1,244 research outputs found
Altitude-wind-tunnel Investigation of Tail-pipe Burner with Converging Conical Burner Section on J35-A-5 Turbojet Engine
An investigation of turbojet-engine thrust augmentation by means of tail-pipe burning has been conducted in the NACA Lewis altitude wind tunnel
Detecting and Mitigating Denial-of-Service Attacks on Voice over IP Networks
Voice over IP (VoIP) is more susceptible to Denial of Service attacks than traditional data traffic, due to the former's low tolerance to delay and jitter. We describe the design of our VoIP Vulnerability Assessment Tool (VVAT) with which we demonstrate vulnerabilities to DoS attacks inherent in many of the popular VoIP applications available today. In our threat model we assume an adversary who is not a network administrator, nor has direct control of the channel and key VoIP elements. His aim is to degrade his victim's QoS without giving away his presence by making his attack look like a normal network degradation. Even black-boxed, applications like Skype that use proprietary protocols show poor performance under specially crafted DoS attacks to its media stream. Finally we show how securing Skype relays not only preserves many of its useful features such as seamless traversal of firewalls but also protects its users from DoS attacks such as recording of conversations and disruption of voice quality. We also present our experiences using virtualization to protect VoIP applications from 'insider attacks'.
Our contribution is two fold we: 1) Outline a threat model for VoIP, incorporating our attack models in an open-source network simulator/emulator allowing VoIP vendors to check their software for vulnerabilities in a controlled environment before releasing it. 2) We present two promising approaches for protecting the confidentiality, availability and authentication of VoIP Services
Defining persistent hotspots:Areas that fail to decrease meaningfully in prevalence after multiple years of mass drug administration with praziquantel for control of schistosomiasis
Additional Evaluation of the Point-of-Contact Circulating Cathodic Antigen Assay for Schistosoma mansoni Infection.
Studies of the urine-based point-of-contact cathodic circulating antigen test (POC-CCA) in Schistosoma mansoni-endemic settings in Africa indicate it has good sensitivity in detecting infections, but in areas of low prevalence, the POC-CCA can be positive for persons who are egg-negative by Kato-Katz stool assays. We examined the POC-CCA assay for: (a) batch-to-batch stability; (b) intra-reader and inter-reader variability; (c) day-to-day variability compared to Kato-Katz stool assays, and (d) to see if praziquantel (PZQ) treatment converted Kato-Katz-negative/POC-CCA positive individuals to POC-CCA negativity. We found essentially no batch-to-batch variation, negligible intra-reader variability (2%), and substantial agreement for inter-reader reliability. Some day-to-day variation was observed over 5 days of urine collection, but less than the variation in Kato-Katz stool assays over 3 days. To evaluate the effect of treatment on Kato-Katz(-)/POC-CCA(+) children, 149 children in an area of 10-15% prevalence who were Kato-Katz(-) based on 3 stool samples but POC-CCA(+) were enrolled. Seven days after treatment (PZQ 40 mg/kg) samples were again collected and tested. Almost half (47%) POC-CCA positive children turned negative. Those still POC-CCA positive received a second treatment, and 34% of them turned POC-CCA negative upon this second treatment. Most who remained POC-CCA positive shifted each time to a "lesser" POC-CCA "level of positivity." The data suggest that most Kato-Katz-negative/POC-CCA positive individuals harbor low-intensity infections, and each treatment kills all or some of their adult worms. The data also suggest that when evaluated by a more sensitive assay, the effective cure rates for PZQ are significantly less than those inferred from fecal testing. These findings have public health significance for the mapping and monitoring of Schistosoma infections and in planning the transition from schistosomiasis morbidity control to elimination of transmission
Risk factors for Anopheles mosquitoes in rural and urban areas of Blantyre District, southern Malawi
BackgroundAlthough urban malaria transmission is low and seasonal, it remains a major public health problem. This study aimed at demonstrating the presence of Anopheles mosquitoes and their potential to transmit malaria in urban settings.MethodsTwo cross-sectional surveys were carried out in Blantyre District, Malawi, during the dry and wet seasons of 2008 and 2010, respectively. A map of Blantyre was divided into a grid of 400 cells, of which 60 cells were randomly selected. Five households located within 100 m from the centre of each selected cell were enrolled, a standard questionnaire was administered, and indoor resting mosquitoes were sampled.ResultsIn 2008 and 2010, a total of 960 and 1045 mosquitoes were collected, respectively. Anopheles funestus comprised 9.9% (n = 95) and 10.3% (n = 108) during the two surveys, respectively. Anopheles gambiae sensu lato (s.l.) was rarely detected during the second survey (n = 6; 0.6%). Molecular identification was performed on samples collected during the first survey, and An. funestus sensu stricto (s.s.) was the only sibling species detected. All the Anopheles mosquitoes were collected from households located in rural areas of Blantyre and none from urban areas. In univariate analysis, the presence of open eaves was associated with increased Anopheles prevalence, both during the dry (incidence rate ratio, IRR = 4.3; 95% CI 2.4 – 7.6) and wet (IRR = 2.47; 95% CI 1.7 – 3.59) seasons. Chances of detecting Anopheles spp. decreased with increasing altitude (IRR = 0.996; 95% CI 0.995 – 0.997) and during the dry season, but increased during the wet season (IRR = 1.0017; 95% CI 1.0012 – 1.0023). These factors remained significant following a multiple Poisson regression analysis. No association was found between insecticide-treated bednet ownership and the number of Anopheles mosquitoes detected.ConclusionsThe presence of An. funestus s.s and An. gambiae s.l. in the periphery of Blantyre city was an indication that malaria transmission was potentially taking place in these areas
