Enfermedad de Jacob asociada con el síndrome de disfunción de la articulación temporomandibular: presentación de un caso

La enfermedad de Jacob se describe como una entidad infrecuente en la cual se establece una formación articular sinovial entre una apófisis coronoide mandibular elongada y el hueso malar homolateral. El Síndrome de disfunción de la articulación temporomandibular (ATM) ha sido postulado como posible factor etiológico del alargamiento este proceso coronoideo. Presentamos el caso de una mujer de 23 años con un desplazamiento discal de ATM de larga evolución y limitación de la apertura oral, que desarrolló una asimetría malar progresiva. La paciente fue sometida a tratamiento quirúrgico mediante una coronoidectomía intraoral y una artroscopia de la ATM homolateral en el mismo acto operatorio. El diagnóstico histológico de la apófisis coronoide examinada fue de exóstosis óseo-cartilaginosa con presencia de fibrocartílago articular en dicha formación. A pesar de la baja prevalencia de esta patología, debe ser considerada como un posible diagnóstico en aquellos pacientes con limitación progresiva de la apertura oral de larga evolución, si bien en ocasiones puede acompañarse de una disfunción articular crónica concomitante como posible causa de la misma.Jacob´s disease is regarded a rare condition in which a joint formation is established between an enlarged mandibular coronoid process and the inner aspect of the zygomatic body. Chronic temporomandibular joint (TMJ) disk displacement has been proposed as etiological factor of coronoid process enlargement. We present a 23-year-old woman with long-standing TMJ dysfunction and restricted interincisal opening, who developed a progressive zygomatic assymetry. The patient underwent treatment by intraoral coronoidectomy and homolateral TMJ arthroscopy in the same surgery. The histopathological diagnosis of the coronoid sample was cartilage-capped exostoses with presence of articular fibrous cartilage. Although the low prevalence of this entity, it should be considered as a possible diagnosis in patients with progressive limitation of mouth opening, although a TMJ syndrome may be present as a cause of this entity

Acute effect of complexity in basketball on cognitive capacity

Background: Executive functions, notably inhibition, significantly influence decision-making and behavioral regulation in team sports. However, more research must be conducted on individual player characteristics such as experience and motor skills. This study assessed how accumulated practical experience moderates inhibition in response to varying task difficulty levels. Methods: Forty-four university students (age: 20.36 ± 3.13 years) participated in this study with two sessions: one followed standard 1 × 1 basketball rules (“Regular Practice”), while the other imposed motor, temporal, and spatial restrictions (“Restriction Practice”). Functional difficulty was controlled by grouping pairs with similar skill levels. Flanker and Go-Nogo tasks were used. Results: Increasing complexity worsened cognitive performance (inhibition). “Restriction Practice” showed a significantly slower and less accurate performance in both tests than “Regular Practice” (p < 0.001). Experience positively impacted test speed and accuracy (p < 0.001). Conclusion: In sports, acute cognitive impacts are intrinsically linked to the task’s complexity and the athlete’s cognitive resources. In this sense, it is essential to adjust individually the cognitive demands of the tasks, considering each athlete’s specific cognitive abilities and capacities.This research was funded by grants awarded by the European Regional Development Fund (ERDF) Operational Programme Andalusia 2014–2020 (Spanish Research Agency); SEJ-746-UGR20 “Effect of the manipulation of contextual variables of physical exercise on mental load and cognitive, emotional and athletic performance.” Additionally, support was provided by the Camilo Cano Cathedra of Culture for Sport and Sport for Culture of the University of Alicante. Further funding was received from the Spanish Ministry of Science, Innovation, and Universities through Grant FPU19/06224 and the Spanish Ministry of Universities through Grant FPU20/02022

Effect of Research Impact on Emerging Camel Husbandry, Welfare and Social-Related Awareness

The lack of applied scientific research on camels, despite them being recognized as production animals, compels the reorganization of emerging camel breeding systems with the aim of achieving successful camel welfare management strategies all over the world. Relevant and properly-framed research widely impacts dissemination of scientific contents and drives public willingness to enhance ethically acceptable conditions for domestic animals. Consumer perception of this livestock industry will improve and high-quality products will be obtained. This paper draws on bibliometric indicators as promoting factors for camel-related research advances, tracing historical scientific publications indexed in ScienceDirect directory from 1880–2019. Camel as a species did not affect Journal Citation Reports (JCR) impact (p > 0.05) despite the journal, author number, corresponding author origin, discipline and publication year affecting it (p < 0.001). Countries with traditionally well-established camel farming are also responsible for the papers with the highest academic impact. However, camel research advances may have only locally and partially influenced welfare related laws, so intentional harming acts and basic needs neglect may persist in these species. A sustainable camel industry requires those involved in camel research to influence business stakeholders and animal welfare advocacies by highlighting the benefits of camel wellbeing promotion, co-innovation partnership establishment and urgent enhancement of policy reform

