Prevalencia de Acinetobacter baumanii en pacientes ingresados en las salas de hospitalización del hospital Alemán Nicaragüense en el departamento de Managua en el periodo de enero a octubre del año 2019

Esta investigación es de tipo descriptivo de corte transversal, con un muestreo aleatorio simple, y que cumple con los criterios de inclusión y exclusión establecidos, se llevó a cabo en los meses de enero del 2019 a octubre del 2019, aplicada en las salas de hospitalización del Hospital Alemán Nicaragüense del departamento de Managua. La población fue de 53 pacientes que fueron ingresadas en dicha institución, de las cuales solo 46 cumplían con los criterios de inclusión correspondientes. Cada uno de los datos fueron recopilados a través de una ficha de recolección de datos que sirvió de instrumento para poder recolectar toda la información necesaria para realizar dicho estudio y cumplir con los objetivos establecidos. Objetivo: este estudio se realizó con el objetivo principal de determinar la prevalencia de Acinetobacter baumanii en pacientes ingresados en las salas de hospitalización del hospital Alemán Nicaragüense en el departamento de Managua en el periodo de enero a octubre del año 2019. Métodos: para la realización de este trabajo se contó con la información proporcionada por el laboratorio de bacteriología del hospital Alemán Nicaragüense, teniendo como resultado que el 40% de los casos corresponde a los pacientes con sexo desconocido y el sexo femenino con el 37%, en cuanto a las edades se encontró que las edades de 0 meses a 10 años fueron las más afectadas con un 37% y 51 a más con 37%. De igual manera se determinaron las salas más afectadas las cuales destacan: UCI (unidad de cuidados intensivos) con 32%, UCINEO (unidad de cuidados intensivos neonatología) con 17%, NEO (neonatología) con 20%, medicina con 11%. Dentro de las muestras que más se destacaron fueron los hemocultivos con 60%, segundo de las secreciones con 32%. En cuanto a la interpretación de los resultados del antibiograma se encontró la mayor resistencia a los carbapenems, entre ellos al imipenem 37% y meropemen con 4%, betalactamicos como la ceftazidima con 36%, ceftriaxona con 20% y cefotaxieme con 4%, seguido de la familia de las sulfonamidas Trimetropim/sulfametoxazol con 39%. Mostrando en su mayoría mecanismos de resistencia como las carbapenemasas con un 69%

Tren de palabras - La escritura de Fernando del Paso

Tren de palabras. La escritura de Fernando del Paso recoge seis ensayos y una entrevista a cargo de cuatro estudiosos de la obra delpasiana; el sello es alumbrar nuevas perspectivas, encarar las omisiones y acrecentar el diálogo, bien argumentado, que abone a una comprensión mejor de esta abrumadora y desbordante literatura, ínsula en sí misma.Universidad Autónoma del Estado de México, UAEM

Determine the Association of Trauma to the Head with the Level of Alcoholemia in Patients Admitted to the Emergency Service of HGZ 3 Tuxtepec Oaxaca

