The role of body size on the outcome of mating interactions in Drosophila melanogaster

Sexual selection is the process by which some individuals produce more and/or better quality offspring than others because they are better at securing mates. While this may be accomplished by defeating same-sex rivals (intrasexual selection), individuals of one sex (typically females) may also “decide” on the suitability of individuals of the opposite sex (typically males), resulting in intersexual selection on attractive traits. While a great deal of scrutiny has focused on how sexual selection influences male display traits, much less scrutiny has been directed toward the factors underlying female preference, including genetic variation, as well as the extent to which both sexes are involved in mate choice. In Drosophila melanogaster, a model species for the study of sexual selection, previous studies have examined the role of body size variation in a single sex on the behaviours and outcomes related to courtship and copulation. However, few studies have simultaneously varied both male and female body size. In my first study (Chapter 2), I experimentally paired male and female flies from across a wide spectrum of body size phenotypes and quantified several behavioural traits: time to courtship initiation, length of courtship and length of copulation. I found that absolute body size differences affected length of courtship and that relative body size differences affected time to courtship initiation. While Chapter 2 demonstrated how mate choice may be expressed within a single generation of individuals, whether individual preference variation in females had a genetic component had yet to be determined experimentally. In my second study (Chapter 3), I investigated if female body size preference had a genetic component by directly selecting on female preference over multiple generations. Using artificial selection, I “penalized” females that mated with males of certain body sizes over 20 generations and observed several significant differences in female preference behaviour. In all treatments, females tended to associate significantly more with males of body sizes different from those they were artificially selected against. These results not only suggest that body size in both sexes can significantly influence female preference behaviours, but that body size may be a trait possessing significant genetic variation with the potential to be strongly shaped by sexual selection

Multiple regions of quantum criticality in YbAgGe

Dilation and thermopower measurements on YbAgGe, a heavy-fermion antiferromagnet, clarify and refine the magnetic field-temperature (H-T) phase diagram and reveal a field-induced phase with T-linear resistivity. On the low-H side of this phase we find evidence for a first-order transition and suggest that YbAgGe at 4.5 T may be close to a quantum critical end point. On the high-H side our results are consistent with a second-order transition suppressed to a quantum critical point near 7.2 T. We discuss these results in light of global phase diagrams proposed for Kondo lattice systems

A versatile and compact capacitive dilatometer

We describe the design, construction, calibration, and operation of a relatively simple differential capacitive dilatometer suitable for measurements of thermal expansion and magnetostriction from 300 K to below 1 K with a low-temperature resolution of about 0.05 angstroms. The design is characterized by an open architecture permitting measurements on small samples with a variety of shapes. Dilatometers of this design have operated successfully with a commercial physical property measurement system, with several types of cryogenic refrigeration systems, in vacuum, in helium exchange gas, and while immersed in liquid helium (magnetostriction only) to temperatures of 30 mK and in magnetic fields to 45 T.Comment: 8 pages, incorporating 6 figures, submitted to Rev. Sci. Instru

Examination of change factor methodologies for climate change impact assessment

Citation: Anandhi, A., Frei, A., Pierson, D. C., Schneiderman, E. M., Zion, M. S., Lounsbury, D., and Matonse, A. H. ( 2011), Examination of change factor methodologies for climate change impact assessment, Water Resour. Res., 47, W03501, doi:10.1029/2010WR009104.A variety of methods are available to estimate values of meteorological variables at future times and at spatial scales that are appropriate for local climate change impact assessment. One commonly used method is Change Factor Methodology (CFM), sometimes referred to as delta change factor methodology. Although more sophisticated methods exist, CFM is still widely applicable and used in impact analysis studies. While there are a number of different ways by which change factors (CFs) can be calculated and used to estimate future climate scenarios, there are no clear guidelines available in the literature to decide which methodologies are most suitable for different applications. In this study several categories of CFM (additive versus multiplicative and single versus multiple) for a number of climate variables are compared and contrasted. The study employs several theoretical case studies, as well as a real example from Cannonsville watershed, which supplies water to New York City, USA. Results show that in cases when the frequency distribution of Global Climate Model (GCM) baseline climate is close to the frequency distribution of observed climate, or when the frequency distribution of GCM future climate is close to the frequency distribution of GCM baseline climate, additive and multiplicative single CFMs provide comparable results. Two options to guide the choice of CFM are suggested. The first option is a detailed methodological analysis for choosing the most appropriate CFM. The second option is a default method for use under circumstances in which a detailed methodological analysis is too cumbersome

