Bounding surfaces in a barchan dune: annual cycles of deposition? Seasonality or erosion by superimposed bedforms?

A barchan dune has been surveyed using ground-penetrating radar (GPR) revealing packages of dipping strata within the dune that are truncated by bounding surfaces. The bounding surfaces dip in the downwind direction, truncate sets of cross-stratification, and are themselves downlapped by dipping strata. Models of aeolian strata suggest that the bounding surfaces could be reactivation surfaces, an erosion surface formed when a dune is reshaped by a change in wind. Alternatively, they could be superposition surfaces formed by the migration of smaller bedforms over the dune surface. These two hypotheses are tested using a combination of field and satellite observations. The average annual migration rate for the barchan dune derived from satellite images, gives an annual migration rate of 21.4 myr-1. The number of reactivation surfaces imaged within the dune by GPR appears to scale with the annual migrating rate and dune turnover time suggesting that at this location annual cycles in the wind regime are a potential control on dune stratigraphy with reactivation surfaces generated by changes in the wind direction, including wind reversals in the winter months. Alternatively, it is hypothesized that erosion in the lee of small, superimposed bedforms as they pass the dune crest and approach the brink at the top of the slipface will create superposition surfaces. The migration rate of superimposed bedforms with a wavelength of 20 m has been measured at 2mday-1. This suggest that small-superimposed bedforms will arrive at the dune crest approximately every ten days. Thus bounding surface created by erosion in the lee of superimposed dunes will be very common. Given that the turnover time of the barchan dune is estimated at 4.3 years, the number of superposition surfaces produced by the faster bedforms could be more than 100. The number of bounding surface imaged by a GPR profile along the length of the dune appears to support the wind driven reactivation hypothesis. However, a GPR profile across the dune images many small trough sets, instead of a single slipface, suggesting that superimposed dunes play an important role in the stratigraphy of a relatively simple barchan dune

Lidar technology measurements and technology: Report of panel

Lidar is ready to make an important contribution to tropospheric chemistry research with a variety of spaceborne measurements that complement the measurements from passive instruments. Lidar can now be considered for near-term and far-term space missions dealing with a number of scientifically important issues in tropospheric chemistry. The evolution in the lidar missions from space are addressed and details of these missions are given. The laser availability for space missions based upon the technical data is assessed

The Proper Motion of the Large Magellanic Cloud using HST

We present a measurement of the systemic proper motion of the Large Magellanic Cloud (LMC) from astrometry with the High Resolution Camera (HRC) of the Advanced Camera for Surveys (ACS) on the Hubble Space Telescope (HST). We observed LMC fields centered on 21 background QSOs that were discovered from their optical variability in the MACHO database. The QSOs are distributed homogeneously behind the central few degrees of the LMC. With 2 epochs of HRC data and a ~2 year baseline we determine the proper motion of the LMC to better than 5% accuracy: mu_W = -2.03 +/- 0.08 mas/yr; mu_N = 0.44 +/- 0.05 mas/yr. This is the most accurate proper motion measurement for any Milky Way satellite thus far. When combined with HI data from the Magellanic Stream this should provide new constraints on both the mass distribution of the Galactic Halo and models of the Stream.Comment: 40 pages, 15 figures, submitted to Ap

Database of nitrification and nitrifiers in the global ocean

As a key biogeochemical pathway in the marine nitrogen cycle, nitrification (ammonia oxidation and nitrite oxidation) converts the most reduced form of nitrogen – ammonium–ammonia (NH4+–NH3) – into the oxidized species nitrite (NO2-) and nitrate (NO3-). In the ocean, these processes are mainly performed by ammonia-oxidizing archaea (AOA) and bacteria (AOB) and nitrite-oxidizing bacteria (NOB). By transforming nitrogen speciation and providing substrates for nitrogen removal, nitrification affects microbial community structure; marine productivity (including chemoautotrophic carbon fixation); and the production of a powerful greenhouse gas, nitrous oxide (N2O). Nitrification is hypothesized to be regulated by temperature, oxygen, light, substrate concentration, substrate flux, pH and other environmental factors. Although the number of field observations from various oceanic regions has increased considerably over the last few decades, a global synthesis is lacking, and understanding how environmental factors control nitrification remains elusive. Therefore, we have compiled a database of nitrification rates and nitrifier abundance in the global ocean from published literature and unpublished datasets. This database includes 2393 and 1006 measurements of ammonia oxidation and nitrite oxidation rates and 2242 and 631 quantifications of ammonia oxidizers and nitrite oxidizers, respectively. This community effort confirms and enhances our understanding of the spatial distribution of nitrification and nitrifiers and their corresponding drivers such as the important role of substrate concentration in controlling nitrification rates and nitrifier abundance. Some conundrums are also revealed, including the inconsistent observations of light limitation and high rates of nitrite oxidation reported from anoxic waters. This database can be used to constrain the distribution of marine nitrification, to evaluate and improve biogeochemical models of nitrification, and to quantify the impact of nitrification on ecosystem functions like marine productivity and N2O production. This database additionally sets a baseline for comparison with future observations and guides future exploration (e.g., measurements in the poorly sampled regions such as the Indian Ocean and method comparison and/or standardization). The database is publicly available at the Zenodo repository: https://doi.org/10.5281/zenodo.8355912 (Tang et al., 2023).</p