El traumatismo cráneo cefálico es de los principales problemas de salud a nivel mundial, con más frecuencia en varones jóvenes y accidentes de tránsito, siendo la primera causa de muerte en menores de 45 años. Es vital la evaluación neurológica, utilizando la escala de coma de Glasgow, clasifica al trauma en tres grupos de acuerdo con el puntaje. La TAC, es un estudio de neuroimagen que caracteriza a las lesiones cerebrales potencialmente mortales con los hallazgos obtenidos. Debido a la magnitud que representa el TCE es preciso direccionar todo esfuerzo en pro de disminuir la morbi-mortalidad, y evitar en lo más posible las secuelas que pudieran presentar, para ello es necesario establecer un diagnóstico precoz y un manejo oportuno. Objetivos: Analizar si existe asociación del trauma cráneo cefálico en los pacientes con consumo de alcohol, atendidos en el servicio de Urgencias del Hospital general de zona número 3. Material Y metodos: El método utilizado es Prospectivo Casos y Controles, Cuantitativo, Observacional de campo, No experimental. Aplicado a un universo total de pacientes con traumatismo cráneo encefálico y aliento alcohólico que se presenten al servicio de urgencias. Resultados: Se analizaron un total de 120 pacientes que cumplieron con los criterios de inclusión realizándoles la prueba de alcoholemia en sangre, con los resultados de dicha muestra, se identificó que existe asociación del consumo de sustancias alcohólicas con el riesgo de presentar un TCE moderado a severo, con mayor predominio en accidentes de tránsito en vehículos de motor, con mayor frecuencia en el sexo masculino en una edad de 25-59 años. Conclusiones: Se observo que el TCE aunado con la ingesta de alcohol, denota la principal causa de accidentes de tránsito, afectando así a una parte de la población joven económicamente activa entre la edad de 25-59 años, predominio en sexo masculino.  Head trauma is one of the main health problems worldwide, most frequently in young men and traffic accidents, and is the first cause of death in those under 45 years of age. Neurological evaluation is vital, using the Glasgow Coma Scale, classifying trauma into three groups according to the score. CT is a neuroimaging study that characterizes potentially fatal brain lesions with the findings obtained. Due to the magnitude that TBI represents, it is necessary to direct all efforts towards reducing morbidity and mortality, and avoiding as much as possible the consequences that may occur. To do so, it is necessary to establish an early diagnosis and timely management. OBJECTIVES: To analyze whether there is an association of craniocerebral trauma in patients with alcohol consumption, treated in the Emergency Department of the General Hospital of zone number 3. MATERIAL AND METHODS: The method used is Prospective Cases and Controls, Quantitative, Field Observational , Not experimental. Applied to a total universe of patients with head trauma and alcoholic breath who present to the emergency department. RESULTS: A total of 120 patients who met the inclusion criteria were analyzed by performing a blood alcohol test. With the results of said sample, it was identified that there is an association between the consumption of alcoholic substances and the risk of presenting a moderate to TBI. severe, with a greater predominance in traffic accidents in motor vehicles, more frequently in males at an age of 25-59 years. CONCLUSIONS: It was observed that TBI combined with alcohol intake denotes the main cause of traffic accidents, thus affecting a part of the economically active young population between the age of 25-59 years, predominance in males. &nbsp

Phenolic profile and physicochemical characterization of quince (Cydonia oblonga Mill) fruits at different maturity index

The ripening of fruits is a determinant factor on the composition of phytochemical compounds such as phenolic compounds. In this study the phenolic profile of quince fruits was determined as a function of its maturity index. Based on the total soluble solids (TSS) and the acidity (TA) of the fruits, four maturity indexes were established (12.55, 14.56, 21.86 and 24.77), using the ratio of TSS/TA. The phenolic profile of quince fruits with different maturity indexes were obtained by a reversed-phase HPLC-DAD and HPLC-DAD/MS. A PCA loading plot was generated to explain the relationship between physicochemical parameters and the phenolic compounds. The phenolic compounds identified in the quince fruits were 3-0-caffeoylquinic acid, catechin, 4-0-caffeoylquinic acid, 5-0-caffeoylquinic acid, coumaric acid, quercetin-3-0-rutinoside and quercetin-3-0-glycosides. The maturity index increase caused in general a reduction of phenolic compounds, these compounds were also influenced by pH and acidity of fruits. Quince is a valuable source of natural phenolic antioxidants, and can be used as raw material to elaborate diverse food products, providing important functional properties

Informe de monitoreo de ruido ambiental realizado el 6 y 7 de julio de 2015 en los distritos de Arequipa, José Luis Bustamante y Rivera, Cerro Colorado y Cayma, provincia y departamento de Arequipa

Presenta los resultados obtenidos de la medición de ruido ambiental realizado el 6 y 7 de julio en los distritos de Arequipa, José Luis Bustamante y Rivera, Cerro Colorado y Cayma, provincia y departamento de Arequipa. Evalúa el nivel de presión sonora en diez (10) puntos de medición ubicados en dichos distritos; y realizar la comparación de los resultados con los valores establecidos en el Reglamento de Estándares Nacionales de Calidad Ambiental para Ruido, aprobado mediante Decreto Supremo W 085-2003-PCM. Entre sus conclusiones menciona que en las Zonas Comerciales, el 1 00% de los puntos de medición excedieron el valor establecido en los ECA para Ruido, registrándose el valor más alto del LAeq, T en el punto de medición 040129,RUI-02 (74,9 dBA). Por otro lado, el valor más bajo del LAeq,T se registró en el punto de medición 040129,RUI-01 (71, 1 dBA), ambos puntos localizados en el distrito de José Luis Bustamante y Rivera

Physicochemical Quality, Antioxidant Capacity and Nutritional Value in Tuberous Roots of Some Wild Dahlia Species