Green roofs for stormwater runoff retention: a global quantitative synthesis of the performance

The global popularity of green roofs (GRs) rises as urban runoff becomes a primary environmental concern in both developed and developing countries. Although a growing number of studies have measured the runoff retention (RR) performance of GRs and investigated the underpinning factors, a systematic and quantitative understanding is lacking. This study applies a statistical approach on a dataset of 2375 original experimental samples associated with the RR performance of GRs observed across 21 countries, consolidated from 75 internationally peer-reviewed studies published in 2005–2020. The results show that the sampled RR rates (i.e., the proportion of rainfall retained on a per-event basis) range widely (0–100%), with an average of 62%. Rainfall intensity, substrate depth, GR surface coverage, climate type, vegetation type, and season type partially explain the variances in retention performance. Moreover, the effects of some factors (e.g., rainfall intensity) are not isolated but contingent on other factors (e.g., vegetative cover). This global synthesis shows few samples emanate from Africa, Central America, and Central Asia, highlighting the need of more GR research and applications in these regions. The average GR RR rate appears lower than some specified in green building standards, which implies the need to further improve the RR performance of GRs or combine GRs with other RR measures. Contingent effects of GR RR influencing factors demonstrate the need to leverage design parameters and to account for local weather and climate characteristics in the optimization of GR performance.Industrial Ecolog

Performative Work: Bridging Performativity and Institutional Theory in the Responsible Investment Field

Callon’s performativity thesis has illuminated how economic theories and calculative devices shape markets, but has been challenged for its neglect of the organizational, institutional and political context. Our seven-year qualitative study of a large financial data company found that the company’s initial attempt to change the responsible investment field through a performative approach failed because of the constraints posed by field practices and organizational norms on the design of the calculative device. However, the company was subsequently able to put in place another form of performativity by attending to the normative and regulative associations of the device. We theorize this route to performativity by proposing the concept of performative work, which designates the necessary institutional work to enable translation and the subsequent adoption of the device. We conclude by considering the implications of performative work for the performativity and the institutional work literatures

Entrepreneurial sons, patriarchy and the Colonels' experiment in Thessaly, rural Greece

Existing studies within the field of institutional entrepreneurship explore how entrepreneurs influence change in economic institutions. This paper turns the attention of scholarly inquiry on the antecedents of deinstitutionalization and more specifically, the influence of entrepreneurship in shaping social institutions such as patriarchy. The paper draws from the findings of ethnographic work in two Greek lowland village communities during the military Dictatorship (1967–1974). Paradoxically this era associated with the spread of mechanization, cheap credit, revaluation of labour and clear means-ends relations, signalled entrepreneurial sons’ individuated dissent and activism who were now able to question the Patriarch’s authority, recognize opportunities and act as unintentional agents of deinstitutionalization. A ‘different’ model of institutional change is presented here, where politics intersects with entrepreneurs, in changing social institutions. This model discusses the external drivers of institutional atrophy and how handling dissensus (and its varieties over historical time) is instrumental in enabling institutional entrepreneurship

Perceptions of Cancer Risk/Efficacy and Cancer-Related Risk Behaviors : Results From the HCHS/SOL Sociocultural Ancillary Study

