Business Process Retrieval Based on Behavioral Semantics

This paper develops a framework for retrieving business processes considering search requirements based on behavioral semantics properties; it presents a framework called "BeMantics" for retrieving business processes based on structural, linguistics, and behavioral semantics properties. The relevance of the framework is evaluated retrieving business processes from a repository, and collecting a set of relevant business processes manually issued by human judges. The "BeMantics" framework scored high precision values (0.717) but low recall values (0.558), which implies that even when the framework avoided false negatives, it prone to false positives. The highest pre- cision value was scored in the linguistic criterion showing that using semantic inference in the tasks comparison allowed to reduce around 23.6 % the number of false positives. Using semantic inference to compare tasks of business processes can improve the precision; but if the ontologies are from narrow and specific domains, they limit the semantic expressiveness obtained with ontologies from more general domains. Regarding the perform- ance, it can be improved by using a filter phase which indexes business processes taking into account behavioral semantics propertie

Business Process Retrieval Based on Behavioral Semantics

This paper develops a framework for retrieving business processes considering search requirements based on behavioral semantics properties; it presents a framework called “BeMantics” for retrieving business processes based on structural, linguistics, and behavioral semantics properties. The relevance of the framework is evaluated retrieving business processes from a repository, and collecting a set of relevant business processes manually issued by human judges. The “BeMantics” framework scored high precision values (0.717) but low recall values (0.558), which implies that even when the framework avoided false negatives, it prone to false positives. The highest pre- cision value was scored in the linguistic criterion showing that using semantic inference in the tasks comparison allowed to reduce around 23.6 % the number of false positives. Using semantic inference to compare tasks of business processes can improve the precision; but if the ontologies are from narrow and specific domains, they limit the semantic expressiveness obtained with ontologies from more general domains. Regarding the perform- ance, it can be improved by using a filter phase which indexes business processes taking into account behavioral semantics properties

Significados del conocimiento geométrico que circula en el nivel medio y en la formación inicial del profesor en matemáticas: un problema de investigación

Esta investigación científica, hace foco en la necesaria articulación de la formación del profesor con su gestión en el nivel en el que desarrolla su actividad profesional. Para ello trata de estudiar y analizar el funcionamiento de la enseñanza del saber geométrico en su conjunto. La investigación está centrada en la exploración de significados institucionales y personales correspondiente al campo de la geometría que “vive” en la escuela media y en la formación inicial del profesor en matemática correspondiente a la zona del Golfo San Jorge de Argentina (Provincias de Chubut y Santa Cruz). Se pretende arribar a algunos criterios idóneos para analizar y rever los planes de estudio para la formación de docentes de nivel medio, fundando algunas recomendaciones de tareas/situaciones/cuestiones, técnicas y tecnologías del desarrollo teórico de la Geometría que debieran estar presentes en dicha formación, desarrollar un conjunto de prácticas geométricas para la formación inicial de los profesores en matemática

Contribuições do núcleo interinstitucional de agroecologia de Jaguariúna/SP em processos participativos de desenvolvimento rural sustentável.

Resumo: Neste relato apresentamos a experiência da construção de conhecimento agroecológico, desenvolvida na Embrapa Meio Ambiente, Jaguariúna-SP, realizada a partir de 2008. O trabalho contempla a criação e o desenvolvimento de um Núcleo de Agroecologia, interinstitucional e transdiciplinar, composto por pesquisadores, técnicos e agricultores. O objetivo do núcleo é promover, de forma participativa, ações para a evolução do processo de transição agroecológica regional e a construção do conhecimento agroecológico, a partir da identificação das questões limitantes do processo e da integração entre agentes de desenvolvimento regional e agricultores. Os membros do núcleo interinstitucional gerenciam uma área demonstrativa, denominada Sítio Agroecológico, utilizada para demonstrar concretamente conceitos e conhecimentos dos processos ecológicos nos sistemas produtivos, pela implantação, manutenção e monitoramento de unidades de observação. O Sítio configura-se como um elemento integrador do núcleo inteinstitucional, já que ao promover a troca de experiências entre os membros a partir do exercício prático e presencial de atividades em campo

Nitric oxide inactivates rat hepatic methionine adenosyltransferase In vivo by S-nitrosylation

