Diplomado de Profundización CISCO, Prueba de Habilidades Prácticas CCNP

El presente trabajo se desarrolla como opción de grado para la ingeniería en telecomunicaciones y electrónica , aplicando todas las habilidades prácticas y adquiridas bajo un escenario de CCNP planteado , este escenario se desarrolla en el simulador de GNS3 utilizando y empleando imágenes IOS de los dispositivos de CISCO, el escenario se observa como una propuesta simple sin embargo los requisitos exigidos por la guía son muy diversos para poder lograr simular tal cual la red a nivel profesional :aplicando todas las habilidades adquiridas y conocimientos por el estudiante en las redes de datos configurando así como primera instancia los protocolos para la conmutación en la capa 2 del modelo OSI y paralelamente se configura los protocolos de la capa 3 para establecer el enrutamiento entre la propia LAN (red empresa) y otro sistema autónomo (ISP) obteniendo como resultado redes convergentes que se comunican entre si con políticas de seguridad establecidas simulando escenarios a los cuales se va a enfrentar el futuro egresadoThe present work is developed as a degree option for telecommunications and electronics engineering, applying all the practical and acquired skills under a proposed CCNP scenario, this scenario is developed in the GNS3 simulator using and using IOS images of CISCO devices , the scenario is seen as a simple proposal, however the requirements demanded by the guide are very diverse to be able to simulate the network as it is at a professional level: applying all the skills acquired and knowledge by the student in data networks configuring as well as In the first instance, the protocols for switching in layer 2 of the OSI model and in parallel, the layer 3 protocols are configured to establish routing between the LAN itself (company network) and another autonomous system (ISP), obtaining as a result convergent networks that are communicate with each other with established security policies simulating scenarios to which What will the future graduat

OS VECINOS LUSITANOS NA RESTAURAÇÃO PORTUGUESA: UM ESTUDO DAS REDES SOCIAIS NA BUENOS AIRES SEISCENTISTA

Neste artigo busca-se analisar a construção de estruturas (in)formais de relações pessoais tecidas por portugueses na cidade-porto da Buenos Aires seiscentista, assim como a expansão de suas redes de poder e vinculações na América portuguesa. O ponto central da análise está nas relações conflituosas entre comerciantes portugueses, seus vecinos e as autoridades espanholas que aparecem em fontes como as Atas do Cabildo,documentos comerciais e particulares. Deseja-se mostrar que se faz necessário o estudo destas famílias de vecinos muitas vezes pobres e marginais se comparadas aos grandes centros comerciais e políticos da América colonial, mas não menos importantes para o estudo das construções dos poderes políticos locais na América colonial

Consideraciones Epistemológicas para una Educación Inclusiva más oportuna: la necesidad de un nuevo paradigma epistémico

Este documento analiza las problemáticas fundacionales del enfoque de educación inclusiva y sus repercusiones, en la consolidación de un enfoque de Educación Para Todos (E.P.T.). Se reconoce el desplazamiento de una matriz epistémica del tipo trans-ontológica por sobre los desafíos fundacionales que cruzan la ciencia educativa en general en el marco de la post-modernidad. Inicialmente, se identifica, mediante una observación reflexiva, la transformación de ciertas necesidades sociales y su eficacia simbólica, develando la urgencia de contribuir a sentar las condiciones epistémicas y extra epistémicas más coherentes con los desafíos de asumir la heterogeneidad como parte de un enfoque legitimador de la totalidad humana. Se concluye reconociendo la existencia de un estatus científico hibrido e impreciso en la materia, apuntando a refundar aquellas visiones fundacionales que lo sostienen y evaluando los límites y las limitaciones de aquellos apriorismos en la construcción de saberes pedagógicos oportunos respecto de los desafíos del nuevo siglo

Chiral Ureas and Thioureas Supported on Polystyrene for Enantioselective Aza-Henry Reaction in Solvent-free conditions

