Contribució de Ramon de Bolòs (1852-1914) a la briologia catalana

List of the Briophytic species from the R. de Bolòs Herbarium. Entodon cladorrhizans (Hedw.) C. Muell. and Tayloria froelichiana (Hedw.) Mitt. can be considered as new for Catalonia

Estudio monográfico del orden "Polytrichales" en España. (Ensayo para una flora briológica española)

Cada vez es más patente la necesidad de una flora briológica española. A tal fin se propone en esta comunicación el estudio de la familia Polytrichaceae en España, única que constituye el Orden Polytrichales, como base, esquema o ejemplo para realizar dicha flora.The need for a Spanish bryologycal flora is becoming increasingly apparent. With this need in mind, this work proposes the study of the family Polytrichaceae in Spain, the only one which constitutes the Order Polytrichales, as a basis, scheme or example for the realisation of such a flora

Els Briòfits de les basses de l?Albera, Alt Empordà

Hem estudiat unes basses i unes depressions temporalment inundades en les quals, en evaporar- se l'aigua, sobre el sòl emergit, s'hi observa una elevada diversitat i abundància de briòfits. Per a la distribució dels briòfits hem establert tres zones concèntriques en relació amb el grau d'humitat. En la més externa i excepcionalment inundada, hi destaquen les hepàtiques Riccia gougetiana i Fossombronia maritima i diverses antocerotes; en la zona emergida, Pseudephemerum nitidum, Archidium alternifolium i un nombre elevat d'espècies del gènere Riccia, com R. macro-carpa i R. warnstorfii. En algunes basses on el període d'inundació és llarg, hi hem observat molses pleurocàrpiques, com Amblystegium riparium i Drepanocladus aduncus.Hemos estudiado diversas charcas y depresiones inundadas temporalmente en las que al evaporarse el agua, y sobre el suelo emergente, se observa una elevada diversidad y abundancia de briófitos. Para la distribución de los briófitos hemos establecido tres zonas concéntricas en relación con el grado de humedad. En la más externa y excepcionalmente inundada destacamos las hepáticas Riccia gougetiana y Fossombronia maritima y diversas antocerotas; en la zona emergida Pseudephemerum nitidum, Archidium alternifolium y un elevado numero de especies del género Riccia como R. macrocarpa y R. warnstorfii. En algunas charcas donde el periodo de inundación es prolongado hemos observado musgos pleurocárpicos como Amblystegium riparium y Drepanocladus aduncus.We have studied some depressions and areas temporarily flooded where after the water evaporates, a high diversity and abundance of bryophyta can be observed on the emerged soil. For the distribution of these bryophytes we have established three concentric zones according to their humidity level. At the most external one, which is seldom flooded, the hepatics Riccia gougetiana and Fossombronia maritima were found, as well as various Anthocerotae. At the emerged zone Pseudephemerum nitidum, Archidium alternifolium and a high number of Riccia species, such as R. macrocarpa and R. warnstorfii could be found. In some depressions with a long flooding period, we observed pleurocarpous mosses such as Amblystegium riparium and Drepanocladus aduncus

Briòfits de l'Alt Empordà

En aquest treball presentem el catàleg dels Briòfits coneguts fins ara a l'Alt Empordà. Citem 181 espècies de molses i 59 d'hepàtiques. La major part de les dades es deuen a la Dra. Creu Casas que va estudiar molt intensament é1 Cap de Creus fent troballes molt notables: Entosthodon durieui var. mustaphae, molsa nordafricana desconeguda a Europa, Exormotheca pustulosa, hepàtica citada a Monchique (Portugal), i la varietat nova de l'espècie sudafricana Oedipodiella australis var. catalaunica. Més tard, va recol·lectar Leucobryum juniperoideum a Sant Llorenç de la Muga, espècie considerada oceànica. Es troba amb altres espécies de tendència atlàntica com Harpalejeunea ovata, Hedwigia integrifolia i Campylopus flexuosus. Cal destacar també la darrera recol·lecció al Cap Norfeu de Bryum gemmiluscens, primera cita a la Península

Preoperative oral antibiotic prophylaxis reduces Pseudomonas aeruginosa surgical site infections after elective colorectal surgery: a multicenter prospective cohort study

