Nanosized patterns as reference structures for macroscopic transport properties and vortex phases in YBCO films

This paper studies the striking correlation between nanosized structural patterns in YBCO films and macroscopic transport current. A nanosized network of parallel Josephson junctions laced by insulating dislocations is almost mimicking the grain boundary structural network. It contributes to the macroscopic properties and accounts for the strong intergranular pinning across the film in the intermediate temperature range. The correlation between the two networks enables to find out an outstanding scaling law in the (Jc,B) plane and to determine meaningful parameters concerning the matching between the vortex lattice and the intergranular defect lattice. Two asymptotic behaviors of the pinning force below the flux flow regime are checked: the corresponding vortex phases are clearly individuated.Comment: 4 pages, 4 figure

Mixed-state microwave response in superconducting cuprates

We report measurements of the magnetic-field induced microwave complex resistivity in REBa$_{2}$Cu$_{3}$O$_{7-\delta}$ thin films, with RE = Y, Sm. Measurements are performed at 48 GHz by means of a resonant cavity in the end-wall-replacement configuration. The magnetic field dependence is investigated by applying a moderate (0.8 T) magnetic field along the c-axis. The measured vortex state complex resistivity in YBa$_{2}$Cu$_{3}$O$_{7-\delta}$ and SmBa$_{2}$Cu$_{3}$O$_{7-\delta}$ is analyzed within the well-known models for vortex dynamics. It is shown that attributing the observed response to vortex motion alone leads to inconsistencies in the as-determined vortex parameters (such as the vortex viscosity and the pinning constant). By contrast, attributing the entire response to field-induced pair breaking leads to a nearly quantitative description of the data.Comment: 6 pages, 4 figures, to be published in J. Supercond. as proceedings of 8th HTSHFF (May 26th-29th, 2004, Begur, Spain

On the use of lock-in thermography to monitor delamination growth in composite panels under compression

Abstract The success of composites in automotive, aerospace, and naval applications is mainly related to their aptitude to be tailored to obtain a final product that perfectly fulfills the design requirements. However, during both manufacturing processes and maintenance, some flaws, like delaminations (which may escape simple visual inspection), may be induced in composite structures. The presence of delaminations is of major concern for the load-carrying capability of carbon fiber-reinforced polymer panels. Indeed, delaminations can strongly affect the structural strength and may grow under in-service loads, leading sometimes to catastrophic failures. The aim of this work is to explore the use of lock-in thermography for the monitoring of delamination propagation in composite structures when subjected to generic multiaxial loading conditions. A stiffened composite panel with an embedded skin delamination subjected to compressive loading was taken as a benchmark to assess experimentally the effectiveness of lock-in thermography for monitoring the delamination propagation in situ during the compressive mechanical test. The delamination size as a function of the applied load, observed by lock-in thermography during the execution of the compressive test, was used to validate the results of preliminary numerical computations

JOSEPHSON JUNCTION NETWORK AS A TOOL TO SIMULATE INTERGRAIN SUPERCONDUCTING CHANNELS IN YBCO FILMS

Recent considerations on the physics of YBa 2 Cu 3 O 7-δ films made possible explaining their transport properties as flow of supercurrents through links between the granular structure of the film. The present work deals with the analysis of the Josephson junction network as a discrete set of parallel junctions (1D array) in quasi-static conditions and is aimed to compare the results of the simulations with the experimental findings, in particular with the plateau-like features in the critical current dependence on the magnetic field. Different regimes and vortex phases have been individuated and discussed

Effects of Ionizing Radiation and Long-Term Storage on Hydrated vs. Dried Cell Samples of Extremophilic Microorganisms

A main factor hampering life in space is represented by high atomic number nuclei and energy (HZE) ions that constitute about 1% of the galactic cosmic rays. In the frame of the “STARLIFE” project, we accessed the Heavy Ion Medical Accelerator (HIMAC) facility of the National Institute of Radiological Sciences (NIRS) in Chiba, Japan. By means of this facility, the extremophilic species Haloterrigena hispanica and Parageobacillus thermantarcticus were irradiated with high LET ions (i.e., Fe, Ar, and He ions) at doses corresponding to long permanence in the space environment. The survivability of HZE-treated cells depended upon either the storage time and the hydration state during irradiation; indeed, dry samples were shown to be more resistant than hydrated ones. With particular regard to spores of the species P. thermantarcticus, they were the most resistant to irradiation in a water medium: an analysis of the changes in their biochemical fingerprinting during irradiation showed that, below the survivability threshold, the spores undergo to a germination-like process, while for higher doses, inactivation takes place as a consequence of the concomitant release of the core’s content and a loss of integrity of the main cellular components. Overall, the results reported here suggest that the selected extremophilic microorganisms could serve as biological model for space simulation and/or real space condition exposure, since they showed good resistance to ionizing radiation exposure and were able to resume cellular growth after long-term storage

