CANCER DU COL, DYSPLASIE, DYSPLASIE SEVERE, MICRO INVASION : CARACTERISTIQUE DE LA PRISE EN CHARGE PENDANT la grossesse ?

Approximately 30% of cervical cancers occur in women of childbearing age. In early pregnancy , it is now recommended that a new cervical cytology if the previous rise to 2 years or more , or in the absence of regular monitoring. The methods of conventional cytology smears or said liquid medium are easily achievable. Pregnancy makes available the junction area and changes of pregnancy do not reduce the diagnostic value of smears after informing the cytologist. During pregnancy colposcopy examination remains essential to assess the cytological abnormalities . If the smear shows a high-grade lesion , an ASC- H, or low - grade and ASC-US or glandular atypia (AGC) colposcopy and directed biopsy is performed. Rates dysplasia found is of course variable but to behave similarly. The aim of our work is referred to the particularities of the association of cervical cancer and pregnancy in different diagnostic and therapeutic steps.Environ 30 % des cancers du col surviennent chez des femmes en âge de procréer. En début de grossesse, il est actuellement recommandé de réaliser une nouvelle cytologie cervicale si la précédente remonte à 2 ans ou plus, ou en l’absence de suivi régulier. Les méthodes de cytologie conventionnelle dite de Papanicolaou ou en milieu liquide sont facilement réalisables. La grossesse rend accessible la zone de jonction et les modifications gravidiques ne diminuent pas la valeur diagnostique du frottis après information du cytologiste. Pendant la grossesse la colposcopie demeure l’examen indispensable pour évaluer les anomalies cytologiques. Si le frottis montre une lésion de haut grade, une ASC-H, ou de bas-grade et ASC-US ou une atypie glandulaire (AGC) on réalise une colposcopie et biopsie dirigée .Le taux de dysplasie retrouvé est bien sûr variable mais la conduite à tenir est similaire. Le but de notre travail est d’évoqué les particularités liées à l’association cancer du col et grossesse aux différentes étapes diagnostiques et thérapeutiques

Comparison of energy transfer between Terbium and Ytterbium ions in glass and glass ceramic: Application in photovoltaic

The structural and optical properties of thin layers based on 70%SiO 2 –30%HfO 2 doped with different concentra- tion of rare earth ions (terbium and ytterbium) have been studied with a view to integrating them in a photovoltaic cell as a spectral conversion layer in order to improve its efficiency, by using down-conversion process. These thin films were synthesized by using sol gel technique and deposited on the pure silica substrate by dip-coating method. The DC layer can be placed on the front side of a solar cell and can enhance the current by converting ultraviolet (UV) photons into a large number of visible photons. In present study two series of samples are compared, the first series corresponds to samples treated at 900 °C (glass- S) while the second series concerns samples treated at 1000 °C (glass-ceramic- SC). These series are based on 70SiO 2 –30HfO 2 activated by different molar concentrations of rare earths [Tb + Yb]/[Si + Hf] = 7%, 9%, 12%, 15%, 17%, 19% and 21%. Photoluminescence results of reference samples (without Yb 3 + ) showed an emission from 5 D 4 to 7 F J ( J = 3, 4, 5, 6) level characteristic transitions of Tb 3 + , with a maximum peak in the green centered at 543.5 nm cor- responding to the 5 D 4 →7 F 5 transition. For the co-doped samples a clear NIR PL emission around 980 nm was detected, due to the 2 F 5/2 →2 F 7/2 transition of Yb 3 + ions. From luminescence decay curves of Tb 3 + maximum emission peak ( 7 F 5 →5 D 4 transition at 543.5 nm) we have identified the energy transfer efficiency. The quantum efficiency increases by increasing the total [Tb + Yb] concentration. The most significant yield was achieved with [Tb + Yb] = 19%, the maximum quantum transfer efficiency obtained was 190% for glass-ceramic samples and 161% for glassy one

Sound propagation in density wave conductors and the effect of long-range Coulomb interaction

We study theoretically the sound propagation in charge- and spin-density waves in the hydrodynamic regime. First, making use of the method of comoving frame, we construct the stress tensor appropriate for quasi-one dimensional systems within tight-binding approximation. Taking into account the screening effect of the long-range Coulomb interaction, we find that the increase of the sound velocity below the critical temperature is about two orders of magnitude less for longitudinal sound than for transverse one. It is shown that only the transverse sound wave with displacement vector parallel to the chain direction couples to the phason of the density wave, therefore we expect significant electromechanical effect only in this case.Comment: revtex, 14 pages (in preprint form), submitted to PR

Tb3+/Yb3+ codoped silica-hafnia glass and glass-ceramic waveguides to improve the efficiency of photovoltaic solar cells

