255 research outputs found

    Some properties of the k-dimensional Lyness' map

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    This paper is devoted to study some properties of the k-dimensional Lyness' map. Our main result presentes a rational vector field that gives a Lie symmetry for F. This vector field is used, for k less or equal to 5 to give information about the nature of the invariant sets under F. When k is odd, we also present a new (as far as we know) first integral for F^2 which allows to deduce in a very simple way several properties of the dynamical system generated by F. In particular for this case we prove that, except on a given codimension one algebraic set, none of the positive initial conditions can be a periodic point of odd period.Comment: 22 pages; 3 figure

    Tailoring the flow of soft glasses by soft additives

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    We examine the vitrification and melting of asymmetric star polymers mixtures by combining rheological measurements with mode coupling theory. We identify two types of glassy states, a {\it single} glass, in which the small component is fluid in the glassy matrix of the big one and a {\it double} glass, in which both components are vitrified. Addition of small star polymers leads to melting of {\it both} glasses and the melting curve has a non-monotonic dependence on the star-star size ratio. The phenomenon opens new ways for externally steering the rheological behavior of soft matter systems.Comment: 4 pages, 4 figures, accepted in Phys. Rev. Let

    Construction of Integrals of Higher-Order Mappings

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    We find that certain higher-order mappings arise as reductions of the integrable discrete A-type KP (AKP) and B-type KP (BKP) equations. We find conservation laws for the AKP and BKP equations, then we use these conservation laws to derive integrals of the associated reduced maps.Comment: appear to Journal of the Physical Society of Japa

    Palaeoenvironmental implications of a marine geoarchaeological survey conducted in the SW Argosaronic gulf, Greece

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    AbstractA marine geoarcheological survey was conducted at the southwestern end of the Argosaronic gulf in Greece, an area of archaeological importance. The survey was initiated by the discovery of a Late Bronze Age (LBA) shipwreck off Modi Islet. The survey which employed echo-sounding, sub-bottom profiling, side scan sonar systems and sediment coring extended to the area between Poros Island, Modi Islet and Argolid peninsula, aiming to evaluate the changes of the coastal zone extent in the past. The evolution of the palaeo-shoreline over the last 20ka is proposed based on the interpretation of the acquired bathymetric and seismic records, the estimation of the thickness of the marine sediments and the examination of existing datasets of the relative sea level changes in the area.The produced scenarios suggest that major changes marked the extent of the coastal zone since the Paleolithics. During the Upper Paleolithic period, the coast was larger by at least 11km2 and Poros and Modi islands were connected to the Peloponnesus. The sea level rise during the Mesolithic period formed a well-protected bay between Poros Island and Peloponessus and disconnected the Modi Islet from Poros Island. The coastal zone reached the present configuration around Late Bronze Age. The detection and mapping of scarps on the seismic profiles imply that the sea level rise presented standstills at least from the Last Glacial maximum until the onset of Holocene. However, the submerged coasts could be potential areas of archaeological interest since the examined area is habited continuously from the Paleolithic period.The acoustic data sets produced high resolution geomorphological maps at the wreck site which constitute data base for the monitoring of the site. In addition, the examination of the seafloor texture at the wreck site suggests that the seafloor characteristics were unfavorable for the preservation of the shipwreck

    Exploring the interactions of irbesartan and irbesartan–2-hydroxypropyl-β-cyclodextrin complex with model membranes

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    The interactions of irbesartan (IRB) and irbesartan–2-hydroxypropyl-β-cyclodextrin (HP-β-CD) complex with Dipalmitoyl Phosphatidylcholine (DPPC) bilayers have been explored utilizing an array of biophysical techniques ranging from Differential Scanning Calorimetry (DSC), Small angle X-ray Scattering (SAXS), ESI Mass-Spectrometry (ESI-MS) and solid state Nuclear Magnetic Resonance (ssNMR). Molecular Dynamics (MD) calculations have been also conducted to complement the experimental results. Irbesartan was found to be embedded in the lipid membrane core and to affect the phase transition properties of the DPPC bilayers. SAXS studies revealed that irbesartan alone does not display perfect solvation since some coexisting irbesartan crystallites are present. In its complexed form IRB gets fully solvated in the membranes showing that encapsulation of IRB in HP-β-CD may have beneficial effects in the ADME properties of this drug. MD experiments revealed the topological and orientational integration of irbesartan into the phospholipid bilayer being placed at about 1 nm from the membrane centre

    Orbital Angular Momentum (OAM) of Rotating Modes Driven by Electrons in Electron Cyclotron Masers

