123 research outputs found
Numerical simulations of the Warm-Hot Intergalactic Medium
In this paper we review the current predictions of numerical simulations for
the origin and observability of the warm hot intergalactic medium (WHIM), the
diffuse gas that contains up to 50 per cent of the baryons at z~0. During
structure formation, gravitational accretion shocks emerging from collapsing
regions gradually heat the intergalactic medium (IGM) to temperatures in the
range T~10^5-10^7 K. The WHIM is predicted to radiate most of its energy in the
ultraviolet (UV) and X-ray bands and to contribute a significant fraction of
the soft X-ray background emission. While O VI and C IV absorption systems
arising in the cooler fraction of the WHIM with T~10^5-10^5.5 K are seen in
FUSE and HST observations, models agree that current X-ray telescopes such as
Chandra and XMM-Newton do not have enough sensitivity to detect the hotter
WHIM. However, future missions such as Constellation-X and XEUS might be able
to detect both emission lines and absorption systems from highly ionised atoms
such as O VII, O VIII and Fe XVII.Comment: 18 pages, 5 figures, accepted for publication in Space Science
Reviews, special issue "Clusters of galaxies: beyond the thermal view",
Editor J.S. Kaastra, Chapter 14; work done by an international team at the
International Space Science Institute (ISSI), Bern, organised by J.S.
Kaastra, A.M. Bykov, S. Schindler & J.A.M. Bleeke
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Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?
This work was supported by National Institute of Biomedical Imaging and Bioengineering Grant No. U54EB020403 (to the ENIGMA consortium)
Lasers and optics: Looking towards third generation gravitational wave detectors
Third generation terrestrial interferometric gravitational wave detectors will likely require significant advances in laser and optical technologies to reduce two of the main limiting noise sources: thermal noise due to mirror coatings and quantum noise arising from a combination of shot noise and radiation pressure noise. Increases in laser power and possible changes of the operational wavelength require new high power laser sources and new electro-optic modulators and Faraday isolators. Squeezed light can be used to further reduce the quantum noise while nano-structured optical components can be used to reduce or eliminate mirror coating thermal noise as well as to implement all-reflective interferometer configurations to avoid thermal effects in mirror substrates. This paper is intended to give an overview on the current state-of-the-art and future trends in these areas of ongoing research and development.NSF/PHY0555453NSF/PHY0757968NSF/PHY0653582DFG/SFB/407DFG/SFB/TR7DFG/EXC/QUES
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Operational characteristics and analysis of the immersed-Bz diode on RITS-3.
The immersed-B{sub z} diode is being developed as a high-brightness, flash x-ray radiography source. This diode is a foil-less electron-beam diode with a long, thin, needle-like cathode inserted into the bore of a solenoid. The solenoidal magnetic field guides the electron beam emitted from the cathode to the anode while maintaining a small beam radius. The electron beam strikes a thin, high-atomic-number anode and produces bremsstrahlung. We report on an extensive series of experiments where an immersed-B{sub z} diode was fielded on the RITS-3 pulsed power accelerator, a 3-cell inductive voltage generator that produced peak voltages between 4 and 5 MV, {approx}140 kA of total current, and power pulse widths of {approx}50 ns. The diode is a high impedance device that, for these parameters, nominally conducts {approx}30 kA of electron beam current. Diode operating characteristics are presented and two broadly characterized operating regimes are identified: a nominal operating regime where the total diode current is characterized as classically bipolar and an anomalous impedance collapse regime where the total diode current is in excess of the bipolar limit and up to the full accelerator current. The operating regimes are approximately separated by cathode diameters greater than {approx}3 mm for the nominal regime and less than {approx} 3 mm for the anomalous impedance collapse regime. This report represents a compilation of data taken on RITS-3. Results from key parameter variations are presented in the main body of the report and include cathode diameter, anode-cathode gap, and anode material. Results from supporting parameter variations are presented in the appendices and include magnetic field strength, prepulse, pressure and accelerator variations
Cosmology with clusters of galaxies
In this Chapter I review the role that galaxy clusters play as tools to
constrain cosmological parameters. I will concentrate mostly on the application
of the mass function of galaxy clusters, while other methods, such as that
based on the baryon fraction, are covered by other Chapters of the book. Since
most of the cosmological applications of galaxy clusters rely on precise
measurements of their masses, a substantial part of my Lectures concentrates on
the different methods that have been applied so far to weight galaxy clusters.
I provide in Section 2 a short introduction to the basics of cosmic structure
formation. In Section 3 I describe the Press--Schechter (PS) formalism to
derive the cosmological mass function, then discussing extensions of the PS
approach and the most recent calibrations from N--body simulations. In Section
4 I review the methods to build samples of galaxy clusters at different
wavelengths. Section 5 is devoted to the discussion of different methods to
derive cluster masses. In Section 6 I describe the cosmological constraints,
which have been obtained so far by tracing the cluster mass function with a
variety of methods. Finally, I describe in Section 7 the future perspectives
for cosmology with galaxy clusters and the challenges for clusters to keep
playing an important role in the era of precision cosmology.Comment: 49 pages, 19 figures, Lectures for 2005 Guillermo Haro Summer School
on Clusters, to appear in "Lecture notes in Physics" (Springer
Clusters of galaxies: setting the stage
Clusters of galaxies are self-gravitating systems of mass ~10^14-10^15 Msun.
They consist of dark matter (~80 %), hot diffuse intracluster plasma (< 20 %)
and a small fraction of stars, dust, and cold gas, mostly locked in galaxies.
In most clusters, scaling relations between their properties testify that the
cluster components are in approximate dynamical equilibrium within the cluster
gravitational potential well. However, spatially inhomogeneous thermal and
non-thermal emission of the intracluster medium (ICM), observed in some
clusters in the X-ray and radio bands, and the kinematic and morphological
segregation of galaxies are a signature of non-gravitational processes, ongoing
cluster merging and interactions. In the current bottom-up scenario for the
formation of cosmic structure, clusters are the most massive nodes of the
filamentary large-scale structure of the cosmic web and form by anisotropic and
episodic accretion of mass. In this model of the universe dominated by cold
dark matter, at the present time most baryons are expected to be in a diffuse
component rather than in stars and galaxies; moreover, ~50 % of this diffuse
component has temperature ~0.01-1 keV and permeates the filamentary
distribution of the dark matter. The temperature of this Warm-Hot Intergalactic
Medium (WHIM) increases with the local density and its search in the outer
regions of clusters and lower density regions has been the quest of much recent
observational effort. Over the last thirty years, an impressive coherent
picture of the formation and evolution of cosmic structures has emerged from
the intense interplay between observations, theory and numerical experiments.
Future efforts will continue to test whether this picture keeps being valid,
needs corrections or suffers dramatic failures in its predictive power.Comment: 20 pages, 8 figures, accepted for publication in Space Science
Reviews, special issue "Clusters of galaxies: beyond the thermal view",
Editor J.S. Kaastra, Chapter 2; work done by an international team at the
International Space Science Institute (ISSI), Bern, organised by J.S.
Kaastra, A.M. Bykov, S. Schindler & J.A.M. Bleeke
Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the enhancing neuro Imaging genetics through meta analysis (ENIGMA) Consortium
BACKGROUND: The profile of cortical neuroanatomical abnormalities in schizophrenia is not fully understood, despite hundreds of published structural brain imaging studies. This study presents the first meta-analysis of cortical thickness and surface area abnormalities in schizophrenia conducted by the ENIGMA (Enhancing Neuro Imaging Genetics through Meta Analysis) Schizophrenia Working Group.
METHODS: The study included data from 4474 individuals with schizophrenia (mean age, 32.3 years; range, 11-78 years; 66% male) and 5098 healthy volunteers (mean age, 32.8 years; range, 10-87 years; 53% male) assessed with standardized methods at 39 centers worldwide.
RESULTS: Compared with healthy volunteers, individuals with schizophrenia have widespread thinner cortex (left/right hemisphere: Cohen's d = -0.530/-0.516) and smaller surface area (left/right hemisphere: Cohen's d = -0.251/-0.254), with the largest effect sizes for both in frontal and temporal lobe regions. Regional group differences in cortical thickness remained significant when statistically controlling for global cortical thickness, suggesting regional specificity. In contrast, effects for cortical surface area appear global. Case-control, negative, cortical thickness effect sizes were two to three times larger in individuals receiving antipsychotic medication relative to unmedicated individuals. Negative correlations between age and bilateral temporal pole thickness were stronger in individuals with schizophrenia than in healthy volunteers. Regional cortical thickness showed significant negative correlations with normalized medication dose, symptom severity, and duration of illness and positive correlations with age at onset.
CONCLUSIONS: The findings indicate that the ENIGMA meta-analysis approach can achieve robust findings in clinical neuroscience studies; also, medication effects should be taken into account in future genetic association studies of cortical thickness in schizophrenia
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