2,327 research outputs found
A genome-wide investigation of the worldwide invader Sargassum muticum shows high success albeit (almost) no genetic diversity
Twenty years of genetic studies of marine invaders have shown that successful invaders are often characterized by native and introduced populations displaying similar levels of genetic diversity. This pattern is presumably due to high propagule pressure and repeated introductions. The opposite pattern is reported in this study of the brown seaweed, Sargassum muticum, an emblematic species for circumglobal invasions. Albeit demonstrating polymorphism in the native range, microsatellites failed to detect any genetic variation over 1,269 individuals sampled from 46 locations over the Pacific-Atlantic introduction range. Single-nucleotide polymorphisms (SNPs) obtained from ddRAD sequencing revealed some genetic variation, but confirmed severe founder events in both the Pacific and Atlantic introduction ranges. Our study thus exemplifies the need for extreme caution in interpreting neutral genetic diversity as a proxy for invasive potential. Our results confirm a previously hypothesized transoceanic secondary introduction from NE Pacific to Europe. However, the SNP panel unexpectedly revealed two additional distinct genetic origins of introductions. Also, conversely to scenarios based on historical records, southern rather than northern NE Pacific populations could have seeded most of the European populations. Finally, the most recently introduced populations showed the lowest selfing rates, suggesting higher levels of recombination might be beneficial at the early stage of the introduction process (i.e., facilitating evolutionary novelties), whereas uniparental reproduction might be favored later in sustainably established populations (i.e., sustaining local adaptation).Agence Nationale de la Recherche - ANR-10-BTBR-04; European Regional Development Fund; Fundacao para a Ciencia e a Tecnologia - SFRH/BPD/107878/2015, UID/Multi/04326/2016, UID/Multi/04326/2019; Brittany Region;info:eu-repo/semantics/publishedVersio
Minimax Estimation of Nonregular Parameters and Discontinuity in Minimax Risk
When a parameter of interest is nondifferentiable in the probability, the
existing theory of semiparametric efficient estimation is not applicable, as it
does not have an influence function. Song (2014) recently developed a local
asymptotic minimax estimation theory for a parameter that is a
nondifferentiable transform of a regular parameter, where the nondifferentiable
transform is a composite map of a continuous piecewise linear map with a single
kink point and a translation-scale equivariant map. The contribution of this
paper is two fold. First, this paper extends the local asymptotic minimax
theory to nondifferentiable transforms that are a composite map of a Lipschitz
continuous map having a finite set of nondifferentiability points and a
translation-scale equivariant map. Second, this paper investigates the
discontinuity of the local asymptotic minimax risk in the true probability and
shows that the proposed estimator remains to be optimal even when the risk is
locally robustified not only over the scores at the true probability, but also
over the true probability itself. However, the local robustification does not
resolve the issue of discontinuity in the local asymptotic minimax risk
Core–sheath polymer nanofiber formation by the simultaneous application of rotation and pressure in a novel purpose-designed vessel
Forming polymeric core–sheath nanofibers is gaining prominence owing to their numerous potential applications, most notably in functional scenarios such as antiviral filtration, which is attracting significant attention due to the current COVID pandemic. This study has successfully designed and constructed a novel pressurized gyration vessel to fabricate core–sheath polymer nanofibers. Several water-soluble and water-insoluble polymer combinations are investigated. Both polyethylene oxide and polyvinyl alcohol were used as the core while both poly(lactic acid) (PLA) and poly(caprolactone) (PCL) were used as the sheath; PLA and PCL were used as core and sheath, in different instances; respectively. The fluid behavior of the core–sheath within the vessel was studied with and without applied pressure using computational fluid dynamics to simulate the core–sheath flow within the chamber. A high-speed camera was used to observe the behavior of jetted solutions at core–sheath openings, and the best scenario was achieved using 6000 rpm spinning speed with 0.2 MPa (twice atmospheric) applied pressure. The surface morphology of core–sheath fibers was studied using a scanning electron microscope, and focused ion beam milling assisted scanning electron microscopy was used to investigate the cross-sectional features of the produced fibers. Laser confocal scanning microscopy was also used to verify the core–sheath structure of the fibers, which were further characterized by Fourier transform infrared spectroscopy and differential scanning calorimetry. Thus, using a variety of polymer combinations, we show, both theoretically and experimentally, how core–sheath fibers evolve in a vessel that can serve as a scalable manufacturing pressurized gyration production process
