Cloud Chamber: A Performance with Real Time Two-Way Interaction between Subatomic Particles and Violinist

‘Cloud Chamber’ - a composition by Alexis Kirke, Antonino Chiaramonte, and Anna Troisi - is a live performance in which the invisible quantum world becomes visible as a violinist and subatomic particle tracks interact together. An electronic instrument was developed which can be “played” live by radioactive atomic particles. Electronic circuitry was developed enabling a violin to create a physical force field that directly affects the ions generated by cosmic radiation particles. This enabled the violinist and the ions to influence each other musically in real time. A glass cloud chamber was used onstage to make radioactivity visible in bright white tracks moving within, with the tracks projected onto a large screen

Identification of the growth arrest and DNA damage protein GADD34 in the normal human heart and demonstration of alterations in expression following myocardial ischaemia

Growth arrest and DNA damage protein 34 (GADD34) is a multifunctional protein upregulated in response to cellular stress and is believed to mediate DNA repair and restore protein synthesis. In the present study we have examined GADD34 immunoreactivity in human myocardial tissue at defined survival times following cardiac arrest and determined alterations in expression following ischaemia. In the normal human heart, GADD34 immunoreactivity was generally intense and present within most cells. GADD34 immunoreactivity was downregulated in tissue displaying ischaemic damage and remained intense in adjacent non-infarcted tissue. Unlike brain, GADD34 was not found to be upregulated in the peri-infarct zone. Cells displaying apoptotic changes were located in regions displaying reduced GADD34 immunoreactivity. In the brain, it is thought that GADD34 supports re-initiation of protein synthesis following ischaemia. Similarly, GADD34 may perform important functions in cardiac tissue in response to ischaemia

The circumstellar environment of T Tau S at high spatial and spectral resolution

We have obtained the first high spatial (0.05'') and spectral (R~35000) resolution 2 micron spectrum of the T Tau S tight binary system using adaptive optics on the Keck II telescope. We have also obtained the first 3.8 and 4.7 micron images that resolve the three components of the T Tau multiple system, as well as new 1.6 and 2.2 micron images. Together with its very red near-infrared colors, the spectrum of T Tau Sb shows that this T Tauri star is extincted by a roughly constant extinction of Av~15 mag, which is probably the 0.7''x0.5'' circumbinary structure recently observed in absorption in the ultraviolet. T Tau Sa, which is also observed through this screen and is actively accreting, further possesses a small edge-on disk that is evidenced by warm (390 K), narrow overtone CO rovibrational absorption features in our spectrum. We find that T Tau Sa is most likely an intermediate-mass star surrounded by a semi-transparent 2-3 AU-radius disk whose asymmetries and short Keplerian rotation explain the large photometric variability of the source on relatively short timescales. We also show that molecular hydrogen emission exclusively arises from the gas that surrounds T Tau S and that its spatial and kinematic structure, while providing suggestive evidence for a jet-like structure, is highly complex.Comment: accepted for publication in the Astrophysical Journal; 41 pages, 10 figure

Extended scope of nursing practice: a multicentre randomised controlled trial of appropriately trained nurses and pre-registration house officers in pre-operative assessment in elective general surgery