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    The well-defined orbital angular momentum (OAM) of rotating cavity modes operating near the cutoff frequency excited by gyrating electrons in a high-power electron cyclotron maser (ECM)-a gyrotron-has been derived by photonic and electromagnetic wave approaches. A mode generator was built with a high-precision 3D printing technique to mimic the rotating gyrotron modes for precise low-power measurements and shows clear natural production of higher-order OAM modes. Cold-test measurements of higher-order OAM mode generation promise the realization towards wireless long-range communications using high-power ECMs

    Expression and Membrane Topology of Anopheles gambiae Odorant Receptors in Lepidopteran Insect Cells

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    A lepidopteran insect cell-based expression system has been employed to express three Anopheles gambiae odorant receptors (ORs), OR1 and OR2, which respond to components of human sweat, and OR7, the ortholog of Drosophila's OR83b, the heteromerization partner of all functional ORs in that system. With the aid of epitope tagging and specific antibodies, efficient expression of all ORs was demonstrated and intrinsic properties of the proteins were revealed. Moreover, analysis of the orientation of OR1 and OR2 on the cellular plasma membrane through the use of a novel ‘topology screen’ assay and FACS analysis demonstrates that, as was recently reported for the ORs in Drosophila melanogaster, mosquito ORs also have a topology different than their mammalian counterparts with their N-terminal ends located in the cytoplasm and their C-terminal ends facing outside the cell. These results set the stage for the production of mosquito ORs in quantities that should permit their detailed biochemical and structural characterization and the exploration of their functional properties

    Molecular and Functional Characterization of the Odorant Receptor2 (OR2) in the Tiger Mosquito Aedes albopictus

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    In mosquitoes, the olfactory system plays a crucial role in many types of behavior, including nectar feeding, host preference selection and oviposition. Aedes albopictus, known also as the tiger mosquito, is an anthropophilic species, which in the last few years, due to its strong ecological plasticity, has spread throughout the world. Although long considered only a secondary vector of viruses, the potential of its vector capacity may constitute a threat to public health. Based on the idea that an improved understanding of the olfactory system of mosquitoes may assist in the development of control methods that interfere with their behavior, we have undertaken a study aimed at characterizing the A. albopictus Odorant Receptors. Here we report the identification, cloning and functional characterization of the AalOR2 ortholog, that represents the first candidate member of the odorant receptor (OR) family of proteins from A. albopictus. AalOR2 is expressed in the larval heads and antennae of adults. Our data indicate that A. albopictus OR2 (AalOR2) shares a high degree of identity with other mosquito OR2 orthologs characterized to date, confirming that OR2 is one of the most conserved mosquito ORs. Our data indicate that AalOR2 is narrowly tuned to indole, and inhibited by (-)-menthone. In agreement with this results, these two compounds elicit two opposite effects on the olfactory-based behavior of A. albopictus larvae, as determined through a larval behavioral assay. In summary, this work has led to the cloning and de-orphaning of the first Odorant Receptor in the tiger mosquito A. albopictus. In future control strategies this receptor may be used as a potential molecular target

    Platelet-activating factor levels of serum and gingival crevicular fluid in nonsmoking patients with periodontitis and/or coronary heart disease

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    The purpose of the present study was to investigate systemic and local levels of platelet-activating factor (PAF), a potent proinflammatory mediator implicated in cardiovascular pathophysiology in adult nonsmoking patients with periodontitis with or without coronary heart disease (CHD). Eighty-seven volunteers, 25 periodontitis patients, 19 periodontitis with CHD patients, 19 CHD patients, and 24 healthy controls were included, and periodontal conditions were assessed. Gingival crevicular fluid (GCF) and venous blood were collected, and PAF levels were measured by enzyme-linked immunosorbent assay. PAF levels in serum (303.3 ± 204 pg/ml) and in GCF (26.3 ± 6 pg/μl) of the periodontitis group with CHD, the periodontitis group (serum, 302.4 ± 241 pg/ml and GCF, 26.3 ± 8 pg/μl) and the CHD group (serum, 284.7 ± 192 pg/ml and GCF, 20.8 ± 6 pg/μl) were significantly higher than the healthy control group (serum, 65.4 ± 35 pg/ml and GCF, 7.7 ± 3 pg/μl; p < 0.05). In summary, the present study could demonstrate that in patients with periodontitis, the inflammatory mediator PAF is released into serum at least in the same range as for patients with coronary heart disease. However, no additive effects were seen when both conditions were present
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