Fluorescent chitosan-based nanohydrogels and encapsulation of gadolinium MRI contrast agents for magneto-optical imaging

peer reviewedNANOPARTICULES D'OXYDE DE FER OU DE MANGANÈSE DENDRONISÉES POUR L'IRM - Fédération Wallonie Bruxelle

Multimodal nanogels combining ZW800-1 as an optical absorber and gadolinium chelates for multispectral optoacoustic tomography (MSOT) and magnetic resonance imaging (MRI) »

peer reviewe

Progress Report on Target Development

The present document is the D08 deliverable report of work package 1 (Target Development) from the MEGAPIE TEST project of the 5th European Framework Program. Deliverable D08 is the progress report on the activities performed within WP 1. The due date of this deliverable was the 5th month after the start of the EU project. This coincided with a technical status meeting of the MEGAPIE Initiative, that was held in March 2002 in Bologna (Italy). The content of the present document reflects the status of the MEGAPIE target development at that stage. It gives an overview of the Target Design, the related Design Support activities and the progress of the work done for the safety assessment and licensing of the target

Achieving coherence between the Marine Strategy Framework Directive and the Maritime Spatial Planning Directive

Alignment and coordination of the Marine Strategy Framework Directive (MSFD) with other key policies is considered indispensable to accomplish its objectives. To ensure that economic activities do not generate unsustainable pressures in the marine environment, it is imperative to streamline the MSFD with the Maritime Spatial Planning Directive (MSPD), the policy regulating the spatial dimension of maritime activities and their planning. To investigate the coherence between the MSFD and MSPD, an analysis was performed in the framework of MEDREGION project (11.0661/2018/794286/SUB/ENV.C2) on the conceptual relations of the two processes. The needs and challenges encountered by MSFD Competent Authorities (CAs) in the implementation of the Directives were considered, while the Programmes of Measures (PoMs) established by Mediterranean Member States (MSs) for selected MSFD Descriptors were analysed to see whether measures can contribute to the integration of the two Directives. The MSPD implementation considers the MSFD provisions, however, there are still challenges and gaps for an effective integration. Herein, recommendations are made to face these challenges and facilitate the alignment of the two Directives. Moreover, the analysis of the MSFD PoMs shows that the MSFD identifies, directly or indirectly, human activities related to Maritime Spatial Planning (MSP) sectors and addresses them with specific measures. Therefore, MSFD PoMs constitute a concrete basis for the planning of the marine space, thus, bridging the two Directives, avoiding conflicts and facilitating synergies.The research leading to these results has received funding from the European Commission Directorate General for the Environment under grant agreement n° 11.0661/2018/794286/SUB/ENV.C2 – MEDREGION project (Support Mediterranean Member States towards implementation of the MSFD New GES Decision and programmes of measures and contribute to regional/subregional cooperation).Peer reviewe

Labor-Market Performance in the OECD: An Assessment of Recent Evidence

In this paper we assess the evolution of labor-market performance in the Organisation for Economic Co-operation and Development (OECD) over the last decade. We provide a survey of the literature dealing with labor-market performance in the OECD, finding that, while this literature tends to conclude that institutions are a key part of the story, the survey's results appear far less robust and uniform than is commonly believed. We then assess the robustness of the claims made in the most recent (2005) OECD followup study within a very similar cross-country setup, and highlight the impact of unobserved heterogeneity and outliers on the policy estimates. We find that in recent OECD cross-country data, changes in labor-market performance are consistently (and inversely) linked to its lagged level. Structural changes are also important: changes in the share of construction employees are very significant, even in the presence of various kinds of policy change indicators. As far as the latter are concerned, some consistent role seems to emerge only for active labor-market policies and (to a lesser extent) unemployment benefit reforms

Nociceptors: a phylogenetic view

The ability to react to environmental change is crucial for the survival of an organism and an essential prerequisite is the capacity to detect and respond to aversive stimuli. The importance of having an inbuilt “detect and protect” system is illustrated by the fact that most animals have dedicated sensory afferents which respond to noxious stimuli called nociceptors. Should injury occur there is often sensitization, whereby increased nociceptor sensitivity and/or plasticity of nociceptor-related neural circuits acts as a protection mechanism for the afflicted body part. Studying nociception and nociceptors in different model organisms has demonstrated that there are similarities from invertebrates right through to humans. The development of technology to genetically manipulate organisms, especially mice, has led to an understanding of some of the key molecular players in nociceptor function. This review will focus on what is known about nociceptors throughout the Animalia kingdom and what similarities exist across phyla; especially at the molecular level of ion channels

A MSFD complementary approach for the assessment of pressures, knowledge and data gaps in Southern European Seas : the PERSEUS experience

PERSEUS project aims to identify the most relevant pressures exerted on the ecosystems of the Southern European Seas (SES), highlighting knowledge and data gaps that endanger the achievement of SES Good Environmental Status (GES) as mandated by the Marine Strategy Framework Directive (MSFD). A complementary approach has been adopted, by a meta-analysis of existing literature on pressure/impact/knowledge gaps summarized in tables related to the MSFD descriptors, discriminating open waters from coastal areas. A comparative assessment of the Initial Assessments (IAs) for five SES countries has been also independently performed. The comparison between meta-analysis results and IAs shows similarities for coastal areas only. Major knowledge gaps have been detected for the biodiversity, marine food web, marine litter and underwater noise descriptors. The meta-analysis also allowed the identification of additional research themes targeting research topics that are requested to the achievement of GES. 2015 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license.peer-reviewe

Ferrotoroidic ground state in a heterometallic {Cr^IIIDy^III<inf>6</inf>} complex displaying slow magnetic relaxation

© 2017 The Author(s). Toroidal quantum states are most promising for building quantum computing and information storage devices, as they are insensitive to homogeneous magnetic fields, but interact with charge and spin currents, allowing this moment to be manipulated purely by electrical means. Coupling molecular toroids into larger toroidal moments via ferrotoroidic interactions can be pivotal not only to enhance ground state toroidicity, but also to develop materials displaying ferrotoroidic ordered phases, which sustain linear magneto-electric coupling and multiferroic behavior. However, engineering ferrotoroidic coupling is known to be a challenging task. Here we have isolated a {CrIIIDyIII6} complex that exhibits the much sought-after ferrotoroidic ground state with an enhanced toroidal moment, solely arising from intramolecular dipolar interactions. Moreover, a theoretical analysis of the observed sub-Kelvin zero-field hysteretic spin dynamics of {CrIIIDyIII6} reveals the pivotal role played by ferrotoroidic states in slowing down the magnetic relaxation, in spite of large calculated single-ion quantum tunneling rates

Implementation and Performance Evaluation of a Home Network Platform with QoS support

As the number of broadband residential connections is growing very rapidly around the globe, more and more people are looking for a simple and easy way to connect their different home devices to the broadband connection. Home networks are a simple evolution of the office LAN networks that answer the need for residential distribution of broadband services. Unlike the office, home networks have to be at a very low cost and easy to install and maintain. This paper presents the Home Network architectural model defined in the European IST ePerSpace project1 based on a centralized Residential Gateway (RG) connecting and coordinating different network technologies to support home data services. Emphasis is given to testing and evaluating simple but effective mechanisms to support different flows in the home, each with given priorities and Quality of Service (QoS) characteristics. Performance results derived in the measurement campaign are shown and discussed. The prioritization mechanism in the RG results simple to be implemented and effective in achieving the desired flow differentiation and QoS