The aim of this research was to evaluate the physicochemical quality, antioxidant capacity and nutritional value in tuberous roots of some wild dahlia species. The experiment was carried out in the Department of Plant Science of the Autonomous University Chapingo, Mexico. Plants were established in a randomized complete block design with five replications. The total soluble solids (TSS), titratable acidity (TA), vitamin C (VC), total phenols (TP), antioxidant capacity (AC), inulin and its proximate composition were evaluated. Among the materials analyzed, the most outstanding wild species were Dahlia campanulata, D. coccinea and D. brevis, where D. campanulata stood out for its concentration of VC (0.05 mg 100 g-1), AC (1.88 mg VCEAC g-1), inulin, DM and TC (72.25, 24.38 and 88.37%, respectively), however, the inulin content was similar to D. coccinea (66.17%), which was also outstanding with respect to the content of TP (1.74 mg GA g-1). Likewise, D. brevis presented the highest values of RFi (5.49%) and A (78.42%). According to our results, the tuberous roots of wild dahlia species can be used as food, as well as being a source of selection of traits of nutraceutic interest for genetic improvement

Phenolic profile and physicochemical characterization of quince (Cydonia oblonga Mill) fruits at different maturity index

The ripening of fruits is a determinant factor on the composition of phytochemical compounds such as phenolic compounds. In this study the phenolic profile of quince fruits was determined as a function of its maturity index. Based on the total soluble solids (TSS) and the acidity (TA) of the fruits, four maturity indexes were established (12.55, 14.56, 21.86 and 24.77), using the ratio of TSS/TA. The phenolic profile of quince fruits with different maturity indexes were obtained by a reversed-phase HPLC-DAD and HPLC-DAD/MS. A PCA loading plot was generated to explain the relationship between physicochemical parameters and the phenolic compounds. The phenolic compounds identified in the quince fruits were 3-0-caffeoylquinic acid, catechin, 4-0-caffeoylquinic acid, 5-0-caffeoylquinic acid, coumaric acid, quercetin-3-0-rutinoside and quercetin-3-0-glycosides. The maturity index increase caused in general a reduction of phenolic compounds, these compounds were also influenced by pH and acidity of fruits. Quince is a valuable source of natural phenolic antioxidants, and can be used as raw material to elaborate diverse food products, providing important functional properties

Construction and characterization of a double mutant of Enterococcus faecalis that does not produce biogenic amines

Enterococcus faecalis is a lactic acid bacterium characterized by its tolerance of very diverse environmental conditions, a property that allows it to colonize many different habitats. This species can be found in food products, especially in fermented foods where it plays an important role as a biopreservative and influences the development of organoleptic characteristics. However, E. faecalis also produces the biogenic amines tyramine and putrescine. The consumption of food with high concentrations of these compounds can cause health problems. The present work reports the construction, via homologous recombination, of a double mutant of E. faecalis in which the clusters involved in tyramine and putrescine synthesis (which are located in different regions of the chromosome) are no longer present. Analyses showed the double mutant to grow and adhere to intestinal cells normally, and that the elimination of genes involved in the production of tyramine and putrescine has no effect on the expression of other genes

Obstetric outcomes of sars-cov-2 infection in asymptomatic pregnant women

Altres ajuts: Fondo Europeo de Desarrollo Regional (FEDER)Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if SARS-CoV-2 infection at delivery among asymptomatic mothers had different obstetric outcomes compared to negative patients. This was a multicenter prospective study based on universal antenatal screening for SARS-CoV-2 infection. A total of 42 hospitals tested women admitted for delivery using polymerase chain reaction, from March to May 2020. We included positive mothers and a sample of negative mothers asymptomatic throughout the antenatal period, with 6-week postpartum follow-up. Association between SARS-CoV-2 and obstetric outcomes was evaluated by multivariate logistic regression analyses. In total, 174 asymptomatic SARS-CoV-2 positive pregnancies were compared with 430 asymptomatic negative pregnancies. No differences were observed between both groups in key maternal and neonatal outcomes at delivery and follow-up, with the exception of prelabor rupture of membranes at term (adjusted odds ratio 1.88, 95% confidence interval 1.13-3.11; p = 0.015). Asymptomatic SARS-CoV-2 positive mothers have higher odds of prelabor rupture of membranes at term, without an increase in perinatal complications, compared to negative mothers. Pregnant women testing positive for SARS-CoV-2 at admission for delivery should be reassured by their healthcare workers in the absence of symptoms