290 research outputs found
Two-Dimensional High Performance Liquid Chromatography-Mass Spectrometry for Phosphatidylcholine Analysis in Egg Yolk
An early history of T cell-mediated cytotoxicity.
After 60 years of intense fundamental research into T cell-mediated cytotoxicity, we have gained a detailed knowledge of the cells involved, specific recognition mechanisms and post-recognition perforin-granzyme-based and FAS-based molecular mechanisms. What could not be anticipated at the outset was how discovery of the mechanisms regulating the activation and function of cytotoxic T cells would lead to new developments in cancer immunotherapy. Given the profound recent interest in therapeutic manipulation of cytotoxic T cell responses, it is an opportune time to look back on the early history of the field. This Timeline describes how the early findings occurred and eventually led to current therapeutic applications
Multivariate analyses of cellular fatty acids and carbohydrates of 1:2:1 and 2:4:2 spirochetes
Relationship between humoral and cellular isoantibodies. I. Inability of humoral isoantibodies to prevent the cytotoxic effect of immune lymphocytes.
Relationship between haemagglutinating and cytotoxic properties of humoral isoantibodies.
Cross-reactivity of Cytotoxic T-Lymphocyte Antigen-binding Receptors Immune to Antigens of the H-2 System
(in Vitro and in vivo study of the cytotoxic effect of \u27cellular\u27 and humoral isoantibodies.) (eng. Summ.)
- …