We investigated the mechanism of nitric oxide (NO) action on hepatic methionine adenosyltransferase (MAT) activity using S-nitrosoglutathione (GSNO) as NO donor. Hepatic MAT plays an essential role in the metabolism of methionine, converting this amino acid into S-adenosylmethionine. Hepatic MAT exists in two oligomeric states: as a tetramer (MAT I) and as a dimer (MAT III) of the same subunit. This subunit contains 10 cysteine residues. In MAT I, S-nitrosylation of 1 thiol residue per subunit was associated with a marked inactivation of the enzyme (about 70%) that was reversed by glutathione (GSH). In MAT III, S-nitrosylation of 3 thiol residues per subunit led to a similar inactivation of the enzyme, which was also reversed by GSH. Incubation of isolated rat hepatocytes with S-nitrosoglutathione monoethyl ester (EGSNO), a NO donor permeable through the cellular membrane, induced a dose-dependent inactivation of MAT that was reversed by removing the NO donor from the cell suspension. MAT, purified from isolated rat hepatocytes, contained S-nitrosothiol groups and the addition of increasing concentrations of EGSNO to the hepatocyte suspension led to a progressive S-nitrosylation of the enzyme. Removal of the NO donor from the incubation media resulted in loss of most NO groups associated to the enzyme. Finally, induction in rats of the production of NO, by the administration of bacterial lipopolysaccharide (LPS), induced a fivefold increase in the S-nitrosylation of hepatic MAT, which led to a marked inactivation of the enzyme. Thus, the activity of liver MAT appears to be regulated in vivo by S-nitrosylation

Microscopic theory of network glasses

A molecular theory of the glass transition of network forming liquids is developed using a combination of self-consistent phonon and liquid state approaches. Both the dynamical transition and the entropy crisis characteristic of random first order transitions are mapped out as a function of the degree of bonding and the density. Using a scaling relation for a soft-core model to crudely translate the densities into temperatures, the theory predicts that the ratio of the dynamical transition temperature to the laboratory transition temperature rises as the degree of bonding increases, while the Kauzmann temperature falls relative to the laboratory transition. These results indicate why highly coordinated liquids should be "strong" while van der Waals liquids without coordination are "fragile".Comment: slightly revised version that has been accepted for publication in Phys. Rev. Let

Uso didáctico de los recursos tecnólogicos en la labor docente en Centros Escolares de Educación Primaria

Este estudio planteó como problema, el aprovechamiento que le dan los maestros al uso de los recursos tecnológicos en su labor docente, gracias a las capacitaciones ofrecidas por el Ministerio de Educación panameño, en los seminarios ENTRE PARES N° 1 y 2, en los cuales muchos maestros desarrollaron competencias digitales; mientras otros olvidaron los conocimientos adquiridos por no usarlos con frecuencia. El objetivo general del estudio es evaluar la relación entre el uso didáctico de los recursos tecnológicos y el mejoramiento de la labor docente en las instituciones escolares del nivel primario. De allí se desdoblaron los objetivos específicos consistentes en establecer el perfil característico de los docentes de grado y especiales, determinando y analizando el uso didáctico que los maestros le daban a los recursos tecnológicos para mejorar su labor docente. Para este efecto se trabajó directamente con la población total de tres (3) centros educativos, la cual hace un total de 145 maestros y 3 directores, utilizando un cuestionario con preguntas abiertas y cerradas, de 53 ítems para los maestros y de 32, para los directores. El tipo de estudio fue descriptivo, sometido al análisis de las variables en donde se utilizaron porcentajes, tablas de distribución de frecuencias y gráficas usando el programa estadístico SPSS22. Los hallazgos señalaron que de hecho ha mejorado la labor docente y el proceso didáctico, gracias al uso de los recursos tecnológicos; sin embargo, aún carecen de una comisión para el seguimiento, monitoreo y evaluación, tan necesarios en los procesos de mejoramiento de calidad e innovación de los centros educativos

Design of a large scale flow-meter test and calibration facility

The design and set up of a large-scale flowmeter calibration and test facility is presented. The facility was designed to handle flowmeters with diameters between 6” and 14”, flow rates up to 0.3 m3/s and to give results less than 1% accurate. The calibration methodology consisted firstly in calibrating the pattern flowmeters, using volume and time primary measurements, and secondly, comparing the pattern to the flowmeters needing calibration. The design and calculation of the primary calibration device is addressed, including numerical simulations of the outflow manifold and the comparison to experimental data. The calibration facility proved to be accurate and reliable in producing renewed calibration data for various tested flowmeter

Análisis proteómico de células de Hepatoma Huh7 transfectadas con MAT1A.Caracterización de DDX3X como diana de la S-adenosilmetionina

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