Gravity duals of 2d supersymmetric gauge theories

We find new supergravity solutions generated by D5-branes wrapping a four-cycle and preserving four and two supersymmetries. We first consider the configuration in which the fivebranes wrap a four-cycle in a Calabi-Yau threefold, which preserves four supersymmetries and is a gravity dual to the Coulomb branch of two-dimensional gauge theories with N=(2,2) supersymmetry. We also study the case of fivebranes wrapping a co-associative four-cycle in a manifold of G_2-holonomy, which provides a gravity dual of N=(1,1) supersymmetric Yang-Mills theory in two dimensions. We also discuss the addition of unquenched fundamental matter fields to these backgrounds and find the corresponding gravity solutions with flavor brane sources.Comment: 34 pages + appendices; v2: minor improvement

A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm

The SR proteins constitute a large family of nuclear phosphoproteins required for constitutive pre-mRNA splicing. These factors also have global, concentration-dependent effects on alternative splicing regulation and this activity is antagonized by members of the hnRNP A/B family of proteins. We show here that whereas some human SR proteins are confined to the nucleus, three of them-SF2/ASF, SRp20, and 9G8-shuttle rapidly and continuously between the nucleus and the cytoplasm. By swapping the corresponding domains between shuttling and nonshuttling SR proteins, we show that the carboxy-terminal arginine/serine-rich (RS) domain is required for shuttling. This domain, however, is not sufficient to promote shuttling of an unrelated protein reporter, suggesting that stable RNA binding mediated by the RNA-recognition motifs may be required for shuttling. Consistent with such a requirement, a double point-mutation in RRM1 of SF2/ASF that impairs RNA binding prevents the protein from shuttling. In addition, we show that phosphorylation of the RS domain affects the shuttling properties of SR proteins. These findings show that different SR proteins have unique intracellular transport properties and suggest that the family members that shuttle may have roles not only in nuclear pre-mRNA splicing but also in mRNA transport, cytoplasmic events, and/or processes that involve communication between the nucleus and the cytoplasm

The inner environment of Z~CMa: High-Contrast Imaging Polarimetry with NaCo

Context. Z\,CMa is a binary composed of an embedded Herbig Be and an FU Ori class star separated by $\sim100$ au. Observational evidence indicate a complex environment in which each star has a circumstellar disk and drives a jet, and the whole system is embedded in a large dusty envelope. Aims. We aim to probe the circumbinary environment of Z\,CMa in the inner 400 au in scattered light. Methods. We use high contrast imaging polarimetry with VLT/NaCo at $H$ and $K_s$ bands. Results. The central binary is resolved in both bands. The polarized images show three bright and complex structures: a common dust envelope, a sharp extended feature previously reported in direct light, and an intriguing bright clump located 0\farcs3 south of the binary, which appears spatially connected to the sharp extended feature. Conclusions.We detect orbital motion when compared to previous observations, and report a new outburst driven by the Herbig star. Our observations reveal the complex inner environment of Z\,CMa with unprecedented detail and contrast.Comment: Accepted for publication in A&A Letter

New Supergravity Backgrounds Dual to N=1 SQCD-like Theories with N_f=2N_c

We present new supergravity backgrounds generated by N_c D5-branes, wrapping the S^2 of the resolved conifold, in the presence of N_f = 2 N_c smeared flavor D5-branes. The smearing allows us to take their backreaction on the geometry into account. We discuss the consistency, stability, and supersymmetry of these types of setups. We find near horizon geometries that we expect to be supergravity duals of SQCD-like theories with N_f= 2N_c. From these backgrounds we numerically extract rectangular Wilson loops and beta functions of the dual field theory for the regime where our approximations are valid.Comment: 22+24 pages, 17 figures, Figure 12 replace

Diagnostico del estado actual de consevación de Puya raimondii en Arequipa – Perù.