A prospectus for future geomorphological investigation of the Namib Sand Sea

The Namib Sand Sea in southern Africa offers an ideal location in which to consider general questions about the evolution of sand seas, about the fluxes of sand through contemporary dune fields and about the patterns of dune form that are created. This paper aims to provide a concise account of the approaches and techniques that are currently being used and will be used in the future to address these questions. The paper considers the techniques employed to investigate wind climate, the morphometry of the dunes, the internal structure of dune sediments, the age of the dunes and the potential to model dune development

The Baryon Census in a Multiphase Intergalactic Medium: 30% of the Baryons May Still Be Missing

For low-redshift cosmology and galaxy formation rates, it is important to account for all the baryons synthesized in the Big Bang. Although galaxies and clusters contain 10% of the baryons, many more reside in the photoionized Lyman-alpha forest and shocked-heated warm-hot intergalactic medium (WHIM) at T = 10^5 to 10^7 K. Current tracers of WHIM at 10^5 to 10^6 K include the O VI 1032, 1038 absorption lines, together with broad Lyman-alpha absorbers (BLAs) and EUV/X-ray absorption lines from Ne VIII, O VII, and O VIII. We improve the O VI baryon surveys with corrections for oxygen metallicity (Z/Zsun) and O VI ionization fraction (f_OVI) using cosmological simulations of heating, cooling, and metal transport in a density-temperature structured medium. Statistically, their product correlates with column density, (Z/Zsun)(f_OVI) = (0.015)(N_OVI/10^{14} cm^-2)^0.70. The N_OVI-weighted mean is 0.01, which doubles previous estimates of WHIM baryon content. We also reanalyze H I data from the Hubble Space Telescope, applying redshift corrections for absorber density, photoionizing background, and proper length, dl/dz. We find substantial baryon fractions in the photoionized Lya forest (28 +/- 11%), O VI/BLA-traced WHIM (25 +/- 8%), and collapsed phase (18 +/- 4%) in galaxies, groups, clusters, and circumgalactic gas. The baryon shortfall is 29 +/- 13%, which may be detected in X-ray absorbers from hotter WHIM or in weaker Lya and O VI absorbers. Further progress will require higher-precision baryon surveys of weak absorbers at column densities N_HI > 10^{12.0} cm^-2, N_OVI > 10^{12.5} cm^-2, and N_OVII > 10^{14.5} cm^-2, with moderate-resolution UV and X-ray spectrographs.Comment: 14 pages, 9 figures, revised submission to ApJ (new Fig 2, Appendices A,B

Phase 2 study of canfosfamide in combination with pegylated liposomal doxorubicin in platinum and paclitaxel refractory or resistant epithelial ovarian cancer

<p>Abstract</p> <p>Background</p> <p>Canfosfamide is a novel glutathione analog activated by glutathione S-transferase P1-1. This study evaluated the safety and efficacy of canfosfamide in combination with pegylated liposomal doxorubicin (PLD) in patients with platinum resistant ovarian cancer. Patients with platinum resistant ovarian carcinoma and measurable disease received canfosfamide at 960 mg/m²in combination with PLD at 50 mg/m², intravenously day 1 in every 28 day cycles until tumor progression or unacceptable toxicities. The primary endpoints were objective response rate (ORR) and progression-free survival (PFS).</p> <p>Results</p> <p>Canfosfamide plus PLD combination therapy was administered at 960/50 mg/m², respectively. Thirty-nine patients received a median number of 4 cycles (range 1.0-18.0). The ORR was 27.8% (95% CI, 14.2-45.2) with a disease stabilization rate of 80.6% (95% CI, 64.0-91.8) in the evaluable population. The CA-125 marker responses correlated with the radiological findings of complete response or partial response. The median PFS was 6.0 months (95% CI, 4.2-7.9) and median survival was 17.8 months. The combination was well tolerated. Myelosuppression was managed with dose reductions and growth factor support. Grade 3 febrile neutropenia was observed in 2 patients (5.1%). Non-hematologic adverse events occurred at the expected frequency and grade for each drug alone, with no unexpected or cumulative toxicities.</p> <p>Conclusions</p> <p>Canfosfamide in combination with PLD is well tolerated and active in platinum and paclitaxel refractory or resistant ovarian cancer. A randomized phase 3 study was conducted based on this supportive phase 2 study.</p> <p>Trial Registration</p> <p>This study was registered at www.clinicaltrials.gov: NCT00052065.</p