formation morphology and interpretation of darkened faecal spherulites

Abstract Faecal spherulites are a common indicator of dung in archaeological deposits and most of the basic processes of their formation and taphonomy have been explained. However, a darkened form is also regularly found, ranging from slightly transparent through to completely opaque. These have been less well studied, so we set out here to understand what actually causes the darkening and to determine the range of conditions required to produce the changes. Darkened spherulites were successfully created by heating dung to between 500 °C and 700 °C with the gaseous products constrained. The maximum production in our experiments was at 600 °C. The darkened spherulites often expanded during the alteration process and some of the expanded ones become distorted. SEM examination was only possible through destructive preparation processes, but examples were found showing expansion beyond the normal size range. These had a distinctive internal structure characterised by very fine crystallinity and larger scale fracturing, perhaps resulting from organic matter loss and/or CaCO 3 alteration. Prolonged oxidative heating failed to remove the darkening, leading to the possibility that it is partly a structural phenomenon, with opacification arising from compound relief. Based on these findings, darkened spherulites can now be confidently interpreted as; resulting from dung being heated in conditions of limited gaseous exchange to between 500 and 700 °C, then not heated again beyond ca. 700 °C. These sorts of conditions could occur, around the edge of, or beneath, any fire where fresh dung is being burned or where the existing stratigraphy has a dung component

Patients with breakthrough reactions to iodinated contrast media have low incidence of positive skin tests

BACKGROUND: The term "breakthrough reactions" designates repeated hypersensitivity reactions to iodinated contrast media (ICM) despite premedication with glucocorticoids and antihistamines. We aimed to retrospectively evaluate the rate of positive skin test (STs) in our cohort of patients with previous breakthrough reactions to different ICMs. METHODS: A series of 35 patients, who experienced at least one breakthrough reaction to ICM and who underwent STs within 6 months from the reaction were studied, and results were compared to a control group of patients with a first hypersensitivity reaction occurred without premedication. Skin prick tests (SPT), intradermal tests (IDT) and patch tests (PT) at different dilutions, with a set of three to four ICM were performed. RESULTS: Of the 35 patients with prior breakthrough reactions, 57% had an immediate reaction (IR) and 43% had a non-immediate reaction (NIR). Patients who experienced the first hypersensitivity IR or NIR, later had one or more breakthrough IR or NIR, respectively. Overall, 29% (10/35) of patients with prior breakthrough reactions resulted positive to STs compared to 57% (16/28) of the control group (p < 0.05). No significant difference in allergy history, age, sex, other clinical / demographic features nor chronic use of ACE-inhibitor, beta-blockers or NSAIDs was observed. CONCLUSION: This preliminary finding suggests that patients with prior breakthrough reactions have significantly lower immunologically proven ICM reactions (positive STs) if compared to non-breakthrough patients. According to that, a considerable number of breakthrough reactions seems to be non-allergic hypersensitivity reactions or reactions which could be mostly prevented by a proper, well-timed skin testing. Larger prospective studies are needed to confirm these results, with a more careful analysis of patients' risk factors, a laboratory assessment that includes an in vitro allergy diagnostics, and hopefully a drug provocation test for selected cases

The mineralogical composition of calcium and calcium-magnesium carbonate pedofeatures of calcareous soils in the European prairie ecodivision in Hungary

Abstract There is little data on the mineralogy of carbonate pedofeatures in the calcareous soils in Hungary which belong to the European prairie ecodivision. The aim of the present study is to enrich these data. The mineralogical composition of the carbonate pedofeatures from characteristic profiles of the calcareous soils in Hungary was studied by X-ray diffractometry, thermal analysis, SEM combined with microanalysis, and stable isotope determination. Regarding carbonate minerals only aragonite, calcite (+ magnesian calcite) and dolomite (+proto-dolomite) were identified in carbonate grains, skeletons and pedofeatures. The values relating, respectively, to stable isotope compositions (C13, O18) of carbonates in chernozems and in salt-affected soils were in the same range as those for recent soils (latter data reported earlier). There were no considerable differences between the values for the carbonate nodules and tubules from the same horizons, nor were there significant variations between the values of the same pedofeatures from different horizons (BC-C) of the same profile. Thus it can be assumed that there were no considerable changes in conditions of formation. Tendencies were recognized in the changes of (i) carbonate mineral associations, (ii) the MgCO3 content of calcites, (iii) the corrected decomposition temperatures, and (iv) the activation energies of carbonate thermal decompositions among the various substance-regimes of soils. Differences were found in substance-regimes types of soils rather than in soil types

Formation, morphology and interpretation of darkened faecal spherulites

Abstract Faecal spherulites are a common indicator of dung in archaeological deposits and most of the basic processes of their formation and taphonomy have been explained. However, a darkened form is also regularly found, ranging from slightly transparent through to completely opaque. These have been less well studied, so we set out here to understand what actually causes the darkening and to determine the range of conditions required to produce the changes. Darkened spherulites were successfully created by heating dung to between 500 °C and 700 °C with the gaseous products constrained. The maximum production in our experiments was at 600 °C. The darkened spherulites often expanded during the alteration process and some of the expanded ones become distorted. SEM examination was only possible through destructive preparation processes, but examples were found showing expansion beyond the normal size range. These had a distinctive internal structure characterised by very fine crystallinity and larger scale fracturing, perhaps resulting from organic matter loss and/or CaCO 3 alteration. Prolonged oxidative heating failed to remove the darkening, leading to the possibility that it is partly a structural phenomenon, with opacification arising from compound relief. Based on these findings, darkened spherulites can now be confidently interpreted as; resulting from dung being heated in conditions of limited gaseous exchange to between 500 and 700 °C, then not heated again beyond ca. 700 °C. These sorts of conditions could occur, around the edge of, or beneath, any fire where fresh dung is being burned or where the existing stratigraphy has a dung component