Trypanosoma cruzi: Seroprevalence Detection in Suburban Population of Santiago de Querétaro (Mexico)

Objectives. To evaluate the potential of iron-oxide dismutase excreted (SODeCRU) by T. cruzi as the antigen fraction in the serodiagnosis of Chagas disease and compile new epidemiological data on the seroprevalence of this disease in the suburban population of the city of Santiago de Querétaro (Mexico). Design and Methods. 258 human sera were analyzed by the techniques of ELISA and Western blot and using the homogenate and the SODeCRU. Results. A total of 31 sera were positive against ELISA/SODeCRU (12.4%), while 30 sera proved positive by WB/SODeCRU (11.6%). The comparison between the technique of ELISA and WB showed a sensitivity of 93%, and a specificity of 99%. The positive predictive value was 93% and the negative predictive value was 99%, with a Kappa (κ) value of 1. Conclusions. These preliminary data reveal the degree of infection of nonrural areas of Mexico and demonstrated that SODeCRU is an antigen useful to diagnose Chagas disease

Carta que el cardenal Astorga, Arzobispo de Toledo ... escriviò à ... Clemente XII remitiendo los processos hechos en estos reynos ... para la beatificacion del V. maestro Juan de Avila ...y para que la noticia de las admirables virtudes... de este gran Siervo de Dios sirva de exhortación pastoral a los fieles de este Arzobispado ...

Copia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 2009-2010Texto fechado en Madrid, Agosto 15 de 1731Sign.: A-G2Capital grabada xilográfic

Autoantibodies against type I IFNs in patients with critical influenza pneumonia

In an international cohort of 279 patients with hypoxemic influenza pneumonia, we identified 13 patients (4.6%) with autoantibodies neutralizing IFN-alpha and/or -omega, which were previously reported to underlie 15% cases of life-threatening COVID-19 pneumonia and one third of severe adverse reactions to live-attenuated yellow fever vaccine. Autoantibodies neutralizing type I interferons (IFNs) can underlie critical COVID-19 pneumonia and yellow fever vaccine disease. We report here on 13 patients harboring autoantibodies neutralizing IFN-alpha 2 alone (five patients) or with IFN-omega (eight patients) from a cohort of 279 patients (4.7%) aged 6-73 yr with critical influenza pneumonia. Nine and four patients had antibodies neutralizing high and low concentrations, respectively, of IFN-alpha 2, and six and two patients had antibodies neutralizing high and low concentrations, respectively, of IFN-omega. The patients' autoantibodies increased influenza A virus replication in both A549 cells and reconstituted human airway epithelia. The prevalence of these antibodies was significantly higher than that in the general population for patients 70 yr of age (3.1 vs. 4.4%, P = 0.68). The risk of critical influenza was highest in patients with antibodies neutralizing high concentrations of both IFN-alpha 2 and IFN-omega (OR = 11.7, P = 1.3 x 10(-5)), especially those <70 yr old (OR = 139.9, P = 3.1 x 10(-10)). We also identified 10 patients in additional influenza patient cohorts. Autoantibodies neutralizing type I IFNs account for similar to 5% of cases of life-threatening influenza pneumonia in patients <70 yr old

Com o diabo no corpo: os terríveis papagaios do Brasil colônia

Desde a Antiguidade, papagaios, periquitos e afins (Psittacidae) fascinaram os europeus por seu vivo colorido e uma notável capacidade de interação com seres humanos. A descoberta do Novo Mundo nada faria além de acrescentar novos elementos ao tráfico de animais exóticos há muito estabelecido pelos europeus com a África e o Oriente. Sem possuir grandes mamíferos, a América tropical participaria desse comércio com o que tinha de mais atrativo, essencialmente felinos, primatas e aves - em particular os papagaios, os quais eram embarcados em bom número. Contudo, a julgar pelos documentos do Brasil colônia, esses voláteis podiam inspirar muito pouca simpatia, pois nenhum outro animal - exceto as formigas - foi tantas vezes mencionado como praga para a agricultura. Além disso, alguns psitácidas mostravam-se tão loquazes que inspiravam a séria desconfiança de serem animais demoníacos ou possessos, pois só três classes de entidades - anjos, homens e demônios - possuíam o dom da palavra. Nos dias de hoje, vários representantes dos Psittacidae ainda constituem uma ameaça para a agricultura, enquanto os indivíduos muito faladores continuam despertando a suspeita de estarem possuídos pelo demônio. Transcendendo a mera curiosidade, essa crença exemplifica o quão intrincadas podem ser as relações do homem com o chamado “mundo natural”, revelando um universo mais amplo e multifacetado do que se poderia supor a princípio. Nesse sentido, a existência de aves capazes de falar torna essa relação ainda mais complexa e evidencia que as dificuldades de estabelecer o limite entre o animal e o humano se estendem além dos primatas e envolvem as mais inusitadas espécies zoológicas.Since ancient times, parrots and their allies (Psittacidae) have fascinated Europeans by their striking colors and notable ability to interact with human beings. The discovery of the New World added new species to the international exotic animal trade, which for many centuries had brought beasts to Europe from Africa and the Orient. Lacking large mammals, tropical America participated in this trade with its most appealing species, essentially felines, primates and birds - especially parrots - which were shipped in large numbers. It should be noted, however, that at times these birds were not well liked. In fact, according to documents from colonial Brazil, only the ants rank higher than parrots as the animals most often mentioned as agricultural pests. On the other hand, some of these birds were so chatty that people suspected them to be demonic or possessed animals, since only three classes of beings - angels, men and demons - have the ability to speak. Nowadays, several Psittacidae still constitute a threat to agriculture, and the suspicion that extremely talkative birds were demon possessed has also survived. More than a joke or a mere curiosity, this belief exemplifies how intricate man’s relationships with the “natural world” may be. In this sense, the existence of birds that are able to speak adds a further twist to these relationships, demonstrating that the problem of establishing a boundary between the animal and the human does not only involve primates, but also includes some unusual zoological species

