Electrowetting controlled non-volatile integrated optical switch

We present the proof of concept of the first non-volatile bistable fiber optic switch combining integrated optics and electrowetting-actuated microfluidics. Design and realization of both EWOD and photonic layer are presented and successful switching of a 2×4 network is demonstrated

The clinical relevance of oliguria in the critically ill patient : Analysis of a large observational database

Funding Information: Marc Leone reports receiving consulting fees from Amomed and Aguettant; lecture fees from MSD, Pfizer, Octapharma, 3 M, Aspen, Orion; travel support from LFB; and grant support from PHRC IR and his institution. JLV is the Editor-in-Chief of Critical Care. The other authors declare that they have no relevant financial interests. Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients. Using a large multinational database, we therefore evaluated the occurrence of oliguria (defined as a urine output 16 years) patients in the ICON audit who had a urine output measurement on the day of admission were included. To investigate the association between oliguria and mortality, we used a multilevel analysis. Results: Of the 8292 patients included, 2050 (24.7%) were oliguric during the first 24 h of admission. Patients with oliguria on admission who had at least one additional 24-h urine output recorded during their ICU stay (n = 1349) were divided into three groups: transient - oliguria resolved within 48 h after the admission day (n = 390 [28.9%]), prolonged - oliguria resolved > 48 h after the admission day (n = 141 [10.5%]), and permanent - oliguria persisting for the whole ICU stay or again present at the end of the ICU stay (n = 818 [60.6%]). ICU and hospital mortality rates were higher in patients with oliguria than in those without, except for patients with transient oliguria who had significantly lower mortality rates than non-oliguric patients. In multilevel analysis, the need for RRT was associated with a significantly higher risk of death (OR = 1.51 [95% CI 1.19-1.91], p = 0.001), but the presence of oliguria on admission was not (OR = 1.14 [95% CI 0.97-1.34], p = 0.103). Conclusions: Oliguria is common in ICU patients and may have a relatively benign nature if only transient. The duration of oliguria and need for RRT are associated with worse outcome.publishersversionPeer reviewe

Non-volatile microfluidics controlled switch fabricated in fused silica by femtosecond laser inscription

The spreading of fiber to the home technology, driven by the increasing amount of internet traffic over the past decade, requires development of optical power switches (OPSs) for efficient optical network management. Microfluidic Silicon photonics OPSs have recently been proposed as a new class of non-volatile, easily (remotely) reconfigurable switches that could increase the flexibility of a network and help reduce the maintenance costs. As the switching state is controlled by microfluidics, the OPS needs to be powered only at the moment when it needs to be reconfigured

Development of a Model to Estimate the Risk of Emission of Greenhouse Gases from Forest Fires

While the Mediterranean basin is foreseen to be highly affected by climate change (CC) and severe forest fires are expected to be more frequent, international efforts to fight against CC do not consider forest fires’ greenhouse gas (GHG) emissions risk and the possibility of its mitigation. This is partly due to a lack of a methodology for GHG risk spatial assessment and consideration of the high value of carbon stocks in forest ecosystems and their intrinsic risk. To revert this, an innovative GHG emission risk model has been developed and implemented in a pilot forest area. This model considers geospatial variables to build up emission vulnerability based on potential fire severity and resistance of a landscape, value at risk and the hazard of a fire occurrence. The results classify low, moderate and high emission risks in the analysed areas. This identification of hotspots allows the prioritisation of fire prevention measures in a region to maximise the reduction of GHG emissions in the case of a fire event. This constitutes the first step in a holistic and consistent CC mitigation that not only considers anthropic GHG sources but also possible GHG emissions by forest fires that can be actively prevented, managed and reduced