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Why a Single Parallelization Strategy Is Not Enough in Knowledge Bases
We address the problem of parallelizing the evaluation of logic programs in data intensive applications. We argue that the appropriate parallelization strategy for logic-program evaluation depends on the program being evaluated. Therefore, this paper is concerned with the issues of program classification and parallelization strategies. We propose several parallelization strategies based on the concept of data reduction—the original logic program is evaluated by several processors working in parallel, each using only a subset of the database. The strategies differ on the evaluation cost, the overhead of communication and synchronization among processors, and the programs to which they are applicable. In particular, we start our study with pure parallelization, i.e., parallelization without overhead. An interesting class structure of logic programs is demonstrated, when considering amenability to pure parallelization. The relationship to the NC complexity class is demonstrated. Then we propose strategies that do incur an overhead, but are optimal in a sense that will be precisely defined. This paper makes the initial steps towards a theory of parallel logic programming
“You Need to Set a Daily Schedule”: Understanding Successful Aging via Three-Sided Viewpoints
This study aimed to identify the constructs related to successful aging in the context of engagement in social and productive activities. A qualitative design was used to explore three viewpoints on the aging period with 9 focus groups (3 each for adults 65 years or older, older adults' family members, and health professionals) and 18 interviews with older adults (older adults Mage = 71.7 years, Standard Deviation = 4.62). The transcripts were analyzed using constructivist grounded theory principles. Three categories were identified for successful aging: (a) engagement with life, including social participation, fixed/flexible schedule, time, and meaningful occupation; (b) self-management abilities, including producing daily schedules, independence, and initiation/striving toward goals; and (c) diversity among older adults, including their views on retirement, being active or not, and their dreams/values/goals. Considering the diverse nature of older adults, recognizing the importance of life engagement and self-management abilities emphasizes the necessity for an occupation-based, self-tailored approach to enable successful aging
Location of Emergency Treatment Sites after Earthquake using Hybrid Simulation
A mass-casualty natural disaster such as an earthquake is a rare, surprising event that is usually characterized by chaos and a lack of information, resulting in an overload of casualties in hospitals. Thus, it is very important to refer minor and moderately-injured casualties, that are the majority of casualties and whose injuries are usually not life threatening, to ad hoc care facilities such as Emergency Treatment Sites (ETSs). These facilities support the efficient use of health resources and reduce the burden on permanent healthcare facilities. In our study, a hybrid simulation model, based on a combination of discrete events and an agent-based simulation, provides a solution to the uncertainty of positioning temporary treatment sites. The simulation methodology used compares between "rigid" and "flexible" operating concepts of ETSs (main vs. main+minor ETSs) and found the "flexible" concept to be more efficient in terms of the average walking distance and number of casualties treated in the disaster area
Histoires pragmatiques
Roberto Gronda & Tullio Viola – Your work is frequently referred to as “pragmatic history.” This notion, however, is by no means a new one: Polybius spoke of pragmatikê historia, Germany had pragmatische Geschichte in the tradition of Kantian anthropology. Can you tell us something about how you understand this label, and about your own encounter with “pragmatic history”? Simona Cerutti – Personally, I had quite an idiosyncratic introduction to pragmatic history, although this encounter was n..
The effect of autistic traits on disembedding and mental rotation in neurotypical women and men.
Recent data has revealed dissociations between social and non-social skills in both autistic and neurotypical populations. In the present study, we investigated whether specific visuospatial abilities, such as figure disembedding and mental rotation, are differently related to social and non-social autistic traits, in neurotypical women and men. University students (N = 426) completed the Autism Spectrum Quotient (AQ), figure disembedding and mental rotation of two-dimensional figures tasks. AQ social skills (AQ-social) and attention-to-details (AQ-attention) subscales were used as measures of social and non-social autistic traits, respectively. Mental rotation was affected by a significant interaction between sex, social and non-social traits. When non-social traits were above the mean (+ 1 SD), no sex differences in mental rotation were found. Instead, below this value, sex differences depended on the social traits, with men on average outperforming women at middle-to-high social traits, and with a comparable performance, and with women on average outperforming men, at lower social traits. A small positive correlation between figure disembedding and social traits was observed in the overall sample. These results are interpreted in terms of the hyper-systemizing theory of autism and contribute to the evidence of individual differences in the cognitive style of autistic people and neurotypical people with autistic traits
The ACS Fornax Cluster Survey. IX. The Color-Magnitude Relation of Globular Cluster Systems
We investigate the color-magnitude relation for globular clusters (GCs) --
the so-called "blue tilt" -- detected in the ACS Fornax Cluster Survey and
using the combined sample of GCs from the ACS Fornax and Virgo Cluster Surveys.
We find a tilt of gamma_z=d(g-z)/dz=-0.0257 +- 0.0050 for the full GC sample of
the Fornax Cluster Survey (~5800 GCs). This is slightly shallower than the
value gamma_z=-0.0459 +- 0.0048 found for the Virgo Cluster Survey GC sample
(~11100 GCs). The slope for the merged Fornax and Virgo datasets (~16900 GCs)
is gamma_z=-0.0293 +- 0.0085, corresponding to a mass-metallicity relation of Z
~ M^0.43. We find that the blue tilt sets in at GC masses in excess of M ~
2*10^5 M_sun. The tilt is stronger for GCs belonging to high-mass galaxies (M_*
> 5 * 10^10 M_sun) than for those in low-mass galaxies (M_* < 5 * 10^10 M_sun).
