420 research outputs found

    A fast and low noise charge sensitive preamplifier in 90 nm CMOS technology

    Get PDF
    A fast charge sensitive preamplifier was designed and built in a 90 nm CMOS technology. The work is part of the R&D effort towards the read out of pixel or small strip sensors in next generation HEP experiments. The preamplifier features outstanding noise performance given its wide bandwidth, with a ENC (equivalent noise charge) of about 350 electrons RMS with a detector of 1 pF capacitance. With proper filtering, the ENC drops to less than 200 electrons RMS. Power consumption is 5 mW for one channel, and the closed loop bandwith is about 180 MHz, for a risetime down to 2 ns in the fastest operation mode. Thanks to some freedom left to the user in setting the open loop gain, detectors with larger source capacitance can be read out without significant loss in bandwidth, being the rise time still 5.5 ns for a 5.6 pF detector. The output can drive a 50 Ω terminated transmission line. © 2012 2012 IOP Publishing Ltd and SISSA

    Cryptogenic Epileptic Syndromes Related to SCN1A Twelve Novel Mutations Identified

    Get PDF
    Background: Sodium channel alpha 1 subunit gene, SCN1A, is the gene encoding the neuronal voltage-gated sodium channel alpha 1 subunit (Na(v)1.1) and is mutated in different forms of epilepsy. Mutations in this gene were observed in more than 70% of patients with severe myoclonic epilepsy of infancy (SMEI) and were also found in different types of infantile epileptic encephalopathy. Objective: To search for disease-causing mutations in SCN1A in patients with cryptogenic epileptic syndromes (ie, syndromes with an unknown cause). Design: Clinical characterization and molecular genetic analysis of a cohort of patients. Setting: University hospitals, rehabilitation centers, and molecular biology laboratories. Patients: Sixty unrelated patients with cryptogenic epileptic syndromes. Main Outcome Measures: Samples of DNA were analyzed for mutations and for large heterozygous deletions encompassing the SCN1A gene. A search for microdeletions in the SCN1A gene was also performed in the subset of patients with SMEI/SMEI-borderland who had negative results at the point mutation screening. Results: No large deletions at the SCN1A locus were found in any of the patients analyzed. In contrast, 13 different point mutations were identified in 12 patients: 10 with SMEI, 1 with generalized epilepsy with febrile seizures plus, and 1 with cryptogenic focal epilepsy. An additional search for SCN1A intragenic microdeletions in the remaining patients with SMEI/SMEI-borderland and no point mutations was also negative. Conclusions: These results confirm the role of the SCN1A gene in different types of epilepsy, including cryptogenic epileptic syndromes. However, large deletions encompassing SCN1A were not common disease-causing rearrangements in this group of epilepsies

    A coherent polarimeter array for the Large Scale Polarization Explorer balloon experiment

    Full text link
    We discuss the design and expected performance of STRIP (STRatospheric Italian Polarimeter), an array of coherent receivers designed to fly on board the LSPE (Large Scale Polarization Explorer) balloon experiment. The STRIP focal plane array comprises 49 elements in Q band and 7 elements in W-band using cryogenic HEMT low noise amplifiers and high performance waveguide components. In operation, the array will be cooled to 20 K and placed in the focal plane of a 0.6\sim 0.6 meter telescope providing an angular resolution of 1.5\sim1.5 degrees. The LSPE experiment aims at large scale, high sensitivity measurements of CMB polarization, with multi-frequency deep measurements to optimize component separation. The STRIP Q-band channel is crucial to accurately measure and remove the synchrotron polarized component, while the W-band channel, together with a bolometric channel at the same frequency, provides a crucial cross-check for systematic effects.Comment: In press on the Proceedings of the SPIE Conference Astronomical Telescopes + instrumentation 2012, Amsterdam, paper 8446-27

    Внедрение и принцип работы системы сейсмического мониторинга горного массива для работы в условиях ООО "Шахта "Усковская"

    Get PDF
    The status of the Silicon Microvertex Detector (SMD) and its installation into the LEP-L3 experiment are presented, highlighting novel features and sophisticated techniques. Preliminary results based on 1993 data are given and compared with Monte Carlo predictions, to understand the detector performances and its tracking capabilities