Experimental and theoretical investigation of the fluid behavior during polymeric fiber formation with and without pressure
The fabrication of polymeric micro/nanofibers is gaining attention due to their use in an array of applications including tissue engineering scaffolds, nanosensors, and fiber-reinforced composites. Despite their versatile nature, polymeric fibers are widely underutilized due to the lack of reliable, large-scale production techniques. Upon the discovery of centrifugal spinning and, recently, pressurized gyration techniques, new research directions have emerged. Here, we report a comprehensive study detailing the optimal conditions to significantly improve the morphology, homogeneity, and yield of fibers of varying diameters. A series of polymeric fibers was created using a 21 wt. % solution of polyethylene oxide in distilled water and the fluid behavior was monitored inside a transparent reservoir using a high-speed camera. Fabrication of the fibers took less than 1 s. Using centrifugal spinning, we studied the formation of the fibers at three different rotational speeds, and for pressurized gyration, one rotational speed was studied with three different nitrogen gas pressures. Using the pressurized gyration technique at a gas pressure of 0.3 MPa, there was significant improvement in the production yield of the fibers. We found a strong correlation between the variation of pressure and the rate of the solution leaving the reservoir with the improved morphology of the fibers. The use of reduced power techniques, like centrifugal spinning and pressured gyration, to yield high-quality nonwoven nanofibers and microfibers in large quantities is important due to their use in rapidly expanding markets
A novel reusable anti-COVID-19 transparent face respirator with optimized airflow
This novel face mask is designed to be a reusable respirator with a small and highly efficient disposable fabric filter. Respirator material requirements are reduced by 75% compared to traditional designs and allow repeated cleaning or sterilization. The probability of virus particle inhalation is reduced using novel air filtration pathways, through square-waveform design to increase filter airflow. Air enters the mask from right and left side filters, while the area in front of the mouth is isolated. Clear epoxy is used for a transparent frame, allowing lip-reading, and mask edges contain a silicone seal preventing bypass of the filters. The mask is manufactured using silicone molds, eliminating electricity requirements making it economical and viable in developing countries. Computational fluid dynamics numerical studies and Fluent ANSYS software were used to simulate airflow through the filter to optimize filter air path geometry and validate mask design with realistic human requirements. The breathing cycle was represented as a transient function, and N95 filter specifications were selected as a porous medium. The novel design achieved 1.2 × 10-3 kg s-1, 20% higher than human requirements, with air streamlines velocity indicating local high speed, forcing and trapping virus particles against filter walls through centrifugal forces
Bilvideo-7: an MPEG-7- compatible video indexing and retrieval system
Cataloged from PDF version of article.BilVideo-7 is an MPEG-7-compatible, distributed, video indexing and retrieval system that supports complex multimodal queries in a unified framework
Adaptive Alert Management for Balancing Optimal Performance among Distributed CSOCs using Reinforcement Learning
Large organizations typically have Cybersecurity Operations Centers (CSOCs) distributed at multiple locations that are independently managed, and they have their own cybersecurity analyst workforce. Under normal operating conditions, the CSOC locations are ideally staffed such that the alerts generated from the sensors in a work-shift are thoroughly investigated by the scheduled analysts in a timely manner. Unfortunately, when adverse events such as increase in alert arrival rates or alert investigation rates occur, alerts have to wait for a longer duration for analyst investigation, which poses a direct risk to organizations. Hence, our research objective is to mitigate the impact of the adverse events by dynamically and autonomously re-allocating alerts to other location(s) such that the performances of all the CSOC locations remain balanced. This is achieved through the development of a novel centralized adaptive decision support system whose task is to re-allocate alerts from the affected locations to other locations. This re-allocation decision is non-trivial because the following must be