Propuesta didáctica para el aprendizaje en el laboratorio basado en resolución de problemas reales

Mejorar la actividad experimental para la enseñanza de la física en la formación del profesorado es un reto. Del análisis de las diferentes maneras de abordar el trabajo experimental, y la caracterización de los tipos de trabajo de laboratorio con fines educativos concluimos que las actividades experimentales son importantes en la enseñanza de la física, y que conviene proponer distintos tipos de laboratorio. Además, promover el aprendizaje integrando lo teórico y lo metodológico, cosa que no se logra en el laboratorio tradicional. Proponemos una estrategia didáctica para el aprendizaje de la física en el laboratorio basado en la resolución de problemas contextualizados en situaciones reales, dada su potencialidad para el desarrollo conceptual, metodológico y epistemológico

Propuesta didáctica para el aprendizaje en el laboratorio basado en resolución de problemas reales

Mejorar la actividad experimental para la enseñanza de la física en la formación del profesorado es un reto. Del análisis de las diferentes maneras de abordar el trabajo experimental, y la caracterización de los tipos de trabajo de laboratorio con fines educativos concluimos que las actividades experimentales son importantes en la enseñanza de la física, y que conviene proponer distintos tipos de laboratorio. Además, promover el aprendizaje integrando lo teórico y lo metodológico, cosa que no se logra en el laboratorio tradicional. Proponemos una estrategia didáctica para el aprendizaje de la física en el laboratorio basado en la resolución de problemas contextualizados en situaciones reales, dada su potencialidad para el desarrollo conceptual, metodológico y epistemológico

Mesozooplankton from Ría de Vigo (NW Spain) and its adjacent shelf between 1995 and 2003

The mesozooplankton (200 μm to 2 mm) community from monthly samples collected at two stations in Ría de Vigo (39 m) and its adjacent shelf (97 m) between 1995-2003 is described. The mesozooplankton was dominated by copepods. Inside the Ría, meroplankton (larvae of gasteropods, lamelibranchiae, echinodermate and cirripids nauplii) and other holoplanktonic organisms, such as apendicularia, cladocera, siphonophora and medusae, were also well represented. The copepod group inside the Ría was dominated by Acartia clausi, juveniles of Calanus helgolandicus, Paracalanus parvus, Pseudocalanus elongatus, Temora longicornis, Oithona plumifera, Oncaea media, Euterpina acutifrons and copepodites of Centropages spp. In the offshore station, dominant copepods species were the same than inshore together with other oceanic species, such as Paraeuchaeta hebes, Calanoides carinatus and Aetideus armatus. Biomass values within Ría de Vigo ranged between 2 and 151 mg dry weight /m3 and between 2 and 314 mg dry weight /m3 in the offshore station. Abundance ranged between 149 ind/m in January 1995 and 41814 ind/m3 in August of 2003 in the inner station, and between 22 ind/m3 in January 1996 and 93410 ind/m3 in May 1999 in the outer station. The most outstanding events were the high levels of the Mediterranean copepod Temora stylifera, usually rare in Galician waters recorded in the area in 1997 and 1998, and the increased levels of cirripid larvae observed inside the Ría

Rapid detection and identification of strains carrying carbapenemases directly from positive blood cultures using MALDI-TOF MS

MALDI-TOF MS has been evaluated to detect carbapenemases activity and pathogen identification directly from positive blood cultures. 21 non-carbapenemase producers and 19 carbapenemase producers Enterobacteriaceae and Pseudomonas aeruginosa strains were included in the study. This technique is simple and detects carbapenemases in 4.5h with high sensitivity and specificity

Evaluación de las necesidades hídricas de tres variedades de fresas y de su respuesta frente a un recorte hídrico moderado

Instituto Nacional de Investigaciones RTA2012-00001-00-00FEDER CC10-009-C02-0

Paragonimus y Paragonimiasis en el norte peruano. Proceso del desarrollo de Paragonimus peruvianus Miyazaki¡ Ibañez y Miranda¡ 1969 en Felis cati L. gato doméstico infectado experimentalmente.

