325 research outputs found

    A systematic review and meta-analysis of transdiagnostic cognitive behavioural therapies for emotional disorders

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    Transdiagnostic cognitive behavioural psychotherapy (TD-CBT) may facilitate the treatment of emotional disorders. Here we investigate short- and long-term efficacy of TD-CBT for emotional disorders in individual, group and internet-based settings in randomized controlled trials (PROSPERO CRD42019141512). Two independent reviewers screened results from PubMed, MEDLINE, PsycINFO, Google Scholar, medRxiv and OSF Preprints published between January 2000 and June 2023, selected studies for inclusion, extracted data and evaluated risk of bias (Cochrane risk-of-bias tool 2.0). Absolute efficacy from pre- to posttreatment and relative efficacy between TD-CBT and control treatments were investigated with random-effects models. Of 56 identified studies, 53 (6,705 participants) were included in the meta-analysis. TD-CBT had larger effects on depression (g = 0.74, 95% CI = 0.57–0.92, P < 0.001) and anxiety (g = 0.77, 95% CI = 0.56–0.97, P < 0.001) than did controls. Across treatment formats, TD-CBT was superior to waitlist and treatment-as-usual. TD-CBT showed comparable effects to disorder-specific CBT and was superior to other active treatments for depression but not for anxiety. Different treatment formats showed comparable effects. TD-CBT was superior to controls at 3, 6 and 12 months but not at 24 months follow-up. Studies were heterogeneous in design and methodological quality. This review and meta-analysis strengthens the evidence for TD-CBT as an efficacious treatment for emotional disorders in different settings

    Йосиф Конрадович Пачоський: історіографія проблеми

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    Проаналізовано наукові, науково-популярні, публіцистичні, літературні джерела щодо біографії і наукової діяльності Й.К. Почоського, розділені на три періоди: перший — дореволюційний період вивчення життєвого шляху та наукової діяльності вченого (1882—1917), другий — радянський (1917—1989), третій — сучасний (1989 р.). Окрім вітчизняних, висвітлено праці дослідників із Польщі.Проанализированы научные, научно-популярные, публицистические, литературные источники по биографии и научной деятельности И.К.Пачоского, разделенные на три периода: первый — дореволюционный период изучения жизненного пути и научной деятельности ученого (1882—1917), второй советский (1917—1989), третий — современный (с 1989 г. ). Кроме отечественных, освещены работы исследователей из Польши.The paper contains analysis of scientific, popular-scientific, publicistic and literary sources on the scientific biography of I.K. Pachosky, divided in the three periods: first — pre-revolutionary (1882—1917), second — soviet (1917—1989), third — contemporary (1989 and on). Apart from national scientists, works of scientists from Poland also included

    A systematic review and meta-analysis of transdiagnostic cognitive behavioural therapies for emotional disorders

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    Transdiagnostic cognitive behavioural psychotherapy (TD-CBT) may facilitate the treatment of emotional disorders. Here we investigate short- and long-term efficacy of TD-CBT for emotional disorders in individual, group and internet-based settings in randomized controlled trials (PROSPERO CRD42019141512). Two independent reviewers screened results from PubMed, MEDLINE, PsycINFO, Google Scholar, medRxiv and OSF Preprints published between January 2000 and June 2023, selected studies for inclusion, extracted data and evaluated risk of bias (Cochrane risk-of-bias tool 2.0). Absolute efficacy from pre- to posttreatment and relative efficacy between TD-CBT and control treatments were investigated with random-effects models. Of 56 identified studies, 53 (6,705 participants) were included in the meta-analysis. TD-CBT had larger effects on depression (g = 0.74, 95% CI = 0.57–0.92, P < 0.001) and anxiety (g = 0.77, 95% CI = 0.56–0.97, P < 0.001) than did controls. Across treatment formats, TD-CBT was superior to waitlist and treatment-as-usual. TD-CBT showed comparable effects to disorder-specific CBT and was superior to other active treatments for depression but not for anxiety. Different treatment formats showed comparable effects. TD-CBT was superior to controls at 3, 6 and 12 months but not at 24 months follow-up. Studies were heterogeneous in design and methodological quality. This review and meta-analysis strengthens the evidence for TD-CBT as an efficacious treatment for emotional disorders in different settings

    When neglected species gain global interest: Lessons learned from quinoa's boom and bust for teff and minor millet

