156 research outputs found

    The expanding role of quantitative methodologists in advancing psychology

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    Research designs in psychology have become increasingly complex; thus, the methods for analysing the data have also become more complex. It is unrealistic for departments of psychology to expect research psychologists to stay informed about all the advances in statistical methods that apply to their field of research; therefore, departments must improve the profile of quantitative methods to ensure that adequate statistical resources are available to faculty. In this article, we discuss the challenges involved in improving the profile of quantitative methods given the drastic decreases in quantitative methods faculty, students, and graduate programs over the past couple decades, and discuss the importance of reversing. this trend through improving awareness of the field of quantitative methods in psychologySocial Sciences and Humanities Research Council (SSHRC

    Free Radicals, Salicylic Acid and Mycotoxins in Asparagus After Inoculation with Fusarium proliferatum and F. oxysporum

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    Electron paramagnetic resonance was used to monitor free radicals and paramagnetic species like Fe, Mn, Cu generation, stability and status in Asparagus officinalis infected by common pathogens Fusarium proliferatum and F. oxysporum. Occurrence of F. proliferatum and F. oxysporum, level of free radicals and other paramagnetic species, as well as salicylic acid and mycotoxins content in roots and stems of seedlings were estimated on the second and fourth week after inoculation. In the first term free and total salicylic acid contents were related to free radicals level in stem (P = 0.010 and P = 0.033, respectively). Concentration of Fe3+ ions in porphyrin complexes (g = 2.3, g = 2.9) was related to the species of pathogen. There was no significant difference between Mn2+ concentrations in stem samples; however, the level of free radicals in samples inoculated with F. proliferatum was significantly higher when compared to F. oxysporum

    Climate and colonialism

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    Recent years have seen a growth in scholarship on the intertwined histories of climate, science and European imperialism. Scholarship has focused both on how the material realities of climate shaped colonial enterprises, and on how ideas about climate informed imperial ideologies. Historians have shown how European expansion was justified by its protagonists with theories of racial superiority, which were often closely tied to ideas of climatic determinism. Meanwhile, the colonial spaces established by European powers offered novel ‘laboratories’ where ideas about acclimatisation and climatic improvement could be tested on the ground. While historical scholarship has focused on how powerful ideas of climate informed imperial projects, emerging scholarship in environmental history, history of science and historical geography focuses instead on the material and cognitive practices by which the climates of colonial spaces were made known and dealt with in fields such as forestry, agriculture and human health. These heretofore rather disparate areas of historical research carry great contemporary relevance of studies of how climates and their changes have been understood, debated and adapted to in the past

    Adrenal function recovery after durable oral corticosteroid sparing with benralizumab in the PONENTE study

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    Background Oral corticosteroid (OCS) dependence among patients with severe eosinophilic asthma can cause adverse outcomes, including adrenal insufficiency. PONENTE's OCS reduction phase showed that, following benralizumab initiation, 91.5% of patients eliminated corticosteroids or achieved a final dosage ≀5 mg·day-1 (median (range) 0.0 (0.0-40.0) mg). Methods The maintenance phase assessed the durability of corticosteroid reduction and further adrenal function recovery. For ~6 months, patients continued benralizumab 30 mg every 8 weeks without corticosteroids or with the final dosage achieved during the reduction phase. Investigators could prescribe corticosteroids for asthma exacerbations or increase daily dosages for asthma control deteriorations. Outcomes included changes in daily OCS dosage, Asthma Control Questionnaire (ACQ)-6 and St George's Respiratory Questionnaire (SGRQ), as well as adrenal status, asthma exacerbations and adverse events. Results 598 patients entered PONENTE; 563 (94.1%) completed the reduction phase and entered the maintenance phase. From the end of reduction to the end of maintenance, the median (range) OCS dosage was unchanged (0.0 (0.0-40.0) mg), 3.2% (n=18/563) of patients experienced daily dosage increases, the mean ACQ-6 score decreased from 1.26 to 1.18 and 84.5% (n=476/563) of patients were exacerbation free. The mean SGRQ improvement (-19.65 points) from baseline to the end of maintenance indicated substantial quality-of-life improvements. Of patients entering the maintenance phase with adrenal insufficiency, 32.4% (n=104/321) demonstrated an improvement in adrenal function. Adverse events were consistent with previous reports. Conclusions Most patients successfully maintained maximal OCS reduction while achieving improved asthma control with few exacerbations and maintaining or recovering adrenal function

    Chemistry and the Science of Transformation in Mary Shelley’s Frankenstein

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    This essay reads the novel in a new way, examining the way that Victor Frankenstein's chemical education (he does not train to be a doctor!) enables his creation of the monster. It reveals that chemists of the period had a different worldview to others where they saw the world in constant transformation and flux. I have written this essay co-written the introduction to the special issue, and co-edited the whole

    Epistemic geographies of climate change: science, space and politics

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    Anthropogenic climate change has been presented as the archetypal global problem, identified by the slow work of assembling a global knowledge infrastructure, and demanding a concertedly global political response. But this ‘global’ knowledge has distinctive geographies, shaped by histories of exploration and colonialism, by diverse epistemic and material cultures of knowledge-making, and by the often messy processes of linking scientific knowledge to decision-making within different polities. We suggest that understanding of the knowledge politics of climate change may benefit from engagement with literature on the geographies of science. We review work from across the social sciences which resonates with geographers’ interests in the spatialities of scientific knowledge, to build a picture of what we call the epistemic geographies of climate change. Moving from the field site and the computer model to the conference room and international political negotiations, we examine the spatialities of the interactional co-production of knowledge and social order. In so doing, we aim to proffer a new approach to the intersections of space, knowledge and power which can enrich geography’s engagements with the politics of a changing climate
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