The process of the development of Parogonimus peruvianus Miyazaki, Ibóñez y Miranda, 1969 in domestic cat Felis cati L. experimentally infected by means of orally given metacercarias extracted from specimens of Pseudothelphusa chilen.is Milne Edwards, 1843 from endemic areas, has been studied.Se ha estudiado el proceso del desarrollo de Parogonimus peruvianus Miyazaki, Ibóñez y Miranda, 1969 en el gato doméstico, Felis cati L. infectado experimentalmente mediante la administración oral de metacercarias del parasito extraídas de ejemplares de Pseudothelphusa chilensis Milne Edwards, 1843 procedentes de áreas endémicas

Understanding Parents\u27 Views toward the Newly Enacted HPV Vaccine School Entry Policy in Puerto Rico: A Qualitative Study

BACKGROUND: The Human papillomavirus vaccine (HPV) is an essential tool for the prevention of HPV-related cancers. In Puerto Rico, the Secretary of Health established a school entry requirement of at least one dose of HPV vaccination in girls and boys aged 11 and 12 years, taking effect in August 2018. Our study aimed to examine parents\u27 and guardians\u27 views of unvaccinated children about the process of implementation of the new HPV vaccination school entry policy in Puerto Rico and identify potential barriers and facilitators related to the implementation of this requirement. METHODS: During April through November 2019, we conducted three focus groups (n = 12) and eight in-depth semi-structured interviews with parents of children aged 11 and 12 who had not yet initiated the HPV vaccine series. The interview topics addressed were: perception of vaccination, HPV vaccine and it is inclusion as new school entry requirement practice, procedure of the sources of information, influencers, and willingness to change. The interviews were recorded and transcribed by our staff members. We identified emergent themes through thematic analysis. RESULTS: The participants\u27 perspective on the HPV vaccine school requirement was mixed. Lack of information of the HPV vaccines and lack of communication about the school-entry requirement were the themes most mentioned in the interviews. Moreover, previous negative experiences from friends or family members and adverse effects deterred some participants from vaccinating their kids. We discussed barriers in the process of soliciting an exemption. CONCLUSION: Most barriers mentioned by study participants are modifiable. Information about the HPV vaccine mandate\u27s implementation and educational materials regarding HPV vaccine safety need to be provided to address parents\u27 concerns related to the vaccine\u27s side effects. Schools (teachers, principal directors, and administrative staff), the government, and parent organizations need to be part of these efforts. This multilevel approach will help to improve disseminating information about HPV vaccination to clarify doubts and misinformation among parents

Long-slit spectroscopy and direct imaging of the PMS objects GGD-33 and V-350 cephei in NGC-7129

We present CCD images and long-slit spectra of the nebulous object GGD 33 and of the T Tauri star V 350 Cep in the star formation region NGC 7129. The data suggest that GGD 33a is a T Tauri star and likely the illuminating source of the whole GGD 33. Evidence of variability of GGD 33a is presented. Double-peaked [S II] emission lines are observed in GGD 33a. The high-velocity component of the [S II] emission could be related to a HH jet-like outflow observed very close to the star. V 350 Cep is embedded in a reflection nebulosity. High velocity mass outflow, detected through its blueshifted Halpha emission, seems to emanate from V 350 Cep. The spectrum of V 350 Cep presents a large number of permitted emission lines, but, except [S II], no forbidden emission lines have been identified in our spectra

Genes and lipids that impact uptake and assimilation of exogenous coenzyme Q in Saccharomyces cerevisiae.

Coenzyme Q (CoQ) is an essential player in the respiratory electron transport chain and is the only lipid-soluble antioxidant synthesized endogenously in mammalian and yeast cells. In humans, genetic mutations, pathologies, certain medical treatments, and aging, result in CoQ deficiencies, which are linked to mitochondrial, cardiovascular, and neurodegenerative diseases. The only strategy available for these patients is CoQ supplementation. CoQ supplements benefit a small subset of patients, but the poor solubility of CoQ greatly limits treatment efficacy. Consequently, the efficient delivery of CoQ to the mitochondria and restoration of respiratory function remains a major challenge. A better understanding of CoQ uptake and mitochondrial delivery is crucial to make this molecule a more efficient and effective therapeutic tool. In this study, we investigated the mechanism of CoQ uptake and distribution using the yeast Saccharomyces cerevisiae as a model organism. The addition of exogenous CoQ was tested for the ability to restore growth on non-fermentable medium in several strains that lack CoQ synthesis (coq mutants). Surprisingly, we discovered that the presence of CoQ biosynthetic intermediates impairs assimilation of CoQ into a functional respiratory chain in yeast cells. Moreover, a screen of 40 gene deletions considered to be candidates to prevent exogenous CoQ from rescuing growth of the CoQ-less coq2Δ mutant, identified six novel genes (CDC10, RTS1, RVS161, RVS167, VPS1, and NAT3) as necessary for efficient trafficking of CoQ to mitochondria. The proteins encoded by these genes represent essential steps in the pathways responsible for transport of exogenously supplied CoQ to its functional sites in the cell, and definitively associate CoQ distribution with endocytosis and intracellular vesicular trafficking pathways conserved from yeast to human cells