It is also more pronounced for GCs with smaller galactocentric distances. Our
findings suggest a range of mass-metallicity relations Z_GC ~ M_GC^(0.3-0.7)
which vary as a function of host galaxy mass/luminosity. We compare our
observations to a recent model of star cluster self-enrichment with generally
favorable results. We suggest that, within the context of this model, the
proto-cluster clouds out of which the GCs formed may have had density profiles
slightly steeper than isothermal and/or star formation efficiencies somewhat
below 0.3. We caution, however, that the significantly different appearance of
the CMDs defined by the GC systems associated with galaxies of similar mass and
morphological type pose a challenge to any single mechanism that seeks to
explain the blue tilt. We therefore suggest that the merger/accretion histories
of individual galaxies have played a non-negligible role determining the
distribution of GCs in the CMDs of individual GC systems
Statistical Mechanics of Torque Induced Denaturation of DNA
A unifying theory of the denaturation transition of DNA, driven by
temperature T or induced by an external mechanical torque Gamma is presented.
Our model couples the hydrogen-bond opening and the untwisting of the
helicoidal molecular structure. We show that denaturation corresponds to a
first-order phase transition from B-DNA to d-DNA phases and that the
coexistence region is naturally parametrized by the degree of supercoiling
sigma. The denaturation free energy, the temperature dependence of the twist
angle, the phase diagram in the T,Gamma plane and isotherms in the sigma, Gamma
plane are calculated and show a good agreement with experimental data.Comment: 5 pages, 3 figures, model improve
Recurrent radio outbursts at the center of the NGC1407 galaxy group
We present deep Giant Metrewave Radio Telescope (GMRT) radio observations at
240, 330 and 610 MHz of the complex radio source at the center of the NGC1407
galaxy group. Previous GMRT observations at 240 MHz revealed faint, diffuse
emission enclosing the central twin-jet radio galaxy. This has been interpreted
as an indication of two possible radio outbursts occurring at different times.
Both the inner double and diffuse component are detected in the new GMRT images
at high levels of significance. Combining the GMRT observations with archival
Very Large Array data at 1.4 and 4.9 GHz, we derive the total spectrum of both
components. The inner double has a spectral index \alpha=0.7, typical for
active, extended radio galaxies, whereas the spectrum of the large-scale
emission is very steep, with \alpha=1.8 between 240 MHz and 1.4 GHz. The
radiative age of the large-scale component is very long, ~300 Myr, compared to
~30 Myr estimated for the central double, confirming that the diffuse component
was generated during a former cycle of activity of the central galaxy. The
current activity have so far released an energy which is nearly one order of
magnitude lower than that associated with the former outburst. The group X-ray
emission in the Chandra and XMM-Newton images and extended radio emission show
a similar swept-back morphology. We speculate that the two structures are both
affected by the motion of the group core, perhaps due to the core sloshing in
response to a recent encounter with the nearby elliptical galaxy NGC1400.Comment: 15 pages, 12 figures and 5 tables. Accepted for publication in Ap
N-acetylcysteine treatment ameliorates the skeletal phenotype of a mouse model of diastrophic dysplasia
Diastrophic dysplasia (DTD) is a recessive chondrodysplasia caused by mutations in SLC26A2, a cell membrane sulfate-chloride antiporter. Sulfate uptake impairment results in low cytosolic sulfate, leading to cartilage proteoglycan (PG) undersulfation. In this work, we used the dtd mouse model to study the role of N-acetyl-l-cysteine (NAC), a well-known drug with antioxidant properties, as an intracellular sulfate source for macromolecular sulfation. Because of the important pre-natal phase of skeletal development and growth, we administered 30 g/l NAC in the drinking water to pregnant mice to explore a possible transplacental effect on the fetuses. When cartilage PG sulfation was evaluated by high-performance liquid chromatography disaccharide analysis in dtd newborn mice, a marked increase in PG sulfation was observed in newborns from NAC-treated pregnancies when compared with the placebo group. Morphometric studies of the femur, tibia and ilium after skeletal staining with alcian blue and alizarin red indicated a partial rescue of abnormal bone morphology in dtd newborns from treated females, compared with pups from untreated females. The beneficial effect of increased macromolecular sulfation was confirmed by chondrocyte proliferation studies in cryosections of the tibial epiphysis by proliferating cell nuclear antigen immunohistochemistry: the percentage of proliferating cells, significantly reduced in the placebo group, reached normal values in dtd newborns from NAC-treated females. In conclusion, NAC is a useful source of sulfate for macromolecular sulfation in vivo when extracellular sulfate supply is reduced, confirming the potential of therapeutic approaches with thiol compounds to improve skeletal deformity and short stature in human DTD and related disorder
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