In this paper we present the investigation of the energy transfer efficiency between Tb3+ and Yb3+ ions in silica-hafnia waveguides. Cooperative energy transfer between these two ions allows to cut one 488 nm photon in two 980 nm photons and could have important applications in improving the performance of photovoltaic solar cells. Previous works revealed that for a given concentration of donors (Tb3+, increasing the number of acceptors (Yb3+) located near to the Tb3+ ion can increase the Tb-Yb transfer probability. However, when increasing the density of active ions, some detrimental effects due to cross-relaxation mechanisms become relevant. On the basis of this observation the sample doping was chosen keeping constant the molar ratio [Yb]/[Tb] = 4 and the total rare earths contents were [Tb + Yb]/[Si + Hf] = 5%, 7%, 9%. The choice of the matrix is another crucial point to obtain an efficient down conversion processes with rare earth ions. To this respect a 70SiO(2)-30HfO(2) waveguide composition was chosen. The comparison between the glass and the glass-ceramic structures demonstrated that the latter is more efficient since it combines the good optical properties of glasses with the optimal spectroscopic properties of crystals activated by luminescent species. A maximum transfer efficiency of 55% was found for the highest rare earth doping concentration

Surface impedance of BaFe2-xNixAs2 in the radio frequency range

We report measurements of the temperature dependence of the surface impedance in superconducting BaFe1.93Ni0.07As2 crystals using the radiofrequency reflection technique in the 5<T<30K temperature range. An LC resonant circuit with a phase sensitive detection was used at 92MHz. A measurement assembly with point contacts was used at 30MHz. The recent discovery of iron based arsenide superconductors BaFe2-xNixAs2 has attracted much interest. For a Ni doping level of 7% the superconducting phase transition is found around 20K. The temperature dependence of the superconducting penetration depth was determined

Bi(F, O)2.45: An Anion-Excess Fluorite Defect Structure Deriving from Rhombohedral LnFO Type

International audienc

The enigma of the biological interpretation of the linear-quadratic model finally resolved? A summary for non-mathematicians

National audienceLe modèle linéaire-quadratique (LQ) est aujourd’hui la seule relation mathématique liant la survie cellulaire et la dose de radiation qui soit suffisamment consensuelle pour que radiothérapeutes et radiobiologistes l’utilisent régulièrement dans leurs interprétations des phénomènes radioinduits. Pourtant, cette formule proposée dans les années 1970 et les paramètres α et β sur lesquels elle est basée sont restés sans signification biologique cohérente. À partir d’une collection de fibroblastes cutanés de radiosensibilité différente constituée pendant 12 ans par plus de 50 radiothérapeutes français, nous avons mis récemment en évidence que la protéine ATM, acteur majeur de la réponse aux radiations ionisantes, diffuse du cytoplasme au noyau après irradiation. La mise en évidence de ce transit cytonucléaire de la protéine ATM nous a permis de fournir une interprétation biologique cohérente du modèle linéaire-quadratique dans ses aspects les plus mathématiques, validée par une centaine de cas. Une explication mécanistique de la radiosensibilité des syndromes causés par des mutations de protéines cytoplasmiques et du phénomène d’hypersensibilité aux faibles doses a pu être aussi avancée. Dans cette revue, nous avons abordé la résolution de ce modèle linéaire-quadratique de façon didactique, en se limitant strictement aux aspects mathématiques les plus essentiels.The linear-quadratic (LQ) model is the only mathematical formula linking cellular survival and radiation dose that is sufficiently consensual to help radiation oncologists and radiobiologists in describing the radiation-induced events. However, this formula proposed in the 1970s and α and β parameters on which it is based remained without relevant biological meaning. From a collection of cutaneous fibroblasts with different radiosensitivity, built over 12 years by more than 50 French radiation oncologists, we recently pointed out that the ATM protein, major actor of the radiation response, diffuses from the cytoplasm to the nucleus after irradiation. The evidence of this nuclear shuttling of ATM allowed us to provide a biological interpretation of the LQ model in its mathematical features, validated by a hundred of radiosensitive cases. A mechanistic explanation of the radiosensitivity of syndromes caused by the mutation of cytoplasmic proteins and of the hypersensitivity to low-dose phenomenon has been proposed, as well. In this review, we present our resolution of the LQ model in the most didactic way. © 2016 Société française de radiothérapie oncologique (SFRO

Stabilité thermique de quelques apatites sous atmosphère de H

L’étude des apatites calcocadmiées et calcozinciques traitées à différentes températures sous atmosphère de H2S montre l’extraction du Cd et du Zn du réseau apatitique combinés essentiellement sous forme de CdS et ZnS. Dans le cas des hydroxyapatites les ions S2- provenant de la décomposition de H2S se substituent aux ions OH- pour donner une sulfoapatite pure ou altérée avec d’autres phases