2,095 research outputs found
Econometric Modeling of Enrollment Behavior
This paper describes using econometric modeling techniques to analyze the enrollment behavior of admitted students at four-year colleges and universities. It is based on the author\u27s work over the last four years with approximately two dozen institutions seeking to understand more about the behavior of their admitted students-especially those requesting financial aid. This approach to modeling enrollment behavior has been discussed frequently in the literature and has been adopted or attempted at a number of institutions. Here, schools\u27 experiences with such an approach are examined. We look at a wide spectrum of institutions differing by size, selectivity, and program focus
The Seal Cove Shipwreck Project: Investigating an Historical Wooden Vessel on Mount Desert Island, Maine
Two one-week field projects, carried out during the summers of 2011 and 2012, investigated an historical wooden shipwreck in the intertidal zone on the western side of Mount Desert Island, Maine. Salvage, tide, ice, and other environmental forces have reduced the wreck to a keel, frames, and outer hull planking. Despite this, some observations can be made from the limited surviving evidence. The vessel appears to have been heavily-built, with a full-bodied hull, and constructed in the mid to late 19th century. Its location, hull, and the wood shavings and brick chips found between its timbers suggest that it may represent a sailing vessel engaged in the coasting trade. Archaeological investigation of the site also served as an informal field school, providing experience in maritime site recording to Acadia National Park staff and members of the public
High resolution Late-glacial and early-Holocene summer air temperature records from Scotland inferred from Chironomid assemblages
Lateglacial and early-Holocene mean July air temperatures have been reconstructed, using a chironomid-based inference model, from lake-sediment sequences from Abernethy Forest, in the eastern Highlands of Scotland, and Loch Ashik, on the Isle of Skye in north-west Scotland. Chronology for Abernethy Forest was derived from radiocarbon dates of terrestrial plant macrofossils deposited in the lake sediments. Chronology for Loch Ashik was derived from tephra layers of known ages, the first age-depth model of this kind. Chironomid-inferred temperatures peak early in the Lateglacial Interstadial and then gradually decline by about 1 °C to the beginning of the Younger Dryas (YD). At Abernethy Forest, the Lateglacial Interstadial is punctuated by three centennial-scale cold oscillations which appear to be synchronous with the Greenland Interstadial events GI-1d, when temperatures at Abernethy fell by 5.9 °C, GI-1c, when temperatures fell by 2.3 °C, and GI-1b, when temperatures fell by 2.8 °C. At Loch Ashik only the oscillation correlated with GI-1d is clearly defined, when temperatures fell by 3.8 °C. The start of the YD is clearly marked at both sites when temperatures fell by 5.5 °C at Abernethy Forest and 2.8 °C at Loch Ashik. A warming trend is apparent during the late-YD at Abernethy Forest but at Loch Ashik late-YD temperatures became very cold, possibly influenced by its close proximity to the Skye ice-field. The rapidly rising temperatures at the YD – Holocene transition occur about 300 years earlier at both sites than changes in sediment lithology and loss-on-ignition. The temperature trends at both sites are broadly similar, although between-site differences may result from the influence of local factors. Similar climate trends are found at other sites in the northern British Isles. However, the British summer temperature records differ in detail from trends in the oxygen-isotope records from the Greenland ice-cores and from other chironomid-inferred temperature records available from Scandinavia, north-west Europe and central Europe, which suggest important differences in the influence of climatic forcing at regional scales.publishedVersio
Spin-dynamics of the low-dimensional magnet (CH3)2NH2CuCl3
Dimethylammonium copper (II) chloride (also known as DMACuCl3 or MCCL) is a
low dimensional S=1/2 quantum spin system proposed to be an alternating
ferro-antiferromagnetic chain with similar magnitude ferromagnetic (FM) and
antiferromagnetic (AFM) exchange interactions. Subsequently, it was shown that
the existing bulk measurements could be adequately modeled by considering
DMACuCl3 as independent AFM and FM dimer spin pairs. We present here new
inelastic neutron scattering measurements of the spin-excitations in single
crystals of DMACuCl3. These results show significant quasi-one-dimensional
coupling, however the magnetic excitations do not propagate along the expected
direction. We observe a band of excitations with a gap of 0.95 meV and a
bandwidth of 0.82 meV.Comment: 3 pages, 2 figures included in text, submitted to proceedings of
International Conference on Neutron Scattering, December 200
Patterns of training volume and injury risk in elite rugby union: an analysis of 1.5 million hours of training exposure over eleven seasons
