The inclusion of landmarks within navigation systems: industry requirements

Research has shown that the usability, safety and acceptability of navigation systems can be enhanced by the use of landmarks within guidance instructions. ‘Landmarks’, refer to buildings, street furniture and built aspects of the environment. The REGIONAL project aims to enable the inclusion of landmarks within future navigation systems by gaining a thorough understanding of the driver requirements for this information and the commercial enablers and barriers to their inclusion within databases, navigation software and end products. This deliverable tackles the latter issue of the requirements of industry

Human machine interface integration for driver systems

The INTEGRATE project tackled the problems that are likely to arise from the introduction of multiple driver systems each generating their own separate driver inputs and system outputs (i.e. high driver workload, impaired usability of systems and subsequent implications for safety and customer acceptance). This paper reports the results of the project: a structured human factors design approach for integrated system design. No other such design process has been documented in the publicly available literature, nor within automotive R&D departments in the UK. The content of the process is a response to the industry requirements identified within the project. Each stage of the process contributes to the main activities of: system definition, identification of potential conflicts and their likely impact, and resolution of these conflicts through good human-machine interface (HMI) design

Using landmarks to enhance navigation systems: driver requirements and industrial constraints

The task of navigating in unfamiliar road environments is a common and demanding cognitive activity for drivers. Research has long demonstrated the problems that drivers have in planning and following efficient routes to destinations. If efficient routes cannot be planned and followed, the consequences are stress, frustration and delays for the driver, potentially unsafe road behaviour (e.g. late lane changes) and inappropriate traffic management (e.g. traffic diversions through small villages)

Draft guidelines concerning E&D issues: The TELSCAN handbook of design guidelines for usability of systems by elderly and disabled drivers and travellers. Version 2

Draft guidelines concerning E&D issues: The TELSCAN handbook of design guidelines for usability of systems by elderly and disabled drivers and travellers. Version

Identifying the task characteristics that predict children's construction task performance

Construction tasks form a major part of children’s play and can be linked to achievement in maths and science. However there is a lack of understanding of construction task ability and development. Therefore, there is little foundation for the applied use of construction tasks, such as in teaching or research, as there are no apparent methods for assessing difficulty. This empirical research identifies four construction task characteristics that impact on cognition and predict construction task difficulty in children aged 7-8 and 10-11 years and adults. The results also reveal a developmental trajectory in construction ability. The research provides a method to quantify, predict and control the complexity of construction tasks for future research and to inform applied use

Thromboembolism and anticoagulant therapy during the COVID-19 pandemic: interim clinical guidance from the anticoagulation forum

Coronavirus disease 2019 (COVID-19) is a viral infection that can, in severe cases, result in cytokine storm, systemic inflammatory response and coagulopathy that is prognostic of poor outcomes. While some, but not all, laboratory findings appear similar to sepsis-associated disseminated intravascular coagulopathy (DIC), COVID-19- induced coagulopathy (CIC) appears to be more prothrombotic than hemorrhagic. It has been postulated that CIC may be an uncontrolled immunothrombotic response to COVID-19, and there is growing evidence of venous and arterial thromboembolic events in these critically ill patients. Clinicians around the globe are challenged with rapidly identifying reasonable diagnostic, monitoring and anticoagulant strategies to safely and effectively manage these patients. Thoughtful use of proven, evidence-based approaches must be carefully balanced with integration of rapidly emerging evidence and growing experience. The goal of this document is to provide guidance from the Anticoagulation Forum, a North American organization of anticoagulation providers, regarding use of anticoagulant therapies in patients with COVID-19. We discuss in-hospital and post-discharge venous thromboembolism (VTE) prevention, treatment of suspected but unconfirmed VTE, laboratory monitoring of COVID-19, associated anticoagulant therapies, and essential elements for optimized transitions of care specific to patients with COVID-19

Influence of Male to Female Ratio on Hormone Profiles and Reproductive Performance of Anestrus Postpartum Ewes Subjected to the Male Effect

