1,571 research outputs found

    Blue outliers among intermediate redshift quasars

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    [Oiii]{\lambda}{\lambda}4959,5007 "blue outliers" -- that are suggestive of outflows in the narrow line region of quasars -- appear to be much more common at intermediate z (high luminosity) than at low z. About 40% of quasars in a Hamburg ESO intermediate-z sample of 52 sources qualify as blue outliers (i.e., quasars with [OIII] {\lambda}{\lambda}4959,5007 lines showing large systematic blueshifts with respect to rest frame). We discuss major findings on what has become an intriguing field in active galactic nuclei research and stress the relevance of blue outliers to feedback and host galaxy evolution.Comment: Accepted for publication in Astrophysics and Space Science, Special Issue on Line Shifts in Astrophysics and Laboratory Plasm

    Charge Conjugation from Space-Time Inversion

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    We show that the CPT group of the Dirac field emerges naturally from the PT and P (or T) subgroups of the Lorentz group.Comment: 4 pages, no figure

    Black hole mass estimates in quasars - A comparative analysis of high- and low-ionization lines

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    The inter-line comparison between high- and low-ionization emission lines has yielded a wealth of information on the quasar broad line region (BLR) structure and dynamics, including perhaps the earliest unambiguous evidence in favor of a disk + wind structure in radio-quiet quasars. We carried out an analysis of the CIV 1549 and Hbeta line profiles of 28 Hamburg-ESO high luminosity quasars and of 48 low-z, low luminosity sources in order to test whether the high-ionization line CIV 1549 width could be correlated with Hbeta and be used as a virial broadening estimator. We analyze intermediate- to high-S/N, moderate resolution optical and NIR spectra covering the redshifted CIV and Hβ\beta over a broad range of luminosity log L ~ 44 - 48.5 [erg/s] and redshift (0 - 3), following an approach based on the quasar main sequence. The present analysis indicates that the line width of CIV 1549 is not immediately offering a virial broadening estimator equivalent to Hβ\beta. At the same time a virialized part of the BLR appears to be preserved even at the highest luminosities. We suggest a correction to FWHM(CIV) for Eddington ratio (using the CIV blueshift as a proxy) and luminosity effects that can be applied over more than four dex in luminosity. Great care should be used in estimating high-L black hole masses from CIV 1549 line width. However, once corrected FWHM(CIV) values are used, a CIV-based scaling law can yield unbiased MBH values with respect to the ones based on Hβ\beta with sample standard deviation ~ 0.3 dex.Comment: 43 pages, 15 Figures, submitted to A&

    Telomere Length Measurements of Human and Mouse Cells by Fluorescence in situ Hybridization

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    From MFN to SFN: Performance Prediction Through Machine Learning

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    In the last decade, the transition of digital terrestrial television (DTT) systems from multi-frequency networks (MFNs) to single-frequency networks (SFNs) has become a reality. SFN offers multiple advantages concerning MFN, such as more efficient management of the radioelectric spectrum, homogenizing the network parameters, and a potential SFN gain. However, the transition process can be cumbersome for operators due to the multiple measurement campaigns and required finetuning of the final SFN system to ensure the desired quality of service. To avoid time-consuming field measurements and reduce the costs associated with the SFN implementation, this paper aims to predict the performance of an SFN system from the legacy MFN and position data through machine learning (ML) algorithms. It is proposed a ML concatenated structure based on classification and regression to predict SFN electric-field strength, modulation error ratio, and gain. The model's training and test process are performed with a dataset from an SFN/MFN trial in Ghent, Belgium. Multiple algorithms have been tuned and compared to extract the data patterns and select the most accurate algorithms. The best performance to predict the SFN electric-field strength is obtained with a coefficient of determination (R2) of 0.93, modulation error ratio of 0.98, and SFN gain of 0.89 starting from MFN parameters and position data. The proposed method allows classifying the data points according to positive or negative SFN gain with an accuracy of 0.97

    Survival of chemoresistant cancer cells exposed to X-rays and heavy ions

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    Essential and checkpoint functions of budding yeast ATM and ATR during meiotic prophase are facilitated by differential phosphorylation of a meiotic adaptor protein, Hop1

