547 research outputs found
Tocar el tango hoy: estilo compositivo y estilo de ejecución
El estilo del tango se ha desarrollado al calor de sus prácticas de ejecución. Para investigarlo se necesita incorporar al análisis de la composición escrita, el estudio de sus rasgos performativos, postulando una interdependencia entre estilo compositivo y estilo de ejecución. Así, movimiento, sonido, texto musical y práctica en contexto forman el corpus del presente trabajo.Área: Ciencias Sociales y Humana
Functional evolution of quantum cylindrical waves
Kucha{\v{r}} showed that the quantum dynamics of (1 polarization) cylindrical
wave solutions to vacuum general relativity is determined by that of a free
axially-symmetric scalar field along arbitrary axially-symmetric foliations of
a fixed flat 2+1 dimensional spacetime. We investigate if such a dynamics can
be defined {\em unitarily} within the standard Fock space quantization of the
scalar field.
Evolution between two arbitrary slices of an arbitrary foliation of the flat
spacetime can be built out of a restricted class of evolutions (and their
inverses). The restricted evolution is from an initial flat slice to an
arbitrary (in general, curved) slice of the flat spacetime and can be
decomposed into (i) `time' evolution in which the spatial Minkowskian
coordinates serve as spatial coordinates on the initial and the final slice,
followed by (ii) the action of a spatial diffeomorphism of the final slice on
the data obtained from (i). We show that although the functional evolution of
(i) is unitarily implemented in the quantum theory, generic spatial
diffeomorphisms of (ii) are not. Our results imply that a Tomanaga-Schwinger
type functional evolution of quantum cylindrical waves is not a viable concept
even though, remarkably, the more limited notion of functional evolution in
Kucha{\v{r}}'s `half parametrized formalism' is well-defined.Comment: Replaced with published versio
Electron gas polarization effect induced by heavy H-like ions of moderate velocities channeled in a silicon crystal
We report on the observation of a strong perturbation of the electron gas
induced by 20 MeV/u U ions and 13 MeV/u Pb ions channeled in
silicon crystals. This collective response (wake effect) in-duces a shift of
the continuum energy level by more than 100 eV, which is observed by means of
Radiative Electron Capture into the K and L-shells of the projectiles. We also
observe an increase of the REC probability by 20-50% relative to the
probability in a non-perturbed electron gas. The energy shift is in agreement
with calculations using the linear response theory, whereas the local electron
density enhancement is much smaller than predicted by the same model. This
shows that, for the small values of the adiabaticity parameter achieved in our
experiments, the density fluctuations are not strongly localized at the
vicinity of the heavy ions
Minimizing energy below the glass thresholds
Focusing on the optimization version of the random K-satisfiability problem,
the MAX-K-SAT problem, we study the performance of the finite energy version of
the Survey Propagation (SP) algorithm. We show that a simple (linear time)
backtrack decimation strategy is sufficient to reach configurations well below
the lower bound for the dynamic threshold energy and very close to the analytic
prediction for the optimal ground states. A comparative numerical study on one
of the most efficient local search procedures is also given.Comment: 12 pages, submitted to Phys. Rev. E, accepted for publicatio
Who’s in Charge Now? The Decision Autonomy of Hotel General Managers
The general manager (GM) is the key position in a hotel, but the changing structure of the industry has altered the scope of the GM’s decision-making autonomy. In many hotels, the GM is an employee of a hotel operating firm and is effectively an agent of the operator or owner (and sometimes both parties). These principals have authority over several aspects of hotel operation, although the GM also has responsibility. A study of the GM’s role and authority in 115 upscale European hotels finds a mixed picture in decision autonomy, depending on the individual’s experience and education, as well as whether the hotel is independent or chain managed. Overall, independent GMs have greater autonomy in their properties than chain GMs, and highly experienced managers are often given greater autonomy by independent owners, while operating companies give greater autonomy to GMs who offer a combination of education and experience. With regard to individual functional areas, chain GMs have relatively greater authority in human resources, marketing, and strategy but limited autonomy in finance and operations
Interobserver agreement in dysplasia grading: toward an enhanced gold standard for clinical pathology trials