Aim/ Principal Research Question:1) To determine whether pre-operative assessment carried out by an appropriately trained nurse (ATN) is equivalent in quality to that carried out by a pre-registration house officer (PRHO).2) To assess whether pre-assessments carried out by ATNs and PRHOs are equivalent in terms of cost.3) To determine whether assessments carried out by ATNs are acceptable to patients.4) To investigate the quality of communication between senior medical staff and ATNs.Factors of Interest:The extended role of appropriately trained nurses and pre-registration house officers in pre-operative assessment in elective general surgery.Methods:The study design was principally a prospective randomised equivalence trial but was accompanied by additional qualitative assessment of patient and staff perceptions, and an economic evaluation.The intervention consisted of a pre-operative assessment carried out by either an ATN or a PRHO. Of the patients who completed the study with a full evaluation, 926 patients were randomised to the PRHO arm of the trial and 948 to the ATN arm. Three ATNs took part in the study, one from each centre, together with a total of 87 PRHOs.Immediately following the initial assessment of a patient by a PRHO or an ATN, one of a number of clinical research fellows, all specialist registrars in anaesthetics, repeated the assessment and recorded it on a study form, together with a list of investigations required. The clinical research fellow then evaluated the competency of the initial assessor by comparing the quality of their assessment with their own. Any deficiencies in ordering of investigations and referral to other specialities were met in order to maximise patient care.Sample groups:All patients attending at one site for assessment prior to general anaesthetic for elective general, vascular, urological or breast surgery were potentially included in the study. Of 1907 patients who were randomised, 1874 completed the study with a full evaluation.The study was carried out at four NHS hospitals, three of which were teaching hospitals, in three NHS Trusts in Southampton, Sheffield and Doncaster.Outcome measures:Three areas of ATN and PRHO performance were judged separately, history taking, examination and ordering of tests, and each was graded into one of four categories, the most important of which was under-assessment, which would possibly have affected peri-operative management. In the case of ordering of tests, it was possible to have both over- and under-assessed a patient on different tests.Findings:The pre-operative assessments carried out by the ATNs were essentially equivalent to those performed by the PRHOs in terms of under-assessment that might possibly have affected peri-operative management, although there was variation between the ATNs in terms of the quality of history taking. This may be related to the low number of patients seen at one study site.PRHOs ordered significantly more unnecessary tests than the ATNs. The substitution of ATNs for PRHOs was calculated to be cost neutral.The results of the qualitative assessment showed that the use of ATNs for pre-operative assessment was acceptable to patients; however, there was no evidence that communication between senior medical staff and those carrying out pre-operative assessments was improved by their introduction.Conclusions:This study demonstrated no reason to inhibit the development of fully nurse-led pre-operative assessment, provided that the nurses are appropriately trained and maintain sufficient workload to retain skills.Implications for Further Research:Further research is needed in the following areas:1) the extent and type of training needed for nurses undertaking the pre-operative assessment role2) the use, costs and benefits of routine pre-operative testing.<br/

The future of Earth observation in hydrology

In just the past 5 years, the field of Earth observation has progressed beyond the offerings of conventional space-agency-based platforms to include a plethora of sensing opportunities afforded by CubeSats, unmanned aerial vehicles (UAVs), and smartphone technologies that are being embraced by both for-profit companies and individual researchers. Over the previous decades, space agency efforts have brought forth well-known and immensely useful satellites such as the Landsat series and the Gravity Research and Climate Experiment (GRACE) system, with costs typically of the order of 1 billion dollars per satellite and with concept-to-launch timelines of the order of 2 decades (for new missions). More recently, the proliferation of smart-phones has helped to miniaturize sensors and energy requirements, facilitating advances in the use of CubeSats that can be launched by the dozens, while providing ultra-high (3-5 m) resolution sensing of the Earth on a daily basis. Start-up companies that did not exist a decade ago now operate more satellites in orbit than any space agency, and at costs that are a mere fraction of traditional satellite missions. With these advances come new space-borne measurements, such as real-time high-definition video for tracking air pollution, storm-cell development, flood propagation, precipitation monitoring, or even for constructing digital surfaces using structure-from-motion techniques. Closer to the surface, measurements from small unmanned drones and tethered balloons have mapped snow depths, floods, and estimated evaporation at sub-metre resolutions, pushing back on spatio-temporal constraints and delivering new process insights. At ground level, precipitation has been measured using signal attenuation between antennae mounted on cell phone towers, while the proliferation of mobile devices has enabled citizen scientists to catalogue photos of environmental conditions, estimate daily average temperatures from battery state, and sense other hydrologically important variables such as channel depths using commercially available wireless devices. Global internet access is being pursued via high-altitude balloons, solar planes, and hundreds of planned satellite launches, providing a means to exploit the "internet of things" as an entirely new measurement domain. Such global access will enable real-time collection of data from billions of smartphones or from remote research platforms. This future will produce petabytes of data that can only be accessed via cloud storage and will require new analytical approaches to interpret. The extent to which today's hydrologic models can usefully ingest such massive data volumes is unclear. Nor is it clear whether this deluge of data will be usefully exploited, either because the measurements are superfluous, inconsistent, not accurate enough, or simply because we lack the capacity to process and analyse them. What is apparent is that the tools and techniques afforded by this array of novel and game-changing sensing platforms present our community with a unique opportunity to develop new insights that advance fundamental aspects of the hydrological sciences. To accomplish this will require more than just an application of the technology: in some cases, it will demand a radical rethink on how we utilize and exploit these new observing systems