determined: (1) timing of a re-allocation decision, (2) number of alerts to be re-allocated, and (3) selection of the locations to which the alerts must be distributed. The centralized decision-maker (henceforth referred to as agent) continuously monitors and controls the level of operational effectiveness-LOE (a quantified performance metric) of all the locations. The agent's decision-making framework is based on the principles of stochastic dynamic programming and is solved using reinforcement learning (RL). In the experiments, the RL approach is compared with both rule-based and load balancing strategies. By simulating real-world scenarios, learning the best decisions for the agent, and applying the decisions on sample realizations of the CSOC's daily operation, the results show that the RL agent outperforms both approaches by generating (near-) optimal decisions that maintain a balanced LOE among the CSOC locations. Furthermore, the scalability experiments highlight the practicality of adapting the method to a large number of CSOC locations
Optimization of Process-Control Parameters for the Diameter of Electrospun Hydrophilic Polymeric Composite Nanofibers
A composite nanofiber composed of three polymers, namely polyvinyl alcohol/polyvinyl pyrrolidone/polyethylene oxide, is produced. The experiments are constructed using three design of experiment techniques, Taguchi L9, Taguchi L27, and Screening method. The experiments are verified using the analysis of variance (ANOVA) method and later a mathematical model is developed using the regression method. The impact of electrospun processing parameters, namely applied voltage, flow rate, and working distance, on nanofibers' diameter is measured. The working distance is a significant factor in controlling the size of the fiber diameter, while the applied voltage has the lowest effect on it. As a result of the regression equation, a Genetic algorithm is used to find the optimum variables for the required fiber diameter, which is 156 nm for flow rate = 0.001 mL h−1, voltage = 30 kV, and distance = 200 mm with a 3% difference from the experimental fiber diameter
A Carleman-Picard approach for reconstructing zero-order coefficients in parabolic equations with limited data
We propose a globally convergent computational technique for the nonlinear
inverse problem of reconstructing the zero-order coefficient in a parabolic
equation using partial boundary data. This technique is called the "reduced
dimensional method". Initially, we use the polynomial-exponential basis to
approximate the inverse problem as a system of 1D nonlinear equations. We then
employ a Picard iteration based on the quasi-reversibility method and a
Carleman weight function. We will rigorously prove that the sequence derived
from this iteration converges to the accurate solution for that 1D system
without requesting a good initial guess of the true solution. The key tool for
the proof is a Carleman estimate. We will also show some numerical examples
Simulating the Multi-Epoch Direct Detection Technique to Isolate the Thermal Emission of the Non-Transiting Hot Jupiter HD187123B
We report the 6.5 detection of water from the hot Jupiter HD187123b
with a Keplerian orbital velocity of 53 13 km/s. This high
confidence detection is made using a multi-epoch, high resolution, cross
correlation technique, and corresponds to a planetary mass of
1.4 and an orbital inclination of 21 5.
The technique works by treating the planet/star system as a spectroscopic
binary and obtaining high signal-to-noise, high resolution observations at
multiple points across the planet's orbit to constrain the system's binary
dynamical motion. All together, seven epochs of Keck/NIRSPEC -band
observations were obtained, with five before the instrument upgrade and two
after. Using high resolution SCARLET planetary and PHOENIX stellar spectral
models, along with a line-by-line telluric absorption model, we were able to
drastically increase the confidence of the detection by running simulations
that could reproduce, and thus remove, the non-random structured noise in the
final likelihood space well. The ability to predict multi-epoch results will be
extremely useful for furthering the technique. Here, we use these simulations
to compare three different approaches to combining the cross correlations of
high resolution spectra and find that the Zucker 2003 log(L) approach is least
affected by unwanted planet/star correlation for our HD187123 data set.
Furthermore, we find that the same total S/N spread across an orbit in many,
lower S/N epochs rather than fewer, higher S/N epochs could provide a more
efficient detection. This work provides a necessary validation of multi-epoch
simulations which can be used to guide future observations and will be key to
studying the atmospheres of further separated, non-transiting exoplanets.Comment: Accepted to AJ, 14 pages, 10 figure
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