This study evaluated the associations among perceived risk, perceived efficacy, and engagement in six cancer-related risk behaviors in a population-based Hispanic/Latino sample. Interviews were conducted with 5,313 Hispanic/Latino adults as part of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Sociocultural Ancillary Study. Participants were recruited from the study's four field centers (Bronx, NY; Chicago, IL; Miami, FL; San Diego, CA) between February 2010 and June 2011. Perceived risk and perceived efficacy were assessed with questions drawn from the Health Interview National Trends Survey. More than half of the sample endorsed perceived risk of cancer associated with the six evaluated behaviors, as well as general perceived efficacy for preventing cancer. Adjusted logistic regression analyses demonstrated significant differences across Hispanic/Latino background groups for perceived risk associated with high consumption of alcohol and saturated fat, low consumption of fruits and vegetables, and insufficient exercise but not with smoking or low consumption of fiber. Differences were also found for the belief, "It seems like everything causes cancer" but not for other perceived efficacy items. Perceived cancer risk and perceived efficacy for preventing cancer were neither independently nor interactively associated with engagement in cancer-related risk behaviors after controlling for sociodemographic covariates. Results suggest that perceptions of risk and efficacy with regard to cancer vary across Hispanic/Latino background groups, and therefore background group differences should be considered in prevention efforts. Perceived risk and perceived efficacy were not related to cancer-related risk behaviors among Hispanics/Latinos. Further work is needed to evaluate determinants of cancer-related risk in this population

Efficacy and safety of enzyme replacement therapy with BMN 110 (elosulfase alfa) for Morquio A syndrome (mucopolysaccharidosis IVA): a phase 3 randomised placebo-controlled study.

ObjectiveTo assess the efficacy and safety of enzyme replacement therapy (ERT) with BMN 110 (elosulfase alfa) in patients with Morquio A syndrome (mucopolysaccharidosis IVA).MethodsPatients with Morquio A aged ≥5 years (N = 176) were randomised (1:1:1) to receive elosulfase alfa 2.0 mg/kg/every other week (qow), elosulfase alfa 2.0 mg/kg/week (weekly) or placebo for 24 weeks in this phase 3, double-blind, randomised study. The primary efficacy measure was 6-min walk test (6MWT) distance. Secondary efficacy measures were 3-min stair climb test (3MSCT) followed by change in urine keratan sulfate (KS). Various exploratory measures included respiratory function tests. Patient safety was also evaluated.ResultsAt week 24, the estimated mean effect on the 6MWT versus placebo was 22.5 m (95 % CI 4.0, 40.9; P = 0.017) for weekly and 0.5 m (95 % CI -17.8, 18.9; P = 0.954) for qow. The estimated mean effect on 3MSCT was 1.1 stairs/min (95 % CI -2.1, 4.4; P = 0.494) for weekly and -0.5 stairs/min (95 % CI -3.7, 2.8; P = 0.778) for qow. Normalised urine KS was reduced at 24 weeks in both regimens. In the weekly dose group, 22.4 % of patients had adverse events leading to an infusion interruption/discontinuation requiring medical intervention (only 1.3 % of all infusions in this group) over 6 months. No adverse events led to permanent treatment discontinuation.ConclusionsElosulfase alfa improved endurance as measured by the 6MWT in the weekly but not qow dose group, did not improve endurance on the 3MSCT, reduced urine KS, and had an acceptable safety profile

Motivations for innovation in the built environment: new directions for research

Innovation in the built environment involves multiple actors with diverse motivations. Policy-makers find it difficult to promote changes that require cooperation from these numerous and dispersed actors and to align their sometimes divergent interests. Established research traditions on the economics and management of innovation pay only limited attention to stakeholder choices, engagement and motivation. This paper reviews the insights that emerge as research in these traditions comes into contact with work on innovation from sociological and political perspectives. It contributes by highlighting growing areas of research on user involvement in complex innovation, collective action, distributed innovation and transition management. To differing extents, these provide approaches to incorporate the motivations of different actors into theoretical understanding. These indicate new directions for research that promise to enrich understanding of innovation