Evolution des exploitations ovines et caprines en Méditerranée durant les dix dernières années. I. Proposition d'une méthodologie d'étude

L’objectif de ce travail est l’élaboration d’une méthode d’analyse comparative interrégionale de la situation et des évolutions des systèmes de production ovine et caprine. Des questionnaires d’enquête différents sont élaborés à destination des éleveurs d’une part, des agents de développement puis des personnes chargées de la commercialisation d’autre part. Des analyses statistiques de variance sont utilisées pour construire des typologies d’exploitation sur la base de la situation actuelle et de l’évolution des exploitations au cours des 10 dernières années. La méthode d’analyse clinique des écosystèmes a pour objet : (i) de connaître les points forts et les points faibles des systèmes et les relations de cause à effet ; (ii) de prévoir de manière prospective l’évolution future de chaque type d’exploitation ; et (iii) de proposer des actions concrètes pour optimiser les perspectives favorables de chaque système. Cette démarche s’inscrit dans l’Observatoire des systèmes de production ovine et caprine du réseau FAO/CIHEAM de recherche coopérative sur les ovins et les caprins.“Evolution of the sheep and goat farms in the Mediterranean over the last ten years. I. Proposal of a study methodology”. The main objective of this paper is to develop a methodology that could be used in diverse regions to make a comparative analysis of situation and changes that may occur in goat and sheep sectors among different regions from the same or different countries. This process has been elaborated for breeders on one hand, for extension and commercial agents on the other. Statistical analysis of variance is used to build up a typology of farms on the basis of the actual situation and changes in farms for the 10 last years. The method of clinical analysis of variance of ecosystems is used to: (i) determine system strengths and weaknesses and the cause-result relationships; (ii) foresee system evolution based on the established cluster; and (iii) propose actions to optimize future evolution in every system according to real possibilities in each particular case. This initiative is an action of the Monitoring Body of sheep and goat production systems of the FAO/CIHEAM network of cooperative research on sheep and goats

Over tourism in the city of Granada?: an analysis of the perception of tourists, residents and local political parties

La ciudad de Granada es una de las más visitadas del interior de la península, conociendo un proceso de turistificación que se ha acentuado en la última década. Sus atractivos culturales y monumentales son los principales motivos de llegada. Además incluso, muchos de estos turistas finalmente fijan su lugar de residencia en la ciudad dando lugar a un proceso de gentrificación. Con este trabajo se persiguen varios fines. A través de un estudio cualitativo gracias a dos modelos de preguntas y a una serie de indicadores perceptuales clave, se analiza la opinión de los turistas y residentes locales sobre el destino y sobre el sector, es decir, sus percepciones sicológica y social, respectivamente. Por otra parte, también se considera el posicionamiento de los partidos políticos ante el sector y su problemática. ¿Existe entre la población local turismofilia o turismofobia?, ¿los turistas se encuentran satisfechos con la experiencia turística en el destino, o lo encuentran masificado?, ¿los partidos políticos consideran que existe un sobredimensionamiento de la actividad? En líneas generales, aunque se aprecia el inicio de una serie de problemas y conflictos relacionados con el sector (sensación de masificación entre los turistas y residentes, pisos turísticos ilegales, dificultad de poder visitar los principales monumentos, ruido, inseguridad y delincuencia, pérdida de estilos de vida locales, …), tanto turistas como residentes no perciben que la actividad sea negativa, sino al contrario. Estos atisbos iniciales pueden ser atribuidos también a una carencia de una adecuada gestión y planificación turística.The city of Granada has become one of the most visited cities in inland Spain, with tourism booming over the last decade. Tourists are attracted to both its culture and its many historic monuments and edifices. Many tourists eventually decide actually to settle in the city, and this has led to the process of gentrification in certain areas. Utilizing two questionnaires and other perceptual indicators, the opinion of both tourists and residents about Granada is herein analysed, with particular regard to psychological and social factors. Also, the impact on political parties affected by this influx is studied. Does the local population of Granada view tourism with welcoming arms or with mistrust and concern? Are tourists satisfied with their experience in the town, or do they find it overcrowded with too many tourists? Do the local political parties concur that there is a problem with over tourism? Some problems and conflicts are noted: both tourists and locals feeling that there is overcrowding, illegal use of tourist rental flats, difficulty visiting local attractions due to long lines and overcrowding, excess noise, crime, and a loss of a feeling of local culture and lifestyle for residents. Both tourists and residents want the best experience, but proper tourism management and planning is essential for this process to move forward