13C-ETHANE IN THE ATMOSPHERES OF JUPITER AND SATURN

High-resolution12C- and13C-ethane spectra of Jupiter and Saturn were acquired with the McMath-Pierce 60 inch (1.5 m) Telescope and Celeste, Goddard Space Flight Center's cryogenic grating spectrometer, in 1995 November and December. A relative abundance ratio12C/13C of 91 +26–13 for Jupiter and 99+43-23 for Saturn was derived from the measurements. These nearly terrestrial values suggest little or no fractionation of carbon isotopes in the atmospheres of Jupiter and Saturn. A weighted average of the available12C/13C ratios for the outer planets yields 88 ± 7, thus presenting no evidence for change in the carbon isotopic ratio between the presolar nebula and the present atmospheres of the outer planets

No Fossil Disk in the T Tauri Multiple System V773 Tau

We present new multi-epoch near-infrared and optical high-angular images of the V773 Tau pre-main sequence triple system, a weak-line T Tauri (WTTS) system in which the presence of an evolved, ``fossil'' protoplanetary disk has been inferred on the basis of a significant infrared excess. Our images reveal a fourth object bound to the system, V773 Tau D. While it is much fainter than all other components at 2 micron, it is the brightest source in the system at 4.7 micron. We also present medium-resolution K band adaptive optics spectroscopy of this object, which is featureless with the exception of a weak Br gamma emission line. Based on this spectrum and on the spectral energy distribution of the system, we show that V773 Tau D is another member of the small class of ``infrared companions'' (IRCs) to T Tauri stars. It is the least luminous, and probably the least massive, component of the system, as opposed to most other IRCs, which suggests that numerous low-luminosity IRCs such as V773 Tau D may still remain to be discovered. Furthermore, it is the source of the strong IR excess in the system. We therefore reject the interpretation of this excess as the signature of a fossil (or ``passive'') disk and further suggest that these systems may be much less frequent than previously thought. We further show that V773 Tau C is a variable classical T Tauri star (CTTS) and that its motion provides a well constrained orbital model. We show that V773 Tau D can be dynamically stable within this quadruple system if its orbit is highly inclined. Finally, V773 Tau is the first multiple system to display such a variety of evolutionary states (WTTS, CTTS, IRC), which may be the consequence of the strong star-star interactions in this compact quadruple system.Comment: Accepted for publication in Astrophysical Journal, 29 pages, 2 tables, 5 figure

The Mass Distributions of Starless and Protostellar Cores in Gould Belt Clouds

Using data from the SCUBA Legacy Catalogue (850 um) and Spitzer Space Telescope (3.6 - 70 um), we explore dense cores in the Ophiuchus, Taurus, Perseus, Serpens, and Orion molecular clouds. We develop a new method to discriminate submillimeter cores found by SCUBA as starless or protostellar, using point source photometry from Spitzer wide field surveys. First, we identify infrared sources with red colors associated with embedded young stellar objects (YSOs). Second, we compare the positions of these YSO-candidates to our submillimeter cores. With these identifications, we construct new, self-consistent starless and protostellar core mass functions (CMFs) for the five clouds. We find best fit slopes to the high-mass end of the CMFs of -1.26 +/- 0.20, -1.22 +/- 0.06, -0.95 +/- 0.20, and -1.67 +/- 0.72 for Ophiuchus, Taurus, Perseus, and Orion, respectively. Broadly, these slopes are each consistent with the -1.35 power-law slope of the Salpeter IMF at higher masses, but suggest some differences. We examine a variety of trends between these CMF shapes and their parent cloud properties, potentially finding a correlation between the high-mass slope and core temperature. We also find a trend between core mass and effective size, but we are very limited by sensitivity. We make similar comparisons between core mass and size with visual extinction (for A_V >= 3) and find no obvious trends. We also predict the numbers and mass distributions of cores that future surveys with SCUBA-2 may detect in each of these clouds.Comment: 56 pages, 18 figures, fixed typo in Eq 1, results in paper remain unchange

Biomass burning and urban air pollution over the Central Mexican Plateau

Observations during the 2006 dry season of highly elevated concentrations of cyanides in the atmosphere above Mexico City (MC) and the surrounding plains demonstrate that biomass burning (BB) significantly impacted air quality in the region. We find that during the period of our measurements, fires contribute more than half of the organic aerosol mass and submicron aerosol scattering, and one third of the enhancement in benzene, reactive nitrogen, and carbon monoxide in the outflow from the plateau. The combination of biomass burning and anthropogenic emissions will affect ozone chemistry in the MC outflow