 21, rats were sacrificed, and RAM was collected and studied by picrosirius red, immunohistochemistry, and transmission electron microscopy. The SE protocol increased the fiber area and diameter, and the slow-twitch and fast-twitch fiber area and diameter in the diabetic exercised group, a finding was also seen in control sedentary animals. There was a decreased type I collagen but not type III collagen area and showed a similar type I/type III ratio compared with the control sedentary group. In conclusion, SE during pregnancy reversed the RAM DiM in pregnant rats. These findings may be a potential protocol to consider in patients with RAM damage caused by GDM

    1873-1874, End of a Century?: Time and Space in Valera's Pepita Jiménez, Ros de Olano's Jornadas de retorno, and Alarcón's El sombrero de tres picos and La Alpujarra

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    This article argues for the existence of a literature of the first Spanish Republic in the early 1870s. Valera's Pepita Jimenez makes sense in relation to this literature, rather than in comparison with 'Realism'. The literature of the first republic is distinguished by two facets: an ongoing dialogue with Ros de Olano's experiments in simultaneous compression and extension of form; and a belief that the nineteenth-century revolutionary spirit of the age has reached a critical end point, and needs reinvention that leads to Restoration politics

    A Bacterial Cytotoxin Identifies the RhoA Exchange Factor Net1 as a Key Effector in the Response to DNA Damage

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    Background: Exposure of adherent cells to DNA damaging agents, such as the bacterial cytolethal distending toxin (CDT) or ionizing radiations (IR), activates the small GTPase RhoA, which promotes the formation of actin stress fibers and delays cell death. The signalling intermediates that regulate RhoA activation and promote cell survival are unknown. Principal Findings: We demonstrate that the nuclear RhoA-specific Guanine nucleotide Exchange Factor (GEF) Net1 becomes dephosphorylated at a critical inhibitory site in cells exposed to CDT or IR. Expression of a dominant negative Net1 or Net1 knock down by iRNA prevented RhoA activation, inhibited the formation of stress fibers, and enhanced cell death, indicating that Net1 activation is required for this RhoA-mediated responses to genotoxic stress. The Net1 and RhoAdependent signals involved activation of the Mitogen-Activated Protein Kinase p38 and its downstream target MAPKactivated protein kinase 2. Significance: Our data highlight the importance of Net1 in controlling RhoA and p38 MAPK mediated cell survival in cells exposed to DNA damaging agents and illustrate a molecular pathway whereby chronic exposure to a bacterial toxin ma
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