Application of Photon Strength Functions to (n,g ) measurements with the n_TOF TAC

The neutron capture cross section measurements at the CERN n_TOF facility are performed using a new detection system, the segmented Total Absorption Calorimeter (TAC). All measurements are performed in reference to the well known Au σ(n,γ). The accuracy of the measurements depends on the accuracy of the TAC detection efficiency, which is calculated by means of Monte Carlo simulations. In this MC simulation photon strength functions and level densities play a major role as ingredients used for the generation of primary events, that is the electromagnetic cascades following the (n,γ) process. We have calculated the TAC detection efficiency for the case of Au (n,γ) by adjusting the photon strength functions of Au so that the simulation reproduces the experimental data. Both the MC method and the uncertainty of the results are discussed

Deciphering the quality of SARS-CoV-2 specific T-cell response associated with disease severity, immune memory and heterologous response

SARS-CoV-2 specific T-cell response has been associated with disease severity, immune memory and heterologous response to endemic coronaviruses. However, an integrative approach combining a comprehensive analysis of the quality of SARS-CoV-2 specific T-cell response with antibody levels in these three scenarios is needed. In the present study, we found that, in acute infection, while mild disease was associated with high T-cell polyfunctionality biased to IL-2 production and inversely correlated with anti-S IgG levels, combinations only including IFN-γ with the absence of perforin production predominated in severe disease. Seven months after infection, both non-hospitalised and previously hospitalised patients presented robust anti-S IgG levels and SARS-CoV-2 specific T-cell response. In addition, only previously hospitalised patients showed a T-cell exhaustion profile. Finally, combinations including IL-2 in response to S protein of endemic coronaviruses were the ones associated with SARS-CoV-2 S-specific T-cell response in pre-COVID-19 healthy donors’ samples. These results could have implications for protective immunity against SARS-CoV-2 and recurrent COVID-19 and may help for the design of new prototypes and boosting vaccine strategies

Obstructive Sleep Apnoea Syndrome, Endothelial Function and Markers of Endothelialization. Changes after CPAP

Study objectives This study tries to assess the endothelial function in vivo using flow-mediated dilatation (FMD) and several biomarkers of endothelium formation/restoration and damage in patients with obstructive sleep apnoea (OSA) syndrome at baseline and after three months with CPAP therapy. Design Observational study, before and after CPAP therapy. Setting and Patients We studied 30 patients with apnoea/hypopnoea index (AHI) > 15/h that were compared with themselves after three months of CPAP therapy. FMD was assessed non-invasively in vivo using the Laser-Doppler flowmetry. Circulating cell-free DNA (cf-DNA) and microparticles (MPs) were measured as markers of endothelial damage and the vascular endothelial growth factor (VEGF) was determined as a marker of endothelial restoration process. Measurements and results After three month with CPAP, FMD significantly increased (1072.26 +/- 483.21 vs. 1604.38 +/- 915.69 PU, p<0.005) cf-DNA and MPs significantly decreased (187.93 +/- 115.81 vs. 121.28 +/- 78.98 pg/ml, p<0.01, and 69.60 +/- 62.60 vs. 39.82 +/- 22.14 U/mu L, p<0.05, respectively) and VEGF levels increased (585.02 +/- 246.06 vs. 641.11 +/- 212.69 pg/ml, p<0.05). These changes were higher in patients with more severe disease. There was a relationship between markers of damage (r = -0.53, p< 0.005) but not between markers of damage and restoration, thus suggesting that both types of markers should be measured together. Conclusions CPAP therapy improves FMD. This improvement may be related to an increase of endothelial restoration process and a decrease of endothelial damage

Comportamento das doenças respiratórias no serviço de urgência do hospital pediátrico de Cienfuegos