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    A hallmark of the conserved ATM/ATR signalling is its ability to mediate a wide range of functions utilizing only a limited number of adaptors and effector kinases. During meiosis, Tel1 and Mec1, the budding yeast ATM and ATR, respectively, rely on a meiotic adaptor protein Hop1, a 53BP1/Rad9 functional analog, and its associated kinase Mek1, a CHK2/Rad53-paralog, to mediate multiple functions: control of the formation and repair of programmed meiotic DNA double strand breaks, enforcement of inter-homolog bias, regulation of meiotic progression, and implementation of checkpoint responses. Here, we present evidence that the multi-functionality of the Tel1/Mec1-to-Hop1/Mek1 signalling depends on stepwise activation of Mek1 that is mediated by Tel1/Mec1 phosphorylation of two specific residues within Hop1: phosphorylation at the threonine 318 (T318) ensures the transient basal level Mek1 activation required for viable spore formation during unperturbed meiosis. Phosphorylation at the serine 298 (S298) promotes stable Hop1-Mek1 interaction on chromosomes following the initial phospho-T318 mediated Mek1 recruitment. In the absence of Dmc1, the phospho-S298 also promotes Mek1 hyper-activation necessary for implementing meiotic checkpoint arrest. Taking these observations together, we propose that the Hop1 phospho-T318 and phospho-S298 constitute key components of the Tel1/Mec1- based meiotic recombination surveillance (MRS) network and facilitate effective coupling of meiotic recombination and progression during both unperturbed and challenged meiosis

    Efecto del bioplaguicida Bacillus thuringiensis (Berliner, 1911), cepa 344, en organismos indicadores del compartimiento acuático.

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    Resumen: El Bacillus thuringiensis (Berliner, 1911) (Bt) es una bacteria que contiene endotoxinas con acción insecticida para varias especies. A pesar de la conocida inocuidad de la utilización de Bt y otros bioplaguicidas utilizados en la lucha contra las plagas, ha habido algunos informes acerca de las infecciones y los efectos adversos sobre los organismos no blanco, entre estos, especies acuáticas. En este estudio, se evaluó los efectos derivados de la exposición a la cepa 344 del Bt (Bt344) en algunos organismos de diferentes niveles tróficos de la cadena alimentaria acuática. Los organismos de prueba estuvieron expuestos a concentraciones correspondientes a más de 1.000 veces la tasa de aplicación efectiva para controlar el gusano cogollero del maíz (Spodoptera frugiperda). El Bt344 no alteró los patrones de crecimiento de las algas Pseudokirchneriella subcapitata. Una tasa de mortalidad significativa equivalente a 8,9%, pero menor que el límite aceptable para el control (10%), se registró para el pez Hyphessobrycon scholzei. Sin embargo, la exposición al agente biológico disminuyó la supervivencia de Daphnia similis en 44,8%, en comparación con el control. Esto sugiere un riesgo para algunas especies acuáticas de invertebrados

    Heart rate variability in association with frequent use of household sprays and scented products in SAPALDIA

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    Background: Household cleaning products are associated with adverse respiratory health outcomes, but the cardiovascular health effects are largely unknown.Objective: We determined if long-term use of household sprays and scented products at home was associated with reduced heart rate variability (HRV), a marker of autonomic cardiac dysfunction.Methods: We recorded 24-hr electrocardiograms in a cross-sectional survey of 581 Swiss adults, 1, 1-3, or 4-7 days/week, unexposed (reference)] of using cleaning sprays, air freshening sprays, and scented products.Results: Decreases in 24-hr SDNN and TP were observed with frequent use of all product types, but the strongest reductions were associated with air freshening sprays. Compared with unexposed participants, we found that using air freshening sprays 4-7 days/week was associated with 11% [95% confidence interval (CI): -20%, -2%] and 29% (95% CI: -46%, -8%) decreases in 24-hr SDNN and TP, respectively. Inverse associations of 24-SDNN and TP with increased use of cleaning sprays, air freshening sprays, and scented products were observed mainly in participants with obstructive lung disease (p > 0.05 for interactions).Conclusions: In predominantly older adult women, long-term frequent use of household spray and scented products was associated with reduced HRV, which suggests an increased risk of cardiovascular health hazards. People with preexisting pulmonary conditions may be more susceptibl
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