Background: Complete isolation of genders allows intense estrous induction and synchronization once rams are introduced in ewe flocks at the onset of the breeding season (BS). This management practice, defined as the male effect, results from a neuroendocrine process mediated by pheromones. The male effect is a straightforward procedure to induce estrous in noncycling ewes, but conditions for its use have not been fully explored. Thus, this study aimed to evaluate hormone levels and ovarian activity of postpartum ewes in anestrus which are subjected to the male effect under different male to female ratios.Material, Methods & Results: Pospartum females were selected according to body condition score and cyclicity status. Females were kept apart from males during 30 days at a distance of 10 m. Anestrus and ovulation were determined by P4 measures on days 10, 20 and 30 after isolation from males. After P4 concentration diagnosis, anestrus ewe (n = 99) were subjected to male to ewe ratios (MFR) of 1:20 (MFR20), 1:30 (MFR30) and 1:40 (MFR40). Santa Inês rams  (n = 3) of proven fertility were used. Three females of each group were randomly subjected to blood collection for LH concentration analysis. Ovarian activity was performed by ultrasonography after estrus manifestation in six ewe of each group. Estrus events were observed twice a day during the BS of 35 days, and estrus were considered synchronized when it occured within the initial five days of the BS. Pregnancy diagnosis was performed by ultrasonography on days 35 and 60 after the last mating. All ewe were in a non-cycling condition before BS onset, based upon P4 analysis. After initiation of the BS, P4 concentrations increased for all groups. Irrespectively of male to female ratio, male effect induced LH pre-ovulatory peaks within the initial 26 to 86 h of the BS. Synchronization of estrus reached 50% for MFR20, 40% for MFR30 and 20% for MFR40 for all ewe. Moreover, overall estrus incidence was 100% (MFR20), 90% (MFR30) and 65% (MFR40) within the initial 15 days of the BS. However, incidence of ewe that had repeated estrus events was lower for MFR20 than for MFR30. Follicular growth and number of ovulations was similar between groups. Conception rates on first service was higher than that of second service for MFR20 and MFR30, although there was no difference between services for MFR40. In contrast, overall conception rates, delivery type and prolificacy were similar between groups.Discussion: P4 increased to cyclicity levels after contact between genders, demonstrating the potential of the male effect to induce estrus in non-cycling ewes. Most ewe ovulated within three days after the male effect, possibly due to elevated basal LH levels. Moreover, the LH preovulatory peak varied within groups, possibly due to greater interactions between genders, which ultimately may have led to earlier ovulation anticipation under lower MFR. Estrus parameters were similar between groups, suggesting low or negligible effects of MFR. Ovulatory follicle size and growth and the number of ovulations were similar between all groups; previous reports have suggested that this may be due to a strong effect of their genetic background. Conception rates were higher at first than second services, demonstrating the potential of male effect. In conclusion, male to female ratio affects the efficiency of the male effect to induce and synchronize estrus in ewes under postpartum anestrus, but it does not affect conception rates and prolificacy

Inventory of ATT system requirements for elderly and disabled drivers and travellers

This Inventory of ATT System Requirements for Elderly and Disabled Drivers and Travellers is the product of the TELSCAN project’s Workpackage 3: Identification and Updating of User Requirements of Elderly and Disabled Travellers. It describes the methods and tools used to identify the needs of elderly and disabled (E&D) travellers. The result of this investigation is a summary of the requirements of elderly and disabled travellers using different modes of transport, including private cars, buses/trams, metros/trains, ships and airplanes. It provides a generic user requirements specification which can guide the design of all transport telematics systems. However, it is important to stress that projects should also capture a more detailed definition of user requirements for their specific application area or system

Gleam: the GLAST Large Area Telescope Simulation Framework

This paper presents the simulation of the GLAST high energy gamma-ray telescope. The simulation package, written in C++, is based on the Geant4 toolkit, and it is integrated into a general framework used to process events. A detailed simulation of the electronic signals inside Silicon detectors has been provided and it is used for the particle tracking, which is handled by a dedicated software. A unique repository for the geometrical description of the detector has been realized using the XML language and a C++ library to access this information has been designed and implemented.Comment: 10 pages, Late