Producción CientíficaNovel bifunctional ureas and thioureas inmovilized on sulfonylpystyrene have been prepared as recoverable and reusable organocatalysts and used in the stereoselective aza-Henry reaction under solvent-free conditions. The activity and stereoselection of the catalysts are dependent on the length of the tether bringing the active site and the polymer, being the catalyst derived from 1,6-hexane diamine the best one. It has been also demonstrated that the supported catalysts are more effective than the homologous soluble catalysts.Ministerio de Economía, Industria y Competitividad (CTQ 2011-28487)Junta de Castilla y León (programa de apoyo a proyectos de investigación – Ref. VA064U13

Identification of a field isolate of Fasciola hepatica resistant to albendazole and susceptible to triclabendazole

The experiments described here were designed to characterize the status of susceptibility/resistance to albendazole (ABZ) and triclabendazole (TCBZ) of a Fasciola hepatica isolate (named CEDIVE isolate) recovered from infected sheep (Gualeguay, Argentina) and maintained under laboratory conditions. Two separate clinical efficacy experiments were performed on sheep artificially infected with the CEDIVE isolate. Experiment 1: Sheep were randomly distributed either in an untreated control group or an ABZ (7.5 mg/kg) treated group (n= 4 each). Additionally, the systemic exposure of ABZ metabolites was assessed in those ABZ-treated infected animals. In Experiment 2, an untreated control group and a TCBZ (10 mg/kg) treated group was included (n = 4 each). The fluckicidal efficacy of ABZ and TCBZ was assessed by comparison of the number of flukes recovered from untreated and treated sheep at 15 days post-treatment. The efficacy against the CEDIVE isolate of F. hepatica was 29% (ABZ) and 100% (TCBZ). The plasma drug exposure (expressed as AUC and Cmax) observed in the ABZ treated animals (Experiment 1), was in agreement with data obtained in previous studies, which indicate that the low ABZ efficacy was not related to the quality of the pharmaceutical product and/or to a low systemic availability of the active drug/metabolite. The results reported here, clearly show that the CEDIVE isolate of F. hepatica behaves as resistant to ABZ and susceptible to TCBZ.Fil: Sanabria, Rodrigo Eduardo Fabrizio. Universidad Nacional de la Plata. Facultad de Ciencias Veterinarias; Argentina;Fil: Ceballos, Laura. Universidad Nacional del Centro de la Provincia de Buenos Aires.. Facultad de Ciencias Veterinarias. Departamento de Fisiopatologia. Laboratorio de Farmacologia; Argentina;Fil: Moreno, Laura. Universidad Nacional del Centro de la Provincia de Buenos Aires.. Facultad de Ciencias Veterinarias. Departamento de Fisiopatologia. Laboratorio de Farmacologia; Argentina;Fil: Romero, Jorge Marcelo. Universidad Nacional de la Plata. Facultad de Ciencias Veterinarias; Argentina;Fil: Lanusse Carlos. Universidad Nacional del Centro de la Provincia de Buenos Aires.. Facultad de Ciencias Veterinarias. Departamento de Fisiopatologia. Laboratorio de Farmacologia; Argentina;Fil: Alvarez Luis. Universidad Nacional del Centro de la Provincia de Buenos Aires.. Facultad de Ciencias Veterinarias. Departamento de Fisiopatologia. Laboratorio de Farmacologia; Argentina

Identification of a field isolate of Fasciola hepatica resistant to albendazole and susceptible to triclabendazole

The experiments described here were designed to characterize the status of susceptibility/resistance to albendazole (ABZ) and triclabendazole (TCBZ) of a Fasciola hepatica isolate (named CEDIVE isolate) recovered from infected sheep (Gualeguay, Argentina) and maintained under laboratory conditions. Two separate clinical efficacy experiments were performed on sheep artificially infected with the CEDIVE isolate. Experiment 1: Sheep were randomly distributed either in an untreated control group or an ABZ (7.5 mg/kg) treated group (n= 4 each). Additionally, the systemic exposure of ABZ metabolites was assessed in those ABZ-treated infected animals. In Experiment 2, an untreated control group and a TCBZ (10 mg/kg) treated group was included (n = 4 each). The fluckicidal efficacy of ABZ and TCBZ was assessed by comparison of the number of flukes recovered from untreated and treated sheep at 15 days post-treatment. The efficacy against the CEDIVE isolate of F. hepatica was 29% (ABZ) and 100% (TCBZ). The plasma drug exposure (expressed as AUC and Cmax) observed in the ABZ treated animals (Experiment 1), was in agreement with data obtained in previous studies, which indicate that the low ABZ efficacy was not related to the quality of the pharmaceutical product and/or to a low systemic availability of the active drug/metabolite. The results reported here, clearly show that the CEDIVE isolate of F. hepatica behaves as resistant to ABZ and susceptible to TCBZ.Facultad de Ciencias Veterinaria

