Change Management in Large-Scale Enterprise Information Systems

Abstract. The information infrastructure in today’s businesses consists of many interoperating autonomous systems. Changes to a single system can therefore have an unexpected impact on other, dependent systems. In our Caro approach we try to cope with this problem by observing each system participating in the infrastructure and analyzing the impact of any change that occurs. The analysis process is driven by declaratively defined rules and works with a generic and ex-tensible graph model to represent the relevant metadata that is subject to changes. This makes Caro applicable to heterogeneous scenarios and customizable to spe-cial needs.

Identification and quantification of phenolic compounds in bambangan (Mangifera pajang Kort.) peels and their free radical scavenging activity.

Phenolic compounds and antioxidant capacity of acidified methanolic extract prepared from fully ripe bambangan (Mangifera pajang K.) peel cultivated in Sarawak, Malaysia, were analyzed. The total phenolic content (98.3 mg GAE/g) of bambangan peel powder (BPP) was determined by the Folin-Ciocalteu method. BPP showed a strong potency of antioxidant activity and was consistent with that of BHT and vitamin C as confirmed by the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity and FRAP (ferric-reducing antioxidant power) assays. Gallic acid, p-coumaric acid, ellagic acid, protocatechuic acid, and mangiferin were the major compounds among the 16 phenolics that have been identified and quantified in M. pajang peels with 20.9, 12.7, 7.3, 5.4, and 4.8 mg/g BPP, respectively. Peak identities were confirmed by comparing their retention times, UV-vis absorption spectra, and mass spectra with authentic standards. The 16 phenolic compounds identified in M. pajang K. using HPLC-DAD and TSQ-ESI-MS are reported here for the first time

Early Life Child Micronutrient Status, Maternal Reasoning, and a Nurturing Household Environment have Persistent Influences on Child Cognitive Development at Age 5 years : Results from MAL-ED

Funding Information: The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development Project (MAL-ED) is carried out as a collaborative project supported by the Bill & Melinda Gates Foundation, the Foundation for the NIH, and the National Institutes of Health/Fogarty International Center. This work was also supported by the Fogarty International Center, National Institutes of Health (D43-TW009359 to ETR). Author disclosures: BJJM, SAR, LEC, LLP, JCS, BK, RR, RS, ES, LB, ZR, AM, RS, BN, SH, MR, RO, ETR, and LEM-K, no conflicts of interest. Supplemental Tables 1–5 and Supplemental Figures 1–3 are available from the “Supplementary data” link in the online posting of the article and from the same link in the online table of contents at https://academic.oup.com/jn/. Address correspondence to LEM-K (e-mail: [email protected]). Abbreviations used: HOME, Home Observation for Measurement of the Environment inventory; MAL-ED, The Etiology, Risk Factors, and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development Project; TfR, transferrin receptor; WPPSI, Wechsler Preschool Primary Scales of Intelligence.Peer reviewe

Early life child micronutrient status, maternal reasoning, and a nurturing household environment have persistent influences on child cognitive development at age 5 years: Results from MAL-ED

Background: Child cognitive development is influenced by early-life insults and protective factors. To what extent these factors have a long-term legacy on child development and hence fulfillment of cognitive potential is unknown. Objective: The aim of this study was to examine the relation between early-life factors (birth to 2 y) and cognitive development at 5 y. Methods: Observational follow-up visits were made of children at 5 y, previously enrolled in the community-based MAL-ED longitudinal cohort. The burden of enteropathogens, prevalence of illness, complementary diet intake, micronutrient status, and household and maternal factors from birth to 2 y were extensively measured and their relation with the Wechsler Preschool Primary Scales of Intelligence at 5 y was examined through use of linear regression. Results: Cognitive T-scores from 813 of 1198 (68%) children were examined and 5 variables had significant associations in multivariable models: mean child plasma transferrin receptor concentration (β: −1.81, 95% CI: −2.75, −0.86), number of years of maternal education (β: 0.27, 95% CI: 0.08, 0.45), maternal cognitive reasoning score (β: 0.09, 95% CI: 0.03, 0.15), household assets score (β: 0.64, 95% CI: 0.24, 1.04), and HOME child cleanliness factor (β: 0.60, 95% CI: 0.05, 1.15). In multivariable models, the mean rate of enteropathogen detections, burden of illness, and complementary food intakes between birth and 2 y were not significantly related to 5-y cognition. Conclusions: A nurturing home context in terms of a healthy/clean environment and household wealth, provision of adequate micronutrients, maternal education, and cognitive reasoning have a strong and persistent influence on child cognitive development. Efforts addressing aspects of poverty around micronutrient status, nurturing caregiving, and enabling home environments are likely to have lasting positive impacts on child cognitive development.publishedVersio

Using model transformation semantics for aspects composition

In this paper we present aspect composition using model transformation language - ATL. The aspects are represented as UML sequence diagrams. We propose and implement complete composition algorithm using three ATL transformation models - JoinPointsCount, Instantiate, and Compose. The JoinPointsCount transformation determines the number of join points in the primary (core system) model. The Instantiate transformation is used to instantiate generic aspect models in the context of the application using a set of binding rules defined in mark models to produce context specific aspect models. The Compose transformation then takes the primary model and context specific aspect model as inputs, and produces a composed (integrated) model

Support mechanisms for cloud configuration using XML filtering techniques: A case study in SaaS

Software-as-a-service (SaaS) has attracted substantial attention as a software delivery and service model in a cloud computing environment. SaaS delivery can help organizations significantly reduce the cost of using software, because the resources for running SaaS applications are shared among tenants (end users or organizations). However, multi-tenancy can considerably complicate SaaS development, deployment, and maintenance as a result of a large number of co-existing tenant-specific constraints or features. Manually configuring and maintaining tenant-specific features will increase the cost, introduce possible errors, and limit scalability and flexibility. The paper addresses the problem of large variations and complex configurations. Specifically, the objective is to develop mechanisms to support automatic multi-tenant software features analysis and matching for the purposes of efficient deployment and operations in the cloud. The emphasis of this paper is on the matching between the tenant-specific requirements and the SaaS features managed by the cloud provider. This paper proposes a novel approach for cloud feature matching using XML filtering techniques to support the process of multi-tenant SaaS deployment and management. Feature modeling has been widely used to capture requirements and constraints. On the other hand, XML filtering techniques are mature and have been adopted in various problem domains. We used Yfilter, a proven and XML filtering technique, to support two multi-tenant applications: (i) Identifying SaaS configurations (in XPath representations) that satisfy tenant-specific requirements and constraints (in XML notation); and (ii) Identifying tenants that have subscribed to a specific set of SaaS features. The applications can effectively facilitate SaaS subsequent management and operations due to various changes, e.g., functionalities, constraints, cost, etc. The experimental results demonstrate that the proposed approach can automatically and correctly identify cloud system configurations that match tenant-specif