1,576 research outputs found
Motion-correlated flow distortion and wave-induced biases in air-sea flux measurements from ships
Direct measurements of the turbulent air–sea fluxes of momentum, heat, moisture and gases are often made using sensors mounted on ships. Ship-based turbulent wind measurements are corrected for platform motion using well established techniques, but biases at scales associated with wave and platform motion are often still apparent in the flux measurements. It has been uncertain whether this signal is due to time-varying distortion of the air flow over the platform or to wind–wave interactions impacting the turbulence. Methods for removing such motion-scale biases from scalar measurements have previously been published but their application to momentum flux measurements remains controversial. Here we show that the measured motion-scale bias has a dependence on the horizontal ship velocity and that a correction for it reduces the dependence of the measured momentum flux on the orientation of the ship to the wind. We conclude that the bias is due to experimental error and that time-varying motion-dependent flow distortion is the likely source
CD14 and ALPK1 Affect Expression of Tight Junction Components and Proinflammatory Mediators upon Bacterial Stimulation in a Colonic 3D Organoid Model
Cd14 and Alpk1 both encode pathogen recognition receptors and are known candidate genes for affecting severity in inflammatory bowel diseases. CD14 acts as a coreceptor for bacterial lipopolysaccharide (LPS), while ALPK1 senses ADP-D-glycero-beta-D-manno-heptose, a metabolic intermediate of LPS biosynthesis. Intestinal barrier integrity can be influenced by CD14, whereas to date, the role of ALPK1 in maintaining barrier function remains unknown. We used colon-derived 3D organoids, first characterised for growth, proliferation, stem cell markers, and expression of tight junction (TJ) components using qPCR and immunohistochemistry. They showed characteristic crypt stem cells, apical shedding of dead cells, and TJ formation. Afterwards, organoids of different genotypes (WT, Il10-/-, Cd14-/-, and Alpk1-/-) were then stimulated with either LPS or Escherichia coli Nissle 1917 (EcN). Gene expression and protein levels of cytokines and TJ components were analysed. WT organoids increased expression of Tnfα and tight junction components. Cd14-/- organoids expressed significantly less Tnfα and Ocln after LPS stimulation than WT organoids but reacted similarly to WT organoids after EcN stimulation. In contrast, compared to WT, Alpk1-/- organoids showed decreased expression of different TJ and cytokine genes in response to EcN but not LPS. However, Western blotting revealed an effect of ALPK1 on TJ protein levels. These findings demonstrate that Cd14, but not Alpk1, alters the response to LPS stimulation in colonic epithelial cells, whereas Alpk1 is involved in the response upon bacterial challenge. © 2020 Pascal Brooks et al
System for Corrosion Inspection and Monitoring
This paper contains has conducted research and analysis on different corrosion identification and monitoring methods to develop an autonomous corrosion inspection system to solve the challenge issued by the University Student Design and Applied Solutions Competition. This challenge is to build an autonomous corrosion detection and monitoring system to help provide new ideas and innovations to the Department of Defense. Using research and stakeholder analysis, this research produced a system to best meet the demands of the competition and determine the best possible solution to the design challenge. Our integrated team used a systems engineering approach to produce the design that will be fielded at the competition in April 2016
The role of capital controls in mediating global shocks
To compare the effect of oral glucose given with or without facilitated tucking (FT), versus placebo (water) to facilitate image acquisition during a targeted neonatal echocardiography (TNE).Factorial, double blind, randomized controlled trial.Tertiary neonatal intensive care unit (NICU).Infants born between 26 and 42 weeks of gestation (GA).One of four treatment groups: oral water (placebo), oral glucose (25%), facilitated tucking with oral water or facilitated tucking with oral glucose, during a single, structured TNE. All infants received a soother.Change in Behavioral Indicators of Infant Pain (BIIP) scores.104 preterm infants were randomized (mean ± SD GA: 33.4 ± 3.5 weeks). BIIP scores remained low during the echocardiography scan (median, [IQ range]: 0, [0 to 1]). There were no differences in the level of agitation of infants amongst the treatment groups, with estimated reductions in mean BIIP relative to control of 0.27 (95%CI -0.40 to 0.94) with use of oral glucose and .04 (-0.63 to 0.70) with facilitated tucking. There were also no differences between treatment groups in the quality and duration of the echocardiography scans.In stable infants in the NICU, a TNE can be performed with minimal disruption in a majority of cases, simply by providing a soother. The use of 25% glucose water in this context did not provide further benefit in reducing agitation and improving image acquisition.Clinical Trials.gov: NCT01253889
