117 research outputs found

    La estructura de la dentición caduca de huilatherium pluripicatum, leontiniidae (notoungulata) del mioceno de colombia

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    Este trabajo constituye una contribución al conocimiento de Huilatherium pluriplicatum VILLARROEL and amp; GUERRERO, 1985 Leontíniido del Mioceno de La Venta (Huila, Colombia).  Se describen en detalle los rasgos de los dientes caducos (Iacteales) de sus series dentarias superior e inferior y se las compara con las de la dentición permanente.  A falta de una terminología morfodentaria adecuada a la naturaleza del trabajo, se propone una nueva que se basa en propuestas anteriores.This paper is a contribution to the knowledge of Huilatherium pluriplicatum VILLARROEL and amp; GUERRERO, 1985, Leontiniid of the Miocene of La Venta region (Huila, Colombia). The detailed description of deciduous teeth of both upper and lower dentitions is studied; comparison is made with permanent dentition.  A new more adequate morphodentary terminology is proposed which is based on other former propositions

    Riesgo psicosocial percibido y salud mental en profesores de colegios vulnerables de la Región del Maule

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    87 p.El estudio, de diseño no experimental y corte transversal, tiene como objetivos identificar el nivel de percepción de riesgos psicosociales y la percepción de salud mental y determinar su relación, en los 90 profesores rurales y urbanos de colegios vulnerables de la muestra. Para evaluar los riesgos psicosociales se aplicó el cuestionario SUSESO-ISTAS 21 versión breve, validado en Chile por Alvarado et al. (2012) y para evaluar salud mental se utilizaron las escalas de sintomatología de estrés de Setterlind, Hallman, Burell, Odén y Lisspers (2001) y tres escalas del cuestionario SF-36 de Ware y Sherbourne (1992). Se hizo un análisis descriptivo y correlacional y una comparación de medias de las variables incluidas en esta investigación. Los resultados evidencian un riesgo alto para los factores psicosociales compensaciones y doble presencia, una percepción baja de salud general y una presencia baja de síntomas de estrés. Existe una relación negativa estadísticamente significativa entre exigencias psicológicas con salud mental, vitalidad, síntomas cognitivos y conductuales de estrés; compensaciones con salud mental y síntomas conductuales; doble presencia con salud general, salud mental, vitalidad, síntomas conductuales y cognitivos. Hay medias significativamente mayores para el contexto urbano en trabajo activo y desarrollo de habilidades (U de Mann-Whitney= 492,500; Z=-3,715; p=0,000), apoyo social y calidad de liderazgo (t=-3,291;gl=88;p=0,001) y compensaciones (t=-2,052;gl=88;p=0,043). El contexto rural tiene una media significativamente mayor en la dimensión salud mental (t=2,467;gl=88;p=0,016). A partir de los resultados se discuten las implicancias en el contexto docente y se proponen sugerencias para futuras investigaciones. Palabras clave: docentes, salud mental, factores de riesgos psicosociales,sintomatología de estrés

    La fauna de mamíferos fósiles del pleistoceno de jútua, municipio de soata (boyacá, colombia)

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    En las proximidades del  Núcleo Escolar de Jútua, 6 Km al NNE de Soatá, municipio de Boyacá, se han colectado restos de mamíferos fósiles pleistocénicos. A pesar de que la calidad del material no permite determinaciones seguras a nivel especifico, y en algunos casos ni siquiera a nivel genérico, la colección resulta importante puesto que incluye dos taxones hasta hoy no mencionados en el país: un Caninae indet. y un ?Neochoerus (Hydrochoeridae). Por otra parte, el descubrimiento de la fauna que se describe ha permitido aclarar lo relacionado con la procedencia de los fósiles de Soatá; ahora se sabe que estos provienen de por lo menos dos lugares diferentes: Portugalete y Jútua, ubicados al SSE y NNE, respect iva mente, de Soatá, y están separados entre si por 9 km.In the neighborhoods of the Primary School of Jútua, 6 kms to the NNW from the town of Soatá (Boyacá) have been collected some Pleistocene mammals. In spite of the not so good quality of the fossils, that prevents a clear determination at the species level, even in some cases at genus level, this collection is important, because it includes two taxons not previously reported from Colombia: Caninae indet. and?Neochoerus (Hydrochoeridae).  The discovery of this fauna clarifies the origin of the Soatá fossils; they stem from two different places: Portugalete and Jútua, SSE and NNE from Soatá, respectively, some 9 kms apart