Surface-enhanced Raman spectroscopy of tears: Toward a diagnostic tool for neurodegenerative disease identification

Significance: A noninvasive method based on surface-enhanced Raman spectroscopy (SERS) of tears was proposed as a support for diagnosing neurodegenerative pathologies, including different forms of dementia and Alzheimer's disease (AD). In this field, timely and reliable discrimination and diagnosis are critical aspects for choosing a valid medical therapy, and new methods are highly required. Aim: The aim is to evince spectral differences in SERS response of human tears from AD affected, mild cognitive impaired (MCI), and healthy control (Ctr) subjects. Approach: Human tears were characterized by SERS coupled with multivariate data analysis. Thirty-one informed subjects (Ctr, MCI, and AD) were considered. Results: Average SERS spectra from Ctr, MCI, and AD subjects evidenced differences related to lactoferrin and lysozyme protein components. Quantitative changes were also observed by determining the intensity ratio between selected bands. We also constructed a classification model that discriminated among AD, MCI, and Ctr subjects. The model was built using the scores obtained by performing principal component analysis on specific spectral regions (i-PCA). Conclusions: The results are very encouraging with interesting perspectives for medical applications as support of clinical diagnosis and discrimination of AD from other forms of dementia

Medico-legal assessment of personal damage in older people: report from a multidisciplinary consensus conference

Ageing of the global population represents a challenge for national healthcare systems and healthcare professionals, including medico-legal experts, who assess personal damage in an increasing number of older people. Personal damage evaluation in older people is complex, and the scarcity of evidence is hindering the development of formal guidelines on the subject. The main objectives of the first multidisciplinary Consensus Conference on Medico-Legal Assessment of Personal Damage in Older People were to increase knowledge on the subject and establish standard procedures in this field. The conference, organized according to the guidelines issued by the Italian National Institute of Health (ISS), was held in Bologna (Italy) on June 8, 2019 with the support of national scientific societies, professional organizations, and stakeholders. The Scientific Technical Committee prepared 16 questions on 4 thematic areas: (1) differences in injury outcomes in older people compared to younger people and their relevance in personal damage assessment; (2) pre-existing status reconstruction and evaluation; (3) medico-legal examination procedures; (4) multidimensional assessment and scales. The Scientific Secretariat reviewed relevant literature and documents, rated their quality, and summarized evidence. During conference plenary public sessions, 4 pairs of experts reported on each thematic area. After the last session, a multidisciplinary Jury Panel (15 members) drafted the consensus statements. The present report describes Conference methods and results, including a summary of evidence supporting each statement, and areas requiring further investigation. The methodological recommendations issued during the Conference may be useful in several contexts of damage assessment, or to other medico-legal evaluation fields

Risk factors and prognosis of young stroke. The FUTURE study: A prospective cohort study. Study rationale and protocol

Contains fulltext : 98322.pdf (postprint version ) (Open Access)BACKGROUND: Young stroke can have devastating consequences with respect to quality of life, the ability to work, plan or run a family, and participate in social life. Better insight into risk factors and the long-term prognosis is extremely important, especially in young stroke patients with a life expectancy of decades. To date, detailed information on risk factors and the long-term prognosis in young stroke patients, and more specific risk of mortality or recurrent vascular events, remains scarce. METHODS/DESIGN: The FUTURE study is a prospective cohort study on risk factors and prognosis of young ischemic and hemorrhagic stroke among 1006 patients, aged 18-50 years, included in our study database between 1-1-1980 and 1-11-2010. Follow-up visits at our research centre take place from the end of 2009 until the end of 2011. Control subjects will be recruited among the patients' spouses, relatives or social environment. Information on mortality and incident vascular events will be retrieved via structured questionnaires. In addition, participants are invited to the research centre to undergo an extensive sub study including MRI. DISCUSSION: The FUTURE study has the potential to make an important contribution to increase the knowledge on risk factors and long-term prognosis in young stroke patients. Our study differs from previous studies by having a maximal follow-up of more than 30 years, including not only TIA and ischemic stroke but also hemorrhagic stroke, the addition of healthy controls and prospectively collect data during an extensive follow-up visit. Completion of the FUTURE study may provide better information for treating physicians and patients with respect to the prognosis of young stroke.8 p