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Ocean bubbles under high wind conditions – Part 2: Bubble size distributions and implications for models of bubble dynamics
Bubbles formed by breaking waves in the open ocean influence many surface processes but are poorly understood. We report here on detailed bubble size distributions measured during the High Wind Speed Gas Exchange Study (HiWinGS) in the North Atlantic, during four separate storms with hourly averaged wind speeds from 10–27 m s−1. The measurements focus on the deeper plumes formed by advection downwards (at 2 m depth and below), rather than the initial surface distributions. Our results suggest that bubbles reaching a depth of 2 m have already evolved to form a heterogeneous but statistically stable population in the top 1–2 m of the ocean. These shallow bubble populations are carried downwards by coherent near-surface circulations; bubble evolution at greater depths is consistent with control by local gas saturation, surfactant coatings and pressure. We find that at 2 m the maximum bubble radius observed has a very weak wind speed dependence and is too small to be explained by simple buoyancy arguments. For void fractions greater than 10−6, bubble size distributions at 2 m can be fitted by a two-slope power law (with slopes of −0.3 for bubbles of radius <80 µm and −4.4 for larger sizes). If normalised by void fraction, these distributions collapse to a very narrow range, implying that the bubble population is relatively stable and the void fraction is determined by bubbles spreading out in space rather than changing their size over time. In regions with these relatively high void fractions we see no evidence for slow bubble dissolution. When void fractions are below 10−6, the peak volume of the bubble size distribution is more variable and can change systematically across a plume at lower wind speeds, tracking the void fraction. Relatively large bubbles (80 µm in radius) are observed to persist for several hours in some cases, following periods of very high wind. Our results suggest that local gas supersaturation around the bubble plume may have a strong influence on bubble lifetime, but significantly, the gas in the bubbles contained in the deep plumes cannot be responsible for this supersaturation. We propose that the supersaturation is predominately controlled by the dissolution of bubbles in the top metre of the ocean, and that this bulk water is then drawn downwards, surrounding the deep bubble plume and influencing its lifetime. In this scenario, oxygen uptake is associated with deep bubble plumes but is not driven directly by them. We suggest that as bubbles move to depths greater than 2 m, sudden collapse may be more significant as a bubble termination mechanism than slow dissolution, especially in regions of high void fraction. Finally, we present a proposal for the processes and timescales which form and control these deeper bubble plumes
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Ocean bubbles under high wind conditions – Part 1: Bubble distribution and development
The bubbles generated by breaking waves are of considerable scientific interest due to their influence on air–sea gas transfer, aerosol production, and upper ocean optics and acoustics. However, a detailed understanding of the processes creating deeper bubble plumes (extending 2–10 m below the ocean surface) and their significance for air–sea gas exchange is still lacking. Here, we present bubble measurements from the HiWinGS expedition in the North Atlantic in 2013, collected during several storms with wind speeds of 10–27 m s−1. A suite of instruments was used to measure bubbles from a self-orienting free-floating spar buoy: a specialised bubble camera, acoustical resonators, and an upward-pointing sonar. The focus in this paper is on bubble void fractions and plume structure. The results are consistent with the presence of a heterogeneous shallow bubble layer occupying the top 1–2 m of the ocean, which is regularly replenished by breaking waves, and deeper plumes which are only formed from the shallow layer at the convergence zones of Langmuir circulation. These advection events are not directly connected to surface breaking. The void fraction distributions at 2 m depth show a sharp cut-off at a void fraction of 10−4.5 even in the highest winds, implying the existence of mechanisms limiting the void fractions close to the surface. Below wind speeds of 16 m s−1 or a wind-wave Reynolds number of RHw = 2×106, the probability distribution of void fraction at 2 m depth is very similar in all conditions but increases significantly above either threshold. Void fractions are significantly different during periods of rising and falling winds, but there is no distinction with wave age. There is a complex near-surface flow structure due to Langmuir circulation, Stokes drift, and wind-induced current shear which influences the spatial distribution of bubbles within the top few metres. We do not see evidence for slow bubble dissolution as bubbles are carried downwards, implying that collapse is the more likely termination process. We conclude that the shallow and deeper bubble layers need to be studied simultaneously to link them to the 3D flow patterns in the top few metres of the ocean. Many open questions remain about the extent to which deep bubble plumes contribute to air–sea gas transfer. A companion paper (Czerski et al., 2022) addresses the observed bubble size distributions and the processes responsible for them