Estimating changes in air pollutant levels due to COVID-19 lockdown measures based on a business-as-usual prediction scenario using data mining models: A case-study for urban traffic sites in Spain

In response to the COVID-19 pandemic, governments declared severe restrictions throughout 2020, presenting an unprecedented scenario of reduced anthropogenic emissions of air pollutants derived mainly from traffic sources. To analyze the effect of these restrictions derived from COVID-19 pandemic on air quality levels, relative changes in NO, NO2, O3, PM10 and PM2.5 concentrations were calculated at urban traffic sites in the most populated Spanish cities over different periods with distinct restrictions in 2020. In addition to the changes calculated with respect to the observed air pollutant levels of previous years (2013-2019), relative changes were also calculated using predicted pollutant levels for the different periods over 2020 on a business-as-usual scenario using Multiple Linear Regression (MLR) models with meteorological and seasonal predictors. MLR models were selected among different data mining techniques (MLR, Random Forest (RF), K-Nearest Neighbors (KNN)), based on their higher performance and accuracy obtained from a leave-one-year-out cross-validation scheme using 2013-2019 data. A q-q mapping post-correction was also applied in all cases in order to improve the reliability of the predictions to reproduce the observed distributions and extreme events. This approach allows us to estimate the relative changes in the studied air pollutants only due to COVID-19 restrictions. The results obtained from this approach show a decreasing pattern for NOx, with the largest reduction in the lockdown period above -50%, whereas the increase observed for O3 contrasts with the NOx patterns with a maximum increase of 23.9%. The slight reduction in PM10 (-4.1%) and PM2.5 levels (-2.3%) during lockdown indicates a lower relationship with traffic sources. The developed methodology represents a simple but robust framework for exploratory analysis and intervention detection in air quality studies.This research was developed in the framework of the Project “Contaminación atmosférica y COVID-19: ¿Qué podemos aprender de esta pandemia?”, selected in the Extraordinary BBVA Foundation grant call for SARS-CoV-2 and COVID-19 research proposals, within the area of ecology and veterinary science

Identification of a field isolate of Fasciola hepatica resistant to albendazole and susceptible to triclabendazole

The experiments described here were designed to characterize the status of susceptibility/resistance to albendazole (ABZ) and triclabendazole (TCBZ) of a Fasciola hepatica isolate (named CEDIVE isolate) recovered from infected sheep (Gualeguay, Argentina) and maintained under laboratory conditions. Two separate clinical efficacy experiments were performed on sheep artificially infected with the CEDIVE isolate. Experiment 1: Sheep were randomly distributed either in an untreated control group or an ABZ (7.5 mg/kg) treated group (n= 4 each). Additionally, the systemic exposure of ABZ metabolites was assessed in those ABZ-treated infected animals. In Experiment 2, an untreated control group and a TCBZ (10 mg/kg) treated group was included (n = 4 each). The fluckicidal efficacy of ABZ and TCBZ was assessed by comparison of the number of flukes recovered from untreated and treated sheep at 15 days post-treatment. The efficacy against the CEDIVE isolate of F. hepatica was 29% (ABZ) and 100% (TCBZ). The plasma drug exposure (expressed as AUC and Cmax) observed in the ABZ treated animals (Experiment 1), was in agreement with data obtained in previous studies, which indicate that the low ABZ efficacy was not related to the quality of the pharmaceutical product and/or to a low systemic availability of the active drug/metabolite. The results reported here, clearly show that the CEDIVE isolate of F. hepatica behaves as resistant to ABZ and susceptible to TCBZ.Facultad de Ciencias Veterinaria