    Natural Variation in Diauxic Shift between Patagonian Saccharomyces eubayanus Strains

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    The study of natural variation can untap novel alleles with immense value for biotechnological applications. Saccharomyces eubayanus Patagonian isolates exhibit differences in the diauxic shift between glucose and maltose, representing a suitable model to study their natural genetic variation for novel strains for brewing. However, little is known about the genetic variants and chromatin regulators responsible for these differences. Here, we show how genome-wide chromatin accessibility and gene expression differences underlie distinct diauxic shift profiles in S. eubayanus. We identified two strains with a rapid diauxic shift between glucose and maltose (CL467.1 and CBS12357) and one strain with a remarkably low fermentation efficiency and longer lag phase during diauxic shift (QC18). This is associated in the QC18 strain with lower transcriptional activity and chromatin accessibility of specific genes of maltose metabolism and higher expression levels of glucose transporters. These differences are governed by the HAP complex, which differentially regulates gene expression depending on the genetic background. We found in the QC18 strain a contrasting phenotype to those phenotypes described in S. cerevisiae, where hap4D, hap5D, and cin5D knockouts significantly improved the QC18 growth rate in the glucose-maltose shift. The most profound effects were found between CIN5 allelic variants, suggesting that Cin5p could strongly activate a repressor of the diauxic shift in the QC18 strain but not necessarily in the other strains. The differences between strains could originate from the tree host from which the strains were obtained, which might determine the sugar source preference and the brewing potential of the strain.Fil: Molinet, Jennifer. Universidad de Santiago de Chile; ChileFil: Eizaguirre, Juan Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto Andino Patagónico de Tecnologías Biológicas y Geoambientales. Universidad Nacional del Comahue. Instituto Andino Patagónico de Tecnologías Biológicas y Geoambientales; ArgentinaFil: Quintrel, Pablo. Universidad de Santiago de Chile; ChileFil: Bellora, Nicolás. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica. Gerencia de Área de Aplicaciones de la Tecnología Nuclear. Instituto de Tecnologías Nucleares para la Salud; ArgentinaFil: Villarroel, Carlos A.. Universidad de Talca; ChileFil: Villarreal, Pablo. Universidad de Santiago de Chile; ChileFil: Benavides Parra, José. Universidad de Santiago de Chile; ChileFil: Nespolo, Roberto F.. Universidad Austral de Chile; ChileFil: Libkind Frati, Diego. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto Andino Patagónico de Tecnologías Biológicas y Geoambientales. Universidad Nacional del Comahue. Instituto Andino Patagónico de Tecnologías Biológicas y Geoambientales; ArgentinaFil: Cubillos, Francisco A.. Universidad de Santiago de Chile; Chil

    Determinación inversa de la conductividad térmica en madera de Pinus radiata

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    Se realizan experimentos a escala de laboratorio para caracterizar el secado artificial de madera de pino radiata a temperaturas convencionales y aceleradas, con el propósito de obtener datos que  permitan determinar la conductividad térmica de la madera mediante metodología inversa. El análisis comparativo muestra que la implementación de la metodología inversa desarrollada entrega información consistente con datos disponibles en la literatura especializada: conductividades térmicas crecientes con el aumento de la humedad y la temperatura, cuyos valores fluctúan entre 0,34 y 0,56 (W/m K) para variaciones de humedad entre 22% y 64%; y temperaturas entre 70°C a 90°C, respectivamente.Laboratory scale experiments are performed in order to characterize the artificial wood drying of Pinus radiata at conventional temperatures and accelerated temperatures. The experimental data allow to determine the wood thermal conductivity through inverse methodology. The comparative analysis shows that the implementation of the developed inverse methodology is consistent with  information available in the specialized literature; which means increased thermal conductivities with increased humidity and temperature, whose values oscillate between 0,34 and 0,56 (W/m K) to moisture variations between 22% and 64%; and temperatures between 70°C and 90°C, respectively

