The Common Shrew (Sorex araneus): A neglected host of tick-borne infections?

Although the importance of rodents as reservoirs for a number of tick-borne infections is well established, comparatively little is known about the potential role of shrews, despite them occupying similar habitats. To address this, blood and tick samples were collected from common shrews (Sorex araneus) and field voles (Microtus agrestis), a known reservoir of various tick-borne infections, from sites located within a plantation forest in northern England over a 2-year period. Of 647 blood samples collected from shrews, 121 (18.7%) showed evidence of infection with Anaplasma phagocytophilum and 196 (30.3%) with Babesia microti. By comparison, of 1505 blood samples from field voles, 96 (6.4%) were positive for A. phagocytophilum and 458 (30.4%) for Ba. microti. Both species were infested with the ticks Ixodes ricinus and Ixodes trianguliceps, although they had different burdens: on average, shrews carried almost six times as many I. trianguliceps larvae, more than twice as many I. ricinus larvae, and over twice as many nymphs (both tick species combined). The finding that the nymphs collected from shrews were almost exclusively I. trianguliceps highlights that this species is the key vector of these infections in this small mammal community. These findings suggest that common shrews are a reservoir of tick-borne infections and that the role of shrews in the ecology and epidemiology of tick-borne infections elsewhere needs to be comprehensively investigated

Prevalence and determinants of osteoporosis in patients with type 1 and type 2 diabetes mellitus

Background: Increased risk of osteoporosis and its clinical significance in patients with diabetes is controversial. We analyze osteoporosis prevalence and determinants of bone mineral density (BMD) in patients with type 1 and 2 diabetes. Methods: Three hundred and ninety-eight consecutive diabetic patients from a single outpatient clinic received a standardized questionnaire on osteoporosis risk factors, and were evaluated for diabetes-related complications, HbA1c levels, and lumbar spine (LS) and femoral neck (FN) BMD. Of these, 139 (71 men, 68 women) type 1 and 243 (115 men, 128 women) type 2 diabetes patients were included in the study. BMD (T-scores and values adjusted for age, BMI and duration of disease) was compared between patient groups and between patients with type 2 diabetes and population-based controls (255 men, 249 women). Results: For both genders, adjusted BMD was not different between the type 1 and type 2 diabetes groups but was higher in the type 2 group compared with controls (p

Review of land flow accounting methods and recommendations for further development

Robust land footprint indicators can potentially extend the consumption-based resource use indicator of the German sustainability strategy, which focuses on abiotic resources including fossil fuels, metals, and construction and industrial minerals and decidedly excludes biotic resources. Various approaches exist for quantifying the land embodied in international trade flows and consumption, i.e. the land footprint. These can be classified into a) environmental-economic accounting approaches, applying input-output analysis and tracking supply chains in monetary values, b) physical accounting approaches, using an accounting framework based on data for production, trade and utilization of agricultural and forestry commodities and tracking supply chains in physical units, and c) hybrid accounting, combining elements from both environmental-economic and physical accounting. The results of recent studies vary widely, indicating a lack of robustness and thus hampering their application in policy making. This report provides an in-depth review of the current state of the art in measuring land footprints. We identify differences in available accounting methods and indicate their shortcomings, which are mainly attributable to the product and supply chain coverage and detail, and biases introduced by the use of monetary flows as a proxy for actual physical flows. We offer options and give clear recommendations for the further development of actual and virtual global biomass and land flow accounting methods, particularly highlighting the advantages of hybrid accounting approaches as a framework for the robust and transparent assessment of land footprints associated with global biomass flows

Quantifying the land footprint of Germany and the EU using a hybrid accounting model

Footprint analysis reveals the appropriation of land resources from a consumer’s perspective. We here present a novel hybrid land-flow accounting method for the calculation of land footprints, employing a globally consistent top-down approach and combining physical with environmental economic accounting. Physical accounting tracks food products from ‘field to plate’ and non-food from ‘field to industrial use’ using the large harmonized FAO data to track biomass flows and related land use in physical volumes (tons of biomass). Environmental-economic accounting is used to further track non-food commodities in monetary values to final consumption. The hybrid methodology has been applied annually between 1995 and 2010 for 21 regional markets globally and including major economies separately (e.g. USA, China, India). Per capita extents and composition of cropland footprints vary widely across the world. Detailed results for Germany and the EU28 highlight the higher land demand of livestock-based diets compared to crop-based diets, the growing integration in international markets, and the growing importance of the non-food sector since 2000. Today the land footprint of each Germany citizen appropriates on average 2693 m2 cropland (about one half for livestock-based diets, one quarter for crop-based diets and one quarter for non-food products). Additional 1655 m2 of grassland per capita are used for the consumption of ruminant livestock products. Germany is a major and increasing trading partner with current net ‘cropland imports’ of 10.6 Mha. Overall, half of Germany’s 22 Mha cropland footprint relies on domestic cultivation and half on land resources abroad. Albeit large uncertainties in the calculation of grassland footprints, results point towards Germany being a significant net importer of grassland embedded in ruminant livestock products

Climate system modeling in the framework of the tolerable windows approach: The ICLIPS climate model

The computational burden associated with applications of theTolerable Windows Approach (TWA) considerably exceeds that oftraditional integrated assessments of global climate change. Aspart of the ICLIPS (Integrated Assessment of Climate ProtectionStrategies) project, a computationally efficient climate model hasbeen developed that can be included in integrated assessmentmodels of any kind. The ICLIPS climate model (ICM) is implementedin GAMS. It is driven by anthropogenic emissions of CO2,CH4, N2O, halocarbons, SF6, andSO2. Theoutput includes transient patterns of near-surface airtemperature, total column-integrated cloud cover fraction,precipitation, humidity, and global mean sea-level rise. Thecarbon cycle module explicitly treats the nonlinear sea watercarbon chemistry and the nonlinear CO2 fertilized biosphereuptake. Patterns of the impact-relevant climate variables arederived form empirical orthogonal function (EOF) analysis andscaled by the principal component of temperature change. Theevolution of the latter is derived from a box-model-typedifferential analogue to its impulse response function convolutionintegral. We present a description of the ICM components and someresults to demonstrate the model's applicability in the TWA setting

The global cropland footprint of the non-food bioeconomy

A rapidly growing share of global agricultural areas is devoted to the production of biomass for non-food purposes. The derived products include, for example, biofuels, textiles, detergents or cosmetics. Given the far-reaching global implications of an expanding non-food bioeconomy, an assessment of the bioeconomy’s resource use from a footprint perspective is urgently needed. We determine the global cropland footprint of non-food products with a hybrid land flow accounting model combining data from the Food and Agriculture Organization and the multi-regional input-output model EXIOBASE. The globally interlinked model covers all cropland areas used for the production of crop- and animal-based non-food commodities for the years from 1995 to 2010. We analyse global patterns of raw material producers, processers and consumers of bio-based non-food products, with a particular focus on the European Union. Results illustrate that the EU is a major processer and the number one consumer region of non-food cropland, despite being only the fifth largest producing region. Two thirds of the cropland required to satisfy EU non-food consumption are located in other world regions, giving rise to a significant dependency on imported products and to potential impacts on distant ecosystems. With almost 29% in 2010, oilseed production, used to produce, for example, biofuels, detergents and polymers, represents the dominant share in the EU’s non-food cropland footprint. There is also a significant contribution of more traditional non-food biomass uses such as fibre crops (for textiles) and animal hides and skins (for leather products). Our study emphasises the importance of comprehensively assessing the implications of the non-food bioeconomy expansion as envisaged in various policy strategies, such as the Bioeconomy Strategy of the European Commission

Effectiveness evaluation of STOL transport operations

A short-takeoff and landing (STOL) systems simulation model has been developed and implemented in a computer code (known as STOL OPS) which permits evaluation of the operation of a STOL aircraft and its avionics in a commercial airline operating environment. STOL OPS concentrated on the avionics functions of navigation, guidance, control, communication, hazard aviodance, and systems management. External world factors influencing the operation of the STOL aircraft include each airport and its geometry, air traffic at each airport, air traffic control equipment and procedures, weather (including winds and visibility), and the flight path between each airport served by the route. The development of the STOL OPS program provides NASA a set of computer programs which can be used for detailed analysis of a STOL aircraft and its avionics and permit establishment of system requirements as a function of airline mission performance goals

The tolerable windows approach: Theoretical and methodological foundations

The tolerable windows (TW) approach is presented as a novel scheme for integrated assessment of climate change. The TW approach is based on the specification of a set of guardrails for climate evolution which refer to various climate-related attributes. These constraints, which define what we call tolerable windows, can be purely systemic in nature - like critical thresholds for the North Atlantic Deep Water formation - or of a normative type - like minimum standards for per-capita food production worldwide. Starting from this catalogue of knock-out criteria and using appropriate modeling techniques, those policy strategies which are compatible with all the constraints specified are sought to be identified. In addition to the discussion of the basic elements and the general theory of the TW approach, a modeling exercise is carried out, based on simple models and assumptions adopted from the German Advisory Council on Global Change (WBGU). The analysis shows that if the global mean temperature is restricted to 2 degrees C beyond the preindustrial level, the cumulative emissions of CO2 are asymptotically limited to about 1550 Gt C. Yet the temporal distribution of these emissions is also determined by the climate and socio-economic constraints: using, for example, a maximal tolerable rate of temperature change of 0.2 degrees C/ dec and a smoothly varying emissions profile, we obtain the maximal cumulative emissions, amounting to 370 Gt C in 2050 and 585 Gt C in 2100

Competition effects of simultaneous application of flexibility options within an energy community

As part of an increased diffusion of decentralized renewable energy technologies, an additional need for flexibility arises. Studies indicate that operating battery storage systems for multiple uses as community electricity storage system (CES) promises superior benefits. This seems decisive, since cheaper flexibility options such as demand response (DR) are more applicable and might further reduce the market size for storage facilities. This research paper aims to analyze the competition effects of CES with simultaneous application of DR. The optimization results of the synthetic case studies provide insights in the profitability level, the service provision and the flexibility potential. While even under requested legal circumstances a CES is only partially profitable, the economic situation improves in terms of an optimal storage utilization. This, however, is reduced through competition effects with DR