A phenomenological theory giving the full statistics of the position of fluctuating pulled fronts

We propose a phenomenological description for the effect of a weak noise on the position of a front described by the Fisher-Kolmogorov-Petrovsky-Piscounov equation or any other travelling wave equation in the same class. Our scenario is based on four hypotheses on the relevant mechanism for the diffusion of the front. Our parameter-free analytical predictions for the velocity of the front, its diffusion constant and higher cumulants of its position agree with numerical simulations.Comment: 10 pages, 3 figure

Genealogies of rapidly adapting populations

The genetic diversity of a species is shaped by its recent evolutionary history and can be used to infer demographic events or selective sweeps. Most inference methods are based on the null hypothesis that natural selection is a weak or infrequent evolutionary force. However, many species, particularly pathogens, are under continuous pressure to adapt in response to changing environments. A statistical framework for inference from diversity data of such populations is currently lacking. Toward this goal, we explore the properties of genealogies in a model of continual adaptation in asexual populations. We show that lineages trace back to a small pool of highly fit ancestors, in which almost simultaneous coalescence of more than two lineages frequently occurs. While such multiple mergers are unlikely under the neutral coalescent, they create a unique genetic footprint in adapting populations. The site frequency spectrum of derived neutral alleles, for example, is non-monotonic and has a peak at high frequencies, whereas Tajima's D becomes more and more negative with increasing sample size. Since multiple merger coalescents emerge in many models of rapid adaptation, we argue that they should be considered as a null-model for adapting populations.Comment: to appear in PNA

An Intrisic Topology for Orthomodular Lattices

We present a general way to define a topology on orthomodular lattices. We show that in the case of a Hilbert lattice, this topology is equivalent to that induced by the metrics of the corresponding Hilbert space. Moreover, we show that in the case of a boolean algebra, the obtained topology is the discrete one. Thus, our construction provides a general tool for studying orthomodular lattices but also a way to distinguish classical and quantum logics.Comment: Under submission to the International Journal of Theoretical Physic

An exactly soluble noisy traveling wave equation appearing in the problem of directed polymers in a random medium

We calculate exactly the velocity and diffusion constant of a microscopic stochastic model of $N$ evolving particles which can be described by a noisy traveling wave equation with a noise of order $N^{-1/2}$. Our model can be viewed as the infinite range limit of a directed polymer in random medium with $N$ sites in the transverse direction. Despite some peculiarities of the traveling wave equations in the absence of noise, our exact solution allows us to test the validity of a simple cutoff approximation and to show that, in the weak noise limit, the position of the front can be completely described by the effect of the noise on the first particle.Comment: 5 page

To grate a liquid into tiny droplets by its impact on a hydrophobic micro-grid

We report on experiments of drop impacting a hydrophobic micro-grid, of typical spacing a few tens of $\mu$m. Above a threshold in impact speed, liquid emerges to the other side, forming micro-droplets of size about that of the grid holes. We propose a method to produce either a mono-disperse spray or a single tiny droplet of volume as small as a few picoliters corresponding to a volume division of the liquid drop by a factor of up to 10$^5$. We also discuss the discrepancy of the measured thresholds with that predicted by a balance between inertia and capillarity.Comment: 3 pages, 5 figures, Accepted for publication in Applied Physics Letter

Sensible and latent heat flux from radiometric surface temperatures at the regional scale: methodology and validation

The CarboEurope Regional Experiment Strategy (CERES) was designed to develop and test a range of methodologies to assess regional surface energy and mass exchange of a large study area in the south-western part of France. This paper describes a methodology to estimate sensible and latent heat fluxes on the basis of net radiation, surface radiometric temperature measurements and information obtained from available products derived from the Meteosat Second Generation (MSG) geostationary meteorological satellite, weather stations and ground-based eddy covariance towers. It is based on a simplified bulk formulation of sensible heat flux that considers the degree of coupling between the vegetation and the atmosphere and estimates latent heat as the residual term of net radiation. Estimates of regional energy fluxes obtained in this way are validated at the regional scale by means of a comparison with direct flux measurements made by airborne eddy-covariance. The results show an overall good matching between airborne fluxes and estimates of sensible and latent heat flux obtained from radiometric surface temperatures that holds for different weather conditions and different land use types. The overall applicability of the proposed methodology to regional studies is discusse