Anales del III Congreso Internacional de Vivienda y Ciudad "Debate en torno a la nueva agenda urbana"

Acta de congresoEl III Congreso Internacional de Vivienda y Ciudad “Debates en torno a la NUEVa Agenda Urbana”, ha sido una apuesta de alto compromiso por acercar los debates centrales y urgentes que tensionan el pleno ejercicio del derecho a la ciudad. Para ello las instituciones organizadoras (INVIHAB –Instituto de Investigación de Vivienda y Hábitat y MGyDH-Maestría en Gestión y Desarrollo Habitacional-1), hemos convidado un espacio que se concretó con potencia en un debate transdisciplinario. Convocó a intelectuales de prestigio internacional, investigadores, académicos y gestores estatales, y en una metodología de innovación articuló las voces académicas con las de las organizaciones sociales y/o barriales en el Foro de las Organizaciones Sociales que tuvo su espacio propio para dar voz a quienes están trabajando en los desafíos para garantizar los derechos a la vivienda y los bienes urbanos en nuestras ciudades del Siglo XXI

Carta Pastoral, 1719, 03, 15

Com a tít. el començament del textCaplletra gravSense sign. tipNotes marginalsReclam

Carta pastoral de un señor prelado para los eclesiasticos de su diocesi

Extraido da obra: "Noticias historicas de la Santa Iglesia Cathedral de Orense / por el ilustrissimo señor D. Fr. Joan Muñoz de la Cueba, Obispo de dicha ciudad, y diocesi...". A obra completa catalogada en: CCPB000117815-6Tit. manuscrito no exemplar: "Carta Pastoral del Exmo señor D\pn\s Diego de Astorga y Cespedes, Arzobispo de la S\pta\s Yglesia de Toledo"Tit. do lomo: "Carta Pastoral"Tit. tomado da descripción da obra completaDatos da ed. tomados da descripción obra completaSign.: 2P-2G\p4\sPrelim. fechados en 172

Near UV multiphoton dissociation of organosilanes with picosecond and nanosecond laser pulses

Multiphoton dissociation undergone by the organosilanes 2-chloroethenylsilane and phenylsilane upon irradiation with laser pulses of 20 ps and 4ns duration at 290 nm has been studied through detection of their spontaneous fluorescence. Atomic Si (4s 1S0 1) emissions are reported, together with the Swan bands of C2. Additionally, SiH2 formed in a two-photon process was observed by laser-induced fluorescence techniques in the photolysis of 2-chloroethenylsilane. The results show a strong selectivity when compared to those obtained previously for far UV irradiation around 200 nm and provide insight into the nature of the photodissociation mechanisms, where the SiH2 fragment plays a central role. © 2000 Elsevier Science S.A. All rights reserved.This work was supported by the Spanish Project DGICYT (PB96-0844-C02-01). R. de Nalda thanks Ministerio de Educación y Cultura (Spain) for a scholarship.Peer Reviewe

P-T-t evolution of an Early Silurian medium-grade shear zone on the west side of the Famatinian magmatic arc, Argentina: Implications for the assembly of the Western Gondwana margin

The geodynamic evolution of the proto-Andean margin of Gondwana during the Paleozoic was characterized by repeated subduction processes associated with the docking of several terranes, including the Cuyania-Precordillera terrane and the Chilenia terrane, and the development of the calc-alkaline Famatinian continental magmatic arc. In the Sierra de La Huerta (30 degrees 56'-31 degrees 29' S and 67 degrees 17'-67 degrees 32' W), at the southwestern end of the Western Sierras Pampeanas, some mafic to ultramafic igneous bodies belonging to the Famatinian arc were affected by regional metamorphism of the medium-pressure granulite facies (7-7.5 kbar, approximate to 850 degrees C). After this regional metamorphism, local mylonitization under amphibolite facies along discrete NW-SE to NNW-SSE striking ductile shear zones occurred. A Ar-40/Ar-39 plateau age of 432 +/- 4 Ma was obtained on rather homogeneous hornblende porphyroclasts from a metagabbro mylonite. The textures and mineral chemistry of the mytonitized metagabbro allow its P-T-t evolution from magmatic crystallization to mylonitization to be constrained. Geochronological data obtained from mylonite provide evidence that orogenesis was active at least until the Early Silurian. This deformational event would have been related to uplift and decompression during the later stages of the orogenesis, probably associated with the accretion of the Precordillera terrane to the southwestern Gondwana margin