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    Until recently, many so-called neglected and underutilized species (NUS) were not present in global markets despite playing a pivotal role in the local livelihoods in their places of origin. Today, some NUS receive substantial global interest and face growing global demands. Sudden increases in consumer demand trigger prices to rise; land-use change at the farm and national levels results in a rapid production increase. This phenomenon is known as “boom” and is usually followed by a “bust”, a rapid decrease in prices, and subsequently, production. This review elaborates on the boom-and-bust phases of two NUS: quinoa from the Andes and teff from Ethiopia. We explored the potential upcoming boom of minor millets in India. Our study proposes a generic framework for exploring cross-scale interactions and rethinking sustainability pathways for future NUS booms.EEA FamailláFil: Andreotti, Federico. Wageningen University & Research. Laboratory of Geo-information Science and Remote Sensing; Países BajosFil: Andreotti, Federico. CIRAD; FranciaFil: Andreotti, Federico. Université Paul Valery Montpellier; FranciaFil: Bazile, Didier. CIRAD; FranciaFil: Bazile, Didier. Université Paul Valery Montpellier; FranciaFil: Biaggi, Maria Cristina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Famaillá; ArgentinaFil: Callo-Concha, Daniel. University of Bonn. Center for Development Research (ZEF); AlemaniaFil: Callo-Concha, Daniel. University of Koblenz-Landau. Institute for Environmental Sciences (iES); AlemaniaFil: Jacquet, Julie. University Paris Ouest-Nanterre (LAVUE); FranciaFil: Jacquet, Julie. French Institute of Pondicherry; IndiaFil: Jemal, Omarsherif M. Arsi University. College of Agriculture and Veterinary Science. Department of Forestry; EtiopíaFil: King, Oliver I. M.S. Swaminathan Research Foundation; IndiaFil: Mbosso, C. Bioversity International; ItaliaFil: Padulosi, Stefano. Bioversity International; ItaliaFil: Speelman, Erika N. Wageningen University & Research. Laboratory of Geo-information Science and Remote Sensing; Países BajosFil: van Noordwijk, Meine. World Agroforestry (ICRAF); IndonesiaFil: van Noordwijk, Meine. Wageningen University & Research. Plant Production Systems; Países Bajo

    Reduction in the QRS area after cardiac resynchronization therapy is associated with survival and echocardiographic response

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    Introduction Recent studies have shown that the baseline QRS area is associated with the clinical response after cardiac resynchronization therapy (CRT). In this study, we investigated the association of QRS area reduction ( increment QRS area) after CRT with the outcome. We hypothesize that a larger increment QRS area is associated with a better survival and echocardiographic response. Methods and Results Electrocardiograms (ECG) obtained before and 2-12 months after CRT from 1299 patients in a multi-center CRT-registry were analyzed. The QRS area was calculated from vectorcardiograms that were synthesized from 12-lead ECGs. The primary endpoint was a combination of all-cause mortality, heart transplantation, and left ventricular (LV) assist device implantation. The secondary endpoint was the echocardiographic response, defined as LV end-systolic volume reduction >= of 15%. Patients with increment QRS area above the optimal cut-off value (62 mu Vs) had a lower risk of reaching the primary endpoint (hazard ratio: 0.43; confidence interval [CI] 0.33-0.56, p = 109 mu Vs, survival, and echocardiographic response were better when the increment QRS area was >= 62 mu Vs (p = 109 mu Vs, increment QRS area was the only significant predictor of survival (OR: 0.981; CI: 0.967-0.994, p = .006). Conclusion increment QRS area is an independent determinant of CRT response, especially in patients with a large baseline QRS area. Failure to achieve a large QRS area reduction with CRT is associated with a poor clinical outcome

    Implementing water policies in China: A policy cycle analysis of the Sponge City Program using two case studies

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    This study carries out an in-depth analysis of urban water policy implementation in China through a policy cycle analysis and case study of Sponge city program. The policy cycle analysis articulates discrete steps within the policy formulation and implementation process, while the case studies reflect the specific problems in water project implementation. Because of the principal-agent relation between central and local government, a "double wheel" policy cycle model is adopted to reflect the policy cycles at central level and at local level. Changde city and Zhuanghe city, two demo cities in the Sponge city program, are chosen for the analysis. The policy cycle analysis shows that the central government orders local government to implement policy without clear direction on how to attract private sector participation. The evaluation of central government did not include private sector involvement, nor the sustainability of the investments. This promotes the local government's pursuit of project construction completion objectives, without seriously considering private sector involvement and operation and maintenance (O&M) cost. The local governments do not have political motivation and experiences to attract private investments into project implementation. The case study in the two demo cities shows that local government subsidies are the main source of O&M funding currently, which is not sustainable. The water projects are not financially feasible because no sufficient revenue is generated to cover the high initial investments and O&M cost. The lack of private sector involvement makes it difficult t

    Climate-smart land use requires local solutions, transdisciplinary research, policy coherence and transparency

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    Successfully meeting the mitigation and adaptation targets of the Paris Climate Agreement (PA) will depend on strengthening the ties between forests and agriculture. Climate-smart land use can be achieved by integrating climate-smart agriculture (CSA) and REDD+. The focus on agriculture for food security within a changing climate, and on forests for climate change mitigation and adaptation, can be achieved simultaneously with a transformational change in the land-use sector. Striving for both independently will lead to competition for land, inefficiencies in monitoring and conflicting agendas. Practical solutions exist for specific contexts that can lead to increased agricultural output and forest protection. Landscape-level emissions accounting can be used to identify these practices. Transdisciplinary research agendas can identify and prioritize solutions and targets for integrated mitigation and adaptation interventions. Policy coherence must be achieved at a number of levels, from international to local, to avoid conflicting incentives. Transparency must lastly be integrated, through collaborative design of projects, and open data and methods. Climate-smart land use requires all these elements, and will increase the likelihood of successful REDD+ and CSA interventions. This will support the PA as well as other initiatives as part of the Sustainable Development Goals
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