BACKGROUND: Healthcare-associated infections caused by Pseudomonas aeruginosa are associated with poor outcomes. However, the role of P. aeruginosa in surgical site infections after colorectal surgery has not been evaluated. The aim of this study was to determine the predictive factors and outcomes of surgical site infections caused by P. aeruginosa after colorectal surgery, with special emphasis on the role of preoperative oral antibiotic prophylaxis. METHODS: We conducted an observational, multicenter, prospective cohort study of all patients undergoing elective colorectal surgery at 10 Spanish hospitals (2011-2014). A logistic regression model was used to identify predictive factors for P. aeruginosa surgical site infections. RESULTS: Out of 3701 patients, 669 (18.1%) developed surgical site infections, and 62 (9.3%) of these were due to P. aeruginosa. The following factors were found to differentiate between P. aeruginosa surgical site infections and those caused by other microorganisms: American Society of Anesthesiologists' score III-IV (67.7% vs 45.5%, p = 0.001, odds ratio (OR) 2.5, 95% confidence interval (95% CI) 1.44-4.39), National Nosocomial Infections Surveillance risk index 1-2 (74.2% vs 44.2%, p < 0.001, OR 3.6, 95% CI 2.01-6.56), duration of surgery ≥75thpercentile (61.3% vs 41.4%, p = 0.003, OR 2.2, 95% CI 1.31-3.83) and oral antibiotic prophylaxis (17.7% vs 33.6%, p = 0.01, OR 0.4, 95% CI 0.21-0.83). Patients with P. aeruginosa surgical site infections were administered antibiotic treatment for a longer duration (median 17 days [interquartile range (IQR) 10-24] vs 13d [IQR 8-20], p = 0.015, OR 1.1, 95% CI 1.00-1.12), had a higher treatment failure rate (30.6% vs 20.8%, p = 0.07, OR 1.7, 95% CI 0.96-2.99), and longer hospitalization (median 22 days [IQR 15-42] vs 19d [IQR 12-28], p = 0.02, OR 1.1, 95% CI 1.00-1.17) than those with surgical site infections due to other microorganisms. Independent predictive factors associated with P. aeruginosa surgical site infections were the National Nosocomial Infections Surveillance risk index 1-2 (OR 2.3, 95% CI 1.03-5.40) and the use of oral antibiotic prophylaxis (OR 0.4, 95% CI 0.23-0.90). CONCLUSIONS: We observed that surgical site infections due to P. aeruginosa are associated with a higher National Nosocomial Infections Surveillance risk index, poor outcomes, and lack of preoperative oral antibiotic prophylaxis. These findings can aid in establishing specific preventive measures and appropriate empirical antibiotic treatment

First-line treatment in lymphomatoid papulosis: a retrospective multicentre study

Background: Data regarding response to treatment in lymphomatoid papulosis (LyP) are scarce. Aim: To assess the daily clinical practice approach to LyP and the response to first-line treatments. Methods: This was a retrospective study enrolling 252 patients with LyP. Results: Topical steroids, methotrexate and phototherapy were the most common first-line treatments, prescribed for 35%, 20% and 14% of the patients, respectively. Complete response (CR) was achieved in 48% of treated patients. Eczematous lesions significantly increased relative risk (RR) of not achieving CR (RR = 1.76; 95% CI 1.16-2.11). Overall median time to CR was 10 months (95% CI 6-13 months), and 78% of complete responders showed cutaneous relapse; both results were similar for all treatment groups (P > 0.05). Overall estimated median disease-free survival (DFS) was 11 months (95% CI 9-13 months) but DFS for patients treated with phototherapy was 23 months (95% CI 10-36 months; P < 0.03). Having the Type A LyP variant (RR = 2.04; 95% CI 0.96-4.30) and receiving a first-line treatment other than phototherapy (RR = 5.33; 95% CI 0.84-33.89) were significantly associated with cutaneous early relapse. Of the 252 patients, 31 (13%) had associated mycosis fungoides unrelated to therapeutic approach, type of LyP or T-cell receptor clonality. Conclusions: Current epidemiological, clinical and pathological data support previous results. Topical steroids, phototherapy and methotrexate are the most frequently prescribed first-line treatments. Although CR and cutaneous relapse rates do not differ between them, phototherapy achieves a longer DFS. Presence of Type A LyP and use of topical steroid or methotrexate were associated with an increased risk of early relapse

Trends in the epidemiology of catheter-related bloodstream infections; towards a paradigm shift, Spain, 2007 to 2019

Altres ajuts: Departament de Salut. Generalitat de Catalunya ("Pla estratègic de recerca i innovació en salut (PERIS) 2019-2021"); Ministerio de Asuntos Económicos y Transformación Digital; Red Española de Investigación en Patología Infecciosa (REIPI).Background: Catheter-related bloodstream infections (CRBSI) are frequent healthcare-associated infections and an important cause of death. Aim: To analyse changes in CRBSI epidemiology observed by the Infection Control Catalan Programme (VINCat). Methods: A cohort study including all hospital-acquired CRBSI episodes diagnosed at 55 hospitals (2007-2019) in Catalonia, Spain, was prospectively conducted. CRBSI incidence rates were adjusted per 1,000patientdays. To assess the CRBSI rate trend per year, negative binomial models were used, with the number of events as the dependent variable, and the year as the main independent variable. From each model, the annual rate of CRBSI diagnosed per 1,000patientdays and the incidence rate ratio (IRR) with its 95% confidence intervals (CI) were reported. Results: During the study, 9,290 CRBSI episodes were diagnosed (mean annual incidence rate:0.20episodes/1,000patientdays). Patients' median age was 64.1years; 36.6% (3,403/9,290) were female. In total, 73.7% (n=6,845) of CRBSI occurred in non-intensive care unit (ICU) wards, 62.7% (n=5,822) were related to central venous catheter (CVC), 24.1% (n=2,236) to peripheral venous catheters (PVC) and 13.3% (n=1,232) to peripherally-inserted central venous catheters (PICVC). Incidence rate fell over the study period (IRR:0.94;95%CI:0.93-0.96), especially in the ICU (IRR:0.88;95%CI:0.87-0.89). As a whole, while episodes of CVC CRBSI fell significantly (IRR:0.88;95%CI:0.87-0.91), peripherally-inserted catheter CRBSI (PVC and PICVC) rose, especially in medical wards (IRR PICVC:1.08;95%CI:1.05-1.11; IRR PVC: 1.03; 95% 1.00-1.05). Conclusions: Over the study, CRBSIs associated with CVC and diagnosed in ICUs decreased while episodes in conventional wards involving peripherally-inserted catheters increased. Hospitals should implement preventive measures in conventional wards