Rugby union is a popular team sport that demands high levels of physical fitness and skill. The study aim was to examine trends in training volume and its impact on injury incidence, severity and burden over an 11-season period in English professional rugby. Data were recorded from 2007/08 through 2017/18, capturing 1,501,606 h of training exposure and 3,782 training injuries. Players completed, on average, 6 h 48 minutes of weekly training (95% CI: 6 h 30 mins to 7 h 6 mins): this value remained stable over the 11 seasons. The mean incidence of training-related injuries was 2.6/1000 player-hours (95% CI: 2.4 to 2.8) with a mean severity rising from 17 days in 2007/08 to 37 days in 2017/18 (Change/season = 1.773, P <0.01). Rate of change in severity was dependent on training type, with conditioning (non-gym-based) responsible for the greatest increase (2.4 days/injury/season). As a result of increasing severity, injury burden rose from 51 days absence/1000 player-hours in 2007/08 to 106 days’ absence/1000 player-hours in 2017/18. Despite the low incidence of injury in training compared to match-play, training accounted for 34% of all injuries. Future assessments of training intensity may lead to a greater understanding of the rise in injury severity.</p
SpinWaves in the Frustrated Kagomé Lattice Antiferromagnet KFe\u3csub\u3e3\u3c/sub\u3e(OH)\u3csub\u3e6\u3c/sub\u3e(SO\u3csub\u3e4\u3c/sub\u3e)\u3csub\u3e2\u3c/sub\u3e
The spin wave excitations of the S = 5/2 kagomé lattice antiferromagnet KFe3(OH)6(SO4)2 have been measured using high-resolution inelastic neutron scattering. We directly observe a flat mode which corresponds to a lifted ‘‘zero energy mode,’’ verifying a fundamental prediction for the kagomé lattice. A simple Heisenberg spin Hamiltonian provides an excellent fit to our spin wave data. The antisymmetric Dzyaloshinskii-Moriya interaction is the primary source of anisotropy and explains the low-temperature magnetization and spin structure
Fennoscandian freshwater control on Greenland hydroclimate shifts at the onset of the Younger Dryas
Sources and timing of freshwater forcing relative to hydroclimate shifts recorded in Greenland ice cores at the onset of Younger Dryas, ∼12,800 years ago, remain speculative. Here we show that progressive Fennoscandian Ice Sheet (FIS) melting 13,100–12,880 years ago generates a hydroclimate dipole with drier–colder conditions in Northern Europe and wetter–warmer conditions in Greenland. FIS melting culminates 12,880 years ago synchronously with the start of Greenland Stadial 1 and a large-scale hydroclimate transition lasting ∼180 years. Transient climate model simulations forced with FIS freshwater reproduce the initial hydroclimate dipole through sea-ice feedbacks in the Nordic Seas. The transition is attributed to the export of excess sea ice to the subpolar North Atlantic and a subsequent southward shift of the westerly winds. We suggest that North Atlantic hydroclimate sensitivity to FIS freshwater can explain the pace and sign of shifts recorded in Greenland at the climate transition into the Younger Dryas
Aquatic community response to volcanic eruptions on the Ecuadorian Andean flank: evidence from the palaeoecological record
Aquatic ecosystems in the tropical Andes are under increasing pressure from human modification of the landscape (deforestation and dams) and climatic change (increase of extreme events and 1.5 °C on average temperatures are projected for AD 2100). However, the resilience of these ecosystems to perturbations is poorly understood. Here we use a multi-proxy palaeoecological approach to assess the response of aquatic ecosystems to a major mechanism for natural disturbance, volcanic ash deposition. Specifically, we present data from two Neotropical lakes located on the eastern Andean flank of Ecuador. Laguna Pindo (1°27.132′S–78°04.847′W) is a tectonically formed closed basin surrounded by a dense mid-elevation forest, whereas Laguna Baños (0°19.328′S–78°09.175′W) is a glacially formed lake with an inflow and outflow in high Andean Páramo grasslands. In each lake we examined the dynamics of chironomids and other aquatic and semi-aquatic organisms to explore the effect of thick (> 5 cm) volcanic deposits on the aquatic communities in these two systems with different catchment features. In both lakes past volcanic ash deposition was evident from four large tephras dated to c.850 cal year BP (Pindo), and 4600, 3600 and 1500 cal year BP (Baños). Examination of the chironomid and aquatic assemblages before and after the ash depositions revealed no shift in composition at Pindo, but a major change at Baños occurred after the last event around 1500 cal year BP. Chironomids at Baños changed from an assemblage dominated by Pseudochironomus and Polypedilum nubifer-type to Cricotopus/Paratrichocladius type-II, and such a dominance lasted for approximately 380 years. We suggest that, despite potential changes in the water chemistry, the major effect on the chironomid community resulted from the thickness of the tephra being deposited, which acted to shallow the water body beyond a depth threshold. Changes in the aquatic flora and fauna at the base of the trophic chain can promote cascade effects that may deteriorate the ecosystem, especially when already influenced by human activities, such as deforestation and dams, which is frequent in the high Andes
Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies.
