Lista atualizada de quirópteros da Amazônia Brasileira

We present an updated checklist on bats of the Amazon Basin in Brazil, based on our collection of 3.081 specimens in 12 areas in the Basin and a review of the existing literature. The list consists of 95 species belonging to 51 genera and 9 families: 3 species (Micronycteris hirsuta, Natalus stramineus and Rhogessa tumida) are being cited for the first time as present in the Amazon Basin; of the remaining 92 species reported by previous workers. 68 were registered and confirmed by the present authors.É apresentada uma lista atualizada de quirópteros da região amazônica brasileira, baseada em nossa coleção de 3.081 exemplares capturados em 12 áreas na Bacia Amazônica e com referência às literaturas anteriormente publicadas. A lista conta com 95 espécies de 51 gêneros e 9 famílias, sendo 3 espécies (Micronycteris hirsuta, Natalus stramineus e Rhogessa tumida) citadas pela primeira vez como ocorrendo na região; e das demais alistadas por pesquisadores anteriores, são registradas e confirmadas 68 espécies

Editorial: immune monitoring responses in renal autoimmune diseases

Nephrolog

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

We carried out a trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up to 320,251 individuals of East Asian, European and South Asian ancestry. We find genetic variants at 12 new loci to be associated with blood pressure (P = 3.9 × 10-11 to 5.0 × 10-21). The sentinel blood pressure SNPs are enriched for association with DNA methylation at multiple nearby CpG sites, suggesting that, at some of the loci identified, DNA methylation may lie on the regulatory pathway linking sequence variation to blood pressure. The sentinel SNPs at the 12 new loci point to genes involved in vascular smooth muscle (IGFBP3, KCNK3, PDE3A and PRDM6) and renal (ARHGAP24, OSR1, SLC22A7 and TBX2) function. The new and known genetic variants predict increased left ventricular mass, circulating levels of NT-proBNP, and cardiovascular and all-cause mortality (P = 0.04 to 8.6 × 10-6). Our results provide new evidence for the role of DNA methylation in blood pressure regulation

Star clusters near and far; tracing star formation across cosmic time

© 2020 Springer-Verlag. The final publication is available at Springer via https://doi.org/10.1007/s11214-020-00690-x.Star clusters are fundamental units of stellar feedback and unique tracers of their host galactic properties. In this review, we will first focus on their constituents, i.e.\ detailed insight into their stellar populations and their surrounding ionised, warm, neutral, and molecular gas. We, then, move beyond the Local Group to review star cluster populations at various evolutionary stages, and in diverse galactic environmental conditions accessible in the local Universe. At high redshift, where conditions for cluster formation and evolution are more extreme, we are only able to observe the integrated light of a handful of objects that we believe will become globular clusters. We therefore discuss how numerical and analytical methods, informed by the observed properties of cluster populations in the local Universe, are used to develop sophisticated simulations potentially capable of disentangling the genetic map of galaxy formation and assembly that is carried by globular cluster populations.Peer reviewedFinal Accepted Versio

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

The elderly with renal disease undergoing kidney biopsy-an opportunity for vaccination?

10.1093/ckj/sfz111Clinical Kidney Journal132263-26

Current and future treatment approaches for neuromyelitis optica

Neuromyelitis optica (NMO) is an inflammatory disease of the central nervous system (CNS) characterized by severe attacks of optic neuritis and myelitis, and which, unlike multiple sclerosis (MS), commonly spares the brain in the early stages. NMO used to be considered as a special form of MS. During the past 10 years, however, the two diseases have been shown to be clearly different. NMO is a B-cell-mediated disease associated with anti-aquaporin-4 antibodies in many cases and its pathophysiology seems to be near the acute lesion of necrotizing vasculitis. Assessment of prevalence shows that NMO is far less frequent than MS, which explains the absence of randomized clinical trials and NMO treatment strategies validated by evidence-based medicine. Recently, many data have been published that suggest that the therapeutic option in NMO should be immunosuppressive rather than immunomodulatory drugs. In the present study, after a brief overview of NMO, we review therapeutic studies and propose new therapeutic strategies in the relapse and disease-modifying fields

Architectures of Mathematics Beliefs: Individual and School-level Differences among Hong Kong Primary 6 Students

Students’ beliefs influence their learning, so teachers can help students learn by cultivating constructive beliefs and amending harmful ones. Teacher influence is likely greater if student beliefs are loosely structured but weaker if student beliefs are coherent and tightly structured. We examined the structure of students’ beliefs by analyzing the questionnaire responses of 2,736 Hong Kong Primary 6 students. Students’ mathematics beliefs about formulas, learning by understanding, usefulness, easiness, and interest showed a strong and stable nested structure. This nested structure included a general factor and specific factors for formula, usefulness, easiness and interest. Individual differences accounted for most of the variation among student beliefs (on average, 92% at the student level and 8% at the school level). Several of these beliefs correlated with gender, tutoring, and time spent doing mathematics homework.link_to_OA_fulltex