Near-surface measurements of sea spray aerosol production over whitecaps in the open ocean
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Anxious and egocentric: How specific emotions influence perspective taking
People frequently feel anxious. Although prior research has extensively studied how feeling anxious shapes intrapsychic aspects of cognition, much less is known about how anxiety affects interpersonal aspects of cognition. Here, we examine the influence of incidental experiences of anxiety on perceptual and conceptual forms of perspective taking. Compared with participants experiencing other negative, high-arousal emotions (i.e., anger or disgust) or neutral feelings, anxious participants displayed greater egocentrism in their mental-state reasoning: They were more likely to describe an object using their own spatial perspective, had more difficulty resisting egocentric interference when identifying an object from others’ spatial perspectives, and relied more heavily on privileged knowledge when inferring others’ beliefs. Using both experimental-causal-chain and measurement-of-mediation approaches, we found that these effects were explained, in part, by uncertainty appraisal tendencies. Further supporting the role of uncertainty, a positive emotion associated with uncertainty (i.e., surprise) produced increases in egocentrism that were similar to anxiety. Collectively, the results suggest that incidentally experiencing emotions associated with uncertainty increase reliance on one’s own egocentric perspective when reasoning about the mental states of others
Can Subphotospheric Magnetic Reconnection Change the Elemental Composition in the Solar Corona?
Within the coronae of stars, abundances of those elements with low first ionization potential (FIP) often differ from their photospheric values. The coronae of the Sun and solar-type stars mostly show enhancements of low-FIP elements (the FIP effect) while more active stars such as M dwarfs have coronae generally characterized by the inverse-FIP effect (I-FIP). Here we observe patches of I-FIP effect solar plasma in AR 12673, a highly complex βγδ active region. We argue that the umbrae of coalescing sunspots, and more specifically strong light bridges within the umbrae, are preferential locations for observing I-FIP effect plasma. Furthermore, the magnetic complexity of the active region and major episodes of fast flux emergence also lead to repetitive and intense flares. The induced evaporation of the chromospheric plasma in flare ribbons crossing umbrae enables the observation of four localized patches of I-FIP effect plasma in the corona of AR 12673. These observations can be interpreted in the context of the ponderomotive force fractionation model which predicts that plasma with I-FIP effect composition is created by the refraction of waves coming from below the chromosphere. We propose that the waves generating the I-FIP effect plasma in solar active regions are generated by subphotospheric reconnection of coalescing flux systems. Although we only glimpse signatures of I-FIP effect fractionation produced by this interaction in patches on the Sun, on highly active M stars it may be the dominant process
Orbital selective coupling in CeRhB: co-existence of high Curie and high Kondo temperature
We investigated the electronic structure of the enigmatic CeRhB using
resonant inelastic scattering and x-ray absorption spectroscopy in combination
with density functional calculations. We find that the Rh 4
states are irrelevant for the high-temperature ferromagnetism and the Kondo
effect. We also find that the Ce 4 crystal-field strength is too small to
explain the strong reduction of the Ce magnetic moment. The data reveal instead
the presence of two different active Ce 4 orbitals, with each coupling
selectively to different bands in CeRhB. The inter-site hybridization
of the |J=5/2,Jz=+/-1/2> crystal-field state and Ce 5 band combined with the
intra-site Ce 4-5 exchange creates the strong ferromagnetism, while
hybridization between the |J=5/2,Jz=+/-5/2> and the B in the -plane
contributes to the Kondo interaction which causes the moment reduction. This
orbital selective coupling explains the unique and seemingly contradictory
properties of CeRhB.Comment: 15 pages, 14 figure
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