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Using the NANA toolkit at home to predict older adults' future depression
Background: Depression is currently underdiagnosed among older adults. As part of the Novel Assessment of Nu-trition and Aging (NANA) validation study, 40 older adults self-reported their mood using a touchscreen computer over three, one-week periods. Here, we demonstrate the potential of these data to predict future depression status.
Methods: We analysed data from the NANA validation study using a machine learning approach. We applied the least absolute shrinkage and selection operator with a logistic model to averages of six measures of mood, with depression status according to the Geriatric Depression Scale 10 weeks later as the outcome variable. We tested multiple values of the selection parameter in order to produce a model with low deviance. We used a cross-validation framework to avoid overspecialisation, and receiver operating characteristic curve (ROC) analysis to determine the quality of the fitted model.
Results: The model we report contained coefficients for two variables: sadness and tiredness, as well as a constant. The cross-validated area under the ROC curve for this model was 0.88 (CI: 0.69–0.97).
Limitations: While results are based on a small sample, the methodology for the selection of variables appears suitable for the problem at hand, suggesting promise for a wider study and ultimate deployment with older adults at increased risk of depression.
Conclusions: We have identified self-reported scales of sadness and tiredness as sensitive measures which have the potential to predict future depression status in older adults, partially addressing the problem of underdiagnosis
Resummation of mass terms in perturbative massless quantum field theory
The neutral massless scalar quantum field in four-dimensional
space-time is considered, which is subject to a simple bilinear
self-interaction. Is is well-known from renormalization theory that adding a
term of the form to the Lagrangean has the formal
effect of shifting the particle mass from the original zero value to m after
resummation of all two-leg insertions in the Feynman graphs appearing in the
perturbative expansion of the S-matrix. However, this resummation is
accompanied by some subtleties if done in a proper mathematical manner.
Although the model seems to be almost trivial, is shows many interesting
features which are useful for the understanding of the convergence behavior of
perturbation theory in general. Some important facts in connection with the
basic principles of quantum field theory and distribution theory are
highlighted, and a remark is made on possible generalizations of the
distribution spaces used in local quantum field theory. A short discussion how
one can view the spontaneous breakdown of gauge symmetry in massive gauge
theories within a massless framework is presented.Comment: 15 pages, LaTeX (style files included), one section adde
Real-time gauge/gravity duality: Prescription, Renormalization and Examples
We present a comprehensive analysis of the prescription we recently put
forward for the computation of real-time correlation functions using
gauge/gravity duality. The prescription is valid for any holographic
supergravity background and it naturally maps initial and final data in the
bulk to initial and final states or density matrices in the field theory. We
show in detail how the technique of holographic renormalization can be applied
in this setting and we provide numerous illustrative examples, including the
computation of time-ordered, Wightman and retarded 2-point functions in
Poincare and global coordinates, thermal correlators and higher-point
functions.Comment: 85 pages, 13 figures; v2: added comments and reference
An illustrated key to male Actinote from Southeastern Brazil (Lepidoptera, Nymphalidae)
Thermal analysis of production of resonances in relativistic heavy-ion collisions
Production of resonances is considered in the framework of the
single-freeze-out model of ultra-relativistic heavy ion collisions. The
formalism involves the virial expansion, where the probability to form a
resonance in a two-body channel is proportional to the derivative of the
phase-shift with respect to the invariant mass. The thermal model incorporates
longitudinal and transverse flow, as well as kinematic cuts of the STAR
experiment at RHIC. We find that the shape of the pi+ pi- spectral line
qualitatively reproduces the preliminary experimental data when the position of
the rho peak is lowered. This confirms the need to include the medium effects
in the description of the RHIC data. We also analyze the transverse-momentum
spectra of rho, K*(892), and f_0(980), and find that the slopes agree with the
observed values. Predictions are made for eta, eta', omega, phi, Lambda(1520),
and Sigma(1385).Comment: minor modifications, a reference adde
Quantum Characterization of a Werner-like Mixture
We introduce a Werner-like mixture [R. F. Werner, Phys. Rev. A {\bf 40}, 4277
(1989)] by considering two correlated but different degrees of freedom, one
with discrete variables and the other with continuous variables. We evaluate
the mixedness of this state, and its degree of entanglement establishing its
usefulness for quantum information processing like quantum teleportation. Then,
we provide its tomographic characterization. Finally, we show how such a
mixture can be generated and measured in a trapped system like one electron in
a Penning trap.Comment: 8 pages ReVTeX, 8 eps figure
Spin dynamics of wave packets evolving with the Dirac Hamiltonian in atoms with high Z
The motion of circular WP for one electron in central Coulomb field with high
Z is calculated. The WP is defined in terms of solutions of the Dirac equation
in order to take into account all possible relevant effects in particular the
spin-orbit potential. A time scale is defined within which spin dynamics must
be taken into account mainly in the atoms with high Z. Within this time scale
there exists a mechanism of collapses and revivals of the spin already shown by
the authors for harmonic oscillator potential and called the 'spin-orbit
pendulum'. However this effect has not the exact periodicity of the simpler
model, but the WP's spatial motion is nevertheless quite similar.Comment: 17 pages, 9 figures, LaTeX2e, uses IOP style files (included). Title
changed, one reference adde
Breakup of F on Pb near the Coulomb barrier
Angular distributions of oxygen produced in the breakup of F incident
on a Pb target have been measured around the grazing angle at beam
energies of 98 and 120 MeV. The data are dominated by the proton stripping
mechanism and are well reproduced by dynamical calculations. The measured
breakup cross section is approximately a factor of 3 less than that of fusion
at 98 MeV. The influence of breakup on fusion is discussed.Comment: 7 pages, 8 figure
A microsatellite marker for yellow rust resistance in wheat
Bulk segregant analysis (BSA) was used to identify molecular markers associated with yellow rust disease resistance in wheat (Triticum aestivum L.). DNAs isolated from the selected yellow rust tolerant and susceptible F-2 individuals derived from a cross between yellow rust resistant and susceptible wheat genotypes were used to established a "tolerant" and a "susceptible" DNA pool. The BSA was then performed on these DNA pools using 230 markers that were previously mapped onto the individual wheat chromosomes. One of the SSR markers (Xgwm382) located on chromosome group 2 (A, B, D genomes) was present in the resistant parent and the resistant bulk but not in the susceptible parent and the susceptible bulk, suggesting that this marker is linked to a yellow rust resistance gene. The presence of Xgwm382 was also tested in 108 additional wheat genotypes differing in yellow rust resistance. This analysis showed that 81% of the wheat genotypes known to be yellow rust resistant had the Xgwm382 marker, further suggesting that the presence of this marker correlates with yellow rust resistance in diverse wheat germplasm. Therefore, Xgwm382 could be useful for marker assisted selection of yellow rust resistances genotypes in wheat breeding programs
Material screening and selection for XENON100
Results of the extensive radioactivity screening campaign to identify
materials for the construction of XENON100 are reported. This Dark Matter
search experiment is operated underground at Laboratori Nazionali del Gran
Sasso (LNGS), Italy. Several ultra sensitive High Purity Germanium detectors
(HPGe) have been used for gamma ray spectrometry. Mass spectrometry has been
applied for a few low mass plastic samples. Detailed tables with the
radioactive contaminations of all screened samples are presented, together with
the implications for XENON100.Comment: 8 pages, 1 figur
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