Introduction: are largely responsible for the morbidity treated in pediatric institutions. Objective: to characterize the respiratory diseases behavior in the emergency department at the Hospital Pediátrico Universitario “Paquito González Cueto”, Cienfuegos, in 2020. Method: an observational, descriptive, and cross-sectional study was conducted in the Emergency Department at the Pediatric Hospital in Cienfuegos, from January through December, 2020. Population studied were children 0 to 18 years of age from Cienfuegos province who attended at the emergency department during the study period. The main variables assessed were the age groups and demand for medical consultations. All the statistical methods and techniques applied were those in the descriptive statistics. Results: the highest incidence of acute respiratory infections was reported in the months of march and February (758 and 668 consultations respectively), coinciding in the same period the bronchial asthma crises (101 and 111 consultations respectively). Pneumonias showed the highest morbidity in march (31.6 % of the cases). The predominant age group was 1 to 4 years. Conclusions: the respiratory diseases behavior was within the expected parameters, leading in incidence and morbidity the age group1 to 4 years and the first quarter of the year was the highest period on medical consultations medical consultations related to diseases studied.Introducción: las enfermedades respiratorias son responsables, en gran medida, de la morbilidad atendida en las instituciones pediátricas.Objetivo: caracterizar el comportamiento de las afecciones respiratorias en el servicio de Urgencias del Hospital Pediátrico Universitario “Paquito González Cueto”, de Cienfuegos, durante el año 2020. Método: se realizó un estudio observacional, descriptivo de corte transversal en el Servicio de Urgencias del Hospital Pediátrico de Cienfuegos del 1 de enero al 31 de diciembre de 2020. La población estudiada fueron los habitantes de edad pediátrica comprendida de 0 a 18 años de la provincia de Cienfuegos que asistieron al escenario y periodo de estudio. Las principales variables de estudio consideradas fueron los grupos de edades y demanda de consultas médicas. Los métodos y técnicas estadísticas utilizadas fueron de la estadística descriptiva. Resultados: la mayor incidencia de las infecciones respiratorias agudas fue en el mes de marzo y febrero con un total de 758 y 668 consultas respectivamente, coincidiendo este período para las crisis de asma bronquial con 101 y 111 consultas en iguales meses. Las neumonías mostraron mayor morbilidad en marzo con el 31,6 % de los casos. El predominio según grupo de edad se encontró de 1-4 años en las enfermedades estudiadas. Conclusiones: el comportamiento de las enfermedades respiratorias se encontró dentro de los parámetros esperados, siendo el grupo etario de mayor incidencia y morbilidad el de 1-4 años de edad, con predominio del número de consultas en el primer trimestre del año.Introdução: as doenças respiratórias são responsáveis, em grande parte, pela morbidade observada nas instituições pediátricas. Objetivo: caracterizar o comportamento das doenças respiratórias no Serviço de Emergência do Hospital Pediátrico Universitario “Paquito González Cueto”, em Cienfuegos, durante o ano de 2020. Método: foi realizado um estudo observacional, descritivo, transversal, no Serviço de Urgência do Hospital Pediátrico de Cienfuegos de 1 de janeiro a 31 de dezembro de 2020. A população estudada foi constituída por habitantes em idade pediátrica de 0 a 18 anos da província de Cienfuegos que frequentou o estágio e período de estudos. As principais variáveis consideradas no estudo foram a faixa etária e a demanda por consultas médicas. Os métodos e técnicas estatísticas utilizadas foram estatísticas descritivas. Resultados: a maior incidência de infecções respiratórias agudas foi em março e fevereiro com um total de 758 e 668 consultas, respectivamente, período esse coincidindo para as crises de asma brônquica com 101 e 111 consultas nos mesmos meses. A pneumonia apresentou maior morbidade em março com 31,6% dos casos. A predominância de acordo com a faixa etária foi encontrada entre 1 a 4 anos nas doenças estudadas. Conclusões: o comportamento das doenças respiratórias ficou dentro dos parâmetros esperados, sendo a faixa etária de maior incidência e morbidade a de 1 a 4 anos, com predomínio do número de consultas no primeiro trimestre do ano

Behavior of respiratory diseases in the emergency service of the pediatric hospital of Cienfuegos

Introduction: are largely responsible for the morbidity treated in pediatric institutions. Objective: to characterize the respiratory diseases behavior in the emergency department at the Hospital Pediátrico Universitario “Paquito González Cueto”, Cienfuegos, in 2020. Method: an observational, descriptive, and cross-sectional study was conducted in the Emergency Department at the Pediatric Hospital in Cienfuegos, from January through December, 2020. Population studied were children 0 to 18 years of age from Cienfuegos province who attended at the emergency department during the study period. The main variables assessed were the age groups and demand for medical consultations. All the statistical methods and techniques applied were those in the descriptive statistics. Results: the highest incidence of acute respiratory infections was reported in the months of march and February (758 and 668 consultations respectively), coinciding in the same period the bronchial asthma crises (101 and 111 consultations respectively). Pneumonias showed the highest morbidity in march (31.6 % of the cases). The predominant age group was 1 to 4 years. Conclusions: the respiratory diseases behavior was within the expected parameters, leading in incidence and morbidity the age group1 to 4 years and the first quarter of the year was the highest period on medical consultations medical consultations related to diseases studied