IntroductionQuantitative in vivo measurement of brain amyloid burden is important for both research and clinical purposes. However, the existence of multiple imaging tracers presents challenges to the interpretation of such measurements. This study presents a direct comparison of Pittsburgh compound B-based and florbetapir-based amyloid imaging in the same participants from two independent cohorts using a crossover design.MethodsPittsburgh compound B and florbetapir amyloid PET imaging data from three different cohorts were analyzed using previously established pipelines to obtain global amyloid burden measurements. These measurements were converted to the Centiloid scale to allow fair comparison between the two tracers. The mean and inter-individual variability of the two tracers were compared using multivariate linear models both cross-sectionally and longitudinally.ResultsGlobal amyloid burden measured using the two tracers were strongly correlated in both cohorts. However, higher variability was observed when florbetapir was used as the imaging tracer. The variability may be partially caused by white matter signal as partial volume correction reduces the variability and improves the correlations between the two tracers. Amyloid burden measured using both tracers was found to be in association with clinical and psychometric measurements. Longitudinal comparison of the two tracers was also performed in similar but separate cohorts whose baseline amyloid load was considered elevated (i.e., amyloid positive). No significant difference was detected in the average annualized rate of change measurements made with these two tracers.DiscussionAlthough the amyloid burden measurements were quite similar using these two tracers as expected, difference was observable even after conversion into the Centiloid scale. Further investigation is warranted to identify optimal strategies to harmonize amyloid imaging data acquired using different tracers
MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models
Comparative metabolic modelling is emerging as a novel field, supported by the development of reliable and standardized approaches for constructing genome-scale metabolic models in high throughput. New software solutions are needed to allow efficient comparative analysis of multiple models in the context of multiple cellular objectives. Here, we present the user-friendly software framework Multi-Metabolic Evaluator (MultiMetEval), built upon SurreyFBA, which allows the user to compose collections of metabolic models that together can be subjected to flux balance analysis. Additionally, MultiMetEval implements functionalities for multi-objective analysis by calculating the Pareto front between two cellular objectives. Using a previously generated dataset of 38 actinobacterial genome-scale metabolic models, we show how these approaches can lead to exciting novel insights. Firstly, after incorporating several pathways for the biosynthesis of natural products into each of these models, comparative flux balance analysis predicted that species like Streptomyces that harbour the highest diversity of secondary metabolite biosynthetic gene clusters in their genomes do not necessarily have the metabolic network topology most suitable for compound overproduction. Secondly, multi-objective analysis of biomass production and natural product biosynthesis in these actinobacteria shows that the well-studied occurrence of discrete metabolic switches during the change of cellular objectives is inherent to their metabolic network architecture. Comparative and multi-objective modelling can lead to insights that could not be obtained by normal flux balance analyses. MultiMetEval provides a powerful platform that makes these analyses straightforward for biologists. Sources and binaries of MultiMetEval are freely available from https://github.com/PiotrZakrzewski/MetEv​al/downloads
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