    Calentamiento por radiofrecuencia para esterilizar pinus radiata como material para embalajes. Parte 1: Tiempo total de tratamiento

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    In this work the total heating time was studied using radio frequency to sterilize wood packaging material of Pinus radiata, through the conditions 56 ° C and 60 ° C for 30 and 1 minutes respectively, according to international phytosanitary norms. The experimental tests were carried out in a laboratory radiofrequency equipment of 3 m3 capacity. The heating time was determined and prediction models were developed, depending on the thickness, plaque separation and wood loading volume, with confidence levels above 90%. The results showed that the total time of radiofrequency sterilization was greater in the surface of the pile and were statistically similar under both treatment conditions

    Mapping Pediatric Oncology Clinical Trial Collaborative Groups on the Global Stage

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    The global pediatric oncology clinical research landscape, particularly in Central and South America, Africa, and Asia, which bear the highest burden of global childhood cancer cases, is less characterized in the literature. Review of how existing pediatric cancer clinical trial groups internationally have been formed and how their research goals have been pursued is critical for building global collaborative research and data-sharing efforts, in line with the WHO Global Initiative for Childhood Cancer. METHODS: A narrative literature review of collaborative groups performing pediatric cancer clinical research in each continent was conducted. An inventory of research groups was assembled and reviewed by current pediatric cancer regional and continental leaders. Each group was narratively described with identification of common structural and research themes among consortia. RESULTS: There is wide variability in the structure, history, and goals of pediatric cancer clinical trial collaborative groups internationally. Several continental regions have longstanding endogenously-formed clinical trial groups that have developed and published numerous adapted treatment regimens to improve outcomes, whereas other regions have consortia focused on developing foundational database registry infrastructure supported by large multinational organizations or twinning relationships. CONCLUSION: There cannot be a one-size-fits-all approach to increasing collaboration between international pediatric cancer clinical trial groups, as this requires a nuanced understanding of local stakeholders and resources necessary to form partnerships. Needs assessments, performed either by local consortia or in conjunction with international partners, have generated productive clinical trial infrastructure. To achieve the goals of the Global Initiative for Childhood Cancer, global partnerships must be sufficiently granular to account for the distinct needs of each collaborating group and should incorporate grassroots approaches, robust twinning relationships, and implementation science

    Local hydrological conditions influence tree diversity and composition across the Amazon basin

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    Tree diversity and composition in Amazonia are known to be strongly determined by the water supplied by precipitation. Nevertheless, within the same climatic regime, water availability is modulated by local topography and soil characteristics (hereafter referred to as local hydrological conditions), varying from saturated and poorly drained to well-drained and potentially dry areas. While these conditions may be expected to influence species distribution, the impacts of local hydrological conditions on tree diversity and composition remain poorly understood at the whole Amazon basin scale. Using a dataset of 443 1-ha non-flooded forest plots distributed across the basin, we investigate how local hydrological conditions influence 1) tree alpha diversity, 2) the community-weighted wood density mean (CWM-wd) – a proxy for hydraulic resistance and 3) tree species composition. We find that the effect of local hydrological conditions on tree diversity depends on climate, being more evident in wetter forests, where diversity increases towards locations with well-drained soils. CWM-wd increased towards better drained soils in Southern and Western Amazonia. Tree species composition changed along local soil hydrological gradients in Central-Eastern, Western and Southern Amazonia, and those changes were correlated with changes in the mean wood density of plots. Our results suggest that local hydrological gradients filter species, influencing the diversity and composition of Amazonian forests. Overall, this study shows that the effect of local hydrological conditions is pervasive, extending over wide Amazonian regions, and reinforces the importance of accounting for local topography and hydrology to better understand the likely response and resilience of forests to increased frequency of extreme climate events and rising temperatures
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