    Search for neutral charmless B decays at LEP

    Get PDF
    A search for rare charmless decays of \Bd and \Bs mesons has been performed in the exclusive channels \Bd_{(\mathrm s)}\ra\eta\eta, \Bd_{(\mathrm s)}\ra\eta\pio and \Bd_{(\mathrm s)}\ra\pio\pio. The data sample consisted of three million hadronic \Zo decays collected by the L3 experiment at LEP from 1991 through 1994. No candidate event has been observed and the following upper limits at 90\% confidence level on the branching ratios have been set \begin{displaymath} \mathrm{Br}(\Bd\ra\eta\eta)<4.1\times 10^{-4},\,\, \mathrm{Br}(\Bs\ra\eta\eta)<1.5\times 10^{-3},\,\, \end{displaymath} \begin{displaymath} \mathrm{Br}(\Bd\ra\eta\pio)<2.5\times 10^{-4},\,\, \mathrm{Br}(\Bs\ra\eta\pio)<1.0\times 10^{-3},\,\, \end{displaymath} \begin{displaymath} \mathrm{Br}(\Bd\ra\pio\pio)<6.0\times 10^{-5},\,\, \mathrm{Br}(\Bs\ra\pio\pio)<2.1\times 10^{-4}. \end{displaymath} These are the first experimental limits on \Bd\ra\eta\eta and on the \Bs neutral charmless modes

    Measurement of energetic single-photon production at LEP

    Get PDF

    Measurement of the Average Lifetime of b-Hadrons in Z Decays

    Get PDF
    We present a measurement of the average b-hadron lifetime τb{\rm \tau_b} at the e+e\mathrm{e^+e^-} \, collider LEP. Using hadronic Z decays collected in the period from 1991 to 1994, two independent analyses have been performed. In the first one, the b-decay position is reconstructed as a secondary vertex of hadronic b-decay particles. The second analysis is an updated measurement of τb{\rm \tau_b} using the impact parameter of leptons with high momentum and high transverse momentum. The combined result is \begin{center} τb=[1549±9(stat)±15(syst)]  fs{\rm \tau_b= [ 1549 \pm 9 \, (stat) \, \pm 15 \, (syst) ] \; fs \,} . \end{center} In addition, we measure the average charged b-decay multiplicity nb{\rm \langle n_{\rm b}} \rangle and the normalized average b-energy xEb{\rm \langle x_E \rangle_{\rm b}} at LEP to be \begin{center} nb=4.90±0.04 (stat)±0.11(syst){\rm \langle n_{\rm b} \rangle = 4.90 \pm 0.04 \ (stat) \pm 0.11 \, (syst)} , \end{center} \begin{center} xEb=0.709±0.004(stat+syst).{\rm \langle x_E \rangle_{\rm b} = 0.709 \pm 0.004 \, (stat + syst).} \end{center

    B^{*} production in Z decays at LEP

    Get PDF

    Energy and particle flow in three-jet and radiative two-jet events from hadronic Z decays

    Get PDF

    Measurement of the inclusive charmless semileptonic branching fraction of beauty hadrons and a determination of |VubV_{ub}| at LEP

    Get PDF
    A measurement of the inclusive charmless semileptonic branching fraction of beauty hadrons, bXuν\mathrm{b}\rightarrow\mathrm{X}_\mathrm{u }\ell\nu, has been performed using almost two million hadronic Z decays collected by the L3 experiment at LEP, yielding the result: \begin{displaymath} \mathrm{Br}(\mathrm{b}\rightarrow\mathrm{X}_\mathr m{u}\ell\nu) = (3.3 \pm 1.0 \pm 1.7)\times 10^{-3}. \end{displaymath} The first uncertainty is statistical and the second is systematic. The modulus of the Cabibbo-Kobayashi-Maskawa matrix element Vub\mathrm{V_{ub}} extracted from this measurement is: \begin{displaymath} |\mathrm{V_{ub}}| = (6.0\, ^{+0.8}_{-1.0} \, ^{+1.4}_{-1.9} \pm 0.2)\times 10^{-3}, \end{displaymath} where the uncertainties are statistical, systematic and theoretical, respectively
    corecore