Objective: Interobserver agreement in the context of oral epithelial dysplasia (OED) grading has been notoriously unreliable and can impose barriers for developing new molecular markers and diagnostic technologies. This paper aimed to report the details of a 3-stage histopathology review and adjudication process with the goal of achieving a consensus histopathologic diagnosis of each biopsy. Study Design: Two adjacent serial histologic sections of oral lesions from 846 patients were independently scored by 2 different pathologists from a pool of 4. In instances where the original 2 pathologists disagreed, a third, independent adjudicating pathologist conducted a review of both sections. If a majority agreement was not achieved, the third stage involved a face-to-face consensus review. Results: Individual pathologist pair κ values ranged from 0.251 to 0.706 (fair-good) before the 3-stage review process. During the initial review phase, the 2 pathologists agreed on a diagnosis for 69.9% of the cases. After the adjudication review by a third pathologist, an additional 22.8% of cases were given a consensus diagnosis (agreement of 2 out of 3 pathologists). After the face-to-face review, the remaining 7.3% of cases had a consensus diagnosis. Conclusions: The use of the defined protocol resulted in a substantial increase (30%) in diagnostic agreement and has the potential to improve the level of agreement for establishing gold standards for studies based on histopathologic diagnosis
Healthcare designers’ use of prescriptive and performance-based approaches
In the UK, healthcare built environment design is guided by a series of long-established design standards and guidance issued by the Department of Health. More recently, healthcare design focus has broadened to encompass new approaches, supported by large bodies of credible research evidence. It is therefore timely to rethink how healthcare design standards and guidance should be best expressed to suit ‘designerly ways’ of using evidence, to improve their use and effectiveness in practice. This research explored how designers use performance and prescriptive approaches during the healthcare design process. Three in-depth healthcare built environment case studies were used to explore how designers employed such approaches during the design of selected exemplar design elements. Results show that design elements in the pre and conceptual design phases significantly employed performance-based approaches, and due to project-unique circumstances, prescriptive solutions were often significantly modified based on performance criteria. For design elements in the detailed and technical design phases, there was a significant use of solutions based on prescriptive approaches, whilst performance-based criteria were used to evaluate design solutions. This research proposes a performance-based, specification-driven healthcare design with supplementary prescriptive specifications provided for optimum healthcare environment design
‘Cytology-on-a-chip’ based sensors for monitoring of potentially malignant oral lesions
Despite significant advances in surgical procedures and treatment, long-term prognosis for patients with oral cancer remains poor, with survival rates among the lowest of major cancers. Better methods are desperately needed to identify potential malignancies early when treatments are more effective. Objective To develop robust classification models from cytology-on-a-chip measurements that mirror diagnostic performance of gold standard approach involving tissue biopsy. Materials and methods Measurements were recorded from 714 prospectively recruited patients with suspicious lesions across 6 diagnostic categories (each confirmed by tissue biopsy -histopathology) using a powerful new ‘cytology-on-a-chip’ approach capable of executing high content analysis at a single cell level. Over 200 cellular features related to biomarker expression, nuclear parameters and cellular morphology were recorded per cell. By cataloging an average of 2000 cells per patient, these efforts resulted in nearly 13 million indexed objects. Results Binary “low-risk”/“high-risk” models yielded AUC values of 0.88 and 0.84 for training and validation models, respectively, with an accompanying difference in sensitivity + specificity of 6.2%. In terms of accuracy, this model accurately predicted the correct diagnosis approximately 70% of the time, compared to the 69% initial agreement rate of the pool of expert pathologists. Key parameters identified in these models included cell circularity, Ki67 and EGFR expression, nuclear-cytoplasmic ratio, nuclear area, and cell area. Conclusions This chip-based approach yields objective data that can be leveraged for diagnosis and management of patients with PMOL as well as uncovering new molecular-level insights behind cytological differences across the OED spectrum
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