The diagnosis of the current state of conservation of Puya raimondii Hams in Arequipa, Perú. – The authors show the results of a survey carried out in Perù, Arequipe region, and Bolivia, on the geographical distribution of Puya raimondii Harms. After describing the systematic and nomenclature of the Andinian species, the study of the biological, ecological and conservation status of this endemic plant species has been performed, as well. They have also described the density population and the risk of genetic erosion caused of both natural and anthropic pressure. Finally they evaluated the use of this plant species as animal feeding, popular medicine traditional local use

Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors

The SR proteins are essential metazoan pre-mRNA splicing factors that can also influence the selection of alternative 5' splice sites in a concentration-dependent manner. Their activity in alternative splicing in vitro is antagonized by members of the hnRNP A/B family of proteins. The opposite effects of members of these two families of antagonistic splicing factors in vitro and upon overexpression in vivo suggest that changes in their relative levels may be a natural mechanism for the regulation of alternative splicing in vivo. One prediction of this model is that the ratios of these antagonists should vary in different cell types and in other situations in which cellular or viral transcripts are differentially spliced. We raised monoclonal antibodies specific for SFS/ASF and used them to measure the abundance of SFS/ASF protein and its isoforms, its phosphorylation state in vivo and during splicing in vitro, and its association with the spliceosome. SF2/ASF exists predominantly or exclusively in a highly phosphorylated state in vivo in all cell types examined, and unphosphorylated protein was not detectable. Unphosphorylated recombinant SFS/ASF becomes rapidly phosphorylated under splicing conditions in HeLa cell extracts and associates stably with one or more exons of beta-globin pre-mRNA. This interaction appears to persist through the splicing reaction and SF2/ASF remains bound to spliced mRNA. We compared the distribution of SFS/ASF to that of its antagonist, hnRNP Al, in different rat tissues and in immortal and transformed cell lines. We found that the protein levels of these antagonistic splicing factors vary naturally over a very wide range, supporting the notion that changes in the ratio of these proteins can affect alternative splicing of a variety of pre-mRNAs in vivo

Unveiling the intruder deformed 02+^+_2 state in 34^{34}Si

The 0$^+_2$ state in $^{34}$Si has been populated at the {\sc Ganil/Lise3} facility through the $\beta$-decay of a newly discovered 1$^+$ isomer in $^{34}$Al of 26(1) ms half-life. The simultaneous detection of $e^+e^-$ pairs allowed the determination of the excitation energy E(0$^+_2$)=2719(3) keV and the half-life T$_{1/2}$=19.4(7) ns, from which an electric monopole strength of $\rho^2$(E0)=13.0(0.9)$\times10^{-3}$ was deduced. The 2$^+_1$ state is observed to decay both to the 0$^+_1$ ground state and to the newly observed 0$^+_2$ state (via a 607(2) keV transition) with a ratio R(2$^+_1$$\rightarrow0^+_1/2^+_1$$\rightarrow0^+_2$)=1380(717). Gathering all information, a weak mixing with the 0$^+_1$ and a large deformation parameter of $\beta$=0.29(4) are found for the 0$^+_2$ state, in good agreement with shell model calculations using a new {\sc sdpf-u-mix} interaction allowing \textit{np-nh} excitations across the N=20 shell gap.Comment: 5 pages, 3 figures, accepted for publication in Physical Review Letter

The Holographic Dual of 2+1 Dimensional QFTs with N=1 SUSY and Massive Fundamental Flavours

The Maldacena Nastase solution is generalised to include massive fundamental matter through the addition of a flavour profile. This gives a holographic dual to N=1 SYM-CS with massive fundamental matter with a singularity free IR. We study this solution in some detail confirming confinement and asymptotic freedom. A recently proposed solution generating technique is then applied which results in a new type-IIA supergravity solution. In a certain limit the geometry of this solution is asymptotically AdS_4X Y, where Y is the metric at the base of the Bryant-Salamon G_2 cone, which has topology S^3XS^3.Comment: 31 pages plus appendices, 6 figures. v3: Typos corrected, version to appear in JHE

No-Drag String Configurations for Steadily Moving Quark-Antiquark Pairs in a Thermal Bath

We investigate the behavior of stationary string configurations on a five-dimensional AdS black hole background which correspond to quark-antiquark pairs steadily moving in an N=4 super Yang-Mills thermal bath. There are many branches of solutions, depending on the quark velocity and separation as well as on whether Euclidean or Lorentzian configurations are examined.Comment: references added; statements corrected; eliminated computation of jet quenching parameter from Wilson loop of [Liu, Rajagopal, Wiedemann, hep-th/0605178] using Euclidean string configurations since those authors advocate [hep-th/0607062, footnote 14] the use of spacelike Lorentzian string configurations instea