Electronic Theory for the Nonlinear Magneto-Optical Response of Transition-Metals at Surfaces and Interfaces: Dependence of the Kerr-Rotation on Polarization and on the Magnetic Easy Axis
We extend our previous study of the polarization dependence of the nonlinear
optical response to the case of magnetic surfaces and buried magnetic
interfaces. We calculate for the longitudinal and polar configuration the
nonlinear magneto-optical Kerr rotation angle. In particular, we show which
tensor elements of the susceptibilities are involved in the enhancement of the
Kerr rotation in nonlinear optics for different configurations and we
demonstrate by a detailed analysis how the direction of the magnetization and
thus the easy axis at surfaces and buried interfaces can be determined from the
polarization dependence of the nonlinear magneto-optical response, since the
nonlinear Kerr rotation is sensitive to the electromagnetic field components
instead of merely the intensities. We also prove from the microscopic treatment
of spin-orbit coupling that there is an intrinsic phase difference of
90 between tensor elements which are even or odd under magnetization
reversal in contrast to linear magneto-optics. Finally, we compare our results
with several experiments on Co/Cu films and on Co/Au and Fe/Cr multilayers. We
conclude that the nonlinear magneto-optical Kerr-effect determines uniquely the
magnetic structure and in particular the magnetic easy axis in films and at
multilayer interfaces.Comment: 23 pages Revtex, preprintstyle, 2 uuencoded figure
Prayer-bots and religious worship on Twitter: a call for a wider research agenda
The automation of online social life is an urgent issue for researchers and the public alike. However, one of the most significant uses of such technologies seems to have gone largely unnoticed by the research community: religion. Focusing on Islamic Prayer Apps, which automatically post prayers from its users’ accounts, we show that even one such service is already responsible for millions of tweets daily, constituting a significant portion of Arabic-language Twitter traffic. We argue that the fact that a phenomenon of these proportions has gone unnoticed by researchers reveals an opportunity to broaden the scope of the current research agenda on online automation
Development and formative evaluation of the e-Health implementation toolkit
<b>Background</b> The use of Information and Communication Technology (ICT) or e-Health is seen as essential for a modern, cost-effective health service. However, there are well documented problems with implementation of e-Health initiatives, despite the existence of a great deal of research into how best to implement e-Health (an example of the gap between research and practice). This paper reports on the development and formative evaluation of an e-Health Implementation Toolkit (e-HIT) which aims to summarise and synthesise new and existing research on implementation of e-Health initiatives, and present it to senior managers in a user-friendly format.<p></p>
<b>Results</b> The content of the e-HIT was derived by combining data from a systematic review of reviews of barriers and facilitators to implementation of e-Health initiatives with qualitative data derived from interviews of "implementers", that is people who had been charged with implementing an e-Health initiative. These data were summarised, synthesised and combined with the constructs from the Normalisation Process Model. The software for the toolkit was developed by a commercial company (RocketScience). Formative evaluation was undertaken by obtaining user feedback. There are three components to the toolkit - a section on background and instructions for use aimed at novice users; the toolkit itself; and the report generated by completing the toolkit. It is available to download from http://www.ucl.ac.uk/pcph/research/ehealth/documents/e-HIT.xls<p></p>
<b>Conclusions</b> The e-HIT shows potential as a tool for enhancing future e-Health implementations. Further work is needed to make it fully web-enabled, and to determine its predictive potential for future implementations
Five-year impact of different multi-year mass drug administration strategies on childhood Schistosoma mansoni-associated morbidity:A combined analysis from the schistosomiasis consortium for operational research and evaluation cohort studies in the Lake Victoria Regions of Kenya and Tanzania
The WHO recommends mass treatment with praziquantel as the primary approach for; Schistosoma mansoni; -related morbidity control in endemic populations. The Schistosomiasis Consortium for Operational Research and Evaluation implemented multi-country, cluster-randomized trials to compare effectiveness of community-wide and school-based treatment (SBT) regimens on prevalence and intensity of schistosomiasis. To assess the impact of two different treatment schedules on; S. mansoni; -associated morbidity in children, cohort studies were nested within the randomized trials conducted in villages in Kenya and Tanzania having baseline prevalence ≥ 25%. Children aged 7-8 years were enrolled at baseline and followed to ages 11-12 years. Infection intensity and odds of infection were reduced both in villages receiving four years of annual community-wide treatment (CWT) and those who received biennial SBT over 4 years. These regimens were also associated with reduced odds of undernutrition and reduced odds of portal vein dilation at follow-up. However, neither hemoglobin levels nor the prevalence of the rare abnormal pattern C liver scores on ultrasound improved. For the combined cohorts, growth stunting worsened in the areas receiving biennial SBT, and maximal oxygen uptake as estimated by fitness testing scores declined under both regimens. After adjusting for imbalance in starting prevalence between study arms, children in villages receiving annual CWT had significantly greater decreases in infection prevalence and intensity than those villages receiving biennial SBT. Although health-related quality-of-life scores improved in both study arms, children in the CWT villages gained significantly more. We conclude that programs using annual CWT are likely to achieve better overall; S. mansoni; morbidity control than those implementing only biennial SBT
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