135 research outputs found

    New absolute dates as a contribution to the study of the Late Bronze Age Chronology in the Central Balkans

    Get PDF
    The paper presents three Late Bronze Age absolute dates from contexts located in the territory of western Serbia and northern Republic of Macedonia, and discusses them together with further absolute dates from the same period, which will be published shortly by one of the authors and other colleagues. On the basis of these dates the Late Bronze Age chronology is discussed together with cultural aspects of the groups representative of this period in the Central Balkans

    New contributions to the absolute chronology at the Early Eneolithic cultures in the central Balkans.

    Get PDF
    In this study we present new absolute dates for the Early Eneolithic in Serbia. Four of them confirm the recently obtained dates from that period (Bubanj-Hum I culture) but two samples (from Mokranjske stene and Bubanj) provide somewhat later dates for this period, although their stratigraphic context makes their interpretation difficult. Pottery from those sites, besides the typical examples, also shows particular stylistic and typological characteristics that resemble Galatin or SĂŁlcuĂľa IV cultures, so one can presume that the Bubanj-Hum I culture in Serbia may have lasted longer than what is generally assumed

    eSciDoc – a Scholarly Information and Communication Platform for the Max Planck Society

    Get PDF
    eSciDoc is as a joint project of the Max Planck Society and FIZ Karlsruhe, funded by the Federal Ministry of Education and Research (BMBF), with the aim to realize a next-generation platform for com-munication and publication in research organizations. The result of the entire eSciDoc project is intended to ensure open and persistent access to the research results and materials of the Max Planck Society and to integrate these materials in an emerging e-Science network, to increase the accountability of research and to improve the visibility of the Max Planck Society. At the same time, the project aims to provide effective and comprehensive access to information for Max Planck re-searchers and their work groups. Additionally, eSciDoc will support scientific collaboration and interdisciplinary research in future e-Science scenarios and optimize the exploitation of information avail-able through an interconnected global scientific knowledge space

    eSciDoc – a Scholarly Information and Communication Platform for the Max Planck Society

    Get PDF
    eSciDoc is as a joint project of the Max Planck Society and FIZ Karlsruhe, funded by the Federal Ministry of Education and Research (BMBF), with the aim to realize a next-generation platform for com-munication and publication in research organizations. The result of the entire eSciDoc project is intended to ensure open and persistent access to the research results and materials of the Max Planck Society and to integrate these materials in an emerging e-Science network, to increase the accountability of research and to improve the visibility of the Max Planck Society. At the same time, the project aims to provide effective and comprehensive access to information for Max Planck re-searchers and their work groups. Additionally, eSciDoc will support scientific collaboration and interdisciplinary research in future e-Science scenarios and optimize the exploitation of information avail-able through an interconnected global scientific knowledge space

    In Vitro Induction Of Adenovirus Specific T-cells In Response To 15-mer Peptides In Umbilical Cord Blood

    Get PDF

    Digital Scrapbook – can we enable interlinked and recursive knowledge equilibrium?

    Get PDF
    We investigate possible tools and approaches to develop a Digital Scrapbook, a virtual research environment inspired by the recursive nature of research for scholars where they can combine web and own resources into a new scholarly edition readily enabled for Open Access. Web resources are interlinked in the digital scrapbook by content capture and detail selection, rather than sole bookmark or link to resource URL, along with necessary accompanying metadata. We analyse several open source and commercial tools, with special focus on a Scrapbook-X Firefox Add-On, in order to match to desired Digital Scrapbook features. We further address the wider requirement context for development of such Digital Scrapbook environment, discussing both technical and user experience dimensions. We conclude with a recommendation on how to approach the development and operation of a Digital Scrapbook environment

    Large-eddy simulation of a two-layer boundary-layer cloud system from the Arctic Ocean 2018 expedition

    Get PDF
    Climate change is particularly noticeable in the Arctic. The most common type of cloud at these latitudes is mixed-phase stratocumulus. These clouds occur frequently and persistently during all seasons and play a critical role in the Arctic energy budget. Previous observations in the central (north of 80&deg; N) Arctic have shown a high occurrence of prolonged periods of a shallow, single-layer mixed-phase stratocumulus at the top of the boundary layer (BL; altitudes ~300 to 400 m). However, recent observations from the summer of 2018 instead showed a prevalence of a two-layer boundary-layer cloud system. Here we use large-eddy simulation to examine the maintenance of one of the cloud systems observed in the summer of 2018 as well as the sensitivity of the cloud layers to different micro- and macro-scale parameters. We find that the model generally reproduces the observed thermodynamic structure well, with two near-neutrally stratified layers in the BL caused by a low cloud (located within the first few hundred meters) capped by a lower temperature inversion, and an upper cloud layer (based around one km or slightly higher) capped by the main temperature inversion of the BL. The investigated cloud structure is persistent unless there are low aerosol number concentrations (&le; 5 cm-3), which cause the upper cloud layer to dissipate, or high large-scale wind speeds (greater than or equal 8.5 m s-1), which erode the lower inversion and the related cloud layer. These types of changes in cloud structure lead to a substantial reduction of the net longwave radiation at the surface due to a lower emissivity or higher altitude of the remaining cloud layer. The findings highlight the importance of better understanding and representing aerosol sources and sinks over the central Arctic Ocean. Furthermore, they underline the significance of meteorological parameters, such as the large-scale wind speed, for maintaining the two-layer boundary-layer cloud structure encountered in the lower atmosphere of the central Arctic.</p

    Enclosing the Neolithic World: A VinÄŤa Culture Enclosed and Fortified Settlement in the Balkans

    Get PDF
    Interpretations of prehistoric enclosures worldwide have varied from those that see the primary role of enclosures as defensive features to others that explore the symbolic, ritual, social, and ideological dimensions of separating space into an inside, an outside, and an in-between. Such evidence and interpretative accounts are inevitably linked to wider anthropological discussions on modes of social interaction and reproduction in the past, whether altruistic or predatory, and evolutionary narratives regarding changes in the level of intergroup violence over the course of human history. Growing evidence indicates that many Neolithic settlements in Europe were enclosed by a complex system of ditches, ramparts, and palisades. We present a case study from the central Balkans at the Neolithic Vinča culture site of Oreškovica-Selište in Serbia, dated to the last centuries of the sixth millennium BC, where recent geophysical surveys, stratigraphic excavation, and accelerator mass spectrometry dating document the existence of an early enclosed settlement with multiple enclosure features. We interpret these features as defensive and discuss the social dynamics that led to the founding and abandonment of this short-lived occupation in the context of other contemporaneous settlements in the Balkans

    Ischemia-Reperfusion Injury and Pregnancy Initiate Time-Dependent and Robust Signs of Up-Regulation of Cardiac Progenitor Cells

    Get PDF
    To explore how cardiac regeneration and cell turnover adapts to disease, different forms of stress were studied for their effects on the cardiac progenitor cell markers c-Kit and Isl1, the early cardiomyocyte marker Nkx2.5, and mast cells. Adult female rats were examined during pregnancy, after myocardial infarction and ischemia-reperfusion injury with/out insulin like growth factor-1(IGF-1) and hepatocyte growth factor (HGF). Different cardiac sub-domains were analyzed at one and two weeks post-intervention, both at the mRNA and protein levels. While pregnancy and myocardial infarction up-regulated Nkx2.5 and c-Kit (adjusted for mast cell activation), ischemia-reperfusion injury induced the strongest up-regulation which occurred globally throughout the entire heart and not just around the site of injury. This response seems to be partly mediated by increased endogenous production of IGF-1 and HGF. Contrary to c-Kit, Isl1 was not up-regulated by pregnancy or myocardial infarction while ischemia-reperfusion injury induced not a global but a focal up-regulation in the outflow tract and also in the peri-ischemic region, correlating with the up-regulation of endogenous IGF-1. The addition of IGF-1 and HGF did boost the endogenous expression of IGF and HGF correlating to focal up-regulation of Isl1. c-Kit expression was not further influenced by the exogenous growth factors. This indicates that there is a spatial mismatch between on one hand c-Kit and Nkx2.5 expression and on the other hand Isl1 expression. In conclusion, ischemia-reperfusion injury was the strongest stimulus with both global and focal cardiomyocyte progenitor cell marker up-regulations, correlating to the endogenous up-regulation of the growth factors IGF-1 and HGF. Also pregnancy induced a general up-regulation of c-Kit and early Nkx2.5+ cardiomyocytes throughout the heart. Utilization of these pathways could provide new strategies for the treatment of cardiac disease
    • …
    corecore