Biases in the determination of dynamical parameters of star clusters: today and in the Gaia era

The structural and dynamical properties of star clusters are generally derived by means of the comparison between steady-state analytic models and the available observables. With the aim of studying the biases of this approach, we fitted different analytic models to simulated observations obtained from a suite of direct N-body simulations of star clusters in different stages of their evolution and under different levels of tidal stress to derive mass, mass function and degree of anisotropy. We find that masses can be under/over-estimated up to 50% depending on the degree of relaxation reached by the cluster, the available range of observed masses and distances of radial velocity measures from the cluster center and the strength of the tidal field. The mass function slope appears to be better constrainable and less sensitive to model inadequacies unless strongly dynamically evolved clusters and a non-optimal location of the measured luminosity function are considered. The degree and the characteristics of the anisotropy developed in the N-body simulations are not adequately reproduced by popular analytic models and can be detected only if accurate proper motions are available. We show how to reduce the uncertainties in the mass, mass-function and anisotropy estimation and provide predictions for the improvements expected when Gaia proper motions will be available in the near future.Comment: 14 pages, 8 figures, accepted for publication by MNRA

Synthesis studies to single stereoisomers of the vicinal trifluoroalkane motif

This thesis focuses on the construction of individual isomers of the R-CHF-CHF-CHF-R’ motif. The multi-vicinal fluorine motif is new in organic chemistry and therefore stereoselective methods giving rapid access to these motifs and with flexibility need to be explored. The research in the thesis succeeded in the preparation of (2S,3R,4S)-314 and (2S,3S,4R)-328. In Chapter 1, an overview of the impact of fluorine in organic molecules is given. Recent developments in asymmetric electrophilic and nucleophilic fluorination are described, as well as the preparation of multivicinal fluoroalkane motifs. Aldol reactions of either (R)- or (S)-N-(α-fluoropropyl)-2-oxazolidinones, mediated by TiCl 4 are reported in Chapter 2. Such aldol reactions gave rise to identical α-fluoro-β-hydroxy- aldol products with high diastereoselectivities (95% dr). After removal from the auxiliary α- fluoro-β-hydroxy- products were converted to the corresponding α,β-difluoro products. The synthesis of non symmetric vicinal trifluoro motifs (2S,3R,4S)-314 and (2S,3S,4R)-328 is described in Chapter 3. They were prepared by direct fluorination in three steps of the corresponding (2R,3R,4R)-erythro and (2R,3S,4S)-threo enantio-enriched epoxy-alcohols. The two erythro and threo epoxy-alcohol isomers behave very differently during the first fluorination step and then an attempt to study and rationalise this difference in behaviour is made

Emergence of pulled fronts in fermionic microscopic particle models

We study the emergence and dynamics of pulled fronts described by the Fisher-Kolmogorov-Petrovsky-Piscounov (FKPP) equation in the microscopic reaction-diffusion process A + A A$ on the lattice when only a particle is allowed per site. To this end we identify the parameter that controls the strength of internal fluctuations in this model, namely, the number of particles per correlated volume. When internal fluctuations are suppressed, we explictly see the matching between the deterministic FKPP description and the microscopic particle model.Comment: 4 pages, 4 figures. Accepted for publication in Phys. Rev. E as a Rapid Communicatio

Data sources for rescuing the rich heritage of Mediterranean historical surface climate data

10.1002/gdj3.4Availability of long-term and high-quality instrumental climate records is still insufficient and the rich heritage of meteorological surface observations is largely underexploited in many parts of the world. This is particularly striking over the Greater Mediterranean region (GMR), where meteorological observations have been taken since the 18th century at some locations. The lack of high quality and long series here is despite this region being regarded as a climate change hot spot. This article mainly assesses relevant sources containing Mediterranean historical climate data and metadata either from online repositories worldwide or physical archives, with the emphasis here on the rich holdings kept at French archives. A particular case study is the data rescue (DARE) program undertaken by the Algerian National Meteorological Service, as well as some of the past and ongoing projects and initiatives aimed at enhancing climate data availability and accessibility over the GMR. Our findings point to the high potential for undertaking DARE activities over the GMR and the need for bringing longer and higher quality climate time series to support a diverse number of scientific and technical assessments and policies