A Cross-Correlation Analysis of Mg II Absorption Line Systems and Luminous Red Galaxies from the SDSS DR5

We analyze the cross-correlation of 2,705 unambiguously intervening Mg II (2796,2803A) quasar absorption line systems with 1,495,604 luminous red galaxies (LRGs) from the Fifth Data Release of the Sloan Digital Sky Survey within the redshift range 0.36<=z<=0.8. We confirm with high precision a previously reported weak anti-correlation of equivalent width and dark matter halo mass, measuring the average masses to be log M_h(M_[solar]h^-1)=11.29 [+0.36,-0.62] and log M_h(M_[solar]h^-1)=12.70 [+0.53,-1.16] for systems with W[2796A]>=1.4A and 0.8A<=W[2796A]<1.4A, respectively. Additionally, we investigate the significance of a number of potential sources of bias inherent in absorber-LRG cross-correlation measurements, including absorber velocity distributions and the weak lensing of background quasars, which we determine is capable of producing a 20-30% bias in angular cross-correlation measurements on scales less than 2'. We measure the Mg II - LRG cross-correlation for 719 absorption systems with v<60,000 km s^-1 in the quasar rest frame and find that these associated absorbers typically reside in dark matter haloes that are ~10-100 times more massive than those hosting unambiguously intervening Mg II absorbers. Furthermore, we find evidence for evolution of the redshift number density, dN/dz, with 2-sigma significance for the strongest (W>2.0A) absorbers in the DR5 sample. This width-dependent dN/dz evolution does not significantly affect the recovered equivalent width-halo mass anti-correlation and adds to existing evidence that the strongest Mg II absorption systems are correlated with an evolving population of field galaxies at z<0.8, while the non-evolving dN/dz of the weakest absorbers more closely resembles that of the LRG population.Comment: 21 pages, 19 figures; Published in Astrophysical Journa

Bostonia: The Boston University Alumni Magazine. Volume 12

Founded in 1900, Bostonia magazine is Boston University’s main alumni publication

Outbreaks of Imipenem Resistant Acinetobacter Baumannii Producing OXA-23 β-Lactamase in a Tertiary Care Hospital in Korea

Hee University Hospital in Seoul, Korea. The purpose of this study was to determine the genetic basis and molecular epidemiology of outbreak isolates. Materials and Methods: Forty-nine non-repetitive isolates of the 734 IRAB strains were investigated in order to determine their characteristics. The modified Hodge and the ethylenediaminetetraacetic acid (EDTA)-disk synergy test were performed for the screening of carbapenemase and metallo-β-lactamase production. Multiplex polymerase chain reaction (PCR) assays were performed for the detection of genes encoding for OXA-23-like, OXA-24-like, OXA-58-like and OXA-51-like carbapenemase. Pulsed-field gel electrophoresis (PFGE) was performed for strain identification. Results: All isolates showed 100% resistance to ciprofloxacin and gentamicin, 97.9 % resistance to cefepime, piperacillin/tazobactam, aztreonam, ceftazidime and piperacillin, 93.9 % resistance to tobramycin and 57.1 % resistance to amikacin. All of the 49 isolates (100%) showed positive results in the modified Hodge test and negative results in the EDTA-disk synergy test. They all (100%) possessed the encoding gene for an intrinsic OXA-51-like carbapenemase and an acquired OXA-23-like carbapenemase in the multiplex PCR assay. PFGE patterns revealed that all isolates were clonally related from A1 to A14. Conclusion: It is concluded that all of the 49 IRAB isolates acquired resistance t

Long-term influence of normal variation in neonatal characteristics on human brain development

It is now recognized that a number of cognitive, behavioral, and mental health outcomes across the lifespan can be traced to fetal development. Although the direct mediation is unknown, the substantial variance in fetal growth, most commonly indexed by birth weight, may affect lifespan brain development. We investigated effects of normal variance in birth weight on MRI-derived measures of brain development in 628 healthy children, adolescents, and young adults in the large-scale multicenter Pediatric Imaging, Neurocognition, and Genetics study. This heterogeneous sample was recruited through geographically dispersed sites in the United States. The influence of birth weight on cortical thickness, surface area, and striatal and total brain volumes was investigated, controlling for variance in age, sex, household income, and genetic ancestry factors. Birth weight was found to exert robust positive effects on regional cortical surface area in multiple regions as well as total brain and caudate volumes. These effects were continuous across birth weight ranges and ages and were not confined to subsets of the sample. The findings show that (i) aspects of later child and adolescent brain development are influenced at birth and (ii) relatively small differences in birth weight across groups and conditions typically compared in neuropsychiatric research (e.g., Attention Deficit Hyperactivity Disorder, schizophrenia, and personality disorders) may influence group differences observed in brain parameters of interest at a later stage in life. These findings should serve to increase our attention to early influences

Multimodal imaging of the self-regulating developing brain

Self-regulation refers to the ability to control behavior, cognition, and emotions, and self-regulation failure is related to a range of neuropsychiatric problems. It is poorly understood how structural maturation of the brain brings about the gradual improvement in self-regulation during childhood. In a large-scale multicenter effort, 735 children (4-21 y) underwent structural MRI for quantification of cortical thickness and surface area and diffusion tensor imaging for quantification of the quality of major fiber connections. Brain development was related to a standardized measure of cognitive control (the flanker task from the National Institutes of Health Toolbox), a critical component of self-regulation. Ability to inhibit responses and impose cognitive control increased rapidly during preteen years. Surface area of the anterior cingulate cortex accounted for a significant proportion of the variance in cognitive performance. This finding is intriguing, because characteristics of the anterior cingulum are shown to be related to impulse, attention, and executive problems in neurodevelopmental disorders, indicating a neural foundation for self-regulation abilities along a continuum from normality to pathology. The relationship was strongest in the younger children. Properties of large-fiber connections added to the picture by explaining additional variance in cognitive control. Although cognitive control was related to surface area of the anterior cingulate independently of basic processes of mental speed, the relationship between white matter quality and cognitive control could be fully accounted for by speed. The results underscore the need for integration of different aspects of brain maturation to understand the foundations of cognitive development

The Global Burden of Disease Study 2010: Interpretation and Implications for the Neglected Tropical Diseases

This article analyzes the "Global Burden of Disease